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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Ariadna Miquel Clopés

Ariadna Miquel Clopés

Research technician
Childhood Cancer and Blood Disorders
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Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
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Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
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Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Ariadna Miquel Clopés

Ariadna Miquel Clopés

Research technician
Childhood Cancer and Blood Disorders
Read more
Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
Read more
Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

Development of mRNA vaccines for children with high-risk neuroblastoma

IP: Miguel Segura Ginard
Collaborators: -
Funding agency: Health Research Charities Ireland (HRCI)
Funding: 26250
Reference: HRCI/JOINT_FUNDING_SCHEME/2022/SEGURA
Duration: 21/11/2022 - 30/08/2026

ERN-EuroBloodNet (European Reference Network on Rare Hematological Diseases)

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Sara Isabel Reidel , Núria Torquet i Luna, Raquel Mosull del Campo, Raquel Mosull del Campo, Alba María Albert Robledo, Claire Diot, Daiana Natali Lopez , Maximo Tartaglia
Funding agency: EUROPEAN COMMISSION
Funding: 1569581.5
Reference: EUROBLOODNET-ERN_MAÑU_EU4H2023
Duration: 01/10/2023 - 30/09/2027

Seniority Josep Romà 2024

IP: Josep Roma Castanyer
Collaborators: -
Funding agency: VHIR
Funding: 296955
Reference: VHIR-SEN-2023-002
Duration: 01/05/2024 - 30/04/2029

La interacción entre el error innato de la inmunidad y los trastornos sanguíneos: desentrañando los defectos inmunitarios detrás de las enfermedades hematológicas comunes

IP: Pere Soler Palacín
Collaborators: Laura Batlle Masó, Maria Cristina Díaz de Heredia Rubio, Roger Colobran Oriol, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Miriam Gonzalez Amores, Janire Perurena Prieto, Andrea Martín Nalda, Lucas Moreno Martín-Retortillo, Jacques Gabriel Rivière
Funding agency: Instituto de Salud Carlos III
Funding: 179993.75
Reference: AC23_2/00033
Duration: 01/01/2024 - 31/12/2026

Blog

News

The projects, selected under the 2026 Health Research and CaixaImpulse Health Innovation calls, address topics ranging from new therapies for childhood neurological disorders and Parkinson’s disease to the treatment of mitochondrial diseases and cancer.

A new publication describes the creation of this initiative, which has facilitated access to genomic studies for more than 900 pediatric patients with cancer from across Spain.

The families of the professionals had the opportunity to visit the facilities and discover how we work at the institution.