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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Judith Canto Santos

Judith Canto Santos

Research technician
Childhood Cancer and Blood Disorders
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Julia Piqué Ponti

Julia Piqué Ponti

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Luz Elena Valderrama Orenday

Luz Elena Valderrama Orenday

Research technician
Childhood Cancer and Blood Disorders
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Judith Canto Santos

Judith Canto Santos

Research technician
Childhood Cancer and Blood Disorders
Read more
Julia Piqué Ponti

Julia Piqué Ponti

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
Read more
Luz Elena Valderrama Orenday

Luz Elena Valderrama Orenday

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

Development of prognostic and therapeutic tools targeting epigenetic regulators in metastatic neuroblastoma

IP: Miguel Segura Ginard
Collaborators: Maria Jose Pérez García, Lorena Valero Arrese, Adria Molero Valenzuela, Khloud Abdo Soliman Elsharawy
Funding agency: Instituto de Salud Carlos III
Funding: 315000
Reference: PI23/01144
Duration: 01/01/2024 - 31/12/2026

Unveiling the role of chromatin remodelers in pediatric tumors of the central nervous system.

IP: Miguel Segura Ginard
Collaborators: Khloud Abdo Soliman Elsharawy , Unveiling the role of chromatin remodelers in pediatric tumors of the central nervous system.
Funding agency: Instituto de Salud Carlos III
Funding: 95000
Reference: CD23/00035
Duration: 01/01/2024 - 31/12/2026

IMPACT- AML

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Núria Torquet i Luna, Núria Torquet i Luna, Esther García Pagès, Esther García Pagès, Ángela Menárguez López, Ángela Menárguez López, Clara Durlach, Clara Durlach, Daiana Natali Lopez
Funding agency: EUROPEAN COMMISSION
Funding: 244375
Reference: IMPACT-AML_M.MAÑU_HE_2022
Duration: 01/04/2023 - 31/03/2028

SYNTHEMA: Synthetic generation of hematological data over federated computing frameworks

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Anna Collado Gimbert, Ángela Menárguez López, Claire Diot, Amira Idrizovic
Funding agency: EUROPEAN COMMISSION
Funding: 435937.5
Reference: SYNTHEMA_M.MAÑU_HE_2022
Duration: 01/12/2022 - 30/11/2026

Blog

News

The projects, selected under the 2026 Health Research and CaixaImpulse Health Innovation calls, address topics ranging from new therapies for childhood neurological disorders and Parkinson’s disease to the treatment of mitochondrial diseases and cancer.

A new publication describes the creation of this initiative, which has facilitated access to genomic studies for more than 900 pediatric patients with cancer from across Spain.

The families of the professionals had the opportunity to visit the facilities and discover how we work at the institution.