About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 37945711 Journal: Scientific Reports Year: 2023 Reference: Sci Rep. 2023 Nov 9;13(1):19552. doi: 10.1038/s41598-023-46628-5. Impact factor: Publication type: Paper in international publication Authors: Abdelhak, Ahmed; Alvarez-Lafuente, Roberto; Areny, A; Arevalo, J; Bachhuber, Franziska; Benkert, Pascal; Berek, Klaus; Blanco, Yolanda; Campoy, I; Cantero-Recasens, G et al. DOI: 10.1038/s41598-023-46628-5
PMID: 37967488 Journal: Annals of Physical and Rehabilitation Medicine Year: 2023 Reference: Ann Phys Rehabil Med. 2023 Nov 13;66(7):101798. doi: 10.1016/j.rehab.2023.101798. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Arntzen, Ellen Christin; Coote, Susan; de Oliveira, Ricardo Kaempf; Jonsdottir, Johanna; Kalron, Alon; Kos, Daphne; Learmonth, Yvonne C; Moumdjian, Lousin; Nedeljkovic, Una; Novotna, Klara et al. DOI: 10.1016/j.rehab.2023.101798
PMID: 37978852 Journal: Multiple Sclerosis Journal Year: 2023 Reference: Mult Scler. 2023 Nov 18:13524585231205962. doi: 10.1177/13524585231205962. Impact factor: Publication type: Paper in international publication Authors: Acosta-Herrera, Marialbert; Alexandri, Nektaria; Brieva, Luis; Brochet, Bruno; Callejas, Jose L; Guillen-Del-Castillo, Alfredo; Hupperts, Raymond; Keller, Birgit; Kubala Havrdova, Eva; Langdon, Dawn et al. DOI: 10.1177/13524585231205962
PMID: 37979966 Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Year: 2023 Reference: J Neurol Neurosurg Psychiatry. 2023 Nov 18:jnnp-2023-332542. doi: 10.1136/jnnp-2023-332542. Impact factor: Publication type: Paper in international publication Authors: Abdel-Mannan, Omar; Barrabes, Jose A; Champsas, Dimitrios; Chitre, Manali; Ciccarelli, Olga; Desai, Ishita; Forsyth, Rob; Hacohen, Yael; Hemingway, Cheryl; Kneen, Rachel et al. DOI: 10.1136/jnnp-2023-332542
PMID: 34850641 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):16-28. doi: 10.1177/13524585211059766. Epub 2021 Dec 1. Impact factor: Publication type: Paper in international publication Authors: Carroll, William; Ciccarelli, Olga; Coetzee, Timothy; Comi, Giancarlo; Cross, Anne; Donnelly, Alexis; Feinstein, Anthony; Fox, Robert J; Helme, Anne; Hohlfeld, Reinhard et al. DOI: 10.1177/13524585211059766
PMID: 34720200 Journal: PATTERN RECOGNITION Year: 2022 Reference: Pattern Recognit. 2022 Mar;123:108403. doi: 10.1016/j.patcog.2021.108403. Epub 2021 Oct 26. Impact factor: Publication type: Paper in international publication Authors: Bailon, Raquel; Buron, Mathias; Comi, Giancarlo; Conde, Pauline; Consortium, Radar-Cns; Costa, Gloria Dalla; Cummins, Nicholas; Dineley, Judith; Dobson, Richard Jb; Folarin, Amos A et al. DOI: 10.1016/j.patcog.2021.108403
PMID: 34859704 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jul;28(8):1209-1218. doi: 10.1177/13524585211061339. Epub 2021 Dec 3. Impact factor: Publication type: Paper in international publication Authors: Alonso, Juli; Auger, Cristina; Aymerich, Francesc Xavier; Corral, Juan Francisco; de Barros, Andrea; Llado, Xavier; Montalban, Xavier; Ng Wong, Yiken Karelys; Oliver, Arnau; Pareto, Deborah et al. DOI: 10.1177/13524585211061339
PMID: 36605095 Journal: Frontiers in rehabilitation sciences Year: 2022 Reference: Front Rehabil Sci. 2022 Dec 20;3:1006699. doi: 10.3389/fresc.2022.1006699. eCollection 2022. Impact factor: Publication type: Paper in international publication Authors: Anglada, Elisenda; Aparicio-Mingueza, Ana; Arevalo, Maria Jesus; Arrabal-Gomez, Carlos; Balaguer-Marmana, Marta; Borges, Monica; Conde, Cristina; Garcia-Vaz, Fabiola; Gich-Fulla, Jordi; Gil-Sanchez, Anna et al. DOI: 10.3389/fresc.2022.1006699
PMID: 34421797 Journal: Frontiers in Neurology Year: 2021 Reference: Front Neurol. 2021 Aug 4;12:693333. doi: 10.3389/fneur.2021.693333. eCollection 2021. Impact factor: 4.003 Publication type: Paper in international publication Authors: Gandini Wheeler-Kingshott, Claudia A M, Kappos, Ludwig, Rocca, Maria A, Filippi, Massimo, Yiannakas, Marios, Barkhof, Frederik, Vrenken, Hugo, Sastre-Garriga, Jaume, Rovira, Alex, Brouwer, Iman et al. DOI: 10.3389/fneur.2021.693333
PMID: 34418402 Journal: LANCET NEUROLOGY Year: 2021 Reference: Lancet Neurol. 2021 Sep;20(9):762-772. doi: 10.1016/S1474-4422(21)00218-0. Impact factor: 44.182 Publication type: Review in international publication Authors: Linington, Christopher, Meinl, Edgar, Palace, Jacqueline, Paul, Friedemann, Petzold, Axel, Pittock, Sean, Reindl, Markus, Sato, Douglas Kazutoshi, Selmaj, Krzysztof, Siva, Aksel et al. DOI: 10.1016/S1474-4422(21)00218-0
PMID: 34400655 Journal: Scientific Data Year: 2021 Reference: Sci Data. 2021 Aug 16;8(1):219. doi: 10.1038/s41597-021-00941-8. Impact factor: 6.444 Publication type: Paper in international publication Authors: Lagana, Maria Marcella, Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Gros, Charley, Grussu, Francesco, Hagiwara, Akifumi, Henry, Pierre-Gilles et al. DOI: 10.1038/s41597-021-00941-8
PMID: 34400839 Journal: Nature protocols Year: 2021 Reference: Nat Protoc. 2021 Oct;16(10):4611-4632. doi: 10.1038/s41596-021-00588-0. Epub 2021 Aug 16. Impact factor: 0 Publication type: Review in international publication Authors: Kinany, Nawal, Freund, Patrick, Finsterbusch, Jurgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Wheeler-Kingshott, Claudia A M Gandini, Germani, Giancarlo, Gilbert, Guillaume, Giove, Federico et al. DOI: 10.1038/s41596-021-00588-0
PMID: 31915118 Journal: Multiple Sclerosis and Related Disorders Year: 2020 Reference: Multiple Sclerosis and Related Disorders. 2020 Apr;39:101879. Impact factor: 2.889 Publication type: Paper in international publication Authors: Kos, Daphne, Ferdinand, Sofie, Duportail, Marijke, Eijssen, Isaline, Schouteden, Sofie, Kerkhofs, Lore, Jansa, Jelka, Fillo, Núria, Matuska, Kathleen, Beckerman, Heleen et al. DOI: 10.1016/j.msard.2019.101879
PMID: 33408681 Journal: Frontiers in Neurology Year: 2020 Reference: Front Neurol. 2020 Dec 17;11:579438. doi: 10.3389/fneur.2020.579438. eCollection 2020. Impact factor: 2.889 Publication type: Paper in international publication Authors: Romero, Fernando, Laroni, Alicia, Uccelli, Antonio, Perez-Sempere, Angel, Saiz, Albert, Blanco, Yolanda, Galimberti, Daniela, Scarpini, Elio, Espejo, Carmen, Montalban, Xavier et al. DOI: 10.3389/fneur.2020.579438
PMID: 32513039 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Aug;26(9):1009-1011. doi: 10.1177/1352458520926467. Epub 2020 Jun 9. Impact factor: 5.412 Publication type: Paper in international publication Authors: Solari, Alessandra, Oliver, David, Solari, Alessandra, Giordano, Andrea, Sastre-Garriga, Jaume, Kopke, Sascha, Rahn, Anne C, Kleiter, Ingo, Aleksovska, Katina, Battaglia, Mario A et al. DOI: 10.1177/1352458520926467
PMID: 33130461 Journal: JOURNAL OF NEUROIMMUNOLOGY Year: 2020 Reference: J Neuroimmunol. 2020 Dec 15;349:577425. doi: 10.1016/j.jneuroim.2020.577425. Epub 2020 Oct 17. Impact factor: 3.125 Publication type: Review in international publication Authors: Matute-Blanch, Clara, Martinez-Larrosa, Julia, Comabella, Manuel, Montalban, Xavier et al. DOI: 10.1016/j.jneuroim.2020.577425
PMID: 28301287 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Mar;24(3):301-312. doi: 10.1177/1352458517697830. Epub 2017 Mar 16. Impact factor: 5.28 Publication type: Paper in international publication Authors: Arrambide, Georgina, Rovira, Alex, Sastre-Garriga, Jaume, Tur, Carmen, Castillo, Joaquin, Rio, Jordi, Vidal-Jordana, Angela, Galan, Ingrid, Rodriguez-Acevedo, Breogan, Midaglia, Luciana et al. DOI: 10.1177/1352458517697830
PMID: 28287331 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Mar;24(3):322-330. doi: 10.1177/1352458517698052. Epub 2017 Mar 13. Impact factor: 5.28 Publication type: Paper in international publication Authors: Castillo, Joaquin, Arrambide, Georgina, Nos, Carlos, Tur, Carmen, Pujal, Berta, Auger, Cristina, Sastre-Garriga, Jaume, Montalban, Xavier, Galan, Ingrid, Vidal-Jordana, Angela et al. DOI: 10.1177/1352458517698052
PMID: 29462277 Journal: BRAIN Year: 2018 Reference: Brain. 2018 Apr 1;141(4):1075-1084. doi: 10.1093/brain/awy006. Impact factor: 10.84 Publication type: Paper in international publication Authors: Castillo, Joaquin, Vidal-Jordana, Angela, Galan, Ingrid, Nos, Carlos, Mitjana, Raquel, Mulero, Patricia, de Barros, Andrea, Rodriguez-Acevedo, Breogan, Midaglia, Luciana, Sastre-Garriga, Jaume et al. DOI: 10.1093/brain/awy006
PMID: 29452342 Journal: BRAIN Year: 2018 Reference: Brain. 2018 Apr 1;141(4):1085-1093. doi: 10.1093/brain/awy021. Impact factor: 10.84 Publication type: Paper in international publication Authors: Tintore, Mar, Sanchez, Alex, Montalban, Xavier, Comabella, Manuel, Rio, Jordi, Deisenhammer, Florian, Hegen, Harald, Quintana, Ester, Matute-Blanch, Clara, Villar, Luisa M et al. DOI: 10.1093/brain/awy021
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.