Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR.

The main lines of research are:

Complications of diabetes (in particular diabetic retinopathy)
Obesity and its co-morbidities
Type 2 diabetes and cognitive impairment
Thyroid diseases
Hospital Nutrition.

Team

Marc Velilla Cajo

Research assistant
Diabetes and Metabolism
Read more

David Sabater Martínez

Research technician
Diabetes and Metabolism
Read more

Marta García Ramírez

Senior researcher
Diabetes and Metabolism
Read more

Anna Casteras Román

Research technician
Diabetes and Metabolism
Read more

Alba Rojano Toimil

Predoctoral researcher
Diabetes and Metabolism
Read more

Alejandra Planas Vilaseca

Diabetes and Metabolism
Read more

Marc Velilla Cajo

Research assistant
Diabetes and Metabolism
Read more

David Sabater Martínez

Research technician
Diabetes and Metabolism
Read more

Marta García Ramírez

Senior researcher
Diabetes and Metabolism
Read more

Anna Casteras Román

Research technician
Diabetes and Metabolism
Read more

Alba Rojano Toimil

Predoctoral researcher
Diabetes and Metabolism
Read more

Alejandra Planas Vilaseca

Diabetes and Metabolism
Read more

Research lines

Endothelial dysfunction, dyslipideamia and cardiovascular disease in type 2 diabetes.

IP: -

Insulin resistance and obesity: new pathogenic candidates and the study of co-morbidities.

1) To identify by proteomic analysis of cerebrospinal fluid new regulators of food intake. 2) To determine the influence of SHBG/sex-steroids on fat properties and distribution and the incidence of diabetes. 3) To investigate the role of the mitochondria in obesity, insulin resistance and type 2 diabetes.

IP: -

Physiopathology of diabetic retinopathy

A new approach using integrated biological systems.This is the main area of our research.

IP: -

Projects

Beques de Formació de Personal Investigador (FPI) Identificación de los mediadores comunes a la neurodegeneracion inducida por la diabetes en retina y cerebro / Unraveling the common mediators of retinal and brain diabetes-induced neurodegeneration (U

IP: Rafael Simó Canonge
Collaborators: Anna Deàs Just, Miriam Izquierdo Sans
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 98960
Reference: PRE2020-095747
Duration: 01/09/2021 - 30/08/2025

Control de la funció de les cèl·lues beta pancreàtiques pel teixit adipós marró

IP: Josep A Villena Delgado
Collaborators: Marc Velilla Cajo, Miriam Izquierdo Sans , Judit Álvarez González
Funding agency: AGAUR
Funding: 64425.41
Reference: AGAUR/BEQUESFIPREDOC/2022/VELILLA
Duration: 01/04/2022 - 31/03/2025

Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia

IP: Rafael Simó Canonge
Collaborators: Marina Jimenez Iglesias, Mireia Turch Anguera, Cristina Hernández Pascual, Jaume Rigo Quera, Julia Vazquez de Sebastian, Queralt Martin Saladich, Helena Brosa Morros, Alejandro López Targa, Patricia Bogdanov Baruj, Gianluca Fatti , Randa Falah
Funding agency: EUROPEAN COMMISSION
Funding: 950410
Reference: RECOGNISED_H2020SC1BHC2019
Duration: 01/01/2020 - 31/12/2023

Unraveling the retinal and brain mediators of diabetes-induced neurodegeneration

IP: Rafael Simó Canonge
Collaborators: Santiago Ramon y Cajal Agüeras, Joan Montaner Villalonga, Marta García Ramírez, Mireia Turch Anguera, Lorena Ramos Pérez, Hugo Ramos Abellan
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 242000
Reference: PID2019-104225RB-I00
Duration: 01/06/2020 - 31/05/2023

Sol·licitud PFIS

IP: Cristina Hernández Pascual
Collaborators: Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 82400
Reference: FI17/00213
Duration: 31/01/2018 - 30/06/2022

ADMINISTRACION TOPICA DE AGONISTAS DEL RECEPTOR DE GLP-1: UNA NUEVA ESTRATEGIA PARA EL TRATAMIENTO DE LA RETINOPATIA DIABETICA

IP: Rafael Simó Canonge
Collaborators: Hugo Ramos Abellan, Miriam Izquierdo Sans
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 88250
Reference: BES-2017-081690
Duration: 01/07/2018 - 30/06/2022

Paper del receptor nuclear RORgamma com a mediador dels efectes de la restricció calòrica en teixit adipós

IP: Josep A Villena Delgado
Collaborators: Miriam Izquierdo Sans
Funding agency: Fundació Institut de Recerca HUVH
Funding: 47268
Reference: 2018/VHIR/VILA
Duration: 15/03/2019 - 14/03/2022

MOPEAD

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: Fundació Institut de Recerca HUVH
Funding: 47268
Reference: 2018/VHIR/ORTIZ
Duration: 01/07/2019 - 30/06/2022

Premi a la trajectòria investigadora als Hospitals de l'ICS

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Institut Català de la Salut
Funding: 5000
Reference: ICS/TRAJECTORIA.HOSP/2021/SIMÓ
Duration: 28/06/2021 - 28/06/2021

Sol·licitud PFIS

ADMINISTRACION TOPICA DE AGONISTAS DEL RECEPTOR DE GLP-1: UNA NUEVA ESTRATEGIA PARA EL TRATAMIENTO DE LA RETINOPATIA DIABETICA

Paper del receptor nuclear RORgamma com a mediador dels efectes de la restricció calòrica en teixit adipós

Sol·licitud PFIS

ADMINISTRACION TOPICA DE AGONISTAS DEL RECEPTOR DE GLP-1: UNA NUEVA ESTRATEGIA PARA EL TRATAMIENTO DE LA RETINOPATIA DIABETICA

Paper del receptor nuclear RORgamma com a mediador dels efectes de la restricció calòrica en teixit adipós

MOPEAD

Desenvolupament d'un tractament tòpic (col·liri) per a la retinopatia basat en la senyalització de la via del GLP-1

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: AGAUR
Funding: 45600
Reference: 2016 FI_B 00808
Duration: 01/03/2016 - 28/02/2019

La Diabetis com accelerador de deteriorament cognitiu i malaltia d¿ Alzheimer: abordatge integral i adherència al tractament (DIALCAT)

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 74566.35
Reference: SLT002/16/00366
Duration: 01/04/2017 - 31/12/2019

Sol·licitud PFIS

ESTUDI DE LA SUSCEPTIBILITAT GENÈTICA COM A PREDICTOR DE LA PÈRDUA DE PES I LA RESSOLUCIÓ DE LES COMORBIDITATS ASSOCIADES A L¿OBESITAT DESPRÉS DE CIRURGIA BARIÀTRICA.

IP: -
Collaborators: Andreea Ciudin Mihai, Miriam Izquierdo Sans
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 82476.49
Reference: SLT006/17/00212
Duration: 21/05/2018 - 31/12/2019

Neuroprotección en la retinopatía diabética: una nueva estrategia terapéutica

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 83900
Reference: BES-2013-064944
Duration: 07/01/2014 - 06/01/2018

Pendent de complimentar

IP: Rafael Simó Canonge
Collaborators: David Martinez Selva, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 101250
Reference: CPII14/00032
Duration: 01/02/2015 - 31/01/2018

Desenvolupament d'un tractament tòpic (col·liri) per a la retinopatia basat en la senyalització de la via del GLP-1

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: AGAUR
Funding: 45600
Reference: 2016 FI_B 00808
Duration: 01/03/2016 - 28/02/2019

Sol·licitud Río Hortega

IP: Rafael Simó Canonge
Collaborators: Olga Simó Servat, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 53732
Reference: CM16/00154
Duration: 01/01/2017 - 31/12/2018

Neuroprotección en la retinopatía diabética: una nueva estrategia terapéutica

Pendent de complimentar

Desarrollo de un tratamiento tópico (colirio) para la retinopatía diabética basado en la señalización de la vía del GLP-1 (DTS15/00151).

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 18000
Reference: INT16/00204
Duration: 01/01/2017 - 31/12/2017

Desenvolupament d'un tractament tòpic (col·liri) per a la retinopatia basat en la senyalització de la via del GLP-1

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: AGAUR
Funding: 45600
Reference: 2016 FI_B 00808
Duration: 01/03/2016 - 28/02/2019

Mecanismos moleculares que regulan la expresión de la SHBG: implicaciones en la obesidad

IP: -
Collaborators: -
Funding agency: CERCA (Centres de Recerca de Catalunya)
Funding: 1000
Reference: CERCA/PIONER/2016/SAEZ
Duration: 30/11/2016 - 30/11/2016

Neuroprotección en la retinopatía diabética: una nueva estrategia terapéutica

Pendent de complimentar

European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR). Neurodegeneration as an early event in the Pathogenesis of Diabetic Retinopathy: A multicentric, prospective, phase II-III, open randomized controlled trial to assess the e

IP: Rafael Simó Canonge
Collaborators: Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 30000
Reference: INT15/00126
Duration: 01/01/2016 - 31/12/2016

European Consortium for Risk stratification and Management of Diabetic Macular Edema (EURODIME). A multidisciplinary approach based on Systems Biology. ECoDIME

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 22500
Reference: EUIN2013-51220
Duration: 01/10/2013 - 30/09/2015

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

IP: Rafael Simó Canonge
Collaborators: David Martinez Selva, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 247050
Reference: MS08/00058
Duration: 01/02/2009 - 31/01/2015

Depósito de glucógeno en la retinopatía diabética: estudio de los factores reguladores y de los mecanismos por los que induce neurodegeneración

IP: Cristina Hernández Pascual
Collaborators: Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI11/00502
Duration: 07/09/2011 - 06/09/2015

Neuroprotección en la retinopatía diabética: una nueva estrategia terapéutica

European Consortium for Risk stratification and Management of Diabetic Macular Edema (EURODIME). A multidisciplinary approach based on Systems Biology. ECoDIME

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Depósito de glucógeno en la retinopatía diabética: estudio de los factores reguladores y de los mecanismos por los que induce neurodegeneración

Neuroprotección en la retinopatía diabética: una nueva estrategia terapéutica

European Consortium for Risk stratification and Management of Diabetic Macular Edema (EURODIME). A multidisciplinary approach based on Systems Biology. ECoDIME

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Papel del coactivador PGC-1b en tejido adiposo blanco y su contribución al desarrollo de la obseidad y la diabetes de tipo 2

IP: Josep A Villena Delgado
Collaborators: Miriam Izquierdo Sans
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 42996.39
Reference: BES-2009-013411
Duration: 01/09/2009 - 31/08/2013

Depósito de glucógeno en la retinopatía diabética: estudio de los factores reguladores y de los mecanismos por los que induce neurodegeneración

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Papel del coactivador PGC-1b en tejido adiposo blanco y su contribución al desarrollo de la obseidad y la diabetes de tipo 2

Depósito de glucógeno en la retinopatía diabética: estudio de los factores reguladores y de los mecanismos por los que induce neurodegeneración

Intensificació

IP: Cristina Hernández Pascual
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 30000
Reference: INT11/325
Duration: 01/01/2012 - 31/12/2012

Mediadors patogènics de l'edema macular diabètic: Estudi comparatiu amb la retinopatia diabética proliferativa i exploració de nous candidats mitjançant anàlisi proteòmica a l'humor vitri

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 14507.28
Reference: PRED/IR-HUVH/11/2007
Duration: 01/01/2008 - 31/10/2011

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Papel del coactivador PGC-1b en tejido adiposo blanco y su contribución al desarrollo de la obseidad y la diabetes de tipo 2

Intensificació

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 30000
Reference: INT10/331
Duration: 01/01/2011 - 31/12/2011

Mediadors patogènics de l'edema macular diabètic: Estudi comparatiu amb la retinopatia diabética proliferativa i exploració de nous candidats mitjançant anàlisi proteòmica a l'humor vitri

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 14507.28
Reference: PRED/IR-HUVH/11/2007
Duration: 01/01/2008 - 31/10/2011

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Papel del coactivador PGC-1b en tejido adiposo blanco y su contribución al desarrollo de la obseidad y la diabetes de tipo 2

Papel del coactivador PGC-1 beta en tejido adiposo blanco y su contribución al desarrollo de la obesidad y la diabetes de tipo 2

IP: Josep A Villena Delgado
Collaborators: Rosario Pardo Diaz
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 168190
Reference: SAF2008-03644
Duration: 01/01/2009 - 31/03/2012

Mediadors patogènics de l'edema macular diabètic: Estudi comparatiu amb la retinopatia diabética proliferativa i exploració de nous candidats mitjançant anàlisi proteòmica a l'humor vitri

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 14507.28
Reference: PRED/IR-HUVH/11/2007
Duration: 01/01/2008 - 31/10/2011

Sex hormone-binding globulin (SHBG): Identification of the molecular mechanisms that regulate its expression and role in body fat distribution and in the development of type 2 diabetes

Papel del coactivador PGC-1b en tejido adiposo blanco y su contribución al desarrollo de la obseidad y la diabetes de tipo 2

Mediadores patogénicos del edema macular diabético: exploración de nuevos candidatos mediante análisis proteómico en humor vítrico y cultivos celulares

IP: Rafael Simó Canonge
Collaborators: Marta García Ramírez, Àlex Fonollosa Calduch, Laura Sararols Ramsay, Cristina Hernández Pascual, Monica Higuera Urbano
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 150766
Reference: SAF2006-05284
Duration: 01/10/2006 - 30/09/2009

Hospital Universitari MAS

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: AGAUR
Funding: 11400
Reference: 2007 BE-1 10072
Duration: 10/09/2007 - 10/03/2008

Mediadors patogènics de l'edema macular diabètic: Estudi comparatiu amb la retinopatia diabética proliferativa i exploració de nous candidats mitjançant anàlisi proteòmica a l'humor vitri

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 14507.28
Reference: PRED/IR-HUVH/11/2007
Duration: 01/01/2008 - 31/10/2011

Mediadores patogénicos del edema macular diabético: exploración de nuevos candidatos mediante análisis proteómico en humor vítrico y cultivos celulares

Síndrome de apneas-hipopneas del sueño en mujeres premenopáusicas con obesidad mórbida incluidas en un programa de cirugía bariátrica. Influencia sobre los factores de riesgo cardiovascular: activación simpática, inflamación y resistencia a la insulina

IP: -
Collaborators: Odile Romero Santo-Tomas, Jose Manuel Fort López-Barajas, Gabriel Sampol Rubio
Funding agency: Instituto de Salud Carlos III
Funding: 25410
Reference: PI060476
Duration: 01/01/2007 - 30/12/2009

Hospital Universitari MAS

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: AGAUR
Funding: 11400
Reference: 2007 BE-1 10072
Duration: 10/09/2007 - 10/03/2008

Disfunción endometrial en la diabetes del anciano: influencia de los factores angiogénicos y antiangiogénicos

IP: Rafael Simó Canonge
Collaborators: Pilar Chacón Castro, Cristina Hernández Pascual
Funding agency: Instituto de Salud Carlos III
Funding: 66700
Reference: PI040680
Duration: 01/01/2005 - 28/11/2007

Mediadors patogènics de l'edema macular diabètic: estudi comparatiu amb la retinopatia diabètica proliferativa i exploració de nous candidats mitjançant anàlisi proteòmica a l'humor vitri

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Societat Catalana d'Endocrinologia i Nutrició
Funding: 5900
Reference: SCEN/1/2005
Duration: 01/07/2006 - 31/12/2007

Mediadores patogénicos del edema macular diabético: exploración de nuevos candidatos mediante análisis proteómico en humor vítreo y cultivos celulares

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Novo Nordisk Pharma SA
Funding: 6000
Reference: NORDISK/1/2006
Duration: 30/05/2006 - 31/12/2007

Factores angiogénicos, antiangiogénicos y actividad inmunológica en el humor vítreo de los pacientes con retinopatía diabética

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 13000
Reference: PRED/IR-HUVH/07/2002
Duration: 01/01/2003 - 31/12/2006

Factores angiogénicos y antiangiogénicos en la retinopatía diabética: cuantificación proteica en humos vítreo y estudio de expresión génica en retina.

IP: Rafael Simó Canonge
Collaborators: José García Arumí, Inés de Torres Ramirez, Laura Sararols Ramsay, Cristina Hernández Pascual
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 119000
Reference: SAF2003-00550
Duration: 15/12/2003 - 14/12/2006

Disfunción endometrial en la diabetes del anciano: influencia de los factores angiogénicos y antiangiogénicos

Defectos moleculares en la diabetes mellitus: terápia génica y celular.

IP: Rafael Simó Canonge
Collaborators: Pilar Chacón Castro, Antonio Carrascosa Lezcano, Diego Yeste Fernandez, Cristina Hernández Pascual
Funding agency: Instituto de Salud Carlos III
Funding: 2769.13
Reference: PI050812
Duration: 01/01/2006 - 31/12/2006

Factores angiogénicos, antiangiogénicos y actividad inmunológica en el humor vítreo de los pacientes con retinopatía diabética

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 13000
Reference: PRED/IR-HUVH/07/2002
Duration: 01/01/2003 - 31/12/2006

Factores angiogénicos y antiangiogénicos en la retinopatía diabética: cuantificación proteica en humos vítreo y estudio de expresión génica en retina.

Disfunción endometrial en la diabetes del anciano: influencia de los factores angiogénicos y antiangiogénicos

Factores angiogénicos, antiangiogénicos y actividad inmunológica en el humor vítreo de los pacientes con retinopatía diabética

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 13000
Reference: PRED/IR-HUVH/07/2002
Duration: 01/01/2003 - 31/12/2006

Factores angiogénicos y antiangiogénicos en la retinopatía diabética: cuantificación proteica en humos vítreo y estudio de expresión génica en retina.

Factores angiogénicos, antiangiogénicos y actividad inmunológica en el humor vítreo de los pacientes con retinopatía diabética

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 13000
Reference: PRED/IR-HUVH/07/2002
Duration: 01/01/2003 - 31/12/2006

Factores angiogénicos y antiangiogénicos en la retinopatía diabética: cuantificación proteica en humos vítreo y estudio de expresión génica en retina.

Efectos del tratamiento con infusión subcutánea contínua de insulina sobre el control metabólico y la calidad de vida relacionada con la salud

IP: -
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 15140
Reference: AETS_02/10047
Duration: 01/01/2003 - 31/12/2003

Virus de l´hepatitis C com factor de risc per desenvolupar una diabetes mellitus: estudi dels mecanismes etiopatogènics

IP: Cristina Hernández Pascual
Collaborators: Rafael Simó Canonge, Juan Ignacio Esteban Mur, Joan Genescà Ferrer
Funding agency: Fundació La Marató de TV3
Funding: 41036.17
Reference: TV3/992610
Duration: 01/01/2000 - 31/12/2002

Virus de l´hepatitis C com factor de risc per desenvolupar una diabetes mellitus: estudi dels mecanismes etiopatogènics

Estudio de la Expresión y las concentraciones intravítreas de VEGF, VCAM-1 e ICAM-1 en la retinopatía.

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 17225.01
Reference: 98/1270
Duration: 01/11/1998 - 01/11/1999

Estudio de la Expresión y las concentraciones intravítreas de VEGF, VCAM-1 e ICAM-1 en la retinopatía.

IP: Rafael Simó Canonge
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 17225.01
Reference: 98/1270
Duration: 01/11/1998 - 01/11/1999

Publications

Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline.

PMID: 34794851
Journal: TRENDS IN ENDOCRINOLOGY AND METABOLISM
Year: 2022
Reference: Trends Endocrinol Metab. 2022 Jan;33(1):50-71. doi: 10.1016/j.tem.2021.10.008. Epub 2021 Nov 15.
Impact factor: 12.015
Publication type: Review in international publication
Authors: Little, Karis; Llorian-Salvador, Maria; Scullion, Sarah; Hernandez, Cristina; Simo-Servat, Olga; Del Marco, Angel; Bosma, Esmeralda; Vargas-Soria, Maria; Carranza-Naval, Maria Jose; Van Bergen, Tine et al.
DOI: 10.1016/j.tem.2021.10.008

Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes.

PMID: 34169655
Journal: ACTA OPHTHALMOLOGICA
Year: 2022
Reference: Acta Ophthalmol. 2022 Mar;100(2):e539-e545. doi: 10.1111/aos.14948. Epub 2021 Jun 24.
Impact factor: 3.761
Publication type: Paper in international publication
Authors: Nilsson, Peter M; Fedotkina, Olena; Luk, Andrea; Jain, Ruchi; Prasad, Rashmi B; Shungin, Dmitry; Simo-Servat, Olga; Ozgumus, Turkuler; Cherviakova, Liubov; Khalimon, Nadiya et al.
DOI: 10.1111/aos.14948

Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial.

PMID: 35732390
Journal: BMJ Open
Year: 2022
Reference: BMJ Open. 2022 Jun 22;12(6):e060822. doi: 10.1136/bmjopen-2022-060822.
Impact factor: 2.692
Publication type: Paper in international publication
Authors: Lusilla-Palacios, Pilar; Ramos-Quiroga, Jose Antonio; Vazquez-De Sebastian, Julia; Puig, Gemma Parramon; Ciudin, Andreea; Comas, Marta; Cano Porras, Desiderio; Spanlang, Bernhard; Slater, Mel; Anastasiadou, Dimitra et al.
DOI: 10.1136/bmjopen-2022-060822

When Sugar Reaches the Liver: Phenotypes of Patients with Diabetes and NAFLD.

PMID: 35743358
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jun 8;11(12). pii: jcm11123286. doi: 10.3390/jcm11123286.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Rojano-Toimil, Alba; Rivera-Esteban, Jesus; Banares, Juan; Ciudin, Andreea; Pericas, Juan M; Ferrer, Roser; Gabriel-Medina, Pablo; Martinez Selva, David; Manzano-Nunez, Ramiro et al.
DOI: 10.3390/jcm11123286

Craniopharyngioma in the Elderly: A Multicenter and Nationwide Study in Spain.

PMID: 33040060
Journal: NEUROENDOCRINOLOGY
Year: 2021
Reference: Neuroendocrinology. 2021;111(10):925-936. doi: 10.1159/000512161. Epub 2020 Oct 9.
Impact factor: 4.914
Publication type: Paper in international publication
Authors: Iglesias, Pedro, Venegas-Moreno, Eva, Ares, Jessica, Biagetti, Betina, Rodriguez Berrocal, Victor, Guerrero-Perez, Fernando, Vicente, Almudena, Villar-Taibo, Rocio, Cordido, Fernando, Paja, Miguel et al.
DOI: 10.1159/000512161

Assessing Liver Fibrosis Using the FIB4 Index in the Community Setting.

PMID: 34943471
Journal: Diagnostics
Year: 2021
Reference: Diagnostics (Basel). 2021 Nov 29;11(12). pii: diagnostics11122236. doi: 10.3390/diagnostics11122236.
Impact factor: 3.706
Publication type: Paper in international publication
Authors: Buti, Maria, Blanco-Grau, Albert, Gabriel-Medina, Pablo, Rodriguez-Algarra, Francisco, Villena, Yolanda, Lopez-Martinez, Rosa, Augustin, Salvador, Pons, Monica, Cruz, Luz-Maria, Rando-Segura, Ariadna et al.
DOI: 10.3390/diagnostics11122236

Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy.

PMID: 34944588
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Nov 26;9(12). pii: biomedicines9121772. doi: 10.3390/biomedicines9121772.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Ramos, Hugo, Bogdanov, Patricia, Sabater, David, Huerta, Jordi, Valeri, Marta, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.3390/biomedicines9121772

Diabetic Retinopathy and Skin Tissue Advanced Glycation End Products Are Biomarkers of Cardiovascular Events in Type 2 Diabetic Patients.

PMID: 34945815
Journal: Journal of Personalized Medicine
Year: 2021
Reference: J Pers Med. 2021 Dec 10;11(12). pii: jpm11121344. doi: 10.3390/jpm11121344.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Planas, Alejandra, Simo-Servat, Olga, Hernandez, Cristina, Ortiz-Zuniga, Angel, Marsal, Joan Ramon, Herance, Jose R, Ferreira-Gonzalez, Ignacio, Simo, Rafael et al.
DOI: 10.3390/jpm11121344

Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress.

PMID: 32927585
Journal: Antioxidants
Year: 2020
Reference: Antioxidants (Basel). 2020 Sep 10;9(9). pii: antiox9090846. doi: 10.3390/antiox9090846.
Impact factor: 5.014
Publication type: Paper in international publication
Authors: Ramos, Hugo, Bogdanov, Patricia, Sampedro, Joel, Huerta, Jordi, Simo, Rafael, Hernandez, Cristina et al.
DOI: 10.3390/antiox9090846

Clinical Applicability of the Specific Risk Score of Dementia in Type 2 Diabetes in the Identification of Patients with Early Cognitive Impairment: Results of the MOPEAD Study in Spain.

PMID: 32847012
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Aug 24;9(9). pii: jcm9092726. doi: 10.3390/jcm9092726.
Impact factor: 3.303
Publication type: Paper in international publication
Authors: Ortiz Zuniga, Angel Michael, Simo, Rafael, Rodriguez-Gomez, Octavio, Hernandez, Cristina, Rodrigo, Adrian, Jamilis, Laura, Campo, Laura, Alegret, Montserrat, Boada, Merce, Ciudin, Andreea et al.
DOI: 10.3390/jcm9092726

Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes.

PMID: 32784955
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Aug 10;9(8). pii: jcm9082579. doi: 10.3390/jcm9082579.
Impact factor: 3.303
Publication type: Paper in international publication
Authors: Arroba, Ana I, Bogdanov, Patricia, Ramos, Hugo, Simo-Servat, Olga, Simo, Rafael, Valverde, Angela M, Hernandez, Cristina et al.
DOI: 10.3390/jcm9082579

Caffeine Upregulates Hepatic Sex Hormone-Binding Globulin Production by Increasing Adiponectin Through AKT/FOXO1 Pathway in White Adipose Tissue.

PMID: 32652892
Journal: MOLECULAR NUTRITION & FOOD RESEARCH
Year: 2020
Reference: Mol Nutr Food Res. 2020 Sep;64(17):e1901253. doi: 10.1002/mnfr.201901253. Epub 2020 Jul 23.
Impact factor: 5.309
Publication type: Paper in international publication
Authors: Brianso-Llort, Laura, Fuertes-Rioja, Lidia, Ramos-Perez, Lorena, Hernandez, Cristina, Simo, Rafael, Selva, David M et al.
DOI: 10.1002/mnfr.201901253

Diabetic retinopathy as an independent predictor of subclinical cardiovascular disease: baseline results of the PRECISED study.

PMID: 31908800
Journal: BMJ Open Diabetes Research & Care
Year: 2019
Reference: BMJ Open Diabetes Res Care. 2019 Dec 29;7(1):e000845. doi: 10.1136/bmjdrc-2019-000845. eCollection 2019.
Impact factor: 5.067
Publication type: Paper in international publication
Authors: Simo, Rafael, Baneras, Jordi, Hernandez, Cristina, Rodriguez-Palomares, Jose, Valente, Filipa, Gutierrez, Laura, Gonzalez-Alujas, Teresa, Ferreira, Ignacio, Aguade-Bruix, Santiago, Seron, Daniel et al.
DOI: 10.1136/bmjdrc-2019-000845

Retinal Microperimetry: A Useful Tool for Detecting Insulin Resistance-Related Cognitive Impairment in Morbid Obesity.

PMID: 31835729
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Dec 11;8(12). pii: jcm8122181. doi: 10.3390/jcm8122181.
Impact factor: 5.688
Publication type: Paper in international publication
Authors: Ciudin, Andreea, Ortiz, Angel Michael, Fidilio, Enzamaria, Romero, Diana, Sanchez, Marta, Comas, Marta, Gonzalez, Oscar, Vilallonga, Ramon, Simo-Servat, Olga, Hernandez, Cristina et al.
DOI: 10.3390/jcm8122181

Correction to: Prevalence and risk factors for hypoparathyroidism following total thyroidectomy in Spain: a multicentric and nation-wide retrospective analysis.

PMID: 31641934
Journal: ENDOCRINE
Year: 2019
Reference: Endocrine. 2019 Nov;66(2):416. doi: 10.1007/s12020-019-02108-3.
Impact factor: 3.296
Publication type: Letter or abstract
Authors: Paja, Miguel, Sambo, Marcel, Santiago Fernandez, Piedad, Blanco Carrera, Concepcion, Galofre, Juan Carlos, Navarro, Elena, Zafon, Carles, Sanz, Eva, Oleaga, Amelia, Bandres, Orosia et al.
DOI: 10.1007/s12020-019-02108-3

Metabolic Fingerprint of Acromegaly and its Potential Usefulness in Clinical Practice.

PMID: 31561638
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Sep 26;8(10). pii: jcm8101549. doi: 10.3390/jcm8101549.
Impact factor: 5.688
Publication type: Paper in international publication
Authors: Biagetti, Betina, Herance, J R, Ferrer, Roser, Aulinas, Anna, Palomino-Schatzlein, Martina, Mesa, Jordi, Castano, J P, Luque, Raul M, Simo, Rafael et al.
DOI: 10.3390/jcm8101549

Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes.

PMID: 30428543
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Nov 13;19(11). pii: ijms19113578. doi: 10.3390/ijms19113578.
Impact factor: 3.687
Publication type: Paper in international publication
Authors: Ramos, Hugo, Guerrero, Marta, Sune-Negre, Josep Maria, Tico, Josep Ramon, Montoro, Bruno, Duran, Vicente, Arias, Luis, Hernandez, Cristina, Simo, Rafael, Garcia-Ramirez, Marta et al.
DOI: 10.3390/ijms19113578

Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration.

PMID: 30127248
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Aug 20;19(8). pii: ijms19082458. doi: 10.3390/ijms19082458.
Impact factor: 3.687
Publication type: Paper in international publication
Authors: Sampedro, Joel, Sola-Adell, Cristina, Simo-Servat, Olga, Russo, Carla, Varela-Sende, Luisa, Simo, Rafael, Hernandez, Cristina, Bogdanov, Patricia et al.
DOI: 10.3390/ijms19082458

Assessment of advanced glycation end-products as a biomarker of diabetic outcomes.

PMID: 30077632
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Nov;65(9):540-545. doi: 10.1016/j.endinu.2018.06.003. Epub 2018 Aug 2.
Impact factor: 0
Publication type: Paper in national publication
Authors: Simo-Servat, Olga, Planas, Alejandra, Ciudin, Andreea, Simo, Rafael, Hernandez, Cristina et al.
DOI: 10.1016/j.endinu.2018.06.003

Stevia rebaudiana Bertoni and Its Effects in Human Disease: Emphasizing Its Role in Inflammation, Atherosclerosis and Metabolic Syndrome.

PMID: 29995279
Journal: Current nutrition reports
Year: 2018
Reference: Current Nutrition Reports. 2018 Sep 11;7(3):161-70. doi: 10.1007/s13668-018-0228-z.
Impact factor: 0
Publication type: Review in international publication
Authors: Rojas, Joselyn, de Bravo, Mayela Cabrera, Contreras, Julio, Mantilla, Linda Pamela, Angarita, Lisse, Sepulveda, Paola Amar, Kuzmar, Isaac, Faria, Judith, Fidilio, Enzamaria, Mathew, Justin et al.
DOI: 10.1007/s13668-018-0228-z

Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma.

PMID: 27048161
Journal: Clinical & Translational Oncology
Year: 2017
Reference: Clin Transl Oncol. 2017 Jan;19(1):12-20. doi: 10.1007/s12094-016-1506-0. Epub 2016 Apr 5.
Impact factor: 2.353
Publication type: Review in international publication
Authors: Jimenez-Fonseca, P, Gomez Saez, J M, Santamaria Sandi, J, Capdevila, J, Navarro Gonzalez, E, Zafon Llopis, C, Ramon Y Cajal Asensio, T, Riesco-Eizaguirre, G, Grande, E, Galofre, J C et al.
DOI: 10.1007/s12094-016-1506-0

Cystatin-C and epicardial adipose tissue as noninvasive predictors of cardiovascular risk in acromegaly.

PMID: 27910111
Journal: CLINICAL ENDOCRINOLOGY
Year: 2017
Reference: Clin Endocrinol (Oxf). 2017 Feb;86(2):214-222. doi: 10.1111/cen.13273. Epub 2016 Dec 2.
Impact factor: 3.487
Publication type: Paper in international publication
Authors: Crespo, Iris, Aulinas, Anna, Urgell, Eulalia, Biagetti, Betina, Webb, Susan M, Valassi, Elena, Leta, Ruben, Vilades, David et al.
DOI: 10.1111/cen.13273

APLP2, RRM2 and PRC1: new putative markers for the differential diagnosis of thyroid follicular lesions.

PMID: 27796194
Journal: THYROID
Year: 2017
Reference: Thyroid. 2017 Jan;27(1):59-66. doi: 10.1089/thy.2016.0094. Epub 2016 Nov 30.
Impact factor: 3.784
Publication type: Paper in international publication
Authors: Castelblanco, Esmeralda, Zafon, Carles, Maravall, Javier, Gallel, Pilar, Martinez, Montserrat, Capel, Ismael, Bella-Cueto, Maria Rosa, Halperin, Irene, Temprana-Salvador, Jordi, Iglesias, Carmela et al.
DOI: 10.1089/thy.2016.0094

Association of HMGB1 with oxidative stress markers and regulators in PDR.

PMID: 29259392
Journal: MOLECULAR VISION
Year: 2017
Reference: Mol Vis. 2017 Dec 5;23:853-871. eCollection 2017.
Impact factor: 2.057
Publication type: Paper in international publication
Authors: De Hertogh, Gert, Opdenakker, Ghislain, Simo, Rafael, Mousa, Ahmed, Mohammad, Ghulam, Ahmad, Ajmal, Abu El-Asrar, Ahmed M, Alam, Kaiser, Garcia-Ramirez, Marta, Siddiquei, Mohammad Mairaj et al.
DOI:

[Glucose renal excretion as diabetes treatment: From an old diagnostic method to a new way of treatment].

PMID: 26823105
Journal: MEDICINA CLINICA
Year: 2016
Reference: Med Clin (Barc). 2016 May 20;146(10):460-4. doi: 10.1016/j.medcli.2015.12.003. Epub 2016 Jan 26.
Impact factor: 1.267
Publication type: Paper in national publication
Authors: Biagetti, Betina, Mesa, Jordi, Dalama, Belen et al.
DOI: 10.1016/j.medcli.2015.12.003

Two decades of growth hormone treatment in adulthood.

PMID: 26522974
Journal: Endocrinologia y Nutricion
Year: 2016
Reference: Endocrinol Nutr. 2016 Feb;63(2):55-7. doi: 10.1016/j.endonu.2015.08.004. Epub 2015 Oct 27.
Impact factor: 0
Publication type: Editorial in national publication
Authors: Mesa, Jordi, del Pozo, Carlos et al.
DOI: 10.1016/j.endonu.2015.08.004

Spanish consensus for the management of patients with advanced radioactive iodine refractory differentiated thyroid cancer.

PMID: 26601805
Journal: Endocrinologia y Nutricion
Year: 2016
Reference: Endocrinol Nutr. 2016 Apr;63(4):e17-24. doi: 10.1016/j.endonu.2015.08.007. Epub 2015 Nov 19.
Impact factor: 0
Publication type: Paper in international publication
Authors: Navarro Gonzalez, Elena, Jimenez-Fonseca, Paula, Santamaria Sandi, Javier, Gomez Saez, Jose Manuel, Capdevila, Jaume, Ramon y Cajal Asensio, Teresa, Zafon Llopis, Carles, Galofre, Juan Carlos, Riesco-Eizaguirre, Garcilaso, Grande, Enrique et al.
DOI: 10.1016/j.endonu.2015.08.007

Trends in Bariatric Surgery in Spain in the Twenty-First Century: Baseline Results and 1-Month Follow Up of the RICIBA, a National Registry.

PMID: 26661106
Journal: OBESITY SURGERY
Year: 2016
Reference: Obes Surg. 2016 Aug;26(8):1836-42. doi: 10.1007/s11695-015-2001-3.
Impact factor: 3.346
Publication type: Paper in international publication
Authors: Campos, Cristina, Masmiquel, Lluis, Tinahones, Francisco, Pujante, Pedro, Garcia-Luna, Pedro P, Bueno, Marta, Camara, Rosa, Bandres, Orosia, Caixas, Assumpta, Morales, Maria Jose et al.
DOI: 10.1007/s11695-015-2001-3

Consensus on the management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI).

PMID: 25732322
Journal: Endocrinología y Nutrición
Year: 2015
Reference: Endocrinol Nutr. 2015 Apr;62(4):e37-46. doi: 10.1016/j.endonu.2015.01.005. Epub 2015 Feb 26.
Impact factor: 0
Publication type: Paper in national publication
Authors: Galofre, Juan C, Santamaria Sandi, Javier, Capdevila, Jaume, Navarro Gonzalez, Elena, Zafon Llopis, Carles, Ramon Y Cajal Asensio, Teresa, Gomez Saez, Jose Manuel, Jimenez-Fonseca, Paula, Riesco Eizaguirre, Garcilaso, Grande, Enrique et al.
DOI: 10.1016/j.endonu.2015.01.005

Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma.

PMID: 25583658
Journal: Endocrinología y Nutrición
Year: 2015
Reference: Endocrinol Nutr. 2015 Mar;62(3):e15-22. doi: 10.1016/j.endonu.2014.11.006. Epub 2015 Jan 9.
Impact factor: 0
Publication type: Paper in international publication
Authors: Gomez Saez, Jose Manuel, Jimenez-Fonseca, Paula, Santamaria Sandi, Javier, Capdevila Castillon, Jaume, Navarro Gonzalez, Elena, Zafon Llopis, Carles, Ramon Y Cajal Asensio, Teresa, Riesco Eizaguirre, Garcilaso, Grande Pulido, Enrique, Galofre Ferrater, Juan Carlos et al.
DOI: 10.1016/j.endonu.2014.11.006

Communication between primary care and physician specialist: is it improving?

PMID: 26026235
Journal: Revista de calidad asistencial : organo de la Soci
Year: 2015
Reference: Rev Calid Asist. 2015 Jul-Aug;30(4):175-81. doi: 10.1016/j.cali.2015.04.002. Epub 2015 May 27.
Impact factor: 0
Publication type: Paper in international publication
Authors: Biagetti, B, Aulinas, A, Dalama, B, Nogues, R, Zafon, C, Mesa, J et al.
DOI: 10.1016/j.cali.2015.04.002

[New insulin types in type 1 diabetes mellitus].

PMID: 25200067
Journal: MEDICINA CLINICA
Year: 2015
Reference: Med Clin (Barc). 2015 Jul 20;145(2):70-5. doi: 10.1016/j.medcli.2014.04.024. Epub 2014 Sep 4.
Impact factor: 1.417
Publication type: Review in national publication
Authors: Mesa, Jordi et al.
DOI: 10.1016/j.medcli.2014.04.024

Escape and lipodystrophy in acromegaly during pegvisomant therapy, a retrospective multicentre Spanish study.

PMID: 24612232
Journal: CLIN ENDOCRINOL
Year: 2014
Reference: Clin Endocrinol (Oxf). 2014 Dec;81(6):883-90. doi: 10.1111/cen.12440. Epub 2014 Mar 19.
Impact factor: 3.353
Publication type: Paper in international publication
Authors: Gaztambide, Sonia, Salinas, Isabel, Pozo, Carlos Del, Castells, Ignasi, Villabona, Carles, Biagetti, Betina, Webb, Susan M, Camara, Rosa, Blanco, Concepcion, Alvarez-Escola, Cristina et al.
DOI: 10.1111/cen.12440

Cushing's disease in 2012.

PMID: 24041670
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2014
Reference: Endocrinol Nutr. 2014 Feb;61(2):93-9. doi: 10.1016/j.endonu.2013.05.003. Epub 2013 Sep 14.
Impact factor: 1.881
Publication type: Review in national publication
Authors: Obiols Alfonso, Gabriel, Biagetti Biagetti, Betina, Chacon Oreja, Ana, Salvador Rodriguez, Javier et al.
DOI: 10.1016/j.endonu.2013.05.003

Past and present in abdominal surgery management for Cushing's syndrome.

PMID: 26770719
Journal: SAGE open medicine
Year: 2014
Reference: SAGE Open Med. 2014 Mar 31;2:2050312114528905. doi: 10.1177/2050312114528905. eCollection 2014.
Impact factor: 0
Publication type: Paper in international publication
Authors: Vilallonga, Ramon, Zafon, Carles, Fort, Jose Manuel, Mesa, Jordi, Armengol, Manel et al.
DOI: 10.1177/2050312114528905

Glycemic control parameters in insulin-naive patients with uncontrolled type 2 diabetes referred to endocrinologists, and degree of implementation of the national Spanish consensus for the management of hyperglycemia.

PMID: 25260336
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2014
Reference: Endocrinol Nutr. 2014 Dec;61(10):541-7. doi: 10.1016/j.endonu.2014.06.004. Epub 2014 Sep 24.
Impact factor: 0
Publication type: Paper in national publication
Authors: Casal, Florentino, Dalama, Belen, Varillas, Francisco, Villarroel, Africa, Soto, Alfonso, Barbera, Gloria, Azriel, Sharona et al.
DOI: 10.1016/j.endonu.2014.06.004

[Abnormalities of carbohydrate metabolism in acromegaly].

PMID: 24012444
Journal: MEDICINA CLINICA
Year: 2013
Reference: Med Clin (Barc). 2013 Nov 16;141(10):442-6. doi: 10.1016/j.medcli.2013.05.035. Epub 2013 Sep 6.
Impact factor: 1.399
Publication type: Paper in national publication
Authors: Biagetti, Betina, Obiols, Gabriel, Valladares, Silvia, Arnez, Lorena, Dalama, Belen, Mesa, Jordi et al.
DOI: 10.1016/j.medcli.2013.05.035

Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment?

PMID: 23758637
Journal: THYROID
Year: 2013
Reference: Thyroid. 2013 Dec;23(12):1510-3. doi: 10.1089/thy.2013.0114. Epub 2013 Sep 3.
Impact factor: 3.544
Publication type: Paper in international publication
Authors: Casteras, Anna, Zafon, Carles, Ciudin, Andreea, Mesa, Jordi et al.
DOI: 10.1089/thy.2013.0114

A comparison on insulin regimen treatment of elderly (>70 years) and younger (<70 years) type 2 diabetic patients in actual clinical practice.

PMID: 21547506
Journal: ACTA DIABETOLOGICA
Year: 2013
Reference: Acta Diabetol. 2013 Feb;50(1):33-7. doi: 10.1007/s00592-011-0289-6. Epub 2011 May 6.
Impact factor: 4.631
Publication type: Paper in international publication
Authors: Zafon, Carles, Creus, Carmen et al.
DOI: 10.1007/s00592-011-0289-6

[Positron emission tomography-computed tomography with (18)F-fluorodeoxyglucose in patients with recurrent differentiated thyroid carcinoma and negative radioiodine scan. Diagnostic performance and relation with tyroglobulin levels].

PMID: 22726673
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2013
Reference: Rev Esp Med Nucl Imagen Mol. 2013 May-Jun;32(3):146-51. doi: 10.1016/j.remn.2012.04.014. Epub 2012 Jun 21.
Impact factor: 0.863
Publication type: Paper in national publication
Authors: Aguade-Bruix, S, Mariscal Labrador, E, Garcia Burillo, A, Castell-Conesa, J, Obiols Alfonso, G, Kisiel Gonzalez, N, Barios Profitos, M, Mesa Manteca, J et al.
DOI: 10.1016/j.remn.2012.04.014

[Evolutionary endocrinology: a pending matter].

PMID: 22113050
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2012
Reference: Endocrinol Nutr. 2012 Jan;59(1):62-8. doi: 10.1016/j.endonu.2011.09.004. Epub 2011 Nov 22.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles et al.
DOI: 10.1016/j.endonu.2011.09.004

TSH-suppressive treatment in differentiated thyroid cancer. A dogma under review.

PMID: 22173058
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2012
Reference: Endocrinol Nutr. 2012 Feb;59(2):125-30. doi: 10.1016/j.endonu.2011.10.002. Epub 2011 Dec 14.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles et al.
DOI: 10.1016/j.endonu.2011.10.002

A nontargeted proteomic approach to the study of visceral and subcutaneous adipose tissue in human obesity.

PMID: 22796336
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2012
Reference: Mol Cell Endocrinol. 2012 Nov 5;363(1-2):10-9. doi: 10.1016/j.mce.2012.07.001. Epub 2012 Jul 14.
Impact factor: 4.192
Publication type: Paper in international publication
Authors: Insenser, Maria, Montes-Nieto, Rafael, Vilarrasa, Nuria, Lecube, Albert, Simo, Rafael, Vendrell, Joan, Escobar-Morreale, Hector F et al.
DOI: 10.1016/j.mce.2012.07.001

Surgically induced weight loss by gastric bypass improves non alcoholic fatty liver disease in morbid obese patients.

PMID: 23355916
Journal: World journal of hepatology
Year: 2012
Reference: World J Hepatol. 2012 Dec 27;4(12):382-8. doi: 10.4254/wjh.v4.i12.382.
Impact factor: 2.62
Publication type: Paper in international publication
Authors: Vargas, Victor, Allende, Helena, Lecube, Albert, Salcedo, Maria Teresa, Baena-Fustegueras, Juan A, Fort, Jose M, Rivero, Joaquin, Ferrer, Roser, Catalan, Roberto, Pardina, Eva et al.
DOI: 10.4254/wjh.v4.i12.382

Treatment of thyroid cancer with the new oral agents.

PMID: 21859897
Journal: ANNALS OF ONCOLOGY
Year: 2011
Reference: Ann Oncol. 2011 Oct;22(10):2343. Epub 2011 Aug 22.
Impact factor: 6.452
Publication type: Letter or abstract
Authors: Lucas-Martin, A, Menendez-Torre, E, Pereg, V, Perez-Corral, B, Santamaria, J, Riesco-Eizaguirre, G, Zafon, C, Donnay, S, Calleja, A, Escola, C A et al.
DOI: 10.1093/annonc/mdr409

Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement.

PMID: 21876749
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(8):e23366. Epub 2011 Aug 18.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Pachon, Gisela, Petriz, Jordi, Hernandez, Cristina, Simo, Rafael, Lecube, Albert et al.
DOI: 10.1371/journal.pone.0023366

Measuring Permeability in Human Retinal Epithelial Cells (ARPE-19): Implications for the Study of Diabetic Retinopathy.

PMID: 21874452
Journal: Methods in molecular biology
Year: 2011
Reference: Methods Mol Biol. 2011;763:179-94.
Impact factor:
Publication type: Letter or abstract
Authors: Garcia-Ramirez, Marta, Villarroel, Marta, Corraliza, Lidia, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1007/978-1-61779-191-8_12

Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis.

PMID: 21737365
Journal: Endocrinol Nutr
Year: 2011
Reference: Endocrinol Nutr. 2011 Aug-Sep;58(7):347-52. Epub 2011 Jul 6.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , , , , , et al.
DOI: 10.1016/j.endonu.2011.05.003

Differences in the Form of Presentation between Papillary Microcarcinomas and Papillary Carcinomas of Larger Size.

PMID: 21209704
Journal: Journal of thyroid research
Year: 2010
Reference: J Thyroid Res. 2010 Dec 14;2011:639156.
Impact factor:
Publication type: Letter or abstract
Authors: Zafon, Carles, Baena, Juan Antonio, Castellvi, Josep, Obiols, Gabriel, Monroy, Gabriela, Mesa, Jordi et al.
DOI: 10.4061/2011/639156

Iron in obesity. An ancient micronutrient for a modern disease.

PMID: 19619262
Journal: Obesity Reviews
Year: 2010
Reference: Obes Rev. 2010 Apr;11(4):322-8. Epub 2009 Jul 10.
Impact factor: 5.086
Publication type: Review in international publication
Authors: Zafon, C, Lecube, A, Simo, R et al.
DOI: 10.1111/j.1467-789X.2009.00638.x

Endoscopic Management of Drain Inclusion in the Gastric Pouch after Gastrojejunal Leakage after Laparoscopic Roux-en-Y Gastric Bypass for the Treatment of Morbid Obesity (LRYGBP).

PMID: 20634928
Journal: Diagnostic and therapeutic endoscopy
Year: 2010
Reference: Diagn Ther Endosc. 2010;2010:891345. Epub 2010 Jun 20.
Impact factor:
Publication type: Letter or abstract
Authors: Fort, Jose Manuel, Gonzalez, Oscar, Baena, Juan Antonio, Lecube, Albert, Salord, Jose, Armengol Carrasco, Manel, Armengol-Miro, Josep Ramon, Vilallonga, Ramon et al.
DOI: 10.1155/2010/891345

New pathogenic candidates for diabetic macular edema detected by proteomic analysis.

PMID: 20587712
Journal: DIABETES CARE
Year: 2010
Reference: Diabetes Care. 2010 Jul;33(7):e92.
Impact factor: 6.718
Publication type: Letter or abstract
Authors: Hernandez, Cristina, Garcia-Ramirez, Marta, Colome, Nuria, Villarroel, Marta, Corraliza, Lidia, Garcia-Pacual, Luis, Casado, Joan, Canals, Francesc, Simo, Rafael et al.
DOI: 10.2337/dc10-0232

Fat and aging: a tale of two tissues.

PMID: 20021402
Journal: Current aging science
Year: 2009
Reference: Curr Aging Sci. 2009 Jul;2(2):83-94. doi: 10.2174/1874609810902020083.
Impact factor: 0
Publication type: Paper in international publication
Authors: Zafon, Carles et al.
DOI: 10.2174/1874609810902020083

[The mitogen-activated protein kinase (MAPK) signaling pathway in papillary thyroid cancer. From the molecular bases to clinical practice].

PMID: 19627734
Journal: Endocrinol Nutr
Year: 2009
Reference: Endocrinol Nutr. 2009 Apr;56(4):176-86. doi: 10.1016/S1575-0922(09)70982-9. Epub 2009 Jun 11.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles, Obiols, Gabriel et al.
DOI: 10.1016/S1575-0922(09)70982-9

Increased expression and activity of hepatic lipase in the liver of morbidly obese adult patients in relation to lipid content.

PMID: 18972174
Journal: OBESITY SURGERY
Year: 2009
Reference: Obes Surg. 2009 Jul;19(7):894-904.
Impact factor: 2.913
Publication type: Paper in international publication
Authors: Peinado-Onsurbe, Julia, Vargas, Victor, Pardina, Eva, Baena-Fustegueras, Juan A, Catalan, Roberto, Galard, Rosa, Lecube, Albert, Fort, Jose M, Allende, Helena et al.
DOI: 10.1007/s11695-008-9739-9

Lower zinc-alpha2-glycoprotein production by adipose tissue and liver in obese patients unrelated to insulin resistance.

PMID: 19622624
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2009
Reference: J Clin Endocrinol Metab. 2009 Nov;94(11):4499-507.
Impact factor: 6.325
Publication type: Paper in international publication
Authors: Selva, David M, Lecube, Albert, Hernandez, Cristina, Baena, Juan A, Fort, Jose M, Simo, Rafael et al.
DOI: 10.1210/jc.2009-0758

Thesis

Role of nuclear receptor ROR?1 in white adipose tissue

PhD student: maria Vila Rovira
Director/s: Josep A Villena Delgado
University: Universitat Autònoma de Barcelona
Year: 2022

Biomarkers of response to bariatric surgery

PhD student: Enzamaría Fidilio Meli
Director/s: Andreea Ciudin Mihai, Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2022

Acromegalia y huella metabólica

PhD student: Betina Biagetti Biagetti
Director/s: Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2020

Desarrollo de un tratamiento tópico en colirio para la retinopatía diabética basado en el efecto neuroprotector de GLP-1

PhD student: Joel Sampedro Vida
Director/s: Rafael Simó Canonge, Cristina Hernández Pascual, Patricia Bogdanov Baruj
University: Universitat Autònoma de Barcelona
Year: 2020

Neurodegeneration and inflammation: two crucial pathogenic events in diabetic retinopathy. New experimental insights and clinical perspectives

PhD student: Olga Simó Servat
Director/s: Rafael Simó Canonge, Cristina Hernández Pascual
University: Universitat Autònoma de Barcelona
Year: 2019

Predictive biomarkers of hypercalciuria in patients with permanent postsurgical hypoparathyroidism. Clinical implications.

PhD student: Luis Maximo García Pascual
Director/s: Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2019

Efecte de la neurodegeneració de la retina en les alteracions microvasculars de la retinopatia diabètica. Estudi dels mecanismes patogènics i implicacions terapèutiques: l'exemple del dobesilat de calci

PhD student: Cristina Solà Adell
Director/s: Rafael Simó Canonge, Cristina Hernández Pascual, Patricia Bogdanov Baruj
University: Universitat Autònoma de Barcelona
Year: 2019

Prevalença de trastorns psicopatològics en l'obesitat i la Diabetis Mellitus tipus 2: Influència sobre el control metabòlic, complicacions de la Diabetis tipus 2 i resposta al tractament de l'obesitat

PhD student: Joana Nicolau Ramis
Director/s: Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2018

La sobrecàrrega bioquímica de ferro en l'atenció primària. Prevalença i relació amb l'hemocromatosi hereditària i amb l'obesitat

PhD student: Nuria Freixenet Guitart
Director/s: Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2018

Cognitive impairment as a complication of Type 2 Diabetes: Identification of new biomarkers

PhD student: Andreea Ciudin Mihai
Director/s: Rafael Simó Canonge, Cristina Hernández Pascual
University: Universitat Autònoma de Barcelona
Year: 2017

Mecanismos moleculares que regulan la expresión de la SHBG: implicaciones en la obesidad

PhD student: Cristina Sáez Lopez
Director/s: Rafael Simó Canonge
University: Universitat Autònoma de Barcelona
Year: 2016

Neurodegeneration as an early event in the pathogenesis of diabetic retinopathy: therapeutic implications

PhD student: Lidia Corraliza Marquez
Director/s: Rafael Simó Canonge, Cristina Hernández Pascual, Patricia Bogdanov Baruj
University: Universitat Autònoma de Barcelona
Year: 2016

Estudi dels mecanismes moleculars implicats en el desenvolupament de la cardiomiopatia diabètica: paper del receptor nuclear ERRgamma

PhD student: Jaime Lasheras Márquez
Director/s: Josep A Villena Delgado
University: Universitat Autònoma de Barcelona
Year: 2016

Acciones alternativas de la proteina transportadora de esteroides sexuales (SHBG/ABP) a la espermatogénesis y al cáncer de próstata.

PhD student: David Martinez Selva
Director/s: Jaume Reventós Puigjaner, Francina Munell Casadesus
University: Universitat Autònoma de Barcelona
Year: 2015

Study of the function of PGC1beta in white adipose tissue and its contribution to the development of insulin resistance

PhD student: Natàlia Enguix Elena
Director/s: Josep A Villena Delgado
University: Universitat Autònoma de Barcelona
Year: 2014

Alteraciones hidrocarbonadas en los pacientes con infección crónica por el virus de la hepatitis C: estudio de prevalencia y de los mecanismos etiopatogénicos

PhD student: Albert Lecube Torelló
Director/s:
University: Universitat Autònoma de Barcelona
Year: 2005

Blog

News

El consum de cafè podria protegir les persones amb diabetis de patir pèrdua de visió i ceguesa

Un treball on participa el Vall d'Hebron Institut de Recerca (VHIR) mostra que un consum moderat i elevat de cafeïna s'associa amb una reducció del 65% del risc de patir retinopatia diabètica en persones amb diabetis tipus 2.

Dr. Rafael Simó receives the Joaquín Barraquer Award from the Royal Academy of Medicine of Catalonia

The recognition means the admission of the current head of the Endocrinology and Nutrition Service of Vall d'Hebron University Hospital and of the Diabetes and Metabolism research group of VHIR as a member of the RAMC.

Set projectes del VHIR reben ajuts a la convocatòria de "Projectes de Generació de Coneixement" del Ministeri de Ciència i In

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Job offers

Postdoctoral Researcher - Laboratory of Metabolism and Obesity Unit of Diabetes and Metabolism

Start date:

09/03/2023

End date:

23/03/2023

Document: Download

Lab Technician Diabetes and Metabolism Research Group

Start date:

04/03/2023

End date:

18/03/2023

Document: Download

Postdoctoral Researcher - Laboratory of Metabolism and Obesity Unit of Diabetes and Metabolism

Start date:

25/01/2023

End date:

08/02/2023

Document: Download