Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR.

The main lines of research are:

Complications of diabetes (in particular diabetic retinopathy)
Obesity and its co-morbidities
Type 2 diabetes and cognitive impairment
Thyroid diseases
Hospital Nutrition.

Projects

Aquest any no hi ha projectes actius.

Publications

Prediabetes Is Associated with Increased Prevalence of Sleep-Disordered Breathing.

PMID: 35268504
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Mar 4;11(5). pii: jcm11051413. doi: 10.3390/jcm11051413.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Bermudez-Lopez, Marcelino; Castro-Boque, Eva; Dalmases, Mireia; Farras-Salles, Cristina; Fernandez, Elvira; Gavalda, Ricard; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina; Lecube, Albert et al.
DOI: 10.3390/jcm11051413

A novel case of diabetes MODY1 and chronic hereditary pancreatitis: coexistence of two infrequent genetic mutations.

PMID: 35256061
Journal: Endocrinologia Diabetes y Nutricion
Year: 2022
Reference: Endocrinol Diabetes Nutr. 2022 Feb;69(2):155-156. doi: 10.1016/j.endien.2022.02.004.
Impact factor:
Publication type: Letter or abstract
Authors: Ciudin, Andreea; Cordero-Vazquez, Efrain; Filippi-Arriaga, Francesca; Haman, Stephanie Solange Tasayco; Hernandez, Irene Hernandez et al.
DOI: 10.1016/j.endinu.2020.11.008

Macroprolactin: From laboratory to clinical practice.

PMID: 35232561
Journal: Endocrinologia Diabetes y Nutricion
Year: 2022
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Jan;69(1):63-69. doi: 10.1016/j.endien.2022.01.001. Epub 2022 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Alfayate Guerra, Rocio; Alvarez Garcia, Elias; Berlanga Escalera, Eugenio; Biagetti, Betina; Casals, Gregori; Esteban Salan, Margarita; Ferrer Costa, Roser; Garcia Lacalle, Concepcion; Gorrin Ramos, Jorge; Granada Ibern, Maria-Luisa et al.
DOI: 10.1016/j.endien.2022.01.001

Minimum Effective Dose of DPP-4 Inhibitors for Treating Early Stages of Diabetic Retinopathy in an Experimental Model.

PMID: 35203674
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 Feb 16;10(2). pii: biomedicines10020465. doi: 10.3390/biomedicines10020465.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Deas-Just, Anna; Hernandez, Cristina; Huerta, Jordi; Ramos, Hugo; Simo, Rafael; Valeri, Marta et al.
DOI: 10.3390/biomedicines10020465

Pasireotide in the Personalized Treatment of Acromegaly.

PMID: 33796079
Journal: Frontiers in Endocrinology
Year: 2021
Reference: Front Endocrinol (Lausanne). 2021 Mar 16;12:648411. doi: 10.3389/fendo.2021.648411. eCollection 2021.
Impact factor:
Publication type: Review in international publication
Authors: Aller, Javier; Alvarez-Escola, Cristina; Bernabeu, Ignacio; Biagetti, Betina; Camara, Rosa; Galvez, Maria-Angeles; Gil, Joan; Jorda, Mireia; Lamas, Cristina; Marazuela, Monica et al.
DOI: 10.3389/fendo.2021.648411

Hypoglycemia as an onset form of hypophysial infiltration by lymphoma.

PMID: 32423687
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 Apr 9;156(7):362-363. doi: 10.1016/j.medcli.2020.01.040. Epub 2020 May 16.
Impact factor:
Publication type: Letter or abstract
Authors: Cordero-Vazquez, Efrain; Mestre-Torres, Jaume; Vega-Cano, Sharela et al.
DOI: 10.1016/j.medcli.2020.01.040

HOMA-IR in acromegaly: a systematic review and meta-analysis.

PMID: 33085039
Journal: Pituitary
Year: 2021
Reference: Pituitary. 2021 Apr;24(2):146-158. doi: 10.1007/s11102-020-01092-6. Epub 2020 Oct 21.
Impact factor:
Publication type: Review in international publication
Authors: Aulinas, Anna; Biagetti, Betina; Casteras, Anna; Perez-Hoyos, Santiago; Simo, Rafael et al.
DOI: 10.1007/s11102-020-01092-6

Thyroid lobectomy in patients with differentiated thyroid cancer: an analysis of the clinical outcomes in a nationwide multicenter study.

PMID: 33708550
Journal: Gland Surgery
Year: 2021
Reference: Gland Surg. 2021 Feb;10(2):678-689. doi: 10.21037/gs-20-712.
Impact factor:
Publication type: Paper in international publication
Authors: Alcazar, Victoria; Corral, Begona Perez; Diez, Juan J; Galofre, Juan Carlos; Iglesias, Pedro; Pamplona, Maria Jose; Romero-Lluch, Ana; Sastre, Julia; Zafon, Carles et al.
DOI: 10.21037/gs-20-712

The extent of surgery for low-risk 1-4 cm papillary thyroid carcinoma: a catch-22 situation. A retrospective analysis of 497 patients based on the 2015 ATA Guidelines recommendation 35.

PMID: 32507966
Journal: ENDOCRINE
Year: 2020
Reference: Endocrine. 2020 Dec;70(3):538-543. doi: 10.1007/s12020-020-02371-9. Epub 2020 Jun 7.
Impact factor: 3.235
Publication type: Paper in international publication
Authors: Anda Apinaniz, Emma, Zafon, Carles, Ruiz Rey, Irati, Perdomo, Carolina, Pineda, Javier, Alcalde, Juan, Garcia Goni, Marta, Galofre, Juan C et al.
DOI: 10.1007/s12020-020-02371-9

Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer.

PMID: 32351680
Journal: Journal of thyroid research
Year: 2020
Reference: J Thyroid Res. 2020 Apr 14;2020:8312628. doi: 10.1155/2020/8312628. eCollection 2020.
Impact factor: 0
Publication type: Paper in international publication
Authors: Reverter, Jordi L, Rosas-Allende, Irene, Puig-Jove, Carlos, Zafon, Carles, Megia, Ana, Castells, Ignasi, Pizarro, Eduarda, Puig-Domingo, Manel, Granada, M Luisa et al.
DOI: 10.1155/2020/8312628

Diagnosis, treatment and follow-up of patients with acromegaly in a clinical practice setting in Spain: the ACROPRAXIS program Delphi survey.

PMID: 31823249
Journal: Pituitary
Year: 2020
Reference: Pituitary. 2020 Apr;23(2):129-139. doi: 10.1007/s11102-019-01012-3.
Impact factor: 3.954
Publication type: Paper in international publication
Authors: de Pablos-Velasco, Pedro, Venegas, Eva Maria, Alvarez Escola, Cristina, Fajardo, Carmen, de Miguel, Paz, Gonzalez, Natividad, Bernabeu, Ignacio, Valdes, Nuria, Paja, Miguel, Diez, Juan Jose et al.
DOI: 10.1007/s11102-019-01012-3

New Metrics to Assess Type 2 Diabetes After Bariatric Surgery: The "Time-Within-Remission Range".

PMID: 32283783
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Apr 9;9(4). pii: jcm9041070. doi: 10.3390/jcm9041070.
Impact factor: 3.303
Publication type: Paper in international publication
Authors: Lecube, Albert, Hollanda, Ana de, Lopez-Mezquita, Elena Teresa, Gils, Anna, Fidilio, Enzamaria, Bandres, Orosia, Martinez, Angel, Abuin, Jose, Marques-Pamies, Montserrat, Tuneu, Laura et al.
DOI: 10.3390/jcm9041070

Impact of an Unsolicited, Standardized Form-Based Antimicrobial Stewardship Intervention to Improve Guideline Adherence in the Management of Staphylococcus aureus Bacteremia.

PMID: 30949538
Journal: Open Forum Infectious Diseases
Year: 2019
Reference: Open Forum Infect Dis. 2019 Feb 26;6(4):ofz098. doi: 10.1093/ofid/ofz098. eCollection 2019 Apr.
Impact factor:
Publication type: Paper in international publication
Authors: Cervera, Carlos; Hernandez, Cristina; Hoang, Holly L; Lee, Mao-Cheng; Remtulla, Shahileen; Zurek, Karen et al.
DOI: 10.1093/ofid/ofz098

Paralytic Shellfish Toxins in Surf Clams Mesodesma donacium during a Large Bloom of Alexandrium catenella Dinoflagellates Associated to an Intense Shellfish Mass Mortality.

PMID: 30934869
Journal: Toxins
Year: 2019
Reference: Toxins (Basel). 2019 Mar 29;11(4):188. doi: 10.3390/toxins11040188.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Francisco; Alvarez, Gonzalo; Araya, Michael; Blanco, Juan; Diaz, Patricio A; Ganuza, Iranzu; Godoy, Marcos; Hernandez, Cristina; Pino, Roberto; Rengel, Jose et al.
DOI: 10.3390/toxins11040188

High incidence of clinically significant cytomegalovirus infection in CMV D+/R+ lung transplant recipients receiving 3 months of antiviral prophylaxis.

PMID: 30985048
Journal: Transplant Infectious Disease
Year: 2019
Reference: Transpl Infect Dis. 2019 Aug;21(4):e13094. doi: 10.1111/tid.13094. Epub 2019 Apr 29.
Impact factor:
Publication type: Paper in international publication
Authors: Cervera, Carlos; Chandrarathne, Sanjaya; Halloran, Kieran; Hernandez, Cristina; Hirji, Alim; Kabbani, Dima; Kapasi, Ali; Lien, Dale; Mabilangan, Curtis; Malhi, Harjot et al.
DOI: 10.1111/tid.13094

Emergency department and hospital crowding: causes, consequences, and cures.

PMID: 31295991
Journal:
Year: 2019
Reference: Clin Exp Emerg Med. 2019 Sep;6(3):189-195. doi: 10.15441/ceem.18.022. Epub 2019 Jul 12.
Impact factor:
Publication type: Paper in international publication
Authors: Hernandez, Cristina; Heslin, Samita M; Mallon, William K; McKenna, Peter; Morley, Eric J; Viccellio, Peter et al.
DOI: 10.15441/ceem.18.022

Cognitive impairment and dementia: a new emerging complication of type 2 diabetes-The diabetologist's perspective.

PMID: 28210868
Journal: ACTA DIABETOLOGICA
Year: 2017
Reference: Acta Diabetol. 2017 May;54(5):417-424. doi: 10.1007/s00592-017-0970-5. Epub 2017 Feb 16.
Impact factor:
Publication type: Review in international publication
Authors: Ciudin, Andreea; Hernandez, Cristina; Simo, Rafael; Simo-Servat, Olga et al.
DOI: 10.1007/s00592-017-0970-5

Development of a Normative Database for Multifocal Electroretinography in the Context of a Multicenter Clinical Trial.

PMID: 28052266
Journal: OPHTHALMIC RESEARCH
Year: 2017
Reference: Ophthalmic Res. 2017;57(2):107-117. doi: 10.1159/000450958. Epub 2017 Jan 5.
Impact factor:
Publication type: Paper in international publication
Authors: Costa, Miguel Angelo; Cunha-Vaz, Jose; Simao, Silvia; Simo, Rafael; Sun, Jennifer K et al.
DOI: 10.1159/000450958

A Standard Set of Outcome Measures for the Comprehensive Appraisal of Cleft Care.

PMID: 27223626
Journal: CLEFT PALATE-CRANIOFACIAL JOURNAL
Year: 2017
Reference: Cleft Palate Craniofac J. 2017 Sep;54(5):540-554. doi: 10.1597/15-292. Epub 2016 May 25.
Impact factor:
Publication type: Paper in international publication
Authors: Albert, Asteria; Allori, Alexander C; Bonanthaya, Krishnamurthy; Chapman, Kathy; Cunningham, Michael; Daskalogiannakis, John; de Gier, Henriette; Heggie, Andrew A; Hernandez, Cristina; Jackson, Oksana et al.
DOI: 10.1597/15-292

Effects of depressive symptoms on clinical outcomes, inflammatory markers and quality of life after a significant weight loss in a bariatric surgery sample.

PMID: 28244776
Journal: Nutricion Hospitalaria
Year: 2017
Reference: Nutr Hosp. 2017 Feb 1;34(1):81-87. doi: 10.20960/nh.979.
Impact factor:
Publication type: Paper in international publication
Authors: Ayala, Luisa; Fortuny, Regina; Masmiquel, Lluis; Nicolau, Joana; Rivera, Rosmeri; Sanchis, Pilar; Simo, Rafael et al.
DOI: 10.20960/nh.979

New Oral Hypoglycemic Agents and Cardiovascular Risk. Crossing the Metabolic Border.

PMID: 27687335
Journal: Revista espanola de cardiologia (English ed.)
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 Nov;69(11):1088-1097. doi: 10.1016/j.rec.2016.07.008. Epub 2016 Sep 26.
Impact factor: 4.596
Publication type: Review in national publication
Authors: Dalama, Belen, Mesa, Jordi et al.
DOI: 10.1016/j.rec.2016.07.008

Global Assessment of the Impact of Type 2 Diabetes on Sleep through Specific Questionnaires. A Case-Control Study.

PMID: 27315083
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jun 17;11(6):e0157579. doi: 10.1371/journal.pone.0157579. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Lecube, Albert, Sanchez, Enric, Gomez-Peralta, Fernando, Abreu, Cristina, Valls, Joan, Mestre, Olga, Romero, Odile, Martinez, Maria Dolores, Sampol, Gabriel, Ciudin, Andreea et al.
DOI: 10.1371/journal.pone.0157579

Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice.

PMID: 27267343
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Year: 2016
Reference: Biochim Biophys Acta. 2016 Sep;1862(9):1663-74. doi: 10.1016/j.bbadis.2016.05.024. Epub 2016 Jun 4.
Impact factor: 5.158
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta, Cazzoni, Daniele, de la Villa, Pedro, Sanchez-Fernandez, Elena M, Mellet, Carmen Ortiz, FGarcia Fernandez, Jose M, Hernandez, Cristina, Simo, Rafael, Valverde, Angela M, Alcalde-Estevez, Elena et al.
DOI: 10.1016/j.bbadis.2016.05.024

The placebo effect in thyroid cancer: a meta-analysis.

PMID: 26764417
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2016
Reference: Eur J Endocrinol. 2016 Apr;174(4):465-72. doi: 10.1530/EJE-15-1119. Epub 2016 Jan 13.
Impact factor: 3.892
Publication type: Paper in international publication
Authors: Guillen-Grima, Francisco, Zafon, Carles, Galofre, Juan C, Llavero-Valero, Maria et al.
DOI: 10.1530/EJE-15-1119

Effect of fenofibrate on retinal neurodegeneration in an experimental model of type 2 diabetes.

PMID: 25029994
Journal: ACTA DIABETOLOGICA
Year: 2015
Reference: Acta Diabetol. 2015 Feb;52(1):113-22. doi: 10.1007/s00592-014-0610-2. Epub 2014 Jul 17.
Impact factor: 2.399
Publication type: Paper in international publication
Authors: Bogdanov, Patricia, Hernandez, Cristina, Corraliza, Lidia, Simo, Rafael, Carvalho, Andrea R et al.
DOI: 10.1007/s00592-014-0610-2

Effect of Glycemic Control on Nocturnal Arterial Oxygen Saturation. A case-control study in Type 2 Diabetic patients.

PMID: 25043292
Journal: Journal of Diabetes
Year: 2015
Reference: J Diabetes. 2015 Jan;7(1):133-8. doi: 10.1111/1753-0407.12197. Epub 2014 Sep 10.
Impact factor: 1.932
Publication type: Paper in international publication
Authors: Lecube, Albert, Ciudin, Andreea, Sampol, Gabriel, Valladares, Silvia, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1111/1753-0407.12197

Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy.

PMID: 23335850
Journal: MOLECULAR VISION
Year: 2013
Reference: Mol Vis. 2013;19:47-53. Epub 2013 Jan 7.
Impact factor: 1.987
Publication type: Paper in international publication
Authors: Valverde, Angela M, Miranda, Soledad, Garcia-Ramirez, Marta, Gonzalez-Rodriguez, Agueda, Hernandez, Cristina, Simo, Rafael et al.
DOI:

Potential Role of Tumor Necrosis Factor-alpha in Downregulating Sex Hormone-Binding Globulin.

PMID: 22210320
Journal: DIABETES
Year: 2012
Reference: Diabetes. 2012 Feb;61(2):372-82. Epub 2011 Dec 30.
Impact factor: 8.286
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.2337/db11-0727

Molecular Mechanism of TNFalpha-Induced Down-Regulation of SHBG Expression.

PMID: 22301786
Journal: MOLECULAR ENDOCRINOLOGY
Year: 2012
Reference: Mol Endocrinol. 2012 Mar;26(3):438-46. doi: 10.1210/me.2011-1321. Epub 2012 Feb 2.
Impact factor: 4.544
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1210/me.2011-1321

Proteomic analysis of cerebrospinal fluid from obese women with idiopathic intracranial hypertension: a new approach for identifying new candidates in the pathogenesis of obesity.

PMID: 22296024
Journal: JOURNAL OF NEUROENDOCRINOLOGY
Year: 2012
Reference: J Neuroendocrinol. 2012 Jun;24(6):944-52. doi: 10.1111/j.1365-2826.2012.02288.x.
Impact factor: 3.138
Publication type: Paper in international publication
Authors: , , , , , , , , et al.
DOI: 10.1111/j.1365-2826.2012.02288.x

Diabetes is the main factor accounting for hypomagnesemia in obese subjects.

PMID: 22291997
Journal: PLoS One
Year: 2012
Reference: PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24.
Impact factor: 4.092
Publication type: Paper in international publication
Authors: Lecube, Albert, Baena-Fustegueras, Juan Antonio, Fort, Jose Manuel, Pelegri, Dolors, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1371/journal.pone.0030599

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