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Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.  

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR. 

The main lines of research are:

  • Complications of diabetes (in particular diabetic retinopathy)
  • Obesity and its co-morbidities
  • Type 2 diabetes and cognitive impairment
  • Thyroid diseases
  • Hospital Nutrition. 

Publications

When Sugar Reaches the Liver: Phenotypes of Patients with Diabetes and NAFLD.

PMID: 35743358
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jun 8;11(12). pii: jcm11123286. doi: 10.3390/jcm11123286.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Rojano-Toimil, Alba; Rivera-Esteban, Jesus; Banares, Juan; Ciudin, Andreea; Pericas, Juan M; Ferrer, Roser; Gabriel-Medina, Pablo; Martinez Selva, David; Manzano-Nunez, Ramiro et al.
DOI: 10.3390/jcm11123286

Effect of Resveratrol Content in Red Wine on Circulating Sex Hormone-Binding Globulin: Lessons from a Pilot Clinical Trial.

PMID: 35751841
Journal: MOLECULAR NUTRITION & FOOD RESEARCH
Year: 2022
Reference: Mol Nutr Food Res. 2022 Jun 25:e2200125. doi: 10.1002/mnfr.202200125.
Impact factor: 5.82
Publication type: Paper in international publication
Authors: Hernandez, Cristina; Simo, Rafael; Selva, David M; Torres-Torronteras, Javier; Ramos-Perez, Lorena; Brianso-Llort, Laura; Simo-Servat, Olga et al.
DOI: 10.1002/mnfr.202200125

Transforming growth factor-beta 1: A new factor reducing hepatic SHBG production in liver fibrosis.

PMID: 35762039
Journal: JOURNAL OF CELLULAR PHYSIOLOGY
Year: 2022
Reference: J Cell Physiol. 2022 Jun 27. doi: 10.1002/jcp.30818.
Impact factor: 6.384
Publication type: Paper in international publication
Authors: Selva, David M; Simo, Rafael; Hernandez, Cristina; Salcedo-Allende, Maria Teresa; Ramos-Perez, Lorena; Fuertes-Rioja, Lidia; Brianso-Llort, Laura et al.
DOI: 10.1002/jcp.30818

Ageing meets kidney disease.

PMID: 35768068
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Jun 30. pii: 6619640. doi: 10.1093/ndt/gfac199.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Fouque, Denis; Soler, Maria Jose; Mattace-Raso, Francesco; Ortiz, Alberto et al.
DOI: 10.1093/ndt/gfac199

Recovery of parathyroid function in patients with thyroid cancer treated by total thyroidectomy: An analysis of 685 patients with hypoparathyroidism at discharge of surgery.

PMID: 34742473
Journal: Endocrinologia Diabetes y Nutricion
Year: 2021
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2021 Jun-Jul;68(6):398-407. doi: 10.1016/j.endien.2021.10.009.
Impact factor: 1.417
Publication type: Paper in national publication
Authors: Sanz, Eva, Oleaga, Amelia, Bandres, Orosia, Donnay, Sergio, Megia, Ana, Picallo, Maria, Sanchez-Ragnarsson, Cecilia, Baena-Nieto, Gloria, Fernandez-Garcia, Jose Carlos, Lecumberri, Beatriz et al.
DOI: 10.1016/j.endien.2021.10.009

Immunotherapy-induced isolated ACTH deficiency in cancer therapy.

PMID: 34609950
Journal: ENDOCRINE-RELATED CANCER
Year: 2021
Reference: Endocr Relat Cancer. 2021 Oct 27;28(12):783-792. doi: 10.1530/ERC-21-0228.
Impact factor: 5.678
Publication type: Paper in international publication
Authors: Iglesias, Pedro, Peiro, Inmaculada, Biagetti, Betina, Paja Fano, Miguel, Cobo, Diana Ariadel, Garcia Gomez, Carlos, Mateu-Salat, Manuel, Genua, Idoia, Majem, Margarita, Riudavets, Mariona et al.
DOI: 10.1530/ERC-21-0228

Correction: Late Recovery of Parathyroid Function after Total Thyroidectomy: A Case-Control Study.

PMID: 34560785
Journal: HORMONE AND METABOLIC RESEARCH
Year: 2021
Reference: Horm Metab Res. 2021 Oct;53(10):e5. doi: 10.1055/a-1646-8410. Epub 2021 Sep 24.
Impact factor: 2.936
Publication type: Letter or abstract
Authors: Picallo, Maria, Ragnarsson, Cecilia Sanchez, Baena-Nieto, Gloria, Fernandez-Garcia, Jose Carlos, Lecumberri, Beatriz, de la Vega, Manel Sahun, Romero-Lluch, Ana R, Iglesias, Pedro, Megia, Ana, Donnay, Sergio et al.
DOI: 10.1055/a-1646-8410

Effects of the Topical Administration of Semaglutide on Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes.

PMID: 34440130
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Jul 31;9(8). pii: biomedicines9080926. doi: 10.3390/biomedicines9080926.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Simo, Rafael, Bogdanov, Patricia, Ramos, Hugo, Huerta, Jordi, Simo-Servat, Olga, Hernandez, Cristina et al.
DOI: 10.3390/biomedicines9080926

Usefulness of Eye Fixation Assessment for Identifying Type 2 Diabetic Subjects at Risk of Dementia.

PMID: 30626106
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Jan 8;8(1). pii: jcm8010059. doi: 10.3390/jcm8010059.
Impact factor: 5.688
Publication type: Paper in international publication
Authors: Simo, Rafael, Simo-Servat, Olga, Ciudin, Andreea, Ortiz-Zuniga, Angel M, Hernandez, Cristina et al.
DOI: 10.3390/jcm8010059

Sleep biosignature of Type 2 diabetes: a case-control study.

PMID: 27278263
Journal: DIABETIC MEDICINE
Year: 2017
Reference: Diabet Med. 2017 Jan;34(1):79-85. doi: 10.1111/dme.13161. Epub 2016 Jul 9.
Impact factor: 3.054
Publication type: Paper in international publication
Authors: Lecube, A, Romero, O, Sampol, G, Mestre, O, Ciudin, A, Sanchez, E, Hernandez, C, Caixas, A, Vigil, L, Simo, R et al.
DOI: 10.1111/dme.13161

LXR-dependent regulation of macrophage-specific reverse cholesterol transport is impaired in a model of genetic diabesity.

PMID: 28583767
Journal: Translational research : the journal of laboratory
Year: 2017
Reference: Transl Res. 2017 Aug;186:19-35.e5. doi: 10.1016/j.trsl.2017.05.004. Epub 2017 May 18.
Impact factor: 0
Publication type: Paper in international publication
Authors: Errico, Teresa L, Mendez-Lara, Karen Alejandra, Santos, David, Cabrerizo, Nuria, Baila-Rueda, Lucia, Metso, Jari, Cenarro, Ana, Pardina, Eva, Lecube, Albert, Jauhiainen, Matti et al.
DOI: 10.1016/j.trsl.2017.05.004

Calcium Dobesilate Prevents Neurodegeneration and Vascular Leakage in Experimental Diabetes.

PMID: 28574750
Journal: CURRENT EYE RESEARCH
Year: 2017
Reference: Curr Eye Res. 2017 Sep;42(9):1273-1286. doi: 10.1080/02713683.2017.1302591. Epub 2017 Jun 2.
Impact factor: 2.238
Publication type: Paper in international publication
Authors: Sola-Adell, Cristina, Bogdanov, Patricia, Hernandez, Cristina, Sampedro, Joel, Valeri, Marta, Garcia-Ramirez, Marta, Pasquali, Christian, Simo, Rafael et al.
DOI: 10.1080/02713683.2017.1302591

Hepatic CD36 downregulation parallels steatosis improvement in morbidly obese undergoing bariatric surgery.

PMID: 28555086
Journal: INTERNATIONAL JOURNAL OF OBESITY
Year: 2017
Reference: Int J Obes (Lond). 2017 Sep;41(9):1388-1393. doi: 10.1038/ijo.2017.115. Epub 2017 May 10.
Impact factor: 5.487
Publication type: Paper in international publication
Authors: Pardina, E, Ferrer, R, Rossell, J, Ricart-Jane, D, Mendez-Lara, K A, Baena-Fustegueras, J A, Lecube, A, Julve, J, Peinado-Onsurbe, J et al.
DOI: 10.1038/ijo.2017.115

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News

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.