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Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.  

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR. 

The main lines of research are:

  • Complications of diabetes (in particular diabetic retinopathy)
  • Obesity and its co-morbidities
  • Type 2 diabetes and cognitive impairment
  • Thyroid diseases
  • Hospital Nutrition. 

Publications

Macroprolactin: From laboratory to clinical practice.

PMID: 35232561
Journal: Endocrinologia Diabetes y Nutricion
Year: 2022
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Jan;69(1):63-69. doi: 10.1016/j.endien.2022.01.001. Epub 2022 Feb 16.
Impact factor: 1.417
Publication type: Paper in international publication
Authors: Biagetti, Betina, Ferrer Costa, Roser, Alfayate Guerra, Rocio, Alvarez Garcia, Elias, Berlanga Escalera, Eugenio, Casals, Gregori, Esteban Salan, Margarita, Granada Ibern, Maria-Luisa, Gorrin Ramos, Jorge, Lopez Lazareno, Nieves et al.
DOI: 10.1016/j.endien.2022.01.001

Minimum Effective Dose of DPP-4 Inhibitors for Treating Early Stages of Diabetic Retinopathy in an Experimental Model.

PMID: 35203674
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 Feb 16;10(2). pii: biomedicines10020465. doi: 10.3390/biomedicines10020465.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Simo, Rafael, Huerta, Jordi, Bogdanov, Patricia, Ramos, Hugo, Valeri, Marta, Deas-Just, Anna et al.
DOI: 10.3390/biomedicines10020465

Implications of Heterogeneity of Epithelial-Mesenchymal States in Acromegaly Therapeutic Pharmacologic Response.

PMID: 35203668
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 Feb 16;10(2). pii: biomedicines10020460. doi: 10.3390/biomedicines10020460.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Marques-Pamies, Montserrat, Valassi, Elena, Garcia-Martinez, Araceli, Serra, Guillermo, Hostalot, Cristina, Fajardo-Montanana, Carmen, Carrato, Cristina, Bernabeu, Ignacio, Marazuela, Monica, Rodriguez-Lloveras, Helena et al.
DOI: 10.3390/biomedicines10020460

The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up.

PMID: 34846686
Journal: OBESITY SURGERY
Year: 2022
Reference: Obes Surg. 2022 Mar;32(3):625-633. doi: 10.1007/s11695-021-05815-x. Epub 2021 Nov 30.
Impact factor: 4.129
Publication type: Paper in international publication
Authors: Ciudin, Andreea, Vila, Anna, Martinez, Marta Comas, Meli, Enzamaria Fidilio, Candia, Fiorella Palmas, Filippi, Francesca, Vilallonga, Ramon, Cordero, Efrain, Hernandez, Irene, Eguinoa, Alba Zabalegui et al.
DOI: 10.1007/s11695-021-05815-x

Thyroid lobectomy in patients with differentiated thyroid cancer: an analysis of the clinical outcomes in a nationwide multicenter study.

PMID: 33708550
Journal: Gland Surgery
Year: 2021
Reference: Gland Surg. 2021 Feb;10(2):678-689. doi: 10.21037/gs-20-712.
Impact factor: 2.953
Publication type: Paper in international publication
Authors: Diez, Juan J, Alcazar, Victoria, Iglesias, Pedro, Romero-Lluch, Ana, Sastre, Julia, Corral, Begona Perez, Zafon, Carles, Galofre, Juan Carlos, Pamplona, Maria Jose et al.
DOI: 10.21037/gs-20-712

Calorie restriction and SIRT1 overexpression induce different gene expression profiles in white adipose tissue in association with metabolic improvement.

PMID: 33686759
Journal: MOLECULAR NUTRITION & FOOD RESEARCH
Year: 2021
Reference: Mol Nutr Food Res. 2021 May;65(9):e2000672. doi: 10.1002/mnfr.202000672. Epub 2021 Mar 19.
Impact factor: 5.82
Publication type: Paper in international publication
Authors: Herrero, Laura, Cervela, Luis, Ribeiro, Marcelo L, Simo, Rafael, Villena, Josep A, Velilla, Marc, Pardo, Rosario et al.
DOI: 10.1002/mnfr.202000672

Rate of non-invasive follicular thyroid neoplasms with papillary-like nuclear features depends on pathologist's criteria: a multicentre retrospective Southern European study with prolonged follow-up.

PMID: 33484411
Journal: ENDOCRINE
Year: 2021
Reference: Endocrine. 2021 Jul;73(1):131-140. doi: 10.1007/s12020-021-02610-7. Epub 2021 Jan 23.
Impact factor: 3.633
Publication type: Paper in international publication
Authors: Anda, Emma, Povoa, Antonia, Quiceno, Hernan, Sanchez-Gomez, Nancy M, Gonzalez, Clarisa, Garcia-Pascual, Luis, Gomez de la Riva, Ines, Blanco, Concha, Meizoso, Telma, Riesco-Eizaguirre, Garcilaso et al.
DOI: 10.1007/s12020-021-02610-7

GH/IGF-1 Abnormalities and Muscle Impairment: From Basic Research to Clinical Practice.

PMID: 33401779
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Jan 2;22(1). pii: ijms22010415. doi: 10.3390/ijms22010415.
Impact factor: 5.924
Publication type: Review in international publication
Authors: Biagetti, Betina, Simo, Rafael et al.
DOI: 10.3390/ijms22010415

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News

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.