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Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.  

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR. 

The main lines of research are:

  • Complications of diabetes (in particular diabetic retinopathy)
  • Obesity and its co-morbidities
  • Type 2 diabetes and cognitive impairment
  • Thyroid diseases
  • Hospital Nutrition. 

Projects

Estudio de seguridad y eficacia de la sitagliptina en colirio para el tratamiento de los estadios iniciales de retinopatía diabética.

IP: Rafael Simó Canonge
Collaborators: Marc Rivas Agudo, Cristina Hernández Pascual, José García Arumí
Funding agency: Instituto de Salud Carlos III
Funding: 573650
Reference: ICI20/00129
Duration: 01/01/2021 - 31/10/2026

Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras MAP17 y D-AKAP-2 en ratones db/db y organoides renales humanos.

IP: Maria Jose Soler Romeo
Collaborators: Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Juan Carlos León Román, Irene Martinez Diaz
Funding agency: Instituto de Salud Carlos III
Funding: 122210
Reference: PI21/01292
Duration: 01/01/2022 - 30/06/2026

Publications

Assessment of obesity stigma and discrimination among Spanish subjects with a wide weight range: the OBESTIGMA study.

PMID: 37799531
Journal: Frontiers in Psychology
Year: 2023
Reference: Front Psychol. 2023 Sep 18;14:1209245. doi: 10.3389/fpsyg.2023.1209245. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Canizares, Silvia; Ciudin, Andreea; Ciudin, Andreea; Comas, Marta; Comas, Marta; Cuatrecasas, Guillem; Diaz-Trastoy, Olaia; Flores, Lilliam; Goni, Fernando; Gutierrez-Medina, Sonsoles et al.
DOI: 10.3389/fpsyg.2023.1209245

Efficacy of Insulin Titration Driven by SMS in Improving Glycemic Control in People with Type 2 Diabetes.

PMID: 37835008
Journal: Journal of Clinical Medicine
Year: 2023
Reference: J Clin Med. 2023 Oct 4;12(19):6364. doi: 10.3390/jcm12196364.
Impact factor:
Publication type: Paper in international publication
Authors: Amigo, Judit; Franch-Nadal, Josep; Hernandez, Cristina; Martins, Sheila Cristina Ouriques; Mayor, Regina; Molina, Carlos; Morer, Carla; Nogueira, Raul; Ortiz-Zuniga, Angel; Sanchez, Monica et al.
DOI: 10.3390/jcm12196364

Prospective Assessment of Bone Metabolism Biomarkers and Survival in Metastatic Castration-resistant Prostate Cancer Patients Treated with Radium-223: The PRORADIUM Study.

PMID: 37838555
Journal: European Urology Oncology
Year: 2023
Reference: Eur Urol Oncol. 2023 Oct 12:S2588-9311(23)00207-9. doi: 10.1016/j.euo.2023.09.015.
Impact factor:
Publication type: Paper in international publication
Authors: Almagro, Elena; Amigo, Judit; Borrega, Pablo; Castellano, Daniel C; Castro, Elena; Chirivella, Isabel; de Velasco, Guillermo; Fernandez, Ovidio; Fernandez-Freire, Ana; Fernandez-Parra, Eva et al.
DOI: 10.1016/j.euo.2023.09.015

Leptomeningeal metastasis from solid tumours: EANO-ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

PMID: 37863528
Journal: ESMO Open
Year: 2023
Reference: ESMO Open. 2023 Oct;8(5):101624. doi: 10.1016/j.esmoop.2023.101624. Epub 2023 Sep 19.
Impact factor:
Publication type: Clinical guide
Authors: Araujo-Castro, Marta; Bernabeu, Ignacio; Berrocal, Victor Rodriguez-; Biagetti, Betina; Brandsma, D; Curigliano, G; Dios, Elena; Furtner, J; Le Rhun, E; Minniti, G et al.
DOI: 10.1016/j.esmoop.2023.101624

Advanced Glycations End Products in the Skin as Biomarkers of Cardiovascular Risk in Type 2 Diabetes.

PMID: 35682915
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2022
Reference: Int J Mol Sci. 2022 Jun 2;23(11). pii: ijms23116234. doi: 10.3390/ijms23116234.
Impact factor:
Publication type: Review in international publication
Authors: Hernandez, Cristina; Planas, Alejandra; Simo, Rafael; Simo-Servat, Olga et al.
DOI: 10.3390/ijms23116234

The relationship between uric acid and brain health from observational studies.

PMID: 35670991
Journal: METABOLIC BRAIN DISEASE
Year: 2022
Reference: Metab Brain Dis. 2022 Aug;37(6):1989-2003. doi: 10.1007/s11011-022-01016-2. Epub 2022 Jun 7.
Impact factor:
Publication type: Paper in international publication
Authors: Cardoso, Marly Augusto; Simo, Rafael; Song, Zhi-Hui; Tang, Xingyao; Zhou, Jian-Bo et al.
DOI: 10.1007/s11011-022-01016-2

Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project.

PMID: 34310061
Journal: Alzheimers & Dementia
Year: 2022
Reference: Alzheimers Dement. 2022 Jun;18(6):1119-1127. doi: 10.1002/alz.12441. Epub 2021 Jul 26.
Impact factor:
Publication type: Paper in international publication
Authors: Alegret, Montserrat; Arrufat, Jordi; Belger, Mark; Boada, Merce; Campo, Laura; Ciudin, Andreea; Dumas, Annete; Georges, Jean; Glaysher, Bridget; Iradier, Fatima et al.
DOI: 10.1002/alz.12441

Intralymphatic GAD-alum (Diamyd(R)) improves glycaemic control in Type 1 diabetes with HLA DR3-DQ2.

PMID: 35665810
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2022
Reference: J Clin Endocrinol Metab. 2022 Aug 18;107(9):2644-2651. doi: 10.1210/clinem/dgac343.
Impact factor:
Publication type: Paper in international publication
Authors: Casas, Rosaura; Chavez, Lia Nattero; Clemente Leon, Maria; Dietrich, Fabricia; Gomez-Gila, Ana; Hanas, Ragnar; Hannelius, Ulf; Hernandez, Cristina; Lind, Marcus; Lozano, Marta Ferrer et al.
DOI: 10.1210/clinem/dgac343

Effects of the Topical Administration of Semaglutide on Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes.

PMID: 34440130
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Jul 31;9(8). pii: biomedicines9080926. doi: 10.3390/biomedicines9080926.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Hernandez, Cristina; Huerta, Jordi; Ramos, Hugo; Simo, Rafael; Simo-Servat, Olga et al.
DOI: 10.3390/biomedicines9080926

Relationship Between Obesity and Structural Brain Abnormality: accumulated evidence from observational studies.

PMID: 34391946
Journal: AGEING RESEARCH REVIEWS
Year: 2021
Reference: Ageing Res Rev. 2021 Nov;71:101445. doi: 10.1016/j.arr.2021.101445. Epub 2021 Aug 12.
Impact factor:
Publication type: Review in international publication
Authors: Cardoso, Marly Augusto; Han, Min; Han, Yi-Peng; Simo, Rafael; Tang, Xingyao; Yang, Jinkui; Zhou, Jianbo et al.
DOI: 10.1016/j.arr.2021.101445

Shrinkage by the third month predicts long-term response of macroprolactinoma after cabergoline.

PMID: 34374649
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2021
Reference: Eur J Endocrinol. 2021 Sep 1;185(4):587-595. doi: 10.1530/EJE-21-0561.
Impact factor:
Publication type: Paper in international publication
Authors: Biagetti, Betina; Casteras, Anna; Cordero Asanza, Esteban; Giralt-Arnaiz, Marina; Hernandez, Irene; Martinez-Saez, Elena; Ng-Wong, Yiken Karelys; Sarria-Estrada, Silvana; Simo, Rafael et al.
DOI: 10.1530/EJE-21-0561

Cardiac-Specific Overexpression of ERRgamma in Mice Induces Severe Heart Dysfunction and Early Lethality.

PMID: 34360813
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Jul 28;22(15). pii: ijms22158047. doi: 10.3390/ijms22158047.
Impact factor:
Publication type: Paper in international publication
Authors: Lasheras, Jaime; Pardo, Rosario; Poncelas, Marcos; Ruiz-Meana, Marisol; Salvatella, Nuria; Simo, Rafael; Velilla, Marc; Villena, Josep A; Zamora, Monica et al.
DOI: 10.3390/ijms22158047

Effect of Glucose Improvement on Nocturnal Sleep Breathing Parameters in Patients with Type 2 Diabetes: The Candy Dreams Study.

PMID: 32260419
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Apr 4;9(4). pii: jcm9041022. doi: 10.3390/jcm9041022.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Campos, Angela; Carmona, Paola; Dalmases, Mireia; Gaeta, Anna Michaela; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina; Hernandez, Marta; Lecube, Albert; Lopez-Cano, Carolina et al.
DOI: 10.3390/jcm9041022

Association between retinal thickness and beta-amyloid brain accumulation in individuals with subjective cognitive decline: Fundacio ACE Healthy Brain Initiative.

PMID: 32234080
Journal: Alzheimers Research & Therapy
Year: 2020
Reference: Alzheimers Res Ther. 2020 Mar 31;12(1):37. doi: 10.1186/s13195-020-00602-9.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelnour, Carla; Aguilera, N; Alegret, Montserrat; Benaque, Alba; Berthier, M; Boada, Merce; Buendia, M; Bullich, S; Campos, F; Canabate, P et al.
DOI: 10.1186/s13195-020-00602-9

Enhancing Glycolysis Protects against Ischemia-Reperfusion Injury by Reducing ROS Production.

PMID: 32235559
Journal: Metabolites
Year: 2020
Reference: Metabolites. 2020 Mar 30;10(4). pii: metabo10040132. doi: 10.3390/metabo10040132.
Impact factor:
Publication type: Paper in international publication
Authors: Barba, Ignasi; Beltran, Claudia; Bou-Teen, Diana; Ferreira-Gonzalez, Ignacio; Pardo, Rosario; Ruiz-Meana, Marisol; Villena, Josep A et al.
DOI: 10.3390/metabo10040132

Operative and Postoperative Complications of Laparoscopic Sleeve Gastrectomy in Super and Nonsuper Obese Patients: A Center of Excellence Experience Comparative Study.

PMID: 32181691
Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques
Year: 2020
Reference: J Laparoendosc Adv Surg Tech A. 2020 May;30(5):501-507. doi: 10.1089/lap.2019.0721. Epub 2020 Mar 16.
Impact factor:
Publication type: Paper in international publication
Authors: Armengol, Manel; Caubet, Enric; Ciudin, Andrea; Fort, Jose Manuel; Garcia Ruiz de Gordejuela, Amador; Gonzalez, Oscar; Hidalgo, Marta; Petrola, Carlos; Rodriguez-Luna, Maria Rita; Roriz-Silva, Renato et al.
DOI: 10.1089/lap.2019.0721

Lung function measurements in the prediabetes stage: data from the ILERVAS Project.

PMID: 30989377
Journal: ACTA DIABETOLOGICA
Year: 2019
Reference: Acta Diabetol. 2019 Sep;56(9):1005-1012. doi: 10.1007/s00592-019-01333-6. Epub 2019 Apr 15.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Benabdelhak, Ikram; Bermudez-Lopez, Marcelino; Betriu, Angels; Colas-Campas, Laura; Farras, Cristina; Fernandez, Elvira; Gaeta, Anna Michela; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina et al.
DOI: 10.1007/s00592-019-01333-6

Low survival rate and muscle fiber-dependent aging effects in the McArdle disease mouse model.

PMID: 30914683
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Mar 26;9(1):5116. doi: 10.1038/s41598-019-41414-8.
Impact factor:
Publication type: Paper in international publication
Authors: Andreu, Antoni L; Arenas, Joaquin; Brull, Astrid; de Luna, Noemi; Huerta, Jordi; Krag, Thomas O; Lucia, Alejandro; Martin, Miguel Angel; Nogales-Gadea, Gisela; Pinos, Tomas et al.
DOI: 10.1038/s41598-019-41414-8

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.

PMID: 30888539
Journal: ACTA DIABETOLOGICA
Year: 2019
Reference: Acta Diabetol. 2019 May;56(5):569-579. doi: 10.1007/s00592-019-01313-w. Epub 2019 Mar 19.
Impact factor:
Publication type: Paper in international publication
Authors: Arnoriaga-Rodriguez, Maria; Caballano-Infantes, Estefania; Coll, Claudia; Fernandez-Real, Jose Manuel; Gutierrez-Carcedo, Patricia; Herance, Jose Raul; Moreno-Navarrete, Jose Maria; Moya, Andres; Palomino-Schatzlein, Martina; Palomo-Buitrago, Maria Encarnacion et al.
DOI: 10.1007/s00592-019-01313-w

New Insights into the Mechanisms of Action of Topical Administration of GLP-1 in an Experimental Model of Diabetic Retinopathy.

PMID: 30862093
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Mar 11;8(3). pii: jcm8030339. doi: 10.3390/jcm8030339.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Hernandez, Cristina; Lagunas, Carmen; Ramos, Hugo; Sampedro, Joel; Simo, Rafael; Simo-Servat, Olga; Sola-Adell, Cristina; Turch, Mireia; Valeri, Marta et al.
DOI: 10.3390/jcm8030339

Stevia rebaudiana Bertoni and Its Effects in Human Disease: Emphasizing Its Role in Inflammation, Atherosclerosis and Metabolic Syndrome.

PMID: 29995279
Journal: Current nutrition reports
Year: 2018
Reference: Current Nutrition Reports. 2018 Sep 11;7(3):161-70. doi: 10.1007/s13668-018-0228-z.
Impact factor: 0
Publication type: Review in international publication
Authors: Rojas, Joselyn, de Bravo, Mayela Cabrera, Contreras, Julio, Mantilla, Linda Pamela, Angarita, Lisse, Sepulveda, Paola Amar, Kuzmar, Isaac, Faria, Judith, Fidilio, Enzamaria, Mathew, Justin et al.
DOI: 10.1007/s13668-018-0228-z

Barcelona Longitudinal Growth Study 1995-2017.

PMID: 29885743
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Jun - Jul;65(6):311-313. doi: 10.1016/j.endinu.2018.05.002.
Impact factor: 0
Publication type: Editorial in national publication
Authors: Carrascosa, Antonio, Mesa, Jordi et al.
DOI: 10.1016/j.endinu.2018.05.002

Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases.

PMID: 29847632
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2018
Reference: Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2264-2274. doi: 10.1167/iovs.17-23678.
Impact factor: 3.388
Publication type: Paper in international publication
Authors: Zhao, Yuanjun, Sundstrom, Jeffrey M, Hernandez, Cristina, Weber, Sarah R, Laremore, Tatiana, Simo-Servat, Olga, Garcia-Ramirez, Marta, Barber, Alistair J, Gardner, Thomas W, Simo, Rafael et al.
DOI: 10.1167/iovs.17-23678

Early evolutionary divergence between papillary and anaplastic thyroid cancers.

PMID: 29648575
Journal: ANNALS OF ONCOLOGY
Year: 2018
Reference: Ann Oncol. 2018 Jun 1;29(6):1454-1460. doi: 10.1093/annonc/mdy123.
Impact factor: 13.926
Publication type: Paper in international publication
Authors: Alvarez, C, Recio, J A, Tabernero, J, Matias-Guiu, X, Vivancos, A, Seoane, J, Cameselle-Teijeiro, J M, Nuciforo, P, Petit, A, Hernando, J et al.
DOI: 10.1093/annonc/mdy123

Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy.

PMID: 28654984
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2017
Reference: Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3189-3201. doi: 10.1167/iovs.16-20993.
Impact factor:
Publication type: Paper in international publication
Authors: Abu El-Asrar, Ahmed M; Alam, Kaiser; De Hertogh, Gert; Gouwy, Mieke; Hernandez, Cristina; Mohammad, Ghulam; Mousa, Ahmed; Opdenakker, Ghislain; Rytinx, Pieter; Siddiquei, Mohammad Mairaj et al.
DOI: 10.1167/iovs.16-20993

Sleep biosignature of Type 2 diabetes: a case-control study.

PMID: 27278263
Journal: DIABETIC MEDICINE
Year: 2017
Reference: Diabet Med. 2017 Jan;34(1):79-85. doi: 10.1111/dme.13161. Epub 2016 Jul 9.
Impact factor:
Publication type: Paper in international publication
Authors: Caixas, A; Ciudin, A; Hernandez, C; Lecube, A; Mestre, O; Romero, O; Sampol, G; Sanchez, E; Simo, R; Vigil, L et al.
DOI: 10.1111/dme.13161

Nodular Thyroid Disease and Thyroid Cancer in the Era of Precision Medicine.

PMID: 28589087
Journal: European thyroid journal
Year: 2017
Reference: Eur Thyroid J. 2017 Apr;6(2):65-74. doi: 10.1159/000457793. Epub 2017 Mar 3.
Impact factor:
Publication type: Review in national publication
Authors: Cooper, David S; Diez, Juan J; Galofre, Juan C; Zafon, Carles et al.
DOI: 10.1159/000457793

LXR-dependent regulation of macrophage-specific reverse cholesterol transport is impaired in a model of genetic diabesity.

PMID: 28583767
Journal: Translational research : the journal of laboratory
Year: 2017
Reference: Transl Res. 2017 Aug;186:19-35.e5. doi: 10.1016/j.trsl.2017.05.004. Epub 2017 May 18.
Impact factor:
Publication type: Paper in international publication
Authors: Baila-Rueda, Lucia; Blanco-Vaca, Francisco; Cabrerizo, Nuria; Cenarro, Ana; Errico, Teresa L; Escola-Gil, Joan Carles; Jauhiainen, Matti; Julve, Josep; Lecube, Albert; Mendez-Lara, Karen Alejandra et al.
DOI: 10.1016/j.trsl.2017.05.004

Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-kappaB activity.

PMID: 25936740
Journal: ACTA DIABETOLOGICA
Year: 2016
Reference: Acta Diabetol. 2016 Feb;53(1):109-18. doi: 10.1007/s00592-015-0759-3. Epub 2015 May 5.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta; Hernandez, Cristina; Palomer, Xavier; Simo, Rafael; Vazquez-Carrera, Manuel et al.
DOI: 10.1007/s00592-015-0759-3

geoRge: A Computational Tool To Detect the Presence of Stable Isotope Labeling in LC/MS-Based Untargeted Metabolomics.

PMID: 26639619
Journal: ANALYTICAL CHEMISTRY
Year: 2016
Reference: Anal Chem. 2016 Jan 5;88(1):621-8. doi: 10.1021/acs.analchem.5b03628. Epub 2015 Dec 18.
Impact factor:
Publication type: Paper in international publication
Authors: Capellades, Jordi; Garcia-Ramirez, Marta; Hernandez, Cristina; Navarro, Miriam; Samino, Sara; Simo, Rafael; Vinaixa, Maria; Yanes, Oscar et al.
DOI: 10.1021/acs.analchem.5b03628

Impact of age- and gender-specific cut-off values for the fecal immunochemical test for hemoglobin in colorectal cancer screening.

PMID: 26936343
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2016
Reference: Dig Liver Dis. 2016 May;48(5):542-551. doi: 10.1016/j.dld.2016.02.001. Epub 2016 Feb 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Urturi, Cristina; Andres, Mercedes; Andreu, Montserrat; Auge, Josep Maria; Bessa, Xavier; Bujanda, Luis; Carballo, Fernando; Castells, Antoni; Cruzado, Jose; Cubiella, Joaquin et al.
DOI: 10.1016/j.dld.2016.02.001

Evaluation of a Mixing versus a Cycling Strategy of Antibiotic Use in Critically-Ill Medical Patients: Impact on Acquisition of Resistant Microorganisms and Clinical Outcomes.

PMID: 26982807
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Mar 16;11(3):e0150274. doi: 10.1371/journal.pone.0150274. eCollection 2016.
Impact factor:
Publication type: Paper in international publication
Authors: Castro, Pedro; Cobos-Trigueros, Nazaret; De Lazzari, Elisa; Fernandez, Sara; Hernandez, Cristina; Martinez, Jose Antonio; Mensa, Josep; Morata, Laura; Nicolas, Jose Maria; Rinaudo, Mariano et al.
DOI: 10.1371/journal.pone.0150274

Effect of Glycemic Control on Nocturnal Arterial Oxygen Saturation. A case-control study in Type 2 Diabetic patients.

PMID: 25043292
Journal: J DIABETES
Year: 2015
Reference: J Diabetes. 2015 Jan;7(1):133-8. doi: 10.1111/1753-0407.12197. Epub 2014 Sep 10.
Impact factor:
Publication type: Paper in international publication
Authors: Ciudin, Andreea; Hernandez, Cristina; Lecube, Albert; Sampol, Gabriel; Simo, Rafael; Valladares, Silvia et al.
DOI: 10.1111/1753-0407.12197

Effect of fenofibrate on retinal neurodegeneration in an experimental model of type 2 diabetes.

PMID: 25029994
Journal: ACTA DIABETOL
Year: 2015
Reference: Acta Diabetol. 2015 Feb;52(1):113-22. doi: 10.1007/s00592-014-0610-2. Epub 2014 Jul 17.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Carvalho, Andrea R; Corraliza, Lidia; Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.1007/s00592-014-0610-2

Consensus on the management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI).

PMID: 25732322
Journal: Endocrinología y Nutrición
Year: 2015
Reference: Endocrinol Nutr. 2015 Apr;62(4):e37-46. doi: 10.1016/j.endonu.2015.01.005. Epub 2015 Feb 26.
Impact factor: 0
Publication type: Paper in national publication
Authors: Galofre, Juan C, Santamaria Sandi, Javier, Capdevila, Jaume, Navarro Gonzalez, Elena, Zafon Llopis, Carles, Ramon Y Cajal Asensio, Teresa, Gomez Saez, Jose Manuel, Jimenez-Fonseca, Paula, Riesco Eizaguirre, Garcilaso, Grande, Enrique et al.
DOI: 10.1016/j.endonu.2015.01.005

Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma.

PMID: 25583658
Journal: Endocrinología y Nutrición
Year: 2015
Reference: Endocrinol Nutr. 2015 Mar;62(3):e15-22. doi: 10.1016/j.endonu.2014.11.006. Epub 2015 Jan 9.
Impact factor: 0
Publication type: Paper in international publication
Authors: Gomez Saez, Jose Manuel, Jimenez-Fonseca, Paula, Santamaria Sandi, Javier, Capdevila Castillon, Jaume, Navarro Gonzalez, Elena, Zafon Llopis, Carles, Ramon Y Cajal Asensio, Teresa, Riesco Eizaguirre, Garcilaso, Grande Pulido, Enrique, Galofre Ferrater, Juan Carlos et al.
DOI: 10.1016/j.endonu.2014.11.006

Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment?

PMID: 23758637
Journal: THYROID
Year: 2013
Reference: Thyroid. 2013 Dec;23(12):1510-3. doi: 10.1089/thy.2013.0114. Epub 2013 Sep 3.
Impact factor: 3.544
Publication type: Paper in international publication
Authors: Casteras, Anna, Zafon, Carles, Ciudin, Andreea, Mesa, Jordi et al.
DOI: 10.1089/thy.2013.0114

A comparison on insulin regimen treatment of elderly (>70 years) and younger (<70 years) type 2 diabetic patients in actual clinical practice.

PMID: 21547506
Journal: ACTA DIABETOLOGICA
Year: 2013
Reference: Acta Diabetol. 2013 Feb;50(1):33-7. doi: 10.1007/s00592-011-0289-6. Epub 2011 May 6.
Impact factor: 4.631
Publication type: Paper in international publication
Authors: Zafon, Carles, Creus, Carmen et al.
DOI: 10.1007/s00592-011-0289-6

[Positron emission tomography-computed tomography with (18)F-fluorodeoxyglucose in patients with recurrent differentiated thyroid carcinoma and negative radioiodine scan. Diagnostic performance and relation with tyroglobulin levels].

PMID: 22726673
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2013
Reference: Rev Esp Med Nucl Imagen Mol. 2013 May-Jun;32(3):146-51. doi: 10.1016/j.remn.2012.04.014. Epub 2012 Jun 21.
Impact factor: 0.863
Publication type: Paper in national publication
Authors: Aguade-Bruix, S, Mariscal Labrador, E, Garcia Burillo, A, Castell-Conesa, J, Obiols Alfonso, G, Kisiel Gonzalez, N, Barios Profitos, M, Mesa Manteca, J et al.
DOI: 10.1016/j.remn.2012.04.014

Alogliptin after acute coronary syndrome in patients with type 2 diabetes.

PMID: 23992602
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2013
Reference: N Engl J Med. 2013 Oct 3;369(14):1327-35. doi: 10.1056/NEJMoa1305889. Epub 2013 Sep 2.
Impact factor: 51.658
Publication type: Paper in international publication
Authors: White, William B, Cannon, Christopher P, Heller, Simon R, Nissen, Steven E, Bergenstal, Richard M, Bakris, George L, Perez, Alfonso T, Fleck, Penny R, Mehta, Cyrus R, Kupfer, Stuart et al.
DOI: 10.1056/NEJMoa1305889

Type 2 diabetes and the lung: a bidirectional relationship.

PMID: 22265762
Journal: Endocrinol Nutr
Year: 2012
Reference: Endocrinol Nutr. 2012 Feb;59(2):95-7. doi: 10.1016/j.endonu.2011.12.003. Epub 2012 Jan 21.
Impact factor:
Publication type: Letter or abstract
Authors: ; et al.
DOI: 10.1016/j.endonu.2011.12.003

Update on Cardiovascular safety of PPARgamma agonists and relevance to medicinal chemistry and clinical pharmacology.

PMID: 22242856
Journal: CURRENT TOPICS IN MEDICINAL CHEMISTRY
Year: 2012
Reference: Curr Top Med Chem. 2012;12(6):585-604.
Impact factor:
Publication type: Review in international publication
Authors: ; ; et al.
DOI:

Preoperative thyrotropin serum concentrations gradually increase from benign thyroid nodules to papillary thyroid microcarcinomas then to papillary thyroid cancers of larger size.

PMID: 21860806
Journal: Journal of thyroid research
Year: 2012
Reference: J Thyroid Res. 2012;2012:530721. Epub 2011 Jul 19.
Impact factor:
Publication type: Letter or abstract
Authors: Baena, Juan Antonio; Castellvi, Josep; Dalama, Belen; Mesa, Jordi; Obiols, Gabriel; Zafon, Carles et al.
DOI: 10.1155/2012/530721

[Evolutionary endocrinology: a pending matter].

PMID: 22113050
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2012
Reference: Endocrinol Nutr. 2012 Jan;59(1):62-8. doi: 10.1016/j.endonu.2011.09.004. Epub 2011 Nov 22.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles et al.
DOI: 10.1016/j.endonu.2011.09.004

Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1beta by suppressing AMP-activated protein kinase (AMPK) activation.

PMID: 21369818
Journal: DIABETOLOGIA
Year: 2011
Reference: Diabetologia. 2011 Jun;54(6):1543-53. Epub 2011 Mar 3.
Impact factor: 6.973
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.1007/s00125-011-2089-5

TNF-alpha system and lung function impairment in obesity.

PMID: 21296591
Journal: CYTOKINE
Year: 2011
Reference: Cytokine. 2011 May;54(2):121-4. Epub 2011 Feb 5.
Impact factor: 3.537
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1016/j.cyto.2011.01.010

Management of patients with hernia or incisional hernia undergoing surgery for morbid obesity.

PMID: 21188167
Journal: Journal of obesity
Year: 2011
Reference: J Obes. 2011;2011:860942. Epub 2010 Dec 5.
Impact factor:
Publication type: Letter or abstract
Authors: Vilallonga, Ramon, Fort, Jose Manuel, Gonzalez, Oscar, Baena, Juan Antonio, Lecube, Albert, Armengol, Manuel et al.
DOI: 10.1155/2011/860942

Effect of intensive insulin therapy on macular biometrics, plasma VEGF and its soluble receptor in newly diagnosed diabetic patients.

PMID: 20578202
Journal: DIABETES-METABOLISM RESEARCH AND REVIEWS
Year: 2010
Reference: Diabetes Metab Res Rev. 2010 Jul;26(5):386-92.
Impact factor: 2.762
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Zapata, Miguel A, Losada, Eladio, Villarroel, Marta, Garcia-Ramirez, Marta, Garcia-Arumi, Jose, Simo, Rafael et al.
DOI: 10.1002/dmrr.1093

[Usefulness of the immunohistochemical analysis of several molecular markers in the characterization of papillary thyroid carcinoma with initial lymph node metastasis.]

PMID: 20403734
Journal: Endocrinol Nutr
Year: 2010
Reference: Endocrinol Nutr. 2010 Apr;57(4):165-9. Epub 2010 Apr 18.
Impact factor:
Publication type: Letter or abstract
Authors: , , et al.
DOI: 10.1016/j.endonu.2010.02.005

Effect of rosiglitazone on progression of coronary atherosclerosis in patients with type 2 diabetes mellitus and coronary artery disease: the assessment on the prevention of progression by rosiglitazone on atherosclerosis in diabetes patients with cardiovascular history trial.

PMID: 20194881
Journal: CIRCULATION
Year: 2010
Reference: Circulation. 2010 Mar 16;121(10):1176-87. Epub 2010 Mar 1.
Impact factor: 14.816
Publication type: Paper in international publication
Authors: Halac, Marcelo, Gerstein, Hertzel C, Ratner, Robert E, Cannon, Christopher P, Serruys, Patrick W, Garcia-Garcia, Hector M, van Es, Gerrit-Anne, Kolatkar, Nikheel S, Kravitz, Barbara G, Miller, Diane M et al.
DOI: 10.1161/CIRCULATIONAHA.109.881003

Metabolic fingerprints of proliferative diabetic retinopathy. An 1H NMR-based metabonomic approach using vitreous humor.

PMID: 20375324
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2010
Reference: Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4416-21. Epub 2010 Apr 7.
Impact factor: 3.431
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1167/iovs.10-5348

Apolipoprotein A1 is overexpressed in the retina of diabetic patients.

PMID: 18848320
Journal: AMERICAN JOURNAL OF OPHTHALMOLOGY
Year: 2009
Reference: Am J Ophthalmol. 2009 Feb;147(2):319-325.e1.
Impact factor: 3.102
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Higuera, Monica, Garcia-Ramirez, Marta, Simo, Rafael et al.
DOI: 10.1016/j.ajo.2008.08.009

Ghrelin and apolipoprotein AIV levels show opposite trends to leptin levels during weight loss in morbidly obese patients.

PMID: 19172368
Journal: OBESITY SURGERY
Year: 2009
Reference: Obes Surg. 2009 Oct;19(10):1414-23.
Impact factor: 2.913
Publication type: Paper in international publication
Authors: Baena-Fustegueras, J A, Peinado-Onsurbe, J, Fort, J M, Lecube, A, Allende, H, Pardina, E, Lopez-Tejero, M D, Llamas, R, Catalan, R, Galard, R et al.
DOI: 10.1007/s11695-008-9793-3

Lipoprotein lipase but not hormone-sensitive lipase activities achieve normality after surgically induced weight loss in morbidly obese patients.

PMID: 19455372
Journal: OBESITY SURGERY
Year: 2009
Reference: Obes Surg. 2009 Aug;19(8):1150-8.
Impact factor: 2.913
Publication type: Paper in international publication
Authors: Pardina, E, Lecube, A, Llamas, R, Catalan, R, Galard, R, Fort, J M, Allende, H, Vargas, V, Baena-Fustegueras, J A, Peinado-Onsurbe, J et al.
DOI: 10.1007/s11695-009-9853-3

Lipoprotein lipase expression in livers of morbidly obese patients could be responsible for liver steatosis.

PMID: 19301078
Journal: OBESITY SURGERY
Year: 2009
Reference: Obes Surg. 2009 May;19(5):608-16.
Impact factor: 2.913
Publication type: Paper in international publication
Authors: Pardina, Eva, Baena-Fustegueras, Juan A, Llamas, Rafael, Catalan, Roberto, Galard, Rosa, Lecube, Albert, Fort, Jose M, Llobera, Miquel, Allende, Helena, Vargas, Victor et al.
DOI: 10.1007/s11695-009-9827-5

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The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.