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General Surgery

The research group in General Surgery aims to develop research activities in the field of Surgery from the most clinical and surgical aspects related to the quality of care to the most basic and translational aspects of etiopathogenesis, pathophysiology and the bases of the diseases included in its different areas of interest, as well as in the therapeutic procedures to address them. It is focused in several topics that include the fields of Abdominal Wall Surgery, biomaterials and bioengineering, Colorectal Surgery and Proctology, General Endocrine, Bariatric and Metabolic Surgery, Esophagogastric Surgery, and Thoracic Surgery. It includes clinical surgeons who make up the care teams of the various clinical lines and includes a basic research laboratory with two researchers with special interest in the study of the extracellular matrix and inflammation and biomaterials and their integration.

Team

Carlos Alcoleba García

Carlos Alcoleba García

General Surgery
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Enric Caubet Busquet

Enric Caubet Busquet

Main researcher
General Surgery
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Esther Gil Barrionuevo

Esther Gil Barrionuevo

General Surgery
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Franco Marinello

Franco Marinello

Senior researcher
General Surgery
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Gianluca Pellino

Gianluca Pellino

Main researcher
General Surgery
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Iñigo Royo Crespo

Iñigo Royo Crespo

Senior researcher
General Surgery
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Carlos Alcoleba García

Carlos Alcoleba García

General Surgery
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Enric Caubet Busquet

Enric Caubet Busquet

Main researcher
General Surgery
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Esther Gil Barrionuevo

Esther Gil Barrionuevo

General Surgery
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Franco Marinello

Franco Marinello

Senior researcher
General Surgery
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Gianluca Pellino

Gianluca Pellino

Main researcher
General Surgery
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Iñigo Royo Crespo

Iñigo Royo Crespo

Senior researcher
General Surgery
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Publications

Management of acute diverticulitis with pericolic free gas (ADIFAS): An international multicentre observational study.

PMID: 37010145
Journal: International Journal of Surgery
Year: 2023
Reference: Int J Surg. 2023 Apr 1;109(4):689-697. doi: 10.1097/JS9.0000000000000213.
Impact factor:
Publication type: Paper in international publication
Authors: Di Saverio, Salomone; Francis, Nader; Gorter-Stam, Marguerite; Pastor, Carlos; Pellino, Gianluca; Sylla, Patricia; Tejedor, Patricia et al.
DOI: 10.1097/JS9.0000000000000213

Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection.

PMID: 37019909
Journal: Nature Communications
Year: 2023
Reference: Nat Commun. 2023 Apr 5;14(1):1887. doi: 10.1038/s41467-023-37559-w.
Impact factor:
Publication type: Paper in international publication
Authors: Buzon, Maria J; Esperalba, Juliana; Falco, Vicenc; Genesca, Meritxell; Kuguel, Sebastian G; Kuguel, Sebastian G; Mancebo, Cristina; Mancebo, Cristina; Pieren, Daan K J; Rey-Cano, Joan et al.
DOI: 10.1038/s41467-023-37559-w

Impact of the COVID-19 pandemic in the early-onset colorectal cancer.

PMID: 37031602
Journal: Translational Oncology
Year: 2023
Reference: Transl Oncol. 2023 Jun;32:101668. doi: 10.1016/j.tranon.2023.101668. Epub 2023 Apr 5.
Impact factor:
Publication type: Paper in international publication
Authors: Baraibar, Iosune; Capdevila, Jaume; Castells, Marta R; Castillo, Gloria; Comas, Raquel; Comas, Raquel; Dopazo, Cristina; Elez, Elena; Espin, Eloy; Garcia, Ariadna et al.
DOI: 10.1016/j.tranon.2023.101668

Smoking Suppresses the Therapeutic Potential of Adipose Stem Cells in Crohn's Disease Patients through Epigenetic Changes.

PMID: 37048094
Journal: Cells
Year: 2023
Reference: Cells. 2023 Mar 27;12(7):1021. doi: 10.3390/cells12071021.
Impact factor:
Publication type: Paper in international publication
Authors: Boronat-Toscano, Albert; Caro, Aleidis; Espin, Eloy; Espina, Beatriz; Manas, Maria Jose; Marti, Marc; Menacho, Margarita; Monfort-Ferre, Diandra; Saera-Vila, Alfonso; Serena, Carolina et al.
DOI: 10.3390/cells12071021

Long-term oncological outcome of segmental versus extended colectomy for colorectal cancer in Crohn's disease: results from an international multicentre study.

PMID: 34897426
Journal: Journal of Crohns & Colitis
Year: 2022
Reference: J Crohns Colitis. 2022 Jul 14;16(6):954-962. doi: 10.1093/ecco-jcc/jjab215.
Impact factor: 9.071
Publication type: Paper in international publication
Authors: Sica, Giuseppe S, Khan, Jim, Sensi, Bruno, Warusavitarne, Janindra, Nardi, Alessandra, Zaghiyan, Karen, Pellino, Gianluca, Marti-Gallostra, Marc, Frasson, Matteo, Artigue, Michael et al.
DOI: 10.1093/ecco-jcc/jjab215

Segmental versus total colectomy for Crohn's disease in the biologic era. Results from The SCOTCH international, multicentric study.

PMID: 35819368
Journal: Journal of Crohns & Colitis
Year: 2022
Reference: J Crohns Colitis. 2022 Jul 12. pii: 6640263. doi: 10.1093/ecco-jcc/jjac096.
Impact factor: 9.071
Publication type: Paper in international publication
Authors: Poggioli, Gilberto, Pellino, Gianluca, Rottoli, Matteo, Mineccia, Michela, Frontali, Alice, Celentano, Valerio, Colombo, Francesco, Baldi, Caterina, Ardizzone, Sandro, Marti Gallostra, Marc et al.
DOI: 10.1093/ecco-jcc/jjac096

Ileoanal pouch cancers in ulcerative colitis and familial adenomatous polyposis: A systematic review and meta-analysis.

PMID: 35817683
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2022
Reference: Dig Liver Dis. 2022 Jul 8. pii: S1590-8658(22)00551-5. doi: 10.1016/j.dld.2022.06.013.
Impact factor: 4.088
Publication type: Review in international publication
Authors: Sriranganathan, Danujan, Vinci, Danilo, Pellino, Gianluca, Segal, Jonathan P et al.
DOI: 10.1016/j.dld.2022.06.013

Standardization of ileoanal J-pouch surgery technique: Quality assessment of minimally invasive ileoanal J-pouch surgery videos.

PMID: 34980484
Journal: SURGERY
Year: 2022
Reference: Surgery. 2022 Jul;172(1):53-59. doi: 10.1016/j.surg.2021.11.032. Epub 2021 Dec 31.
Impact factor: 3.982
Publication type: Paper in international publication
Authors: Celentano, Valerio, Tekkis, Paris, Nordenvall, Caroline, Mills, Sarah, Spinelli, Antonino, Smart, Neil, Selvaggi, Francesco, Warren, Oliver, Espin-Basany, Eloy, Kontovounisios, Christos et al.
DOI: 10.1016/j.surg.2021.11.032

Parastomal hernia. Emergency repair.

PMID: 34312085
Journal: CIRUGIA ESPANOLA
Year: 2021
Reference: Cir Esp. 2021 Oct;99(8):619-620. doi: 10.1016/j.cireng.2020.07.016. Epub 2021 Jul 24.
Impact factor: 1.653
Publication type: Letter whit IF
Authors: Verdaguer, Mireia, Jofra, Mariona, Rodrigues, Victor, Lopez-Cano, Manuel, Rossello-Jimenez, Daniel et al.
DOI: 10.1016/j.cireng.2020.07.016

Report from 'Virtually Vilnius': the 15th Scientific and Annual Conference of the European Society of Coloproctology, 21-23 September 2020.

PMID: 34263523
Journal: Colorectal Disease
Year: 2021
Reference: Colorectal Dis. 2021 Jul;23(7):1658-1661. doi: 10.1111/codi.15632.
Impact factor: 3.788
Publication type: Letter or abstract
Authors: Pellino, Gianluca, Bellato, Vittoria, Cunha, Miguel, Gallardo, Cristian, Garoufalia, Zoe, Gujjuri, Rohan, Zaffaroni, Gloria, Brady, Richard R W et al.
DOI: 10.1111/codi.15632

Parestomal hernia repair. Prospective observational study based on the Spanish Registry of Incisional Hernia (EVEREG).

PMID: 34253496
Journal: CIRUGIA ESPANOLA
Year: 2021
Reference: Cir Esp (Engl Ed). 2021 Aug-Sep;99(7):527-534. doi: 10.1016/j.cireng.2021.06.016. Epub 2021 Jul 9.
Impact factor: 1.653
Publication type: Paper in national publication
Authors: Amador, Sara, Rodrigues-Goncalves, Victor, Verdaguer-Tremolosa, Mireia, Hernandez-Granados, Pilar, Bravo-Salva, Alejandro, Utrera Gonzalez, Antonio, Capitan Vallvey, Jose M, Pradas, Matias, Perez Gomar, Daniel, Bustos, Manuel et al.
DOI: 10.1016/j.cireng.2021.06.016

European multicenter propensity score match study of laparoscopic vs. open colectomy for splenic flexure carcinomas: Results from the Splenic Flexure Cancer (SFC) Study Group.

PMID: 34238728
Journal: Journal of Visceral Surgery
Year: 2021
Reference: J Visc Surg. 2021 Jul 5. pii: S1878-7886(21)00102-8. doi: 10.1016/j.jviscsurg.2021.06.007.
Impact factor: 2.043
Publication type: Paper in international publication
Authors: Genova, P, Sobhani, I, Stakelum, A, Gomez, S A, Torres, M T, Paya, C, Gonzalvez, P, Assalino, M, Brunetti, F, Zaborowski, A et al.
DOI: 10.1016/j.jviscsurg.2021.06.007

Preoperative oral antibiotics in colon surgery - Authors' reply.

PMID: 32818462
Journal: Lancet Gastroenterology & Hepatology
Year: 2020
Reference: Lancet Gastroenterol Hepatol. 2020 Sep;5(9):802-803. doi: 10.1016/S2468-1253(20)30241-7.
Impact factor: 14.789
Publication type: Letter or abstract
Authors: Almirante, Benito, Basany, Eloy Espin, Pellino, Gianluca et al.
DOI: 10.1016/S2468-1253(20)30241-7

Surgeons' fear of getting infected by COVID19: A global survey.

PMID: 32808678
Journal: BRITISH JOURNAL OF SURGERY
Year: 2020
Reference: Br J Surg. 2020 Oct;107(11):e543-e544. doi: 10.1002/bjs.11833. Epub 2020 Aug 18.
Impact factor: 5.676
Publication type: Letter whit IF
Authors: Jawad, Adraoui, An, Yongbo, Bellato, Vittoria, Konishi, Tsuyoshi, Pellino, Gianluca, Sensi, Bruno, Siragusa, Leandro, Franceschilli, Marzia, Sica, Giuseppe S, Kefleyesus, A et al.
DOI: 10.1002/bjs.11833

Restorative surgery for ulcerative colitis in the elderly: an analysis of ileal pouch-anal anastomosis procedures from the American College of Surgeons National Surgical Quality Improvement Program.

PMID: 32803500
Journal: Techniques in Coloproctology
Year: 2020
Reference: Tech Coloproctol. 2020 Aug 16. pii: 10.1007/s10151-020-02327-1. doi: 10.1007/s10151-020-02327-1.
Impact factor: 2.721
Publication type: Paper in international publication
Authors: Pellino, G, Reif de Paula, T, Lawlor, G, Keller, D S et al.
DOI: 10.1007/s10151-020-02327-1

COVID-19 Pandemic: Considerations for resuming normalcy in colorectal service.

PMID: 32790095
Journal: Colorectal Disease
Year: 2020
Reference: Colorectal Dis. 2020 Sep;22(9):1006-1014. doi: 10.1111/codi.15313. Epub 2020 Aug 28.
Impact factor: 2.769
Publication type: Paper in international publication
Authors: Pellino, Gianluca, Vaizey, Carolynne J, Maeda, Yasuko et al.
DOI: 10.1111/codi.15313

Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime-avibactam.

PMID: 30565008
Journal: INFECTION
Year: 2019
Reference: Infection. 2019 Apr;47(2):289-292. doi: 10.1007/s15010-018-1261-y. Epub 2018 Dec 19.
Impact factor: 2.927
Publication type: Paper in international publication
Authors: Roman, Antonio, Los-Arcos, Ibai, Len, Oscar, Martin-Gomez, Maria Teresa, Gonzalez-Lopez, Juan Jose, Saez-Gimenez, Berta, Deu, Maria, Nuvials, Xavier, Ferrer, Ricard, Gavalda, Joan et al.
DOI: 10.1007/s15010-018-1261-y

Seasonal variation of body weight loss after bariatric surgery.

PMID: 30843440
Journal: CHRONOBIOLOGY INTERNATIONAL
Year: 2019
Reference: Chronobiol Int. 2019 May;36(5):672-680. doi: 10.1080/07420528.2019.1580716. Epub 2019 Mar 7.
Impact factor: 2.562
Publication type: Paper in international publication
Authors: Ricart-Jane, David, Cambras, Trinitat, Pardina, Eva, Carmona, Julia, Lecube, Albert, Balibrea, Jose Maria, Caubet, Enric, Gonzalez, Oscar, Vilallonga, Ramon, Cuello, Elena et al.
DOI: 10.1080/07420528.2019.1580716

Use of Topical Antibiotics before Primary Incision Closure to Prevent Surgical Site Infection: A Meta-Analysis.

PMID: 30839242
Journal: Surgical Infections
Year: 2019
Reference: Surg Infect (Larchmt). 2019 May/Jun;20(4):261-270. doi: 10.1089/sur.2018.279. Epub 2019 Mar 6.
Impact factor: 1.921
Publication type: Review in international publication
Authors: Lopez-Cano, Manuel, Kraft, Miquel, Curell, Anna, Puig-Asensio, Mireia, Balibrea, Jose, Armengol-Carrasco, Manuel, Garcia-Alamino, J M et al.
DOI: 10.1089/sur.2018.279

Making the most of scientific medical conferences: a practical guide for students junior trainees.

PMID: 30791168
Journal: Colorectal Disease
Year: 2019
Reference: Colorectal Dis. 2019 Apr;21(4):487-489. doi: 10.1111/codi.14590. Epub 2019 Mar 12.
Impact factor: 2.997
Publication type: Letter or abstract
Authors: Ioannidis, Argyrios, Blanco-Colino, Ruth, Chapman, Stephen J, Soares, Antonio S, Pellino, Gianluca, Frasson, Matteo et al.
DOI: 10.1111/codi.14590

Perioperative transfusion management in gastric cancer surgery: Analysis of the Spanish subset of the EURECCA oesophago-gastric cancer registry.

PMID: 29773261
Journal: CIRUGIA ESPANOLA
Year: 2018
Reference: Cir Esp. 2018 Nov;96(9):546-554. doi: 10.1016/j.ciresp.2018.03.010.
Impact factor: 0.841
Publication type: Paper in national publication
Authors: Osorio, Javier, Jerico, Carlos, Miranda, Coro, Garsot, Elisenda, Luna, Alexis, Miro, Monica, Santamaria, Maite, Artigau, Eva, Rodriguez-Santiago, Joaquin, Castro, Sandra et al.
DOI: 10.1016/j.ciresp.2018.03.010

A survey to identify the breach between evidence and practice in the prevention of surgical infection: Time to take action.

PMID: 29704562
Journal: International Journal of Surgery
Year: 2018
Reference: Int J Surg. 2018 Jun;54(Pt A):290-297. doi: 10.1016/j.ijsu.2018.04.038. Epub 2018 Apr 25.
Impact factor: 2.693
Publication type: Review in national publication
Authors: Badia, Josep M, Casey, Anna L, Rubio-Perez, Ines, Crosby, Cynthia, Arroyo-Garcia, Nares, Del Castillo, Jose Balibrea et al.
DOI: 10.1016/j.ijsu.2018.04.038

Lung Transplantation in Cystic Fibrosis and the Impact of Extracorporeal Circulation.

PMID: 29534846
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2018
Reference: Arch Bronconeumol. 2018 Jun;54(6):313-319. doi: 10.1016/j.arbres.2018.01.013. Epub 2018 Mar 10.
Impact factor: 2.633
Publication type: Paper in national publication
Authors: Jauregui, Alberto, Deu, Maria, Romero, Laura, Roman, Antonio, Moreno, Antonio, Armengol, Manuel, Sole, Juan et al.
DOI: 10.1016/j.arbres.2018.01.013

Treatment of Fistula-in-ano With OTSC((R)) Proctology Clip Device: Short-term Results.

PMID: 29525123
Journal: CIRUGIA ESPANOLA
Year: 2018
Reference: Cir Esp. 2018 Jun - Jul;96(6):369-374. doi: 10.1016/j.ciresp.2018.02.003. Epub 2018 Mar 7.
Impact factor: 0.841
Publication type: Paper in national publication
Authors: Marinello, Franco, Kraft, Miquel, Ridaura, Nuria, Vallribera, Francesc, Espin, Eloy et al.
DOI: 10.1016/j.ciresp.2018.02.003

Cyclin E Amplification/Overexpression Is Associated with Poor Prognosis in Gastric Cancer.

PMID: 25403579
Journal: ANNALS OF ONCOLOGY
Year: 2015
Reference: Ann Oncol. 2015 Feb;26(2):438-9. doi: 10.1093/annonc/mdu535. Epub 2014 Nov 17.
Impact factor: 7.04
Publication type: Letter whit IF
Authors: Alsina, M, Landolfi, S, Aura, C, Caci, K, Jimenez, J, Prudkin, L, Castro, S, Moreno, D, Navalpotro, B, Tabernero, J et al.
DOI: 10.1093/annonc/mdu535

Iodine Deficiency Is Higher in Morbid Obesity in Comparison with Late After Bariatric Surgery and Non-obese Women.

PMID: 24908244
Journal: OBESITY SURGERY
Year: 2015
Reference: Obes Surg. 2015 Jan;25(1):85-9. doi: 10.1007/s11695-014-1313-z.
Impact factor: 3.747
Publication type: Paper in international publication
Authors: Tortosa, Frederic, Lecube, Albert, Zafon, Carles, Gromaz, Adoracion, Fort, Jose Manuel, Caubet, Enric, Baena, Juan Antonio et al.
DOI: 10.1007/s11695-014-1313-z

Early and mid-term results of lung transplantation with donors 60 years and older.

PMID: 25260894
Journal: Interactive Cardiovascular and Thoracic Surgery
Year: 2015
Reference: Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):47-53. doi: 10.1093/icvts/ivu320. Epub 2014 Sep 25.
Impact factor: 1.155
Publication type: Paper in international publication
Authors: Canela, Mercedes, Roman, Antonio, Rello, Jordi, Masnou, Nuria, Ribas, Montse, Lopez, Iker, Zapata, Ricardo, Sole, Juan, Jauregui, Alberto, Deu, Maria et al.
DOI: 10.1093/icvts/ivu320

Blog

News

This pathology, common among patients who have undergone rectal resection due to cancer, causes alterations in bowel function with great impact on quality of life.

The research has received funding from the Spanish Society of Obesity Surgery and the Spanish Association of Surgeons.

The project has led to the development of a visual algorithm, so it can be used as a guide by patients and healthcare professionals.