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Head and Neck Cancer: Biomedical Research Cancer Stem cells

The work of the Biomedical Research in Cancer Stem Cell group focuses mainly on senescence (replicative or stress-induced oncoge). In our laboratory, we carry out several genetic screens based on the detection of new genes / small interfering RNA (siRNA) / microRNAs related to cell proliferation, which have a role in cancer. Therefore, we use different cell models: murine cells, human primary cells or immortalized cells capable of entering senescence.

The objectives of the group are:

  • Identification and characterization of genes / microRNAs in mammary tumors associated with a more aggressive character (triple negative).
  • Identification and characterization of markers in lung, laryngeal and pharyngeal cancer with diagnostic and prognostic value that help to target a more specific chemotherapy treatment.
  • Identification and characterization of populations of cancer stem cells (CSC) in tumors resistant to conventional therapies.
  • Early detection of breast cancer before it manifests itself clinically.
  • Study of new genes involved in cancer from their identification in massive genetic scans at the basic level.
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News

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

The Biomedical Research in Cancer Stem Cells group at VHIR has identified a new therapeutic target and is working to find new therapies for this type of tumor.

On World Cancer Research Day, we highlight the oncology research model of the Vall d'Hebron Campus that allows laboratory results to be transferred as quickly as possible to clinical practice.

Job offers

Investigador Clínic àmbit Pulmó-Grup Recerca en Oncologia
Start date:
15/05/2014
End date:
22/05/2014
Tècnic/a d’Anatomia Patològica
Start date:
12/05/2014
End date:
18/05/2014
Graduat/da en Medicina
Start date:
12/05/2014
End date:
18/05/2014