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Head and Neck Cancer: Biomedical Research Cancer Stem cells

The work of the Biomedical Research in Cancer Stem Cell group focuses mainly on senescence (replicative or stress-induced oncoge). In our laboratory, we carry out several genetic screens based on the detection of new genes / small interfering RNA (siRNA) / microRNAs related to cell proliferation, which have a role in cancer. Therefore, we use different cell models: murine cells, human primary cells or immortalized cells capable of entering senescence.

The objectives of the group are:

  • Identification and characterization of genes / microRNAs in mammary tumors associated with a more aggressive character (triple negative).
  • Identification and characterization of markers in lung, laryngeal and pharyngeal cancer with diagnostic and prognostic value that help to target a more specific chemotherapy treatment.
  • Identification and characterization of populations of cancer stem cells (CSC) in tumors resistant to conventional therapies.
  • Early detection of breast cancer before it manifests itself clinically.
  • Study of new genes involved in cancer from their identification in massive genetic scans at the basic level.

Team

José Salazar Clavijo

José Salazar Clavijo

Research technician
Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Laia Josa Culleré

Laia Josa Culleré

Postdoctoral researcher
Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Laura Vidal Tarrason

Laura Vidal Tarrason

Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Ma Luisa Navarrete Álvaro

Ma Luisa Navarrete Álvaro

Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Marc Pellicer Sarasa

Marc Pellicer Sarasa

Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Maria Lopez Mendoza

Maria Lopez Mendoza

Predoctoral researcher
Head and Neck Cancer: Biomedical Research Cancer Stem cells
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José Salazar Clavijo

José Salazar Clavijo

Research technician
Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Laia Josa Culleré

Laia Josa Culleré

Postdoctoral researcher
Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Laura Vidal Tarrason

Laura Vidal Tarrason

Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Ma Luisa Navarrete Álvaro

Ma Luisa Navarrete Álvaro

Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Marc Pellicer Sarasa

Marc Pellicer Sarasa

Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Maria Lopez Mendoza

Maria Lopez Mendoza

Predoctoral researcher
Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
Blog

News

The sessions were aimed at establishing new collaborations to advance the prevention and treatment of this type of tumour.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

The Biomedical Research in Cancer Stem Cells group at VHIR has identified a new therapeutic target and is working to find new therapies for this type of tumor.