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Headache and Neurological Pain

Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.

Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.

Team

Laila Asskour

Laila Asskour

Research technician
Headache and Neurological Pain
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Nara Ikumi Montserrat

Nara Ikumi Montserrat

Postdoctoral researcher
Headache and Neurological Pain
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Raquel Maria Lastra Borras

Raquel Maria Lastra Borras

Research technician
Headache and Neurological Pain
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Victor José Gallardo Lopez

Victor José Gallardo Lopez

Research technician
Headache and Neurological Pain
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Laila Asskour

Laila Asskour

Research technician
Headache and Neurological Pain
Read more
Nara Ikumi Montserrat

Nara Ikumi Montserrat

Postdoctoral researcher
Headache and Neurological Pain
Read more
Raquel Maria Lastra Borras

Raquel Maria Lastra Borras

Research technician
Headache and Neurological Pain
Read more
Victor José Gallardo Lopez

Victor José Gallardo Lopez

Research technician
Headache and Neurological Pain
Read more

Projects

Fenotipado molecular de pacientes con migrañA según edad y Sexo a través de la cuanTificación de CGRP en saliva para realizar medicina de precisión: estudio FAST.

IP: Patricia Pozo Rosich
Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna, Laura Gómez Dabó
Funding agency: Instituto de Salud Carlos III
Funding: 81070
Reference: PI22/01501
Duration: 01/01/2023 - 31/12/2025

SENSOMIG IMPACT OF SENSORY AND STRESSFUL STIMULI IN A PRECLINICAL MODEL OF CHRONIC MIGRAINE

IP: Patricia Pozo Rosich
Collaborators: Marta Vila Pueyo
Funding agency: EUROPEAN COMMISSION
Funding: 172932.48
Reference: SENSOMIG_H2020-MSCA-IF2020
Duration: 01/09/2022 - 31/08/2024

Biomarcadores neurofisiológicos en migraña

IP: Patricia Pozo Rosich
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 50649.27
Reference: VHIR/BEQUESPREDOC/2020/MARTI
Duration: 01/04/2021 - 30/03/2024

AhEAD: Algoritmo de predicción de Eficacia de respuesta A tratamiento preventivo en pacientes con migraña crónica: marcaDores biológicos y clínicos

IP: Patricia Pozo Rosich
Collaborators: Alicia Alpuente Ruiz, Juli Alonso Farre, Eulalia Gine Cipres, Marta Torres Ferrús, Victor José Gallardo Lopez, Edoardo Caronna
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI19/01684
Duration: 01/01/2020 - 30/06/2024

Publications

The MIGREX study: Prevalence and risk factors of sexual dysfunction among migraine patients.

PMID: 37802552
Journal: Neurologia
Year: 2023
Reference: Neurologia (Engl Ed). 2023 Oct;38(8):541-549. doi: 10.1016/j.nrleng.2021.02.009.
Impact factor:
Publication type: Paper in international publication
Authors: Bohorquez, S; Camina, J; Diaz de Teran, J; Gago-Veiga, A; Gallardo, V J; Gallardo, V J; Gonzalez-Garcia, N; Gonzalez-Quintanilla, V; Gonzalez-Quintanilla, V; Lopez-Veloso, A C et al.
DOI: 10.1016/j.nrleng.2021.02.009

Telemedicine in the management of patients with headache: current situation and recommendations of the Spanish Society of Neurology's Headache Study Group.

PMID: 37858888
Journal: Neurologia
Year: 2023
Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00053-6. doi: 10.1016/j.nrleng.2023.10.001.
Impact factor:
Publication type: Paper in international publication
Authors: Antoniou, Katerina; Aviles, Victoria; Bachs, Anna; Belvis, R; Bermudo, Guadalupe; Blanco, R L; Bonella, Francesco; Ezpeleta, D; Garcia-Azorin, D; Gine-Cipres, E et al.
DOI: 10.1016/j.nrleng.2023.10.001

European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2023 Guidelines.

PMID: 37858453
Journal: EUROPEAN UROLOGY
Year: 2023
Reference: Eur Urol. 2023 Oct 17:S0302-2838(23)03073-7. doi: 10.1016/j.eururo.2023.08.016.
Impact factor:
Publication type: Paper in international publication
Authors: Alfred Witjes, J; Belvis, R; Blanco, R L; Carrion, Albert; Cathomas, Richard; Comperat, Eva; Efstathiou, Jason A; Ezpeleta, D; Fietkau, Rainer; Gakis, Georgios et al.
DOI: 10.1016/j.eururo.2023.08.016

The microbiology of sepsis is more than the application of new technologies in diagnosis.

PMID: 37997862
Journal: Revista Espanola de Quimioterapia
Year: 2023
Reference: Rev Esp Quimioter. 2023 Nov;36 Suppl 1:5-8. doi: 10.37201/req/s01.02.2023. Epub 2023 Nov 24.
Impact factor:
Publication type: Paper in international publication
Authors: Ahn, Andrew H; Amin, Faisal Mohammad; Ashina, Messoud; Dorman, Paul J; Kokturk, Pinar; Larrosa Escartin, M N; Lyras, Leonidas; Martinez-Lopez, M A; Martins, Isabel Pavao; Mitsikostas, Dimos D et al.
DOI: 10.37201/req/s01.02.2023

The contribution of luminance and chromatic channels to color assimilation.

PMID: 35639404
Journal: JOURNAL OF VISION
Year: 2022
Reference: J Vis. 2022 May 3;22(6):10. doi: 10.1167/jov.22.6.10.
Impact factor: 2.154
Publication type: Paper in international publication
Authors: Otazu, Xavier, Cerda-Company, Xim et al.
DOI: 10.1167/jov.22.6.10

Combined technique as first approach in mechanical thrombectomy: Efficacy and safety of REACT catheter combined with stent retriever.

PMID: 35491662
Journal: INTERVENTIONAL NEURORADIOLOGY
Year: 2022
Reference: Interv Neuroradiol. 2022 May 2:15910199221095798. doi: 10.1177/15910199221095798.
Impact factor: 1.61
Publication type: Paper in international publication
Authors: Requena, Manuel, Pinana, Carlos, Olive-Gadea, Marta, Hernandez, David, Boned, Sandra, De Dios, Marta, Rodrigo, Marc, Rivera, Eila, Muchada, Marian, Cuevas, Jose Luis et al.
DOI: 10.1177/15910199221095798

Salivary CGRP can monitor the different migraine phases: CGRP (in)dependent attacks.

PMID: 34601944
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Mar;42(3):186-196. doi: 10.1177/03331024211040467. Epub 2021 Oct 4.
Impact factor: 6.295
Publication type: Paper in international publication
Authors: Asskour, Laila, Caronna, Edoardo, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Gallardo, Victor J, Alpuente, Alicia et al.
DOI: 10.1177/03331024211040467

Epidemiology, work and economic impact of migraine in a large hospital cohort: time to raise awareness and promote sustainability.

PMID: 34282471
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Mar;269(3):1456-1462. doi: 10.1007/s00415-021-10715-2. Epub 2021 Jul 20.
Impact factor: 4.849
Publication type: Paper in international publication
Authors: Gallardo, Victor Jose, Alpuente, Alicia, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Caronna, Edoardo et al.
DOI: 10.1007/s00415-021-10715-2

InterMiG: international differences in the therapeutic approach to migraine patients in specialized headache centers.

PMID: 34030634
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2021
Reference: J Headache Pain. 2021 May 24;22(1):43. doi: 10.1186/s10194-021-01258-y.
Impact factor: 7.277
Publication type: Paper in international publication
Authors: Gago-Veiga, A B, Huhn, J-I, Latysheva, N, Vieira Campos, A, Torres-Ferrus, M, Alpuente Ruiz, A, Sacco, S, Frattale, I, Ornello, R, Ruscheweyh, R et al.
DOI: 10.1186/s10194-021-01258-y

Telemedicine in the management of patients with headache: current situation and recommendations of the Spanish Society of Neurology's Headache Study Group.

PMID: 33867184
Journal: NEUROLOGIA
Year: 2021
Reference: Neurologia (Engl Ed). 2021 Apr 15. pii: S0213-4853(21)00054-2. doi: 10.1016/j.nrl.2021.01.018.
Impact factor: 3.109
Publication type: Paper in national publication
Authors: Belvis, R, Santos-Lasaosa, S, Irimia, P, Lopez Blanco, R, Torres-Ferrus, M, Morollon, N, Lopez-Bravo, A, Garcia-Azorin, D, Minguez-Olaondo, A, Guerrero, A et al.
DOI: 10.1016/j.nrl.2021.01.018

Safety of anti-CGRP monoclonal antibodies in patients with migraine during the COVID-19 pandemic: Present and future implications.

PMID: 33832802
Journal: NEUROLOGIA
Year: 2021
Reference: Neurologia (Engl Ed). 2021 Mar 19. pii: S0213-4853(21)00056-6. doi: 10.1016/j.nrl.2021.03.003.
Impact factor: 3.109
Publication type: Paper in national publication
Authors: Caronna, E, Jose Gallardo, V, Alpuente, A, Torres-Ferrus, M, Sanchez-Mateo, N M, Viguera-Romero, J, Lopez-Veloso, A C, Lopez-Bravo, A, Gago-Veiga, A B, Irimia Sieira, P et al.
DOI: 10.1016/j.nrl.2021.03.003

Early Management of OnabotulinumtoxinA Treatment in Chronic Migraine: Insights from a Real-Life European Multicenter Study.

PMID: 33778933
Journal: Pain and Therapy
Year: 2021
Reference: Pain Ther. 2021 Jun;10(1):637-650. doi: 10.1007/s40122-021-00253-0. Epub 2021 Mar 28.
Impact factor: 5.725
Publication type: Paper in international publication
Authors: Guerzoni, Simona, Ornello, Raffaele, Ahmed, Fayyaz, Negro, Andrea, Miscio, Anna Maria, Santoro, Antonio, Alpuente, Alicia, Russo, Antonio, Silvestro, Marcello, Cevoli, Sabina et al.
DOI: 10.1007/s40122-021-00253-0

Short and Mid-Term Predictors of Response to OnabotulinumtoxinA: Real-Life Experience Observational Study.

PMID: 32086801
Journal: HEADACHE
Year: 2020
Reference: Headache. 2020 Apr;60(4):677-685. doi: 10.1111/head.13765. Epub 2020 Feb 22.
Impact factor: 4.041
Publication type: Paper in international publication
Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Alvarez-Sabin, Jose, Pozo-Rosich, Patricia et al.
DOI: 10.1111/head.13765

How Does Migraine Change After 10 Years? A Clinical Cohort Follow-Up Analysis.

PMID: 32068897
Journal: HEADACHE
Year: 2020
Reference: Headache. 2020 May;60(5):916-928. doi: 10.1111/head.13774. Epub 2020 Feb 18.
Impact factor: 4.041
Publication type: Paper in international publication
Authors: Fonseca, Elena, Caronna, Edoardo, Gallardo, Victor Jose, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Alpuente, Alicia, Gomez-Galvan, Juan Bernardo et al.
DOI: 10.1111/head.13774

Have the IHS Guidelines for controlled trials of acute treatment of migraine attacks been followed? Laying the ground for the 4th edition.

PMID: 32056459
Journal: CEPHALALGIA
Year: 2020
Reference: Cephalalgia. 2020 Jul;40(8):778-787. doi: 10.1177/0333102420906843. Epub 2020 Feb 14.
Impact factor: 4.868
Publication type: Review in international publication
Authors: Alpuente, Alicia, Tassorelli, Cristina, Diener, Hans-Christoph, Silberstein, Stephen D, Pozo-Rosich, Patricia et al.
DOI: 10.1177/0333102420906843

Blog

News

The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.

The results show that tobacco affects the expression of some genes related to the development of this type of headache.

Aquests guardons reconeixen els millors serveis i unitats de l’Estat, tant públics com privats, que busquen l’excel•lència en l’atenció que presten als seus pacients.

Job offers

Biostatistician-Headache Clinical Unit.
Start date:
05/12/2022
End date:
31/12/2022
Document: Download
Research Coordinator-Headache Clinical Unit
Start date:
27/04/2022
End date:
11/05/2022
Document: Download
Statistician-Headache Research Group.
Start date:
14/04/2022
End date:
28/04/2022
Document: Download