About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
IP: Patricia Pozo Rosich Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna, Laura Gómez Dabó Funding agency: Instituto de Salud Carlos III Funding: 81070 Reference: PI22/01501 Duration: 01/01/2023 - 31/12/2025
IP: Patricia Pozo Rosich Collaborators: Marta Vila Pueyo Funding agency: EUROPEAN COMMISSION Funding: 172932.48 Reference: SENSOMIG_H2020-MSCA-IF2020 Duration: 01/09/2022 - 31/08/2024
IP: Patricia Pozo Rosich Collaborators: - Funding agency: Fundació Institut de Recerca HUVH Funding: 50649.27 Reference: VHIR/BEQUESPREDOC/2020/MARTI Duration: 01/04/2021 - 30/03/2024
IP: Patricia Pozo Rosich Collaborators: Alicia Alpuente Ruiz, Eulalia Gine Cipres, Marta Torres Ferrús, Victor José Gallardo Lopez, Edoardo Caronna Funding agency: Instituto de Salud Carlos III Funding: 87120 Reference: PI19/01684 Duration: 01/01/2020 - 30/06/2024
PMID: 37802552 Journal: Neurologia Year: 2023 Reference: Neurologia (Engl Ed). 2023 Oct;38(8):541-549. doi: 10.1016/j.nrleng.2021.02.009. Impact factor: Publication type: Paper in international publication Authors: Bohorquez, S; Camina, J; Diaz de Teran, J; Gago-Veiga, A; Gallardo, V J; Gallardo, V J; Gonzalez-Garcia, N; Gonzalez-Quintanilla, V; Gonzalez-Quintanilla, V; Lopez-Veloso, A C et al. DOI: 10.1016/j.nrleng.2021.02.009
PMID: 37858888 Journal: Neurologia Year: 2023 Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00053-6. doi: 10.1016/j.nrleng.2023.10.001. Impact factor: Publication type: Paper in international publication Authors: Antoniou, Katerina; Aviles, Victoria; Bachs, Anna; Belvis, R; Bermudo, Guadalupe; Blanco, R L; Bonella, Francesco; Ezpeleta, D; Garcia-Azorin, D; Gine-Cipres, E et al. DOI: 10.1016/j.nrleng.2023.10.001
PMID: 37858453 Journal: EUROPEAN UROLOGY Year: 2023 Reference: Eur Urol. 2023 Oct 17:S0302-2838(23)03073-7. doi: 10.1016/j.eururo.2023.08.016. Impact factor: Publication type: Paper in international publication Authors: Alfred Witjes, J; Belvis, R; Blanco, R L; Carrion, Albert; Cathomas, Richard; Comperat, Eva; Efstathiou, Jason A; Ezpeleta, D; Fietkau, Rainer; Gakis, Georgios et al. DOI: 10.1016/j.eururo.2023.08.016
PMID: 37997862 Journal: Revista Espanola de Quimioterapia Year: 2023 Reference: Rev Esp Quimioter. 2023 Nov;36 Suppl 1:5-8. doi: 10.37201/req/s01.02.2023. Epub 2023 Nov 24. Impact factor: Publication type: Paper in international publication Authors: Ahn, Andrew H; Amin, Faisal Mohammad; Ashina, Messoud; Dorman, Paul J; Kokturk, Pinar; Larrosa Escartin, M N; Lyras, Leonidas; Martinez-Lopez, M A; Martins, Isabel Pavao; Mitsikostas, Dimos D et al. DOI: 10.37201/req/s01.02.2023
PMID: 35639404 Journal: JOURNAL OF VISION Year: 2022 Reference: J Vis. 2022 May 3;22(6):10. doi: 10.1167/jov.22.6.10. Impact factor: 2.154 Publication type: Paper in international publication Authors: Otazu, Xavier, Cerda-Company, Xim et al. DOI: 10.1167/jov.22.6.10
PMID: 35491662 Journal: INTERVENTIONAL NEURORADIOLOGY Year: 2022 Reference: Interv Neuroradiol. 2022 May 2:15910199221095798. doi: 10.1177/15910199221095798. Impact factor: 1.61 Publication type: Paper in international publication Authors: Requena, Manuel, Pinana, Carlos, Olive-Gadea, Marta, Hernandez, David, Boned, Sandra, De Dios, Marta, Rodrigo, Marc, Rivera, Eila, Muchada, Marian, Cuevas, Jose Luis et al. DOI: 10.1177/15910199221095798
PMID: 34601944 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Mar;42(3):186-196. doi: 10.1177/03331024211040467. Epub 2021 Oct 4. Impact factor: 6.295 Publication type: Paper in international publication Authors: Asskour, Laila, Caronna, Edoardo, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Gallardo, Victor J, Alpuente, Alicia et al. DOI: 10.1177/03331024211040467
PMID: 34282471 Journal: JOURNAL OF NEUROLOGY Year: 2022 Reference: J Neurol. 2022 Mar;269(3):1456-1462. doi: 10.1007/s00415-021-10715-2. Epub 2021 Jul 20. Impact factor: 4.849 Publication type: Paper in international publication Authors: Gallardo, Victor Jose, Alpuente, Alicia, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Caronna, Edoardo et al. DOI: 10.1007/s00415-021-10715-2
PMID: 34030634 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 May 24;22(1):43. doi: 10.1186/s10194-021-01258-y. Impact factor: 7.277 Publication type: Paper in international publication Authors: Gago-Veiga, A B, Huhn, J-I, Latysheva, N, Vieira Campos, A, Torres-Ferrus, M, Alpuente Ruiz, A, Sacco, S, Frattale, I, Ornello, R, Ruscheweyh, R et al. DOI: 10.1186/s10194-021-01258-y
PMID: 33867184 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Apr 15. pii: S0213-4853(21)00054-2. doi: 10.1016/j.nrl.2021.01.018. Impact factor: 3.109 Publication type: Paper in national publication Authors: Belvis, R, Santos-Lasaosa, S, Irimia, P, Lopez Blanco, R, Torres-Ferrus, M, Morollon, N, Lopez-Bravo, A, Garcia-Azorin, D, Minguez-Olaondo, A, Guerrero, A et al. DOI: 10.1016/j.nrl.2021.01.018
PMID: 33832802 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Mar 19. pii: S0213-4853(21)00056-6. doi: 10.1016/j.nrl.2021.03.003. Impact factor: 3.109 Publication type: Paper in national publication Authors: Caronna, E, Jose Gallardo, V, Alpuente, A, Torres-Ferrus, M, Sanchez-Mateo, N M, Viguera-Romero, J, Lopez-Veloso, A C, Lopez-Bravo, A, Gago-Veiga, A B, Irimia Sieira, P et al. DOI: 10.1016/j.nrl.2021.03.003
PMID: 33778933 Journal: Pain and Therapy Year: 2021 Reference: Pain Ther. 2021 Jun;10(1):637-650. doi: 10.1007/s40122-021-00253-0. Epub 2021 Mar 28. Impact factor: 5.725 Publication type: Paper in international publication Authors: Guerzoni, Simona, Ornello, Raffaele, Ahmed, Fayyaz, Negro, Andrea, Miscio, Anna Maria, Santoro, Antonio, Alpuente, Alicia, Russo, Antonio, Silvestro, Marcello, Cevoli, Sabina et al. DOI: 10.1007/s40122-021-00253-0
PMID: 32086801 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 Apr;60(4):677-685. doi: 10.1111/head.13765. Epub 2020 Feb 22. Impact factor: 4.041 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Alvarez-Sabin, Jose, Pozo-Rosich, Patricia et al. DOI: 10.1111/head.13765
PMID: 32068897 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 May;60(5):916-928. doi: 10.1111/head.13774. Epub 2020 Feb 18. Impact factor: 4.041 Publication type: Paper in international publication Authors: Fonseca, Elena, Caronna, Edoardo, Gallardo, Victor Jose, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Alpuente, Alicia, Gomez-Galvan, Juan Bernardo et al. DOI: 10.1111/head.13774
PMID: 32056459 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Jul;40(8):778-787. doi: 10.1177/0333102420906843. Epub 2020 Feb 14. Impact factor: 4.868 Publication type: Review in international publication Authors: Alpuente, Alicia, Tassorelli, Cristina, Diener, Hans-Christoph, Silberstein, Stephen D, Pozo-Rosich, Patricia et al. DOI: 10.1177/0333102420906843
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
