About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
PMID: 37858888 Journal: Neurologia Year: 2023 Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00053-6. doi: 10.1016/j.nrleng.2023.10.001. Impact factor: Publication type: Paper in international publication Authors: Antoniou, Katerina; Aviles, Victoria; Bachs, Anna; Belvis, R; Bermudo, Guadalupe; Blanco, R L; Bonella, Francesco; Ezpeleta, D; Garcia-Azorin, D; Gine-Cipres, E et al. DOI: 10.1016/j.nrleng.2023.10.001
PMID: 37858453 Journal: EUROPEAN UROLOGY Year: 2023 Reference: Eur Urol. 2023 Oct 17:S0302-2838(23)03073-7. doi: 10.1016/j.eururo.2023.08.016. Impact factor: Publication type: Paper in international publication Authors: Alfred Witjes, J; Belvis, R; Blanco, R L; Carrion, Albert; Cathomas, Richard; Comperat, Eva; Efstathiou, Jason A; Ezpeleta, D; Fietkau, Rainer; Gakis, Georgios et al. DOI: 10.1016/j.eururo.2023.08.016
PMID: 37997862 Journal: Revista Espanola de Quimioterapia Year: 2023 Reference: Rev Esp Quimioter. 2023 Nov;36 Suppl 1:5-8. doi: 10.37201/req/s01.02.2023. Epub 2023 Nov 24. Impact factor: Publication type: Paper in international publication Authors: Ahn, Andrew H; Amin, Faisal Mohammad; Ashina, Messoud; Dorman, Paul J; Kokturk, Pinar; Larrosa Escartin, M N; Lyras, Leonidas; Martinez-Lopez, M A; Martins, Isabel Pavao; Mitsikostas, Dimos D et al. DOI: 10.37201/req/s01.02.2023
PMID: 38106570 Journal: Kidney International Reports Year: 2023 Reference: Kidney Int Rep. 2023 Sep 22;8(12):2754-2764. doi: 10.1016/j.ekir.2023.09.017. eCollection 2023 Dec. Impact factor: Publication type: Paper in international publication Authors: Biondani, Andrea; Cavero, Teresa; Chaperon, Frederique; Daina, Erica; Eisenberger, Ute; Ettrup, Anders; Florea, Ioana; Gackler, Anja; Garcia-Carro, Clara; Jansson, Gary et al. DOI: 10.1016/j.ekir.2023.09.017
PMID: 35672126 Journal: NEUROLOGIA Year: 2022 Reference: Neurologia. 2022 Jun;37(5):390-402. doi: 10.1016/j.nrleng.2019.03.025. Epub 2021 May 26. Impact factor: Publication type: Review in national publication Authors: Belvis, R; Cuadrado, M L; Diaz-Insa, S; Gago-Veiga, A; Guerrero-Peral, A L; Huerta, M; Irimia, P; Lainez, J M; Latorre, G; Leira, R et al. DOI: 10.1016/j.nrleng.2019.03.025
PMID: 35514209 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Oct;42(11-12):1099-1115. doi: 10.1177/03331024221099035. Epub 2022 May 6. Impact factor: Publication type: Paper in international publication Authors: Amin, Faisal Mohammad; Ashina, Messoud; Diener, Hans-Christoph; Dodick, David W; Kurth, Tobias; Lipton, Richard B; Pozo-Rosich, Patricia; Schwedt, Todd J; Silberstein, Stephen D; Szperka, Christina L et al. DOI: 10.1177/03331024221099035
PMID: 35435045 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Sep;42(10):1071-1085. doi: 10.1177/03331024221092423. Epub 2022 Apr 17. Impact factor: Publication type: Review in international publication Authors: Abdul Rashid, Anna Misyail; Baharin, Janudin; Basri, Hamidon; Ching, Siew Mooi; Fernandez, Aaron; Hoo, Fan Kee; Inche Mat, Liyana Najwa; Lee, Kai Wei; Loh, Wei Chao; Mohamad Safiai, Nabil Izzaatie et al. DOI: 10.1177/03331024221092423
PMID: 35392739 Journal: CURRENT MEDICAL RESEARCH AND OPINION Year: 2022 Reference: Curr Med Res Opin. 2022 May;38(5):731-742. doi: 10.1080/03007995.2022.2059975. Epub 2022 Apr 15. Impact factor: Publication type: Paper in international publication Authors: Aurora, Sheena K; Detke, Holland C; Dolezil, David; Li, Lily Q; Pozo-Rosich, Patricia; Reuter, Uwe; Wang, Shufang et al. DOI: 10.1080/03007995.2022.2059975
PMID: 33990144 Journal: CEPHALALGIA Year: 2021 Reference: Cephalalgia. 2021 Sep;41(10):1075-1088. doi: 10.1177/03331024211008401. Epub 2021 May 14. Impact factor: Publication type: Paper in international publication Authors: Campos, Verena Ramirez; Cohen, Joshua M; Ning, Xiaoping; Pazdera, Ladislav; Pozo-Rosich, Patricia; Yang, Ronghua et al. DOI: 10.1177/03331024211008401
PMID: 33950375 Journal: ADVANCES IN THERAPY Year: 2021 Reference: Adv Ther. 2021 Jun;38(6):3154-3165. doi: 10.1007/s12325-021-01708-8. Epub 2021 May 5. Impact factor: Publication type: Paper in international publication Authors: Nicholson, Robert A; Pearlman, Eric M; Pozo-Rosich, Patricia; Rettiganti, Mallikarjuna; Samaan, Karen H; Schwedt, Todd J et al. DOI: 10.1007/s12325-021-01708-8
PMID: 33882889 Journal: BMC MUSCULOSKELETAL DISORDERS Year: 2021 Reference: BMC Musculoskelet Disord. 2021 Apr 21;22(1):372. doi: 10.1186/s12891-021-04248-y. Impact factor: Publication type: Paper in international publication Authors: Alperi, Mercedes; Blanco, Francisco; Castellanos-Moreira, Raul; Diaz-Torne, Cesar; Erra, Alba; Fernandez-Nebro, Antonio; Gomez, Antonio; Gonzalez, Isidoro; Haro, Isabel; Julia, Antonio et al. DOI: 10.1186/s12891-021-04248-y
PMID: 33867184 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Apr 15:S0213-4853(21)00054-2. doi: 10.1016/j.nrl.2021.01.018. Impact factor: Publication type: Paper in national publication Authors: Belvis, R; Ezpeleta, D; Garcia-Azorin, D; Gine-Cipres, E; Gonzalez-Oria, C; Guerrero, A; Irimia, P; Latorre, G; Lopez Blanco, R; Lopez-Bravo, A et al. DOI: 10.1016/j.nrl.2021.01.018
PMID: 32056459 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Jul;40(8):778-787. doi: 10.1177/0333102420906843. Epub 2020 Feb 14. Impact factor: Publication type: Review in international publication Authors: Alpuente, Alicia; Diener, Hans-Christoph; Pozo-Rosich, Patricia; Silberstein, Stephen D; Tassorelli, Cristina et al. DOI: 10.1177/0333102420906843
PMID: 31943195 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 Mar;60(3):576-588. doi: 10.1111/head.13731. Epub 2020 Jan 13. Impact factor: Publication type: Paper in international publication Authors: Berg, Paul H; Hundemer, Hans P; Khanna, Rashna; Krege, John H; Kudrow, David; Ossipov, Michael H; Pozo-Rosich, Patricia et al. DOI: 10.1111/head.13731
PMID: 33146036 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Nov;40(13):1410-1421. doi: 10.1177/0333102420965157. Impact factor: 4.868 Publication type: Paper in international publication Authors: Caronna, Edoardo, Ballve, Alejandro, Llaurado, Arnau, Gallardo, Victor Jose, Maria Ariton, Diana, Lallana, Sofia, Maza, Samuel Lopez, Gadea, Marta Olive, Quibus, Laura, Restrepo, Juan Luis et al. DOI: 10.1177/0333102420965157
PMID: 32968102 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Sep 23;10(1):15527. doi: 10.1038/s41598-020-72220-2. Impact factor: 3.998 Publication type: Paper in international publication Authors: Marti-Marca, Angela, Deco, Gustavo, Cos, Ignasi et al. DOI: 10.1038/s41598-020-72220-2
PMID: 31220392 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2019 Reference: Eur J Neurol. 2019 Dec;26(12):1464-1470. doi: 10.1111/ene.14028. Epub 2019 Jul 18. Impact factor: 4.387 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Alvarez-Sabin, Jose, Pozo-Rosich, Patricia et al. DOI: 10.1111/ene.14028
PMID: 30950844 Journal: CURRENT OPINION IN NEUROLOGY Year: 2019 Reference: Curr Opin Neurol. 2019 Jun;32(3):395-404. doi: 10.1097/WCO.0000000000000689. Impact factor: 4.647 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Alpuente, Alicia, Pozo-Rosich, Patricia et al. DOI: 10.1097/WCO.0000000000000689
PMID: 30834194 Journal: Epilepsy & behavior case reports Year: 2019 Reference: Epilepsy Behav Case Rep. 2019 Feb 7;11:92-95. doi: 10.1016/j.ebcr.2019.01.008. eCollection 2019. Impact factor: 0 Publication type: Paper in international publication Authors: Santamarina, Estevo, Alpuente, Alicia, Maisterra, Olga, Sueiras, Maria, Sarria, Silvana, Guzman, Lorena, Abraira, Laura, Salas-Puig, Javier, Toledo, Manuel et al. DOI: 10.1016/j.ebcr.2019.01.008
PMID: 29771141 Journal: CEPHALALGIA Year: 2019 Reference: Cephalalgia. 2019 Jan;39(1):91-99. doi: 10.1177/0333102418777509. Epub 2018 May 17. Impact factor: 4.438 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Vila-Sala, Carme, Quintana, Manuel, Ajanovic, Sara, Gallardo, Victor Jose, Gomez, Juan Bernardo, Alvarez-Sabin, Jose, Macaya, Alfons, Pozo-Rosich, Patricia et al. DOI: 10.1177/0333102418777509
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
