About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.
The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.
IP: Jacques Gabriel Rivière, Pere Soler Palacín
IP: Jorgina Vila Soler, Pere Soler Palacín
IP: Maria Ángeles Sánchez Durán Collaborators: Josefa Élida Vázquez Méndez, Nerea Maiz Elizaran, Ma Teresa Higueras Sanz, Juliana Esperalba Esquerra, Carlota Rodó Rodríguez, Maite Avilés García, Marie Antoinette Frick Funding agency: Generalitat de Catalunya - Departament de Salut Funding: 78897.17 Reference: SLT021/21/000051 Duration: 01/04/2022 - 31/12/2024
IP: Andres Antón Pagarolas Collaborators: Juliana Esperalba Esquerra, Jorgina Vila Soler, Yolima Cossio Gil, Rocío Rodrigo García, Tomàs Pumarola Suñé, Maria Espiau Guarner, Núria Worner Tomasa, Maria Piñana Moro, Ariadna Carsi Durall, Anna Creus Costa, Alejandra Gonzalez Sánchez, Cristina Andrés Vergés, Narcís Saubí Roca Funding agency: Instituto de Salud Carlos III Funding: 214170 Reference: PI22/00023 Duration: 01/01/2023 - 31/12/2025
IP: Pere Soler Palacín Collaborators: Mónica Martínez Gallo Funding agency: EUROPEAN COMMISSION Funding: 62500 Reference: RECOMB_H2020SCI2017 Duration: 01/01/2018 - 31/12/2024
IP: Pere Soler Palacín Collaborators: Luís Gros Subias, Juliana Esperalba Esquerra, Natalia Ana Mendoza Palomar, Núria Worner Tomasa, Susana Melendo Perez Funding agency: Instituto de Salud Carlos III Funding: 135520 Reference: PI19/01522 Duration: 01/01/2020 - 30/06/2024
PMID: 37351850 Journal: Journal of Crohns & Colitis Year: 2023 Reference: J Crohns Colitis. 2023 Jun 23:jjad108. doi: 10.1093/ecco-jcc/jjad108. Impact factor: Publication type: Paper in international publication Authors: Allocca, Mariangela; Bamias, Giorgos; Barreiro-de Acosta, Manuel; Braithwaite, Tasanee; Burisch, Johan; Ellul, Pierre; Gordon, Hannah; Greuter, Thomas; Harwood, Catherine; Juillerat, Pascal et al. DOI: 10.1093/ecco-jcc/jjad108
PMID: 37479562 Journal: Enfermedades infecciosas y microbiologia clinica ( Year: 2023 Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2023 Jul 19:S2529-993X(23)00196-X. doi: 10.1016/j.eimce.2023.07.002. Impact factor: Publication type: Paper in international publication Authors: Barbero Allende, Jose M; Escudero-Sanchez, Rosa; Fernandez Sampedro, Marta; Garcia Gutierrez, Manuel; Gomez-Junyent, Joan; Guio Carrion, Laura; Morata Ruiz, Laura; Murillo Rubio, Oscar; Portillo, M Eugenia; Rico Nieto, Alicia et al. DOI: 10.1016/j.eimce.2023.07.002
PMID: 37474185 Journal: BMJ Open Year: 2023 Reference: BMJ Open. 2023 Jul 19;13(7):e071997. doi: 10.1136/bmjopen-2023-071997. Impact factor: Publication type: Paper in international publication Authors: Andreu, Meritxell Fors; Arijon, Mercedes Rey; Ariza, Margarita Mendoza; Bedos, Laia Alcoverro; Bielsa-Pascual, Jofre; Calahorro, Asun Teva; Campi, Astrid Francesch; Carcana, Marina Raja; Carrasco, Julia Mitjans; Carreno, Rocio Garrido et al. DOI: 10.1136/bmjopen-2023-071997
PMID: 37597073 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2023 Reference: J Clin Immunol. 2023 Aug 19. doi: 10.1007/s10875-023-01556-x. Impact factor: Publication type: Paper in international publication Authors: Aguilo-Cucurull, Aina; Batlle-Maso, Laura; Castells, Neus; Colobran, Roger; Franco-Jarava, Clara; Garcia-Prat, Marina; Martin-Nalda, Andrea; Martinez-Gallo, Monica; Parra-Martinez, Alba; Riviere, Jacques G et al. DOI: 10.1007/s10875-023-01556-x
PMID: 35752569 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2022 Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2022 Jun 22. pii: S2529-993X(22)00132-0. doi: 10.1016/j.eimce.2022.06.002. Impact factor: 1.731 Publication type: Paper in international publication Authors: Ruiz-Botia, Irene; Riera-Bosch, M Teresa; Rodriguez-Losada, Olalla; Soler-Palacin, Pere; Melendo, Susana; Moraga-Llop, Fernando; Balcells-Ramirez, Joan; Otero-Romero, Susana; Armadans-Gil, Lluis et al. DOI: 10.1016/j.eimce.2022.06.002
PMID: 35754093 Journal: PEDIATRIC PULMONOLOGY Year: 2022 Reference: Pediatr Pulmonol. 2022 Jun 26. doi: 10.1002/ppul.26042. Impact factor: 3.039 Publication type: Paper in international publication Authors: Mesa, Juan Miguel; Dominguez-Rodriguez, Sara; Moraleda, Cinta; Tagarro, Alfredo; Rodriguez, Maria Jose; Galan, Juan Carlos; Barrios, Ana; Del Valle-Perez, Rut; Ballesteros, Alvaro; Calvo, Cristina et al. DOI: 10.1002/ppul.26042
PMID: 35766460 Journal: CLINICAL PEDIATRICS Year: 2022 Reference: Clin Pediatr (Phila). 2022 Jun 29:99228221106429. doi: 10.1177/00099228221106429. Impact factor: 1.168 Publication type: Paper in international publication Authors: Erika, Arno; Alfons, Macaya; Ignacio, Delgado-Alvarez; Ana, Felipe-Rucian; Jorgina, Vila; Duna, Casadesus-Cabral et al. DOI: 10.1177/00099228221106429
PMID: 35770252 Journal: EClinicalMedicine Year: 2022 Reference: EClinicalMedicine. 2022 Jun 25;50:101515. doi: 10.1016/j.eclinm.2022.101515. eCollection 2022 Aug. Impact factor: 0 Publication type: Paper in international publication Authors: Davalos, Veronica; Garcia-Prieto, Carlos A; Alegria, Iosune; Aguilera-Albesa, Sergio; Valencia-Ramos, Juan; Rodriguez-Palmero, Agusti; Ruiz, Montserrat; Planas-Serra, Laura; Jordan, Iolanda; Ferrer, Gerardo et al. DOI: 10.1016/j.eclinm.2022.101515
PMID: 34413139 Journal: Science Immunology Year: 2021 Reference: Sci Immunol. 2021 Aug 19;6(62). pii: 6/62/eabl4340. doi: 10.1126/sciimmunol.abl4340. Impact factor: 17.727 Publication type: Paper in international publication Authors: Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Rosain, Jeremie, Philippot, Quentin, Manry, Jeremy, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Eto, Shohei, Garcia-Prat, Marina et al. DOI: 10.1126/sciimmunol.abl4340
PMID: 34294672 Journal: International journal of neonatal screening Year: 2021 Reference: Int J Neonatal Screen. 2021 Jul 20;7(3). pii: ijns7030046. doi: 10.3390/ijns7030046. Impact factor: 0 Publication type: Paper in international publication Authors: Argudo-Ramirez, Ana, Martin-Nalda, Andrea, Gonzalez de Aledo-Castillo, Jose Manuel, Lopez-Galera, Rosa, Marin-Soria, Jose Luis, Pajares-Garcia, Sonia, Martinez-Gallo, Monica, Garcia-Prat, Marina, Colobran, Roger, Riviere, Jacques G et al. DOI: 10.3390/ijns7030046
PMID: 34133854 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2021 Reference: N Engl J Med. 2021 Jul 1;385(1):11-22. doi: 10.1056/NEJMoa2102968. Epub 2021 Jun 16. Impact factor: 91.253 Publication type: Paper in international publication Authors: Cruces, Pablo, McArdle, Andrew J, Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G, Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H et al. DOI: 10.1056/NEJMoa2102968
PMID: 34097655 Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL Year: 2021 Reference: Pediatr Infect Dis J. 2021 Jul 1;40(7):628-633. doi: 10.1097/INF.0000000000003114. Impact factor: 2.129 Publication type: Paper in international publication Authors: Anton, Andres, Castellarnau, Ester, Delgado, Ignacio, Vazquez, Elida, Gonzalez, Sebastia, Mayol, Lluis, Mendez, Maria, Sole, Eduard, Rosal, Jaume, Andres, Cristina et al. DOI: 10.1097/INF.0000000000003114
PMID: 32972996 Journal: SCIENCE Year: 2020 Reference: Science. 2020 Oct 23;370(6515). pii: science.abd4585. doi: 10.1126/science.abd4585. Epub 2020 Sep 24. Impact factor: 41.845 Publication type: Paper in international publication Authors: Manry, Jeremy, Shaw, Elana, Haljasmagi, Liis, Peterson, Part, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, de Jesus, Adriana Almeida, Belot, Alexandre et al. DOI: 10.1126/science.abd4585
PMID: 32800388 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Dec;56(12):823-825. doi: 10.1016/j.arbres.2020.07.006. Epub 2020 Aug 13. Impact factor: 4.957 Publication type: Letter whit IF Authors: Mendoza-Palomar, Natalia, Soler-Palacin, Pere, Schaaf, H Simon, Soriano-Arandes, Antoni, Melendo-Perez, Susana, Martin-Nalda, Andrea, Lopez-Seguer, Laura, Carreras-Abad, Clara, Espiau, Maria, Martin-Begue, Nieves et al. DOI: 10.1016/j.arbres.2020.07.006
PMID: 32638196 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2020 Reference: J Clin Immunol. 2020 Aug;40(6):901-916. doi: 10.1007/s10875-020-00814-6. Epub 2020 Jul 7. Impact factor: 6.78 Publication type: Paper in international publication Authors: Ehl, Stephan, Elmaksoud, Marwa Abd, Astigarraga, Itziar, Kurjane, Natalja, Bulina, Inita, Kenina, Viktorija, Bryceson, Yenan, Rascon, Jelena, Lortie, Anne, Goldstein, Gal et al. DOI: 10.1007/s10875-020-00814-6
PMID: 32593520 Journal: ANALES DE PEDIATRIA Year: 2020 Reference: An Pediatr (Barc). 2020 Aug;93(2):132-133. doi: 10.1016/j.anpedi.2020.05.002. Epub 2020 Jun 9. Impact factor: 1.313 Publication type: Letter whit IF Authors: Velasco Puyo, Pablo, Riviere, Jacques G, Soler Palacin, Pere, Diaz de Heredia, Cristina, Moreno, Lucas et al. DOI: 10.1016/j.anpedi.2020.05.002
On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.
This appointment is an international recognition of VHIR's immunodeficiency research.
So far, 240 volunteers have been recruited within all the centres set to join adolescents’ clinical trial (named HH3) to test the efficacy, tolerability, and safety of the BIMERVAX® COVID-19 vaccine in adolescents aged 12 to 17.