Infection and Immunity in pediatric patients

The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.

The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.

Projects

Aquest any no hi ha projectes actius.

Publications

Spanish Society of Hospital Pharmacy and the Spanish Society of Pediatric Infectious Diseases (SEFH-SEIP) National Consensus Guidelines for therapeutic drug monitoring of antibiotic and antifungal drugs in pediatric and newborn patients.

PMID: 39271285
Journal: FARMACIA HOSPITALARIA
Year: 2024
Reference: Farm Hosp. 2024 Sep-Oct;48(5):234-245. doi: 10.1016/j.farma.2024.02.012.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Alonso, David; Fernandez-Polo, Aurora; Garrido, Beatriz; Luque, Sonia; Mendoza-Palomar, Natalia; Miarons, Marta; Piqueras, Ana Isabel; Tevar, Enrique; Velasco-Arnaiz, Eneritz et al.
DOI: 10.1016/j.farma.2024.02.012

[Translated article] Therapeutic Drug Monitoring of antibiotic and antifungical drugs in paediatric and newborn patients. Consensus Guidelines of the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Paediatric Infectious Diseases (SEIP).

PMID: 39271287
Journal: FARMACIA HOSPITALARIA
Year: 2024
Reference: Farm Hosp. 2024 Sep-Oct;48(5):T234-T245. doi: 10.1016/j.farma.2024.02.013.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Alonso, David; Fernandez-Polo, Aurora; Garrido, Beatriz; Luque, Sonia; Mendoza-Palomar, Natalia; Miarons, Marta; Piqueras, Ana Isabel; Tevar, Enrique; Velasco-Arnaiz, Eneritz et al.
DOI: 10.1016/j.farma.2024.02.013

Biallelic PI4KA Mutations Disrupt B-Cell Metabolism and Cause B-Cell Lymphopenia and Hypogammaglobulinemia.

PMID: 39312004
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2024
Reference: J Clin Immunol. 2024 Sep 23;45(1):15. doi: 10.1007/s10875-024-01793-8.
Impact factor:
Publication type: Paper in international publication
Authors: Adam, Margaret P; Adams, David; Amel, Hassan; Baple, Emma L; Barberis, Matteo; Barredo, Estibaliz; Bhatia, Sanil; Biondi, Andrea; Borkhardt, Arndt; Brusco, Alfredo et al.
DOI: 10.1007/s10875-024-01793-8

[Translated article] Prioritisation of 2024-2027 initiatives of the strategic Map for outpatient pharmaceutical care of the Spanish Society of Hospital Pharmacy.

PMID: 39362813
Journal: FARMACIA HOSPITALARIA
Year: 2024
Reference: Farm Hosp. 2024 Oct 2:S1130-6343(24)00138-7. doi: 10.1016/j.farma.2024.08.003.
Impact factor:
Publication type: Paper in international publication
Authors: Ferran, Beatriz Bernardez; Framinan, Luis Margusino; Polo, Aurora Fernandez; Sesmero, Jose Manuel Martinez; Velez-Diaz-Pallares, Manuel; Verdugo, Ramon Morillo; Vicente-Escrig, Esther et al.
DOI: 10.1016/j.farma.2024.08.003

Determinants of COVID-19 vaccine hesitancy among students and parents in Sentinel Schools Network of Catalonia, Spain.

PMID: 36893204
Journal: PLoS One
Year: 2023
Reference: PLoS One. 2023 Mar 9;18(3):e0282871. doi: 10.1371/journal.pone.0282871. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Lucia; Bordas, Anna; Casabona, Jordi; Colom-Cadena, Andreu; Folch, Cinta; Ganem, Fabiana; Soriano-Arandes, Antoni et al.
DOI: 10.1371/journal.pone.0282871

Stability of Ampicillin plus Ceftriaxone Combined in Elastomeric Infusion Devices for Outpatient Parenteral Antimicrobial Therapy.

PMID: 36978299
Journal: Antibiotics-Basel
Year: 2023
Reference: Antibiotics (Basel). 2023 Feb 22;12(3):432. doi: 10.3390/antibiotics12030432.
Impact factor:
Publication type: Paper in international publication
Authors: de Alarcon, Aristides; Fernandez-Polo, Aurora; Fernandez-Rubio, Beatriz; Gil-Navarro, Maria V; Gutierrez-Urbon, Jose Maria; Gutierrez-Valencia, Alicia; Herrera-Hidalgo, Laura; Lopez-Cortes, Luis E; Luque-Marquez, Rafael; Luque-Pardos, Sonia et al.
DOI: 10.3390/antibiotics12030432

Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.

PMID: 36538032
Journal: SCIENCE
Year: 2023
Reference: Science. 2023 Feb 10;379(6632):eabo3627. doi: 10.1126/science.abo3627. Epub 2023 Feb 10.
Impact factor:
Publication type: Paper in international publication
Authors: Abel, Laurent; Abel, Laurent; Abolhassani, Hassan; Aguilera-Albesa, Sergio; Aiuti, Alessandro; Akcan, Ozge Metin; Akcay, Nihal; Alavoine, Loubna; Alkan, Gulsum; Alkhater, Suzan A et al.
DOI: 10.1126/science.abo3627

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

PMID: 37020259
Journal: Genome Medicine
Year: 2023
Reference: Genome Med. 2023 Apr 5;15(1):22. doi: 10.1186/s13073-023-01173-8.
Impact factor:
Publication type: Paper in international publication
Authors: Abad, Jorge; Abad, Sebastien; Abassi, Radhiya; Abdelhadi, Nour Mekki; Abdellaoui, Abdelrafie; Abdelmalek, Abdelkrim; Abdoul, Hendy; Abel, Laurent; Abel, Laurent; Abel, Laurent et al.
DOI: 10.1186/s13073-023-01173-8

ENDOBRONCHIAL TUBERCULOSIS IN CHILDREN: DEFINING THE ROLE OF INTERVENTIONAL BRONCHOSCOPY.

PMID: 35950618
Journal: PEDIATRIC PULMONOLOGY
Year: 2022
Reference: Pediatr Pulmonol. 2022 Nov;57(11):2688-2695. doi: 10.1002/ppul.26084. Epub 2022 Aug 24.
Impact factor:
Publication type: Paper in international publication
Authors: Fernandez, Ana Lain; Garcia-Martinez, Laura; Iglesias-Serrano, Ignacio; Lopez, Manuel; Prades, Carles Gine; Soriano-Arandes, Antoni et al.
DOI: 10.1002/ppul.26084

A first update on mapping the human genetic architecture of COVID-19.

PMID: 35922517
Journal: NATURE
Year: 2022
Reference: Nature. 2022 Aug;608(7921):E1-E10. doi: 10.1038/s41586-022-04826-7. Epub 2022 Aug 3.
Impact factor:
Publication type: Letter or abstract
Authors: Abd Elghafar, Mohamed S; Abdel-Aziz, Mahmoud; Abdollahi, Hamed; Abdullah, Tala; Abecasis, Goncalo R; Abedalthagafi, Malak; Abul-Husn, Noura S; Acquilini, Donatella; Adams, Emma L; Adamsara, Alireza et al.
DOI: 10.1038/s41586-022-04826-7

Safety and Acceptance of COVID-19 Vaccination After Multisystem Inflammatory Syndrome in Children (MIS-C) in Spain.

PMID: 35904132
Journal: Journal of the Pediatric Infectious Diseases Society
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 Oct 25;11(10):471-473. doi: 10.1093/jpids/piac076.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Alonso, David; Carrasco-Colom, Jaume; Epalza, Cristina; Escartin-Paredes, Paula; Fumado, Victoria; Grasa, Carlos; Hermoso-Ibanez, Concepcion; Herrero, Blanca; Leoz, Ines; Moraleda, Cinta et al.
DOI: 10.1093/jpids/piac076

Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study.

PMID: 35844497
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Jun 29;13:902837. doi: 10.3389/fimmu.2022.902837. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Antonio; Alvarez, Antonio; Alvarez-Sierra, Daniel; Anton, Andres; Arrese-Munoz, Iria; Bas-Minguet, Jordi; Blanco-Grau, Albert; Blanco-Grau, Albert; Bosch-Nicolau, Pau; Buzon, Maria Jose et al.
DOI: 10.3389/fimmu.2022.902837

Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents.

PMID: 34374424
Journal: Journal of the Pediatric Infectious Diseases Society
Year: 2021
Reference: J Pediatric Infect Dis Soc. 2021 Aug 10. pii: 6347272. doi: 10.1093/jpids/piab024.
Impact factor:
Publication type: Paper in international publication
Authors: Abzug, Mark J; Aftandilian, Catherine; Ardura, Monica I; Arrieta, Antonio; Aviles-Robles, Martha; Belani, Kiran; Berman, David; Boge, Craig L K; Carlesse, Fabianne; Castagnola, Elio et al.
DOI: 10.1093/jpids/piab024

Age-dependency of the Propagation Rate of Coronavirus Disease 2019 Inside School Bubble Groups in Catalonia, Spain.

PMID: 34321438
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2021
Reference: Pediatr Infect Dis J. 2021 Nov 1;40(11):955-961. doi: 10.1097/INF.0000000000003279.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Sergio; Alvarez-Lacalle, Enric; Bassat, Quique; Capdevila, Ramon; Catala, Marti; Garcia-Garcia, Juan Jose; Gatell, Anna; Jordan, Iolanda; Lazcano, Uxue; Lopez, Daniel et al.
DOI: 10.1097/INF.0000000000003279

Newborn Screening for SCID. Experience in Spain (Catalonia).

PMID: 34294672
Journal: International journal of neonatal screening
Year: 2021
Reference: Int J Neonatal Screen. 2021 Jul 20;7(3). pii: ijns7030046. doi: 10.3390/ijns7030046.
Impact factor:
Publication type: Paper in international publication
Authors: Argudo-Ramirez, Ana; Collado, Tatiana; Colobran, Roger; Garcia-Prat, Marina; Garcia-Villoria, Judit; Gonzalez de Aledo-Castillo, Jose Manuel; Lopez-Galera, Rosa; Marin-Soria, Jose Luis; Martin-Nalda, Andrea; Martinez-Gallo, Monica et al.
DOI: 10.3390/ijns7030046

QUANTIFERON-TB GOLD PLUS ASSAY SPECIFICITY IN CHILDREN AND ADOLESCENTS WITH SUSPECTED TUBERCULOSIS-A MULTICENTER CROSS-SECTIONAL STUDY IN SPAIN.

PMID: 34310504
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2021
Reference: Pediatr Infect Dis J. 2021 Sep 1;40(9):e348-e351. doi: 10.1097/INF.0000000000003173.
Impact factor:
Publication type: Letter or abstract
Authors: Bustillo-Alonso, Matilde; Cobo-Vazquez, Elvira; Espiau, Maria; Gamell, Anna; Korta-Murua, Jose Javier; Lobato, Zulema; Monsonis, Manuel; Noguera-Julian, Antoni; Perez-Gorricho, Beatriz; Perez-Porcuna, Tomas et al.
DOI: 10.1097/INF.0000000000003173

[Tocilizumab in a child with acute lymphoblastic leukaemia and COVID-19-related cytokine release syndrome].

PMID: 32593520
Journal: ANALES DE PEDIATRIA
Year: 2020
Reference: An Pediatr (Barc). 2020 Aug;93(2):132-133. doi: 10.1016/j.anpedi.2020.05.002. Epub 2020 Jun 9.
Impact factor:
Publication type: Letter whit IF
Authors: Diaz de Heredia, Cristina; Moreno, Lucas; Riviere, Jacques G; Soler Palacin, Pere; Velasco Puyo, Pablo et al.
DOI: 10.1016/j.anpedi.2020.05.002

COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study.

PMID: 32593339
Journal: Lancet Child & Adolescent Health
Year: 2020
Reference: Lancet Child Adolesc Health. 2020 Sep;4(9):653-661. doi: 10.1016/S2352-4642(20)30177-2. Epub 2020 Jun 25.
Impact factor:
Publication type: Paper in international publication
Authors: Bael, An; Bandi, Srini; Barker, Michael; Berger, Angelika; Berger, Roland; Bernar, Benoit; Bernatoniene, Jolanta; Beuvink, Yvonne; Biebl, Ariane; Bilogortseva, Olga et al.
DOI: 10.1016/S2352-4642(20)30177-2

Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study.

PMID: 31725552
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2020
Reference: Pediatr Infect Dis J. 2020 Feb;39(2):114-120. doi: 10.1097/INF.0000000000002530.
Impact factor:
Publication type: Paper in international publication
Authors: Andersen, Cecilie T; Arendrup, Maiken C; Arsenijevic, Valentina Arsic; Bianchini, Sonia; Castagnola, Elio; Casteleiro, Angela Manzanares; Chmelnik, Martin; Controzzi, Tiziana; Emonts, Marieke; Esposito, Susanna et al.
DOI: 10.1097/INF.0000000000002530

Clinical Outcomes of a Zika Virus Mother-Child Pair Cohort in Spain.

PMID: 32392815
Journal: Pathogens
Year: 2020
Reference: Pathogens. 2020 May 7;9(5). pii: pathogens9050352. doi: 10.3390/pathogens9050352.
Impact factor:
Publication type: Paper in international publication
Authors: Ades, Anthony E; Antolin, Eugenia; Blazquez-Gamero, Daniel; Byrne, Thomas; Cabrera-Lafuente, Marta; Carreras, Elena; De la Calle, Maria; De Ory, Fernando; Duenas, Eva; Espiau, Maria et al.
DOI: 10.3390/pathogens9050352

Development of Secondary Microcephaly After Delivery: Possible Consequence of Mother-Baby Transmission of Zika Virus in Breast Milk.

PMID: 31110169
Journal: The American journal of case reports
Year: 2019
Reference: Am J Case Rep. 2019 May 21;20:723-725. doi: 10.12659/AJCR.915726.
Impact factor:
Publication type: Paper in international publication
Authors: Gazeta, Rosa Estela; Grillo Fajardo, Thamirys C; Moron, Antonio F; Pascalicchio Bertozzi, Ana Paula A; Passos, Saulo D; Rodrigues, Maria Manoela D; Sarmento, Stephanno Gomes Pereira; Silva, Andrea Cristina B; Siqueira Mello, Alexandra; Soriano-Arandes, Antoni et al.
DOI: 10.12659/AJCR.915726

The challenge of the laboratory diagnosis in a confirmed congenital Zika virus syndrome in utero: A case report.

PMID: 31096455
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 May;98(20):e15532. doi: 10.1097/MD.0000000000015532.
Impact factor:
Publication type: Paper in international publication
Authors: Alarcon, Ana; Espasa, Mateu; Espiau, Maria; Frick, Marie Antoinette; Giaquinto, Carlo; Martin-Nalda, Andrea; Martinon-Torres, Federico; Melendo, Susana; Pumarola, Tomas; Rando, Ariadna et al.
DOI: 10.1097/MD.0000000000015532

Extended immunophenotyping reference values in a healthy pediatric population.

PMID: 30334372
Journal: CYTOMETRY PART B-CLINICAL CYTOMETRY
Year: 2019
Reference: Cytometry B Clin Cytom. 2019 May;96(3):223-233. doi: 10.1002/cyto.b.21728. Epub 2018 Oct 17.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilo-Cucurull, Aina; Alvarez-Sierra, Daniel; Briongos-Sebastian, Sara; Colobran, Roger; Franco-Jarava, Clara; Garcia-Prat, Marina; Hernandez-Gonzalez, Manuel; Martin-Nalda, Andrea; Martinez-Gallo, Monica; Montserrat, Isabel et al.
DOI: 10.1002/cyto.b.21728

Recombinant CV-A6 strains related to hand-foot-mouth disease and herpangina at primary care centers (Barcelona, Spain).

PMID: 31033351
Journal: Future Microbiology
Year: 2019
Reference: Future Microbiol. 2019 Apr;14:499-507. doi: 10.2217/fmb-2018-0336. Epub 2019 Apr 29.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Codina, Maria Gema; Esperalba, Juliana; Esso, Diego Van; Fernandes, Paula; Fuentes, Francisco; Gimferrer, Laura; Guasch, Eulalia; Martin, Maria Carmen et al.
DOI: 10.2217/fmb-2018-0336

Ultrasound findings and associated factors to morbidity in Schistosoma haematobium infection in a highly endemic setting.

PMID: 29205689
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2018
Reference: Trop Med Int Health. 2018 Feb;23(2):221-228. doi: 10.1111/tmi.13020. Epub 2017 Dec 20.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, Maria Luisa; Gallego, Sara; Garcia, Cristina Bocanegra; Gil, Eva; Lopez, Teresa; Mendioroz, Jacobo; Molina, Israel; Moreno, Milagros; Pintar, Zeferino; Salvador, Fernando et al.
DOI: 10.1111/tmi.13020

Migrant women living with HIV in Europe: are they facing inequalities in the prevention of mother-to-child-transmission of HIV?: The European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord.

PMID: 28449111
Journal: EUROPEAN JOURNAL OF PUBLIC HEALTH
Year: 2018
Reference: Eur J Public Health. 2018 Feb 1;28(1):55-60. doi: 10.1093/eurpub/ckx048.
Impact factor:
Publication type: Paper in international publication
Authors: Bailey, H; Burns, F; Favarato, G; Prieto, L; Soriano-Arandes, A; Thorne, C et al.
DOI: 10.1093/eurpub/ckx048

Health Status of Asylum Seekers, Spain.

PMID: 29165223
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2018
Reference: Am J Trop Med Hyg. 2018 Jan;98(1):300-307. doi: 10.4269/ajtmh.17-0438. Epub 2018 Jan 1.
Impact factor:
Publication type: Paper in international publication
Authors: Ascaso, Carlos; Ciruelo, Diana Pou; Garcia, Cristina Bocanegra; Maruri, Begona Trevino; Romero, Israel Molina; Sanchez, Francisco Collazos; Serre-Delcor, Nuria; Soriano-Arandes, Antoni; Sulleiro, Elena et al.
DOI: 10.4269/ajtmh.17-0438

LRBA Deficiency in a Patient With a Novel Homozygous Mutation Due to Chromosome 4 Segmental Uniparental Isodisomy.

PMID: 30386343
Journal: Frontiers in Immunology
Year: 2018
Reference: Front Immunol. 2018 Oct 16;9:2397. doi: 10.3389/fimmu.2018.02397. eCollection 2018.
Impact factor: 5.511
Publication type: Paper in international publication
Authors: Soler-Palacin, Pere, Garcia-Prat, Marina, Martin-Nalda, Andrea, Franco-Jarava, Clara, Riviere, Jacques G, Plaja, Alberto, Bezdan, Daniela, Bosio, Mattia, Martinez-Gallo, Monica, Ossowski, Stephan et al.
DOI: 10.3389/fimmu.2018.02397

Control and Management of Congenital Chagas Disease in Europe and Other Non-Endemic Countries: Current Policies and Practices.

PMID: 26932338
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2016
Reference: Trop Med Int Health. 2016 May;21(5):590-6. doi: 10.1111/tmi.12687. Epub 2016 Mar 17.
Impact factor:
Publication type: Paper in international publication
Authors: Angheben, Andrea; Jackson, Yves; Prat, Jordi Gomez I; Serre-Delcor, Nuria; Soriano-Arandes, Antoni; Trevino-Maruri, Begona et al.
DOI: 10.1111/tmi.12687

Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.

PMID: 26748374
Journal: CLINICAL IMMUNOLOGY
Year: 2016
Reference: Clin Immunol. 2016 Feb;163:60-5. doi: 10.1016/j.clim.2015.12.014. Epub 2015 Dec 31.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez de la Campa, Elena; Colobran, Roger; de la Cruz, Xavier; Martin-Nalda, Andrea; Martinez-Gallo, Monica; Pujol-Borrell, Ricardo; Soler-Palacin, Pere et al.
DOI: 10.1016/j.clim.2015.12.014

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