About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.
The group's lines of research are mainly focused on four areas:
Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.
Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).
Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.
Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.
PMID: 35024838 Journal: JAMA Network Open Year: 2022 Reference: JAMA Netw Open. 2022 Jan 4;5(1):e2137277. doi: 10.1001/jamanetworkopen.2021.37277. Impact factor: 8.485 Publication type: Paper in international publication Authors: Almirante, Benito, Natera-Kindelan, Clara, Sorli, Luisa, Borrell, Nuria, Giner-Oncina, Livia, Amador-Prous, Concha, Shaw, Evelyn, Jover-Saenz, Alfredo, Molina, Jose, Martinez-Alvarez, Rosa M et al. DOI: 10.1001/jamanetworkopen.2021.37277
PMID: 35025963 Journal: PLoS Pathogens Year: 2022 Reference: PLoS Pathog. 2022 Jan 13;18(1):e1010171. doi: 10.1371/journal.ppat.1010171. eCollection 2022 Jan. Impact factor: 6.823 Publication type: Paper in international publication Authors: Grau-Exposito, Judith, Perea, David, Suppi, Marina, Massana, Nuria, Vergara, Ander, Soler, Maria Jose, Trinite, Benjamin, Blanco, Julia, Garcia-Perez, Javier, Alcami, Jose et al. DOI: 10.1371/journal.ppat.1010171
PMID: 35018339 Journal: Journal of Epidemiology and Global Health Year: 2022 Reference: Glob Epidemiol. 2022 Jan 7:100071. doi: 10.1016/j.gloepi.2022.100071. Impact factor: 1.719 Publication type: Paper in international publication Authors: Gudiol, Carlota, Moreno, Anna Maria, Morales-Rull, Jose Luis, Rexach, Maria, Sabater, Gladis, Auguet, Teresa, Vidal, Francesc, Lerida, Ana, Rebull, Josep, Khunti, Kamlesh et al. DOI: 10.1016/j.gloepi.2022.100071
PMID: 33648654 Journal: ANALYTICA CHIMICA ACTA Year: 2021 Reference: Anal Chim Acta. 2021 Apr 1;1152:338254. doi: 10.1016/j.aca.2021.338254. Epub 2021 Jan 30. Impact factor: 6.558 Publication type: Paper in international publication Authors: de la Serna, Erica, Arias-Alpizar, Kevin, Borgheti-Cardoso, Livia Neves, Sanchez-Cano, Ana, Sulleiro, Elena, Zarzuela, Francesc, Bosch-Nicolau, Pau, Salvador, Fernando, Molina, Israel, Ramirez, Miriam et al. DOI: 10.1016/j.aca.2021.338254
PMID: 33631003 Journal: TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE Year: 2021 Reference: Trans R Soc Trop Med Hyg. 2021 Oct 1;115(10):1184-1189. doi: 10.1093/trstmh/trab022. Impact factor: 2.184 Publication type: Review in international publication Authors: Zabala, Andrea, Salvador, Fernando, Sanchez-Montalva, Adrian, Bosch-Nicolau, Pau, Escola-Verge, Laura, Espinosa-Pereiro, Juan, Molina, Israel et al. DOI: 10.1093/trstmh/trab022
PMID: 32753480 Journal: SEXUALLY TRANSMITTED INFECTIONS Year: 2021 Reference: Sex Transm Infect. 2021 Mar;97(2):170-171. doi: 10.1136/sextrans-2020-054560. Epub 2020 Aug 4. Impact factor: 3.519 Publication type: Paper in international publication Authors: Willekens, Rein, Sanchez, Irene, Miguel, Lucia, Esperalba, Juliana, Serra-Pladevall, Judit, Martin, Mario, Navarro, Jordi, Falco, Vicenc, Burgos, Joaquin, Ribera, Esteban et al. DOI: 10.1136/sextrans-2020-054560
PMID: 33501995 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2021 Reference: J Antimicrob Chemother. 2021 Mar 12;76(4):1046-1050. doi: 10.1093/jac/dkaa547. Impact factor: 5.79 Publication type: Paper in international publication Authors: Ryan, Pablo, Perez Elias, Maria Jesus, Alejos, Belen, Gutierrez, Maria Mar, Crespo, Manuel, Knobel, Hernando, Ferrando, Ramon, Crespo, Manuel, Ocampo, Antonio, Sanz, Jose et al. DOI: 10.1093/jac/dkaa547
PMID: 32134108 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2020 Reference: J Antimicrob Chemother. 2020 Jul 1;75(7):1955-1960. doi: 10.1093/jac/dkaa072. Impact factor: 5.439 Publication type: Paper in international publication Authors: Navarro, Jordi, Gonzalez-Cordon, Ana, Casado, Jose Luis, Bernardino, Jose I, Domingo, Pere, Portilla, Joaquin, Llibre, Josep Maria, Colomer, Joan, Rial-Crestelo, David, Vizcarra, Pilar et al. DOI: 10.1093/jac/dkaa072
PMID: 32127121 Journal: Eurosurveillance Year: 2020 Reference: Euro Surveill. 2020 Feb;25(8). doi: 10.2807/1560-7917.ES.2020.25.8.1900393. Impact factor: 6.454 Publication type: Paper in international publication Authors: Velasco, Maria, Gimeno-Feliu, Luis Andres, Molina, Israel, Salas-Coronas, Joaquin, Sola, Ivan, Monge-Maillo, Begona, Torrus-Tendero, Diego, Cayla, Joan, de Guzman, Ena Nino, Arellano, Jl Perez et al. DOI: 10.2807/1560-7917.ES.2020.25.8.1900393
PMID: 31821494 Journal: JOURNAL OF TRAVEL MEDICINE Year: 2020 Reference: J Travel Med. 2020 Feb 3;27(1). pii: 5671715. doi: 10.1093/jtm/taz099. Impact factor: 7.089 Publication type: Paper in international publication Authors: Mendoza-Palomar, Natalia, Sulleiro, Elena, Perez-Garcia, Irene, Espiau, Maria, Soriano-Arandes, Antoni, Martin-Nalda, Andrea, Espasa, Mateu, Zarzuela, Francesc, Soler-Palacin, Pere et al. DOI: 10.1093/jtm/taz099
PMID: 31771856 Journal: MEDICINA CLINICA Year: 2020 Reference: Med Clin (Barc). 2020 Feb 14;154(3):101-107. doi: 10.1016/j.medcli.2019.07.026. Epub 2019 Nov 23. Impact factor: 1.635 Publication type: Review in national publication Authors: Ruiz-Camps, Isabel, Aguilar-Company, Juan, Los-Arcos, Ibai et al. DOI: 10.1016/j.medcli.2019.07.026
PMID: 30461599 Journal: SEXUALLY TRANSMITTED DISEASES Year: 2019 Reference: Sex Transm Dis. 2019 May;46(5):e50-e52. doi: 10.1097/OLQ.0000000000000947. Impact factor: 2.27 Publication type: Paper in international publication Authors: Arando, Maider, Espasa, Mateu, Anton, Andres, Gimferrer, Laura, Pinana, Maria, Fernandez-Huerta, Miguel, Gonzalez-Lopez, Juan Jose, Serra-Pladevall, Judit, Pumarola, Tomas, Vall-Mayans, Marti et al. DOI: 10.1097/OLQ.0000000000000947
PMID: 30449728 Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Year: 2019 Reference: Int J Infect Dis. 2019 Jan;78:34-38. doi: 10.1016/j.ijid.2018.10.005. Epub 2018 Oct 25. Impact factor: 3.538 Publication type: Paper in international publication Authors: Macias, Antonio, Sanchez-Montalva, Adrian, Salvador, Fernando, Villar, Ana, Tortola, Teresa, Saborit, Nuria, Molina, Israel et al. DOI: 10.1016/j.ijid.2018.10.005
PMID: 30924870 Journal: JOURNAL OF TRAVEL MEDICINE Year: 2019 Reference: J Travel Med. 2019 Jun 1;26(4). pii: 5423127. doi: 10.1093/jtm/taz022. Impact factor: 4.155 Publication type: Paper in international publication Authors: Oliveira, I, Aznar, M L, Zarzuela, F, Sulleiro, E, Trevino, B, Serre, N, Pou, D, Salvador, F, Sanchez-Montalva, A, Bosch-Nicolau, P et al. DOI: 10.1093/jtm/taz022
PMID: 30565008 Journal: INFECTION Year: 2019 Reference: Infection. 2019 Apr;47(2):289-292. doi: 10.1007/s15010-018-1261-y. Epub 2018 Dec 19. Impact factor: 2.927 Publication type: Paper in international publication Authors: Roman, Antonio, Los-Arcos, Ibai, Len, Oscar, Martin-Gomez, Maria Teresa, Gonzalez-Lopez, Juan Jose, Saez-Gimenez, Berta, Deu, Maria, Nuvials, Xavier, Ferrer, Ricard, Gavalda, Joan et al. DOI: 10.1007/s15010-018-1261-y
PMID: 29205689 Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH Year: 2018 Reference: Trop Med Int Health. 2018 Feb;23(2):221-228. doi: 10.1111/tmi.13020. Epub 2017 Dec 20. Impact factor: 2.541 Publication type: Paper in international publication Authors: Garcia, Cristina Bocanegra, Pintar, Zeferino, Serres, Xavier, Mendioroz, Jacobo, Moreno, Milagros, Gallego, Sara, Lopez, Teresa, Soriano-Arandes, Antoni, Aznar, Maria Luisa, Sikaleta, Nicolau et al. DOI: 10.1111/tmi.13020
PMID: 29381582 Journal: TRANSPLANTATION Year: 2018 Reference: Transplantation. 2018 Feb;102(2S Suppl 2):S81. doi: 10.1097/TP.0000000000002031. Impact factor: 3.96 Publication type: Paper in international publication Authors: Mourao, Paulo Henrique Orlandi, Gavalda, Joan, Salvador, Fernando, Molina, Israel et al. DOI: 10.1097/TP.0000000000002031
PMID: 29381579 Journal: TRANSPLANTATION Year: 2018 Reference: Transplantation. 2018 Feb;102(2S Suppl 2):S60-S65. doi: 10.1097/TP.0000000000002014. Impact factor: 3.96 Publication type: Paper in international publication Authors: Santoro-Lopes, Guilherme, Subramanian, Aruna K, Molina, Israel, Aguado, Jose Maria, Rabagliatti, Ricardo, Len, Oscar et al. DOI: 10.1097/TP.0000000000002014
PMID: 29378626 Journal: Parasites & Vectors Year: 2018 Reference: Parasit Vectors. 2018 Jan 29;11(1):67. doi: 10.1186/s13071-018-2640-z. Impact factor: 3.163 Publication type: Paper in international publication Authors: Aznar-Ruiz-de-Alegria, Maria L, Espasa, Mateu, Ninda, Arlette, Gandasegui, Javier, Sulleiro, Elena, Moreno, Milagros, Salvador, Fernando, Molina, Israel, Rodriguez, Esperanza, Carmena, David et al. DOI: 10.1186/s13071-018-2640-z
PMID: 28294487 Journal: Transplant Infectious Disease Year: 2017 Reference: Transpl Infect Dis. 2017 Jun;19(3). doi: 10.1111/tid.12694. Epub 2017 May 9. Impact factor: 1.719 Publication type: Paper in international publication Authors: Cifrian, J M, Pastor, A, Roman, Antonio, Ussetti, Piedad, Redel-Montero, Javier, Borro, J M, Sole, A, Monforte, Victor, Sintes, Helena, Lopez-Gallo, C et al. DOI: 10.1111/tid.12694
PMID: 28267637 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Sep;23(9):653-658. doi: 10.1016/j.cmi.2017.02.030. Epub 2017 Mar 6. Impact factor: 5.292 Publication type: Paper in international publication Authors: Garcia-Vidal, Carolina, Sanchez-Rodriguez, Irene, Simonetti, Antonella Francesca, Burgos, Joaquin, Viasus, Diego, Martin, Maria Teresa, Falco, Vicenc, Carratala, Jordi et al. DOI: 10.1016/j.cmi.2017.02.030
PMID: 28249672 Journal: REVISTA IBEROAMERICANA DE MICOLOGIA Year: 2017 Reference: Rev Iberoam Micol. 2017 Jan - Mar;34(1):62. doi: 10.1016/j.riam.2017.02.003. Impact factor: 1.33 Publication type: Letter or abstract Authors: Llinares, Pedro, Ruiz, Isabel, Zaragoza, Rafael, Ferrer, Ricard, Rodriguez, Alejandro H, Maseda, Emilio, Grau, Santiago et al. DOI: 10.1016/j.riam.2017.02.003
PMID: 28252530 Journal: AIDS Year: 2017 Reference: AIDS. 2017 Jun 1;31(9):1245-1252. doi: 10.1097/QAD.0000000000001433. Impact factor: 5.003 Publication type: Paper in international publication Authors: Burgos, Joaquin, Curran, Adria, Landolfi, Stefania, Guelar, Ana, Miguel, Lucia, Dinares, MCarmen, Villar, Judith, Navarro, Jordi, Hernandez-Losa, Javier, Falco, Vicenc et al. DOI: 10.1097/QAD.0000000000001433
PMID: 26538507 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2016 Reference: J Antimicrob Chemother. 2016 Feb;71(2):521-30. doi: 10.1093/jac/dkv362. Epub 2015 Nov 3. Impact factor: 4.919 Publication type: Paper in international publication Authors: Causse, Manuel, Gutierrez-Gutierrez, Belen, Roberts, Jason A, Farkas, Andras, Pascual, Alvaro, Rodriguez-Bano, Jesus, de Cueto, Marina, Planes Reig, Ana Maria, Quintano, Fe Tubau, Praena, Julia et al. DOI: 10.1093/jac/dkv362
PMID: 25109886 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2015 Reference: Eur J Clin Microbiol Infect Dis. 2015 Jan;34(1):177-86. doi: 10.1007/s10096-014-2221-9. Epub 2014 Aug 12. Impact factor: 2.668 Publication type: Paper in international publication Authors: Burgos, J, Larrosa, M N, Martinez, A, Belmonte, J, Gonzalez-Lopez, J, Rello, J, Pumarola, T, Pahissa, A, Falco, V et al. DOI: 10.1007/s10096-014-2221-9
PMID: 25378459 Journal: CLINICAL INFECTIOUS DISEASES Year: 2015 Reference: Clin Infect Dis. 2015 Feb 15;60(4):539-48. doi: 10.1093/cid/ciu866. Epub 2014 Nov 6. Impact factor: 8.886 Publication type: Paper in international publication Authors: Rodriguez-Bano, Jesus, Rodriguez-Lopez, Fernando, Tubau, Fe, Martinez-Martinez, Luis, Oliver, Antonio, Calbo, Esther, Granados, Ana, Pomar, Virginia, Pena, Carmen, Cabot, Gabriel et al. DOI: 10.1093/cid/ciu866
PMID: 25359351 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2015 Reference: Eur Respir J. 2015 Mar;45(3):726-37. doi: 10.1183/09031936.00095214. Epub 2014 Oct 30. Impact factor: 7.636 Publication type: Paper in international publication Authors: Riera, Jordi, Caralt, Berta, Lopez, Iker, Augustin, Salvador, Roman, Antonio, Gavalda, Joan, Rello, Jordi et al. DOI: 10.1183/09031936.00095214
PMID: 25336623 Journal: CLINICAL INFECTIOUS DISEASES Year: 2015 Reference: Clin Infect Dis. 2015 Feb 1;60(3):405-14. doi: 10.1093/cid/ciu833. Epub 2014 Oct 21. Impact factor: 8.886 Publication type: Clinical Trials Authors: Suarez, Maria, Aguado, Jose Maria, Vazquez, Lourdes, Fernandez-Ruiz, Mario, Villaescusa, Teresa, Ruiz-Camps, Isabel, Barba, Pere, Silva, Jose T, Batlle, Montserrat, Solano, Carlos et al. DOI: 10.1093/cid/ciu833
PMID: 24412247 Journal: J INFECTION Year: 2014 Reference: J Infect. 2014 Jun;68(6):548-52. doi: 10.1016/j.jinf.2014.01.001. Epub 2014 Jan 8. Impact factor: 4.017 Publication type: Paper in international publication Authors: Meije, Yolanda, Almirante, Benito, Del Pozo, Jose Luis, Martin, Maria Teresa, Fernandez-Hidalgo, Nuria, Shan, Adriana, Basas, Jana, Pahissa, Albert, Gavalda, Joan et al. DOI: 10.1016/j.jinf.2014.01.001
The new protocol has the same efficacy as the standard one, but only a quarter of the duration, reducing dropout rates and side effects.
The initiative, carried out at the Consulate of Bolivia, has resulted in 307 new tests for the diagnosis of Chagas disease
The study shows that blocking the KLRG1 receptor helps to recover the activity of the natural killer cells of the immune system and reactivate the virus reservoir to fight infection.
