About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.
The group's lines of research are mainly focused on four areas:
Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.
Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).
Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.
Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.
PMID: 32015035 Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Year: 2020 Reference: Antimicrob Agents Chemother. 2020 Mar 24;64(4). pii: AAC.02494-19. doi: 10.1128/AAC.02494-19. Print 2020 Mar 24. Impact factor: 4.904 Publication type: Paper in international publication Authors: Gudiol, C, Albasanz-Puig, A, Laporte-Amargos, J, Pallares, N, Mussetti, A, Ruiz-Camps, I, Puerta-Alcalde, P, Abdala, E, Oltolini, C, Akova, M et al. DOI: 10.1128/AAC.02494-19
PMID: 32005558 Journal: MEDICINA CLINICA Year: 2020 Reference: Med Clin (Barc). 2020 Oct 9;155(7):288-294. doi: 10.1016/j.medcli.2019.12.001. Epub 2020 Jan 28. Impact factor: 1.635 Publication type: Paper in national publication Authors: Canas-Ruano, Esperanza, Martin-Castillo, Mario, Raventos, Berta, Burgos, Joaquin, Curran, Adria, Navarro, Jordi, Garcia, Jorge, Suanzes, Paula, Ribera, Esteban, Falco, Vicenc et al. DOI: 10.1016/j.medcli.2019.12.001
PMID: 32001103 Journal: Transplantation Reviews Year: 2020 Reference: Transplant Rev (Orlando). 2020 Apr;34(2):100528. doi: 10.1016/j.trre.2020.100528. Epub 2020 Jan 13. Impact factor: 3.262 Publication type: Review in international publication Authors: Len, Oscar, Los-Arcos, Ibai, Aguado, Jose Maria, Blanes, Marino, Bodro, Marta, Carratala, Jordi, Cordero, Elisa, Farinas, Maria Carmen, Fernandez-Ruiz, Mario, Fortun, Jesus et al. DOI: 10.1016/j.trre.2020.100528
PMID: 31978394 Journal: EXPERIMENTAL PARASITOLOGY Year: 2020 Reference: Exp Parasitol. 2020 Mar;210:107834. doi: 10.1016/j.exppara.2020.107834. Epub 2020 Jan 21. Impact factor: 1.69 Publication type: Paper in international publication Authors: Perin, Luisa, Fonseca, Katia da Silva, de Carvalho, Thais Vieira, Carvalho, Livia Mendes, Madeira, Joao Vitor, Medeiros, Luciana da Fonseca, Molina, Israel, Correa-Oliveira, Rodrigo, Carneiro, Claudia Martins, Vieira, Paula Melo de Abreu et al. DOI: 10.1016/j.exppara.2020.107834
PMID: 30838386 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2019 Reference: J Antimicrob Chemother. 2019 Jun 1;74(6):1693-1700. doi: 10.1093/jac/dkz067. Impact factor: 5.113 Publication type: Paper in international publication Authors: Riera, Melchor, Garcia-Fraile, Lucio, Navarro, Gemma, Curran, Adrian, Poveda, Eva, Garcia, Federico, Blanco, Jose Ramon, Galera, Carlos, Olalla, Julian, Gomez-Sirvent, Juan Luis et al. DOI: 10.1093/jac/dkz067
PMID: 30145037 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2019 Reference: Enferm Infecc Microbiol Clin. 2019 Mar;37(3):183-186. doi: 10.1016/j.eimc.2018.07.005. Epub 2018 Aug 23. Impact factor: 1.685 Publication type: Paper in national publication Authors: Arando, Maider, Mota-Foix, Miriam, Armegol, Pere, Barbera, Maria Jesus, Esperalba, Juliana, Vall-Mayans, Marti et al. DOI: 10.1016/j.eimc.2018.07.005
PMID: 30825700 Journal: Journal of Global Antimicrobial Resistance Year: 2019 Reference: J Glob Antimicrob Resist. 2019 Dec;19:28-31. doi: 10.1016/j.jgar.2019.02.016. Epub 2019 Feb 27. Impact factor: 2.469 Publication type: Paper in international publication Authors: Escola-Verge, Laura, Larrosa, Nieves, Los-Arcos, Ibai, Vinado, Belen, Gonzalez-Lopez, Juan Jose, Pigrau, Carles, Almirante, Benito, Len, Oscar et al. DOI: 10.1016/j.jgar.2019.02.016
PMID: 30815504 Journal: Open Forum Infectious Diseases Year: 2019 Reference: Open Forum Infect Dis. 2019 Jan 16;6(2):ofz036. doi: 10.1093/ofid/ofz036. eCollection 2019 Feb. Impact factor: 3.371 Publication type: Paper in international publication Authors: Gimeno, A, Benito, R, Algarate, S, Gil, J, Ortiz de Lejarazu, R, Rojo, S, Eiros, J M, San Miguel, A, Manzardo, C, Miro, J M et al. DOI: 10.1093/ofid/ofz036
PMID: 28093484 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2017 Reference: J Antimicrob Chemother. 2017 May 1;72(5):1478-1487. doi: 10.1093/jac/dkw562. Impact factor: 5.071 Publication type: Paper in international publication Authors: Martinez-Martinez, Luis, Canton, Rafael, Antonio Lepe, Jose, Causse, Manuel, Gutierrez-Gutierrez, Belen, Pascual, Alvaro, Rodriguez-Bano, Jesus, Bou, German, Sanz, Mercedes, Gurgui, Mercedes et al. DOI: 10.1093/jac/dkw562
PMID: 28062685 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2017 Reference: J Antimicrob Chemother. 2017 Mar 1;72(3):906-913. doi: 10.1093/jac/dkw513. Impact factor: 5.071 Publication type: Paper in international publication Authors: Tumbarello, Mario, Tacconelli, Evelina, Origuen, Julia, Prim, Nuria, Bou, German, Giamarellou, Helen, Bermejo, Joaquin, Hamprecht, Axel, Perez, Federico, Almela, Manuel et al. DOI: 10.1093/jac/dkw513
The new protocol has the same efficacy as the standard one, but only a quarter of the duration, reducing dropout rates and side effects.
The initiative, carried out at the Consulate of Bolivia, has resulted in 307 new tests for the diagnosis of Chagas disease
The study shows that blocking the KLRG1 receptor helps to recover the activity of the natural killer cells of the immune system and reactivate the virus reservoir to fight infection.
