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Infectious Diseases

The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.

The group's lines of research are mainly focused on four areas:

Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.

Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).

Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.

Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.

Publications

Long-term treatment with nebulized colistin in oncological patients with recurrent respiratory infections.

PMID: 35618498
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 May 23. pii: S0025-7753(22)00188-9. doi: 10.1016/j.medcli.2022.03.014.
Impact factor: 1.725
Publication type: Letter or abstract
Authors: Suanzes, Paula, Aguilar-Company, Juan, Rodriguez-Gonzalez, Esther, Martin-Gomez, M Teresa, Gomez-Domingo, M Rosa, Ruiz-Camps, Isabel et al.
DOI: 10.1016/j.medcli.2022.03.014

Recent concepts in fungal involvement in skin and soft tissue infections.

PMID: 34861654
Journal: CURRENT OPINION IN INFECTIOUS DISEASES
Year: 2022
Reference: Curr Opin Infect Dis. 2022 Apr 1;35(2):103-111. doi: 10.1097/QCO.0000000000000806.
Impact factor: 4.915
Publication type: Review in international publication
Authors: Peghin, Maddalena, Ruiz-Camps, Isabel et al.
DOI: 10.1097/QCO.0000000000000806

Correction to: Early Stepdown From Echinocandin to Fluconazole Treatment in Candidemia: A Post Hoc Analysis of Three Cohort Studies.

PMID: 35615301
Journal: Open Forum Infectious Diseases
Year: 2022
Reference: Open Forum Infect Dis. 2022 May 23;9(6):ofac180. doi: 10.1093/ofid/ofac180. eCollection 2022 Jun.
Impact factor: 3.835
Publication type: Letter or abstract
Authors: Garcia-Vidal, C, Soriano, A, Carratala, J, Moreno-Garcia, E, Puerta-Alcalde, P, Gariup, G, Fernandez-Ruiz, M, Lopez Cortes, L E, Cuervo, G, Salavert, M et al.
DOI: 10.1093/ofid/ofac180

Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response.

PMID: 35616530
Journal: eLife
Year: 2022
Reference: Elife. 2022 May 26;11. pii: 78294. doi: 10.7554/eLife.78294.
Impact factor: 8.146
Publication type: Paper in international publication
Authors: Astorga-Gamaza, Antonio, Grau-Exposito, Judith, Burgos, Joaquin, Navarro, Jordi, Curran, Adria, Planas, Bibiana, Suanzes, Paula, Falco, Vicenc, Genesca, Meritxell, Buzon, Maria et al.
DOI: 10.7554/eLife.78294

Association Between Trypanosoma cruzi DNA in Peripheral Blood and Chronic Chagasic Cardiomyopathy: A Systematic Review.

PMID: 35174221
Journal: Frontiers in Cardiovascular Medicine
Year: 2021
Reference: Front Cardiovasc Med. 2022 Jan 31;8:787214. doi: 10.3389/fcvm.2021.787214. eCollection 2021.
Impact factor: 6.05
Publication type: Review in international publication
Authors: Bosch-Nicolau, Pau, Espinosa-Pereiro, Juan, Salvador, Fernando, Sanchez-Montalva, Adrian, Molina, Israel et al.
DOI: 10.3389/fcvm.2021.787214

Travel-related infections presenting in Europe: A 20-year analysis of EuroTravNet surveillance data.

PMID: 35081179
Journal: The Lancet regional health. Europe
Year: 2021
Reference: Lancet Reg Health Eur. 2020 Nov 12;1:100001. doi: 10.1016/j.lanepe.2020.100001. eCollection 2021 Feb.
Impact factor: 0
Publication type: Paper in international publication
Authors: Grobusch, Martin P, Weld, Leisa, Goorhuis, Abraham, Hamer, Davidson H, Schunk, Mirjam, Jordan, Sabine, Mockenhaupt, Frank P, Chappuis, Francois, Asgeirsson, Hilmir, Caumes, Eric et al.
DOI: 10.1016/j.lanepe.2020.100001

Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells.

PMID: 34948390
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Dec 18;22(24). pii: ijms222413592. doi: 10.3390/ijms222413592.
Impact factor: 5.924
Publication type: Paper in international publication
Authors: Peralta-Garcia, Alejandro, Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Grau-Exposito, Judith, Perea, David, Ayinampudi, Vikram, Waldhoer, Maria, Zimmermann, Mirjam, Buzon, Maria J, Genesca, Meritxell et al.
DOI: 10.3390/ijms222413592

Atlas of the HIV-1 Reservoir in Peripheral CD4 T Cells of Individuals on Successful Antiretroviral Therapy.

PMID: 34844430
Journal: mBio
Year: 2021
Reference: mBio. 2021 Dec 21;12(6):e0307821. doi: 10.1128/mBio.03078-21. Epub 2021 Nov 30.
Impact factor: 7.867
Publication type: Paper in international publication
Authors: Galvez, Cristina, Grau-Exposito, Judith, Urrea, Victor, Clotet, Bonaventura, Falco, Vicenc, Buzon, Maria Jose, Martinez-Picado, Javier et al.
DOI: 10.1128/mBio.03078-21

Latent and active tuberculosis infections in migrants and travellers: A retrospective analysis from the Spanish +REDIVI collaborative network.

PMID: 31369899
Journal: Travel Medicine and Infectious Disease
Year: 2020
Reference: Travel Med Infect Dis. 2020 Jul-Aug;36:101460. doi: 10.1016/j.tmaid.2019.07.016. Epub 2019 Jul 29.
Impact factor: 4.589
Publication type: Paper in international publication
Authors: Perez-Ayala, Ana, Torrus, Diego, Ruiz Giardin, Jose Manuel, Monge-Maillo, Begona, Norman, Francesca F, Romero, Monica, Perez-Molina, Jose A, Aguilera, Paloma, Serrano, Maria Martinez, Rodriguez, Magdalena Garcia et al.
DOI: 10.1016/j.tmaid.2019.07.016

Detection of Streptococcus pneumoniae antigen in pleural fluid: usefulness of an immunofluorescence-based lateral flow assay for the diagnosis of pneumococcal pneumonia.

PMID: 32896751
Journal: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Year: 2020
Reference: Diagn Microbiol Infect Dis. 2020 Dec;98(4):115162. doi: 10.1016/j.diagmicrobio.2020.115162. Epub 2020 Aug 5.
Impact factor: 2.499
Publication type: Paper in international publication
Authors: Romero Herrero, Daniel, Soler-Palacin, Pere, Burgos Cibrian, Joaquin, Falco Ferrer, Vicenc, Anton Pagarolas, Andres, Martin-Gomez, M Teresa et al.
DOI: 10.1016/j.diagmicrobio.2020.115162

Biomarkers of fungal infection: Expert opinion on the current situation.

PMID: 31729203
Journal: Revista Espanola de Quimioterapia
Year: 2020
Reference: Rev Esp Quimioter. 2020 Feb;33(1):1-10. Epub 2019 Nov 14.
Impact factor: 1.132
Publication type: Review in international publication
Authors: Bouza, E, Almirante, B, Garcia Rodriguez, J, Garnacho-Montero, J, Salavert, M, Munoz, P, Sanguinetti, M et al.
DOI:

Prevalence of colorectal disease in Enterococcus faecalis infective endocarditis: results of an observational multicenter study.

PMID: 31444092
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Sep;73(9):711-717. doi: 10.1016/j.rec.2019.07.007. Epub 2019 Aug 20.
Impact factor: 4.642
Publication type: Paper in national publication
Authors: Escola-Verge, Laura, Peghin, Maddalena, Givone, Filippo, Perez-Rodriguez, Maria Teresa, Suarez-Varela, Milagros, Meije, Yolanda, Abelenda, Gabriela, Almirante, Benito, Fernandez-Hidalgo, Nuria et al.
DOI: 10.1016/j.rec.2019.07.007

Sexual Transmission of Intestinal Parasites and Other Enteric Pathogens among Men Who Have Sex with Men Presenting Gastrointestinal Symptoms in an STI Unit in Barcelona, Spain: A Cross-Sectional Study.

PMID: 31549611
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2019
Reference: Am J Trop Med Hyg. 2019 Dec;101(6):1388-1391. doi: 10.4269/ajtmh.19-0312.
Impact factor: 2.315
Publication type: Paper in international publication
Authors: Espasa, Mateu, Sulleiro, Elena, Pumarola, Tomas, Garcia-Perez, Jorge-Nestor, Vall, Marti, Fernandez-Huerta, Miguel, Zarzuela, Francesc, Barbera, Maria-Jesus, Arando, Maider, Esperalba, Juliana et al.
DOI: 10.4269/ajtmh.19-0312

Determinants and Outcomes of Late Presentation of HIV Infection in Migrants in Catalonia, Spain: PISCIS Cohort 2004-2016.

PMID: 30377891
Journal: Journal of Immigrant and Minority Health
Year: 2019
Reference: J Immigr Minor Health. 2019 Oct;21(5):920-930. doi: 10.1007/s10903-018-0834-2.
Impact factor: 1.582
Publication type: Paper in international publication
Authors: Conway, Anna S, Esteve, Anna, Fernandez-Quevedo, Manuel, Casabona, Jordi, Falcó Ferrer, Vicenç, Curran Fàbregas, Adria et al.
DOI: 10.1007/s10903-018-0834-2

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors.

PMID: 31449566
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Aug 26;14(8):e0221598. doi: 10.1371/journal.pone.0221598. eCollection 2019.
Impact factor: 2.776
Publication type: Paper in international publication
Authors: Moreno, Santiago, Alejos, Belen, Suarez-Garcia, Ines, Bisbal, Otilia, Iribarren, Jose Antonio, Asensi, Victor, Gorgolas, Miguel, Muga, Roberto, Curran Fàbregas, Adria, Ribera Pascuet, Esteve et al.
DOI: 10.1371/journal.pone.0221598

"Moving Fourth": A Vision Toward Achieving Healthy Living with HIV Beyond Viral Suppression.

PMID: 31532396
Journal: AIDS REVIEWS
Year: 2019
Reference: AIDS Rev. 2019;21(3):135-142. doi: 10.24875/AIDSRev.19000088.
Impact factor: 2.357
Publication type: Paper in international publication
Authors: Verger, Christian, Guaraldi, Giovanni, Arends, Joop, Buhk, Thomas, Cascio, Mario, Curran, Adrian, Teofilo, Eugenio, Berk, Guido Van Den et al.
DOI: 10.24875/AIDSRev.19000088

Drug Resistance of Mycobacterium tuberculosis Complex in a Rural Setting, Angola.

PMID: 29460748
Journal: EMERGING INFECTIOUS DISEASES
Year: 2018
Reference: Emerg Infect Dis. 2018 Mar;24(3):569-572. doi: 10.3201/eid2403.171562.
Impact factor: 7.422
Publication type: Paper in international publication
Authors: Rando-Segura, Ariadna, Aznar, Maria Luisa, Moreno, Maria Milagros, Espasa, Mateu, Sulleiro, Elena, Bocanegra, Cristina, Gil, Eva, Eugenio, Arlete N E, Escartin, Carlos, Zacarias, Adriano et al.
DOI: 10.3201/eid2403.171562

Imported endemic mycoses in Spain: Evolution of hospitalized cases, clinical characteristics and correlation with migratory movements, 1997-2014.

PMID: 29447170
Journal: PLoS Neglected Tropical Diseases
Year: 2018
Reference: PLoS Negl Trop Dis. 2018 Feb 15;12(2):e0006245. doi: 10.1371/journal.pntd.0006245. eCollection 2018 Feb.
Impact factor: 4.367
Publication type: Paper in international publication
Authors: Molina-Morant, Daniel, Sanchez-Montalva, Adrian, Salvador, Fernando, Sao-Aviles, Augusto, Molina, Israel et al.
DOI: 10.1371/journal.pntd.0006245

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) consensus document on the safety of targeted and biologic therapies: an infectious diseases perspective-cell surface receptors and associated signaling pathways.

PMID: 29426804
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2018
Reference: Clin Microbiol Infect. 2018 Jun;24 Suppl 2:S41-S52. doi: 10.1016/j.cmi.2017.12.027. Epub 2018 Feb 7.
Impact factor: 5.394
Publication type: Review in international publication
Authors: Aguilar-Company, J, Fernandez-Ruiz, M, Garcia-Campelo, R, Garrido-Castro, A C, Ruiz-Camps, I et al.
DOI: 10.1016/j.cmi.2017.12.027

Diagnosis, treatment of bacteremia associated with the use of, vascular catheters: That provides a new clinical practice guide.

PMID: 29406955
Journal: Medicina Intensiva
Year: 2018
Reference: Med Intensiva. 2018 Jan - Feb;42(1):1-4. doi: 10.1016/j.medin.2017.12.009.
Impact factor: 1.755
Publication type: Review in national publication
Authors: Almirante, B et al.
DOI: 10.1016/j.medin.2017.12.009

Geographical variation in therapy for bloodstream infections due to multidrug-resistant enterobacteriaceae: a post hoc analysis of the INCREMENT study.

PMID: 28782704
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2017
Reference: Int J Antimicrob Agents. 2017 Nov;50(5):664-672. doi: 10.1016/j.ijantimicag.2017.08.005. Epub 2017 Aug 3.
Impact factor: 4.307
Publication type: Clinical Trials
Authors: Harris, Patrick N A, Pezzani, M Diletta, Gutierrez-Gutierrez, Belen, Viale, Pierluigi, Hsueh, Po-Ren, Rodriguez-Bano, Jesus, Paterson, David L, Pascual, Alvaro, Ruiz-Garbajosa, Patricia, Venditti, Mario et al.
DOI: 10.1016/j.ijantimicag.2017.08.005

Imported Zika Virus in a European City: How to Prevent Local Transmission?

PMID: 28769893
Journal: Frontiers in Microbiology
Year: 2017
Reference: Front Microbiol. 2017 Jul 18;8:1319. doi: 10.3389/fmicb.2017.01319. eCollection 2017.
Impact factor: 4.076
Publication type: Paper in international publication
Authors: Millet, Joan-Pau, Montalvo, Tomas, Bueno-Mari, Ruben, Romero-Tamarit, Arancha, Prats-Uribe, Albert, Fernandez, Lidia, Camprubi, Esteve, Del Bano, Lucia, Peracho, Victor, Figuerola, Jordi et al.
DOI: 10.3389/fmicb.2017.01319

Case Report: Successful Lung Transplantation from a Donor Seropositive for Trypanosoma cruzi Infection (Chagas Disease) to a Seronegative Recipient.

PMID: 28749767
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2017
Reference: Am J Trop Med Hyg. 2017 Oct;97(4):1147-1150. doi: 10.4269/ajtmh.17-0156. Epub 2017 Jul 27.
Impact factor: 2.549
Publication type: Paper in international publication
Authors: Salvador, Fernando, Sanchez-Montalva, Adrian, Sulleiro, Elena, Berastegui, Cristina, Jauregui, Alberto, Pont, Teresa, Los-Arcos, Ibai, Len, Oscar, Gavalda, Joan, Molina, Israel et al.
DOI: 10.4269/ajtmh.17-0156

Fixed-dose combination dolutegravir, abacavir, and lamivudine versus ritonavir-boosted atazanavir plus tenofovir disoproxil fumarate and emtricitabine in previously untreated women with HIV-1 infection (ARIA): week 48 results from a randomised, open-label, non-inferiority, phase 3b study.

PMID: 28729158
Journal: Lancet HIV
Year: 2017
Reference: Lancet HIV. 2017 Dec;4(12):e536-e546. doi: 10.1016/S2352-3018(17)30095-4. Epub 2017 Jul 17.
Impact factor: 9.842
Publication type: Paper in international publication
Authors: Belonosova, Elena, Porteiro, Norma, Walmsley, Sharon, Falco, Vicenc, Man, Choy Y, Aylott, Alicia, Buchanan, Ann M, Wynne, Brian, Vavro, Cindy, Aboud, Michael et al.
DOI: 10.1016/S2352-3018(17)30095-4

Serum galactomannan versus a combination of galactomannan and polymerase chain reaction-based Aspergillus DNA detection for early therapy of invasive aspergillosis in high-risk hematological patients: a randomized controlled trial.

PMID: 25336623
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2015
Reference: Clin Infect Dis. 2015 Feb 1;60(3):405-14. doi: 10.1093/cid/ciu833. Epub 2014 Oct 21.
Impact factor: 8.886
Publication type: Clinical Trials
Authors: Suarez, Maria, Aguado, Jose Maria, Vazquez, Lourdes, Fernandez-Ruiz, Mario, Villaescusa, Teresa, Ruiz-Camps, Isabel, Barba, Pere, Silva, Jose T, Batlle, Montserrat, Solano, Carlos et al.
DOI: 10.1093/cid/ciu833

A registry-based study of non-Aspergillus mould infections in recipients of allogeneic haematopoietic cell transplantation.

PMID: 25636943
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2015
Reference: Clin Microbiol Infect. 2015 Jan;21(1):e1-3. doi: 10.1016/j.cmi.2014.08.006. Epub 2014 Oct 13.
Impact factor: 5.768
Publication type: Letter whit IF
Authors: Fox, M L, Barba, P, Heras, I, Lopez-Parra, M, Gonzalez-Vicent, M, de la Camara, R, Batlle, M, Parody, R, Vallejo, C, Ruiz-Camps, I et al.
DOI: 10.1016/j.cmi.2014.08.006

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

Vall d'Hebron has coordinated this initiative that has carried out numerous training and community awareness activities aimed at empowering young people in sexual and reproductive health issues.