About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.
The group's lines of research are mainly focused on four areas:
Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.
Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).
Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.
Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.
IP: Adrián Sánchez Montalvá Collaborators: Julia Sellares Nadal, Laia Perez Lasarte Funding agency: Instituto de Salud Carlos III Funding: 65000 Reference: CM22/00262 Duration: 01/01/2023 - 31/12/2024
IP: Israel Molina Romero Collaborators: Juan Espinosa Pereiro, Laia Perez Lasarte Funding agency: Instituto de Salud Carlos III Funding: 65000 Reference: CM22/00246 Duration: 31/03/2023 - 30/03/2025
IP: María José Buzón Gómez Collaborators: Laia Perez Lasarte Funding agency: Instituto de Salud Carlos III Funding: 101250 Reference: CPII22/00005 Duration: 04/01/2023 - 03/01/2026
IP: Meritxell Genesca Ferrer Collaborators: Laia Perez Lasarte Funding agency: VHIR Funding: 225000 Reference: VHIR/SENIORITY/2022/GENESCÀ Duration: 19/10/2022 - 18/10/2027
PMID: 37479562 Journal: Enfermedades infecciosas y microbiologia clinica ( Year: 2023 Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2023 Jul 19:S2529-993X(23)00196-X. doi: 10.1016/j.eimce.2023.07.002. Impact factor: Publication type: Paper in international publication Authors: Barbero Allende, Jose M; Escudero-Sanchez, Rosa; Fernandez Sampedro, Marta; Garcia Gutierrez, Manuel; Gomez-Junyent, Joan; Guio Carrion, Laura; Morata Ruiz, Laura; Murillo Rubio, Oscar; Portillo, M Eugenia; Rico Nieto, Alicia et al. DOI: 10.1016/j.eimce.2023.07.002
PMID: 37534372 Journal: Clinical pathology (Thousand Oaks, Ventura County, Year: 2023 Reference: Clin Pathol. 2023 Jul 31;16:2632010X231183693. doi: 10.1177/2632010X231183693. eCollection 2023 Jan-Dec. Impact factor: Publication type: Paper in international publication Authors: Bernet, L; Cordoba, A; Godey, F; Hardisson, D; Peg, V; Prat, A; Rodrigo, M; Ruiz, I; Sanchez-Mendez, J I; Sancho, M et al. DOI: 10.1177/2632010X231183693
PMID: 37545089 Journal: JOURNAL OF BONE AND MINERAL RESEARCH Year: 2023 Reference: J Bone Miner Res. 2023 Aug 6. doi: 10.1002/jbmr.4894. Impact factor: Publication type: Paper in international publication Authors: Abellan, Javier Garcia; Abellan, Javier Garcia; Adsuar, Araceli; Adsuar, Araceli; Agea, Ivan; Agea, Ivan; Agullo, Vanessa; Agullo, Vanessa; Al-Hayani, Aws; Al-Hayani, Aws et al. DOI: 10.1002/jbmr.4894
PMID: 37598051 Journal: MEDICINA CLINICA Year: 2023 Reference: Med Clin (Barc). 2023 Aug 17:S0025-7753(23)00468-2. doi: 10.1016/j.medcli.2023.07.018. Impact factor: Publication type: Paper in national publication Authors: Anton, Andres; Bosch-Nicolau, Pau; Burgos, Joaquin; Eremiev, Simeon; Falco, Vicenc; Len, Oscar; Martin-Gomez, Maria Teresa; Rodriguez-Pardo, Dolors; Romero-Herrera, Dani; Sellares-Nadal, Julia et al. DOI: 10.1016/j.medcli.2023.07.018
PMID: 35680347 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2022 Reference: Enferm Infecc Microbiol Clin. 2022 Jun-Jul;40(6):289-295. doi: 10.1016/j.eimce.2020.10.015. Impact factor: 1.731 Publication type: Paper in national publication Authors: Guillen, Elena, Ayora, Alfonso, Agusti, Antonia, Anton, Andres, Aguilera, Cristina, Vidal, Xavier, Andres, Cristina, Alonso, Manuel, Espuga, Meritxell, Esperalba, Juliana et al. DOI: 10.1016/j.eimce.2020.10.015
PMID: 34544604 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcli.2021.06.012. Epub 2021 Jun 18. Impact factor: 1.725 Publication type: Paper in national publication Authors: Espinosa-Pereiro, Juan, Fernandez-Hidalgo, Nuria, Perez-Hoyos, Santiago, Salvador, Fernando, Dura, Xavier, Miarons, Marta, Anton, Andres, Eremiev-Eremiev, Simeon, Sempere-Gonzalez, Abiu, Monforte-Pallares, Arnau et al. DOI: 10.1016/j.medcli.2021.06.012
PMID: 35660139 Journal: LANCET ONCOLOGY Year: 2022 Reference: Lancet Oncol. 2022 Jul;23(7):865-875. doi: 10.1016/S1470-2045(22)00273-X. Epub 2022 Jun 2. Impact factor: 41.316 Publication type: Paper in international publication Authors: Earnshaw, Irina, Handford, Jasmine, Sita-Lumsden, Ailsa, Apthorp, Eleanor, Vincenzi, Bruno, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo et al. DOI: 10.1016/S1470-2045(22)00273-X
PMID: 35652817 Journal: MEDICAL MYCOLOGY Year: 2022 Reference: Med Mycol. 2022 Jun 2. pii: 6598867. doi: 10.1093/mmy/myac038. Impact factor: 4.076 Publication type: Paper in international publication Authors: Puerta-Alcalde, Pedro, Ruiz-Camps, Isabel, Gudiol, Carlota, Salavert, Miquel, Barba, Pere, Morandeira, Francisco, Jarque, Isidro, Cuervo, Guillermo, Ayats, Josefina, Carratala, Jordi et al. DOI: 10.1093/mmy/myac038
PMID: 34604116 Journal: Frontiers in Cellular and Infection Microbiology Year: 2021 Reference: Front Cell Infect Microbiol. 2021 Sep 15;11:736630. doi: 10.3389/fcimb.2021.736630. eCollection 2021. Impact factor: 5.293 Publication type: Paper in international publication Authors: Silgado, Aroa, Gual-Gonzalez, Lidia, Oliveira-Souto, Ines, Goterris, Lidia, Serre-Delcor, Nuria, Esperalba, Juliana, Gomez-I-Prat, Jordi, Fernandez-Naval, Candela, Molina, Israel, Pumarola, Tomas et al. DOI: 10.3389/fcimb.2021.736630
PMID: 34591866 Journal: PLoS Neglected Tropical Diseases Year: 2021 Reference: PLoS Negl Trop Dis. 2021 Sep 30;15(9):e0009809. doi: 10.1371/journal.pntd.0009809. eCollection 2021 Sep. Impact factor: 4.411 Publication type: Paper in international publication Authors: Shikanai-Yasuda, Maria Aparecida, Mediano, Mauro Felippe Felix, Novaes, Christina Terra Gallafrio, Sousa, Andrea Silvestre de, Sartori, Ana Marli Christovam, Santana, Rodrigo Carvalho, Correia, Dalmo, Castro, Cleudson Nery de, Severo, Marilia Maria Dos Santos, Hasslocher-Moreno, Alejandro Marcel et al. DOI: 10.1371/journal.pntd.0009809
PMID: 34585972 Journal: Microbiology Spectrum Year: 2021 Reference: Microbiol Spectr. 2021 Oct 31;9(2):e0053421. doi: 10.1128/Spectrum.00534-21. Epub 2021 Sep 29. Impact factor: 7.171 Publication type: Paper in international publication Authors: Burgos, Joaquin, Serra-Pladevall, Judit, Marquez-Algaba, Ester, Pigrau, Carles, Bosch-Nicolau, Pau, Vinado, Belen, Almirante, Benito et al. DOI: 10.1128/Spectrum.00534-21
PMID: 34454444 Journal: BMC PUBLIC HEALTH Year: 2021 Reference: BMC Public Health. 2021 Aug 28;21(1):1596. doi: 10.1186/s12889-021-11613-y. Impact factor: 3.295 Publication type: Paper in international publication Authors: Ribas, M A, Domingo, Pere, de Lazzari, Elisa, Miro, Josep M, Casabona, Jordi, Casabona, Jordi, Miro, Jose M, Reyes, Juliana, Bruguera, Andreu, Moreno, Sergio et al. DOI: 10.1186/s12889-021-11613-y
PMID: 31444092 Journal: REVISTA ESPANOLA DE CARDIOLOGIA Year: 2020 Reference: Rev Esp Cardiol (Engl Ed). 2020 Sep;73(9):711-717. doi: 10.1016/j.rec.2019.07.007. Epub 2019 Aug 20. Impact factor: 4.642 Publication type: Paper in national publication Authors: Escola-Verge, Laura, Peghin, Maddalena, Givone, Filippo, Perez-Rodriguez, Maria Teresa, Suarez-Varela, Milagros, Meije, Yolanda, Abelenda, Gabriela, Almirante, Benito, Fernandez-Hidalgo, Nuria et al. DOI: 10.1016/j.rec.2019.07.007
PMID: 31857134 Journal: ANTIVIRAL RESEARCH Year: 2020 Reference: Antiviral Res. 2020 Feb;174:104694. doi: 10.1016/j.antiviral.2019.104694. Epub 2019 Dec 16. Impact factor: 4.101 Publication type: Paper in international publication Authors: Niubo, Jordi, Chen, Qian, Perales, Celia, Soria, Maria Eugenia, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Buti, Maria, Crespo, Javier, Calleja, Jose Luis et al. DOI: 10.1016/j.antiviral.2019.104694
PMID: 32818462 Journal: Lancet Gastroenterology & Hepatology Year: 2020 Reference: Lancet Gastroenterol Hepatol. 2020 Sep;5(9):802-803. doi: 10.1016/S2468-1253(20)30241-7. Impact factor: 14.789 Publication type: Letter or abstract Authors: Almirante, Benito, Basany, Eloy Espin, Pellino, Gianluca et al. DOI: 10.1016/S2468-1253(20)30241-7
PMID: 32804966 Journal: PLoS Neglected Tropical Diseases Year: 2020 Reference: PLoS Negl Trop Dis. 2020 Aug 17;14(8):e0008529. doi: 10.1371/journal.pntd.0008529. eCollection 2020 Aug. Impact factor: 3.885 Publication type: Paper in international publication Authors: Ciapponi, Agustin, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascon, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino et al. DOI: 10.1371/journal.pntd.0008529
PMID: 31628331 Journal: Nature Communications Year: 2019 Reference: Nat Commun. 2019 Oct 18;10(1):4739. doi: 10.1038/s41467-019-12732-2. Impact factor: 11.878 Publication type: Paper in international publication Authors: Sanhueza, Tamara, Tapia, Gustavo, Lloveras, Belen, Fernandez, Marco A, Prado, Julia G, Sole-Sedeno, Josep M, Tarrats, Antoni, Lecumberri, Carla, Manalich-Barrachina, Laura, Centeno-Mediavilla, Cristina et al. DOI: 10.1038/s41467-019-12732-2
PMID: 30680977 Journal: Revista Espanola de Quimioterapia Year: 2019 Reference: Rev Esp Quimioter. 2019 Feb;32(1):78-82. Epub 2019 Jan 25. Impact factor: 0.76 Publication type: Paper in international publication Authors: Bouza, E, Almirante, B, Pano, J R, Pigrau, C, Morte, E, Munoz, P et al. DOI:
PMID: 31587806 Journal: Actas dermo-sifiliograficas Year: 2019 Reference: Actas Dermosifiliogr. 2019 Dec;110(10):841-849. doi: 10.1016/j.ad.2019.03.014. Epub 2019 Oct 3. Impact factor: 0 Publication type: Paper in national publication Authors: Arando, M, Armengol, P, Barbera, M J, Vall-Mayans, M, Curran, A, Caballero, E et al. DOI: 10.1016/j.ad.2019.03.014
PMID: 31377343 Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS Year: 2019 Reference: Int J Antimicrob Agents. 2019 Oct;54(4):442-448. doi: 10.1016/j.ijantimicag.2019.07.017. Epub 2019 Aug 1. Impact factor: 4.615 Publication type: Paper in international publication Authors: Paterson, David, Pascual, Alvaro, Martinez-Martinez, Luis, Rodriguez-Bano, Jesus, Torre-Cisneros, Julian, Almirante Gragera, Benito, Larrosa Escartin, María Nieves, Puig Asensio, Mireia, REIPI ESGBIS INCREMENT Grp, Carmeli, Yehuda et al. DOI: 10.1016/j.ijantimicag.2019.07.017
PMID: 30471896 Journal: REVISTA IBEROAMERICANA DE MICOLOGIA Year: 2018 Reference: Rev Iberoam Micol. 2018 Oct - Dec;35(4):217-221. doi: 10.1016/j.riam.2018.09.001. Epub 2018 Nov 22. Impact factor: 0.989 Publication type: Paper in national publication Authors: Ruiz Camps, Isabel, Salavert Lleti, Miguel et al. DOI: 10.1016/j.riam.2018.09.001
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PMID: 30376868 Journal: MALARIA JOURNAL Year: 2018 Reference: Malar J. 2018 Oct 30;17(1):399. doi: 10.1186/s12936-018-2544-6. Impact factor: 2.845 Publication type: Paper in international publication Authors: Martin-Martin, Yasmina, Salas-Coronas, Joaquin, Cuadros-Gonzalez, Juan, Garcia-Rodriguez, Magdalena, Molina-Romero, Israel, Lopez-Velez, Rogelio, Gobbi, Federico, Calderon-Moreno, Maria, Martin-Echevarria, Esteban, Elia-Lopez, Matilde et al. DOI: 10.1186/s12936-018-2544-6
PMID: 30328410 Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Year: 2018 Reference: Am J Trop Med Hyg. 2018 Nov;99(5):1170-1173. doi: 10.4269/ajtmh.18-0433. Impact factor: 2.564 Publication type: Paper in international publication Authors: Miguel, Lucia, Salvador, Fernando, Sulleiro, Elena, Sanchez-Montalva, Adrian, Molina-Morant, Daniel, Lopez, Isabel, Molina, Israel et al. DOI: 10.4269/ajtmh.18-0433
PMID: 27889253 Journal: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE Year: 2017 Reference: Diagn Microbiol Infect Dis. 2017 Feb;87(2):112-117. doi: 10.1016/j.diagmicrobio.2016.10.010. Epub 2016 Oct 11. Impact factor: 2.401 Publication type: Paper in international publication Authors: Cendejas-Bueno, E, Forastiero, A, Ruiz, I, Mellado, E, Gavalda, J, Gomez-Lopez, A et al. DOI: 10.1016/j.diagmicrobio.2016.10.010
PMID: 27240445 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2017 Reference: Enferm Infecc Microbiol Clin. 2017 Nov;35(9):605-606. doi: 10.1016/j.eimc.2016.04.007. Epub 2016 May 27. Impact factor: 1.714 Publication type: Paper in national publication Authors: Gonzalez-Cruz, Carlos, Espinosa Pereiro, Juan, Aparicio Espanol, Gloria, Falco Ferrer, Vicenc et al. DOI: 10.1016/j.eimc.2016.04.007
PMID: 29042684 Journal: Scientific Reports Year: 2017 Reference: Sci Rep. 2017 Oct 17;7(1):13350. doi: 10.1038/s41598-017-14051-2. Impact factor: 4.259 Publication type: Paper in international publication Authors: Crespo, Anna, Gavalda, Joan, Julian, Esther, Torrents, Eduard et al. DOI: 10.1038/s41598-017-14051-2
PMID: 29020364 Journal: CLINICAL INFECTIOUS DISEASES Year: 2017 Reference: Clin Infect Dis. 2017 Nov 13;65(11):1819-1828. doi: 10.1093/cid/cix646. Impact factor: 8.216 Publication type: Paper in international publication Authors: Cesaro, Simone, Rascon, Jelena, Ruiz Camps, Isabel, Vitek, Antonin, Patriarca, Francesca, Cudillo, Laura, Vrhovac, Radovan, Shaw, Peter J, Wolfs, Tom, O'Brien, Tracey et al. DOI: 10.1093/cid/cix646
PMID: 26880782 Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Year: 2016 Reference: Am J Trop Med Hyg. 2016 Apr;94(4):750-6. doi: 10.4269/ajtmh.15-0583. Epub 2016 Feb 15. Impact factor: 2.453 Publication type: Paper in international publication Authors: Ascaso, Carlos, Romero, Israel Molina, Soley, Mateu Espasa, Serre Delcor, Nuria, Maruri, Begona Trevino, Arandes, Antoni Soriano, Guiu, Isabel Claveria, Essadik, Hakima Ouaarab et al. DOI: 10.4269/ajtmh.15-0583
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PMID: 27959695 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2016 Reference: N Engl J Med. 2016 Dec 29;375(26):2611-2613. doi: 10.1056/NEJMc1607580. Epub 2016 Dec 7. Impact factor: 59.558 Publication type: Letter or abstract Authors: Carreras, Elena, Pumarola, Tomas, Boix, Hector, Sanchez-Seco, Maria P, Suy, Anna, Sulleiro, Elena, Rodo, Carlota, Vazquez, Elida, Bocanegra, Cristina, Molina, Israel et al. DOI: 10.1056/NEJMc1607580
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PMID: 25703212 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2015 Reference: Clin Microbiol Infect. 2015 May;21(5):491.e1-10. doi: 10.1016/j.cmi.2014.12.027. Epub 2015 Jan 14. Impact factor: 5.768 Publication type: Paper in international publication Authors: Garcia, Julio, Puig-Asensio, M, Ruiz-Camps, I, Fernandez-Ruiz, M, Aguado, J M, Munoz, P, Valerio, M, Delgado-Iribarren, A, Merino, P, Bereciartua, E et al. DOI: 10.1016/j.cmi.2014.12.027
PMID: 25581404 Journal: BONE MARROW TRANSPLANTATION Year: 2015 Reference: Bone Marrow Transplant. 2015 Apr;50(4):579-84. doi: 10.1038/bmt.2014.298. Epub 2015 Jan 12. Impact factor: 3.57 Publication type: Paper in international publication Authors: Sierra, J, Valcarcel, D, Rabella, N, Ruiz, I, Navarro, F, Garcia-Cadenas, I, Castillo, N, Barba, P, Esquirol, A, Novelli, S et al. DOI: 10.1038/bmt.2014.298
PMID: 26716982 Journal: PLoS One Year: 2015 Reference: PLoS One. 2015 Dec 30;10(12):e0145701. doi: 10.1371/journal.pone.0145701. eCollection 2015. Impact factor: 3.234 Publication type: Paper in international publication Authors: Garriga, Cesar, Garcia de Olalla, Patricia, Miro, Josep M, Ocana, Inma, Knobel, Hernando, Barbera, Maria Jesus, Humet, Victoria, Domingo, Pere, Gatell, Josep M, Ribera, Esteve et al. DOI: 10.1371/journal.pone.0145701
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PMID: 25168918 Journal: TRIALS Year: 2014 Reference: Trials. 2014 Aug 28;15:338. doi: 10.1186/1745-6215-15-338. Impact factor: 2.117 Publication type: Clinical Trials Authors: Cabrero Martinez, Inmaculada, Rosso Fernandez, Clara, Molina Ortega, Francisco Javier, Gentil, Miguel Angel, Alamo, Jose Maria, Sousa, Jose Maria, Lage Calle, Ernesto, Gash Illescas, Antonia, Sanchez Aguera, Magdalena, Rodriguez Hernandez, Maria Jesus et al. DOI: 10.1186/1745-6215-15-338
PMID: 24056551 Journal: INDIAN JOURNAL OF MEDICAL RESEARCH Year: 2013 Reference: Indian J Med Res. 2013 Jul;138(1):13-5. Impact factor: 2.061 Publication type: Paper in international publication Authors: Falco, Vicenc et al. DOI:
PMID: 23648777 Journal: CIRCULATION Year: 2013 Reference: Circulation. 2013 Jun 11;127(23):2272-84. doi: 10.1161/CIRCULATIONAHA.112.000813. Epub 2013 May 6. Impact factor: 15.202 Publication type: Paper in international publication Authors: Garcia-Cabrera, Emilio, Fernandez-Hidalgo, Nuria, Almirante, Benito, Ivanova-Georgieva, Radka, Noureddine, Mariam, Plata, Antonio, Lomas, Jose M, Galvez-Acebal, Juan, Hidalgo-Tenorio, Carmen, Ruiz-Morales, Josefa et al. DOI: 10.1161/CIRCULATIONAHA.112.000813
PMID: 23922957 Journal: PLoS One Year: 2013 Reference: PLoS One. 2013 Jul 26;8(7):e70201. doi: 10.1371/journal.pone.0070201. Print 2013. Impact factor: 3.73 Publication type: Paper in international publication Authors: Santos, Jose R, Munoz-Moreno, Jose A, Molto, Jose, Prats, Anna, Curran, Adria, Domingo, Pere, Llibre, Josep M, McClernon, Daniel R, Bravo, Isabel, Canet, Jaume et al. DOI: 10.1371/journal.pone.0070201
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PMID: 22713685 Journal: Journal of the International Association of Physicians in AIDS Care Year: 2012 Reference: J Int Assoc Physicians AIDS Care (Chic). 2012 Sep-Oct;11(5):321-8. Epub 2012 Jun 19. Impact factor: Publication type: Letter or abstract Authors: , , , , et al. DOI: 10.1177/1545109712448217
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The new protocol has the same efficacy as the standard one, but only a quarter of the duration, reducing dropout rates and side effects.
The initiative, carried out at the Consulate of Bolivia, has resulted in 307 new tests for the diagnosis of Chagas disease
The study shows that blocking the KLRG1 receptor helps to recover the activity of the natural killer cells of the immune system and reactivate the virus reservoir to fight infection.
