About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.
The group's lines of research are mainly focused on four areas:
Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.
Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).
Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.
Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.
IP: María José Buzón Gómez Collaborators: Nerea Sanchez Gaona Funding agency: Ministerio Economía, Industria y Competitividad Funding: 98250 Reference: PRE2019-087393 Duration: 01/10/2020 - 30/09/2024
IP: María José Buzón Gómez Collaborators: David Perea Pérez Funding agency: Fundació Institut de Recerca HUVH Funding: 50649.27 Reference: VHIR/BEQUESPREDOC/2020/PEREA Duration: 01/05/2021 - 30/04/2024
IP: Israel Molina Romero Collaborators: Maria Luisa Aznar Ruiz de Alegria, Laia Perez Lasarte Funding agency: Instituto de Salud Carlos III Funding: 180000 Reference: JR21/00027 Duration: 26/05/2022 - 25/05/2026
IP: Adrián Sánchez Montalvá Collaborators: Maria Luisa Aznar Ruiz de Alegria, Juan Espinosa Pereiro Funding agency: EUROPEAN COMMISSION Funding: 172200 Reference: EUSAT-RCS_H2020MSCA-RISE2018 Duration: 04/04/2019 - 31/03/2024
PMID: 37726066 Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Year: 2023 Reference: Int J Infect Dis. 2023 Sep 17:S1201-9712(23)00722-1. doi: 10.1016/j.ijid.2023.09.009. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Lopez, Patricia; Alvarez-Lopez, Patricia; Arando, Maider; Arando, Maider; Burgos, Joaquin; Burgos, Joaquin; Buzon, Maria Jose; Buzon, Maria Jose; Curran, Adrian; Curran, Adrian et al. DOI: 10.1016/j.ijid.2023.09.009
PMID: 37725999 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2023 Reference: J Antimicrob Chemother. 2023 Sep 19:dkad285. doi: 10.1093/jac/dkad285. Impact factor: Publication type: Paper in international publication Authors: Ardila, Fernando; Bernal, Enrique; Casadella, Maria; Curran, Adria; Curran, Adria; Echeverria, Patricia; Estrada, Vicente; Fanciulli, Chiara; Gutierrez, Angela; Hernandez, Cristina et al. DOI: 10.1093/jac/dkad285
PMID: 37737627 Journal: Microbiology Spectrum Year: 2023 Reference: Microbiol Spectr. 2023 Sep 22:e0213623. doi: 10.1128/spectrum.02136-23. Impact factor: Publication type: Paper in international publication Authors: Arando, Maider; Arando, Maider; Burgos, Joaquin; Burgos, Joaquin; Falco, Vicenc; Falco, Vicenc; Ferre-Losa, Carles; Hoyos-Mallecot, Yannick; Hoyos-Mallecot, Yannick; Los-Arcos, Ibai et al. DOI: 10.1128/spectrum.02136-23
PMID: 37741278 Journal: Cell Reports Medicine Year: 2023 Reference: Cell Rep Med. 2023 Sep 15:101202. doi: 10.1016/j.xcrm.2023.101202. Impact factor: Publication type: Paper in international publication Authors: Astorga-Gamaza, Antonio; Burgos, Joaquin; Burgos, Joaquin; Buzon, Maria J; Calvet-Mirabent, Marta; Castellvi, Josep; Castellvi, Josep; Curran, Adrian; Curran, Adrian; Falco, Vicenc et al. DOI: 10.1016/j.xcrm.2023.101202
PMID: 35618152 Journal: JOURNAL OF INFECTION Year: 2022 Reference: J Infect. 2022 Aug;85(2):137-146. doi: 10.1016/j.jinf.2022.05.023. Epub 2022 May 23. Impact factor: 6.072 Publication type: Paper in international publication Authors: Lang, Selwyn, Tellez, Adrian, Ambrosioni, Juan, Hernandez-Meneses, Marta, Llopis, Jaume, Ripa, Marco, Chambers, Stephen T, Holland, David, Almela, Manel, Fernandez-Hidalgo, Nuria et al. DOI: 10.1016/j.jinf.2022.05.023
PMID: 35616530 Journal: eLife Year: 2022 Reference: Elife. 2022 May 26;11. pii: 78294. doi: 10.7554/eLife.78294. Impact factor: 8.146 Publication type: Paper in international publication Authors: Astorga-Gamaza, Antonio, Grau-Exposito, Judith, Burgos, Joaquin, Navarro, Jordi, Curran, Adria, Planas, Bibiana, Suanzes, Paula, Falco, Vicenc, Genesca, Meritxell, Buzon, Maria et al. DOI: 10.7554/eLife.78294
PMID: 34863919 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2022 Reference: Clin Microbiol Infect. 2022 Jun;28(6):881.e1-881.e5. doi: 10.1016/j.cmi.2021.11.021. Epub 2021 Dec 1. Impact factor: 8.067 Publication type: Paper in international publication Authors: Bosch-Nicolau, P, Salvador, F, Sanchez-Montalva, A, Franco-Jarava, C, Arrese-Munoz, I, Sulleiro, E, Roure, S, Valerio, Ll, Oliveira-Souto, I, Serre-Delcor, N et al. DOI: 10.1016/j.cmi.2021.11.021
PMID: 35574695 Journal: EXPERT OPINION ON PHARMACOTHERAPY Year: 2022 Reference: Expert Opin Pharmacother. 2022 Jun 27:1-11. doi: 10.1080/14656566.2022.2077101. Impact factor: 3.889 Publication type: Review in international publication Authors: Marquez-Algaba, Ester, Burgos, Joaquin, Almirante, Benito et al. DOI: 10.1080/14656566.2022.2077101
PMID: 34394703 Journal: Nano Today Year: 2021 Reference: Nano Today. 2021 Feb;36. doi: 10.1016/j.nantod.2020.101056. Epub 2020 Dec 20. Impact factor: 20.722 Publication type: Paper in international publication Authors: Buzon, Maria J, Puntes, Victor, Genesca, Meritxell, Astorga-Gamaza, Antonio, Vitali, Michele, Borrajo, Mireya L, Jaime, Carlos, Bastus, Neus, Serra-Peinado, Carla, Luque-Ballesteros, Laura et al. DOI: 10.1016/j.nantod.2020.101056
PMID: 34384612 Journal: MEDICINA CLINICA Year: 2021 Reference: Med Clin (Barc). 2021 Jul 26. pii: S0025-7753(21)00433-4. doi: 10.1016/j.medcli.2021.07.005. Impact factor: 1.725 Publication type: Letter whit IF Authors: Escola-Verge, Laura, Borras-Bermejo, Blanca, Los-Arcos, Ibai, Esperalba, Juliana, Ferrer, Carmen, Fernandez-Hidalgo, Nuria et al. DOI: 10.1016/j.medcli.2021.07.005
PMID: 34358497 Journal: Lancet HIV Year: 2021 Reference: Lancet HIV. 2021 Aug;8(8):e463-e473. doi: 10.1016/S2352-3018(21)00100-4. Impact factor: 12.767 Publication type: Paper in international publication Authors: Rojas, Jhon, de Lazzari, Elisa, Negredo, Eugenia, Domingo, Pere, Tiraboschi, Juan, Ribera, Esteve, Abdulghani, Nadia, Podzamczer, Daniel, Gutierrez, Maria M, Paredes, Roger et al. DOI: 10.1016/S2352-3018(21)00100-4
PMID: 34294520 Journal: REVISTA IBEROAMERICANA DE MICOLOGIA Year: 2021 Reference: Rev Iberoam Micol. 2021 Apr-Jun;38(2):47-51. doi: 10.1016/j.riam.2021.03.003. Epub 2021 Jul 20. Impact factor: 1.044 Publication type: Review in national publication Authors: Silva, Jose Tiago, Ruiz-Camps, Isabel, Aguado, Jose Maria et al. DOI: 10.1016/j.riam.2021.03.003
PMID: 32632084 Journal: Revista Espanola de Salud Publica Year: 2020 Reference: Rev Esp Salud Publica. 2020 Jul 7;94. Impact factor: 0.746 Publication type: Paper in national publication Authors: Ouaarab Essadek, Hakima, Borras Bermejo, Blanca, Caro Mendivelso, Johanna, Rodriguez Arjona, L Laia, Bisobe, Apolonia, Claveria Guiu, Isabel, Gomez I Prat, Jordi et al. DOI:
PMID: 32619732 Journal: Travel Medicine and Infectious Disease Year: 2020 Reference: Travel Med Infect Dis. 2020 Jun 30:101814. doi: 10.1016/j.tmaid.2020.101814. Impact factor: 4.589 Publication type: Paper in international publication Authors: Souto, Ines Oliveira, Hamer, Davidson H, Parola, Philippe, Javelle, Emilie, Asgeirsson, Hilmir, Field, Vanessa, Malvy, Denis, Grobusch, Martin P, Dudouet, Pierre, Gautret, Philippe et al. DOI: 10.1016/j.tmaid.2020.101814
PMID: 32619707 Journal: Nanomedicine-Nanotechnology Biology and Medicine Year: 2020 Reference: Nanomedicine. 2020 Oct;29:102259. doi: 10.1016/j.nano.2020.102259. Epub 2020 Jul 1. Impact factor: 5.182 Publication type: Paper in international publication Authors: Vairo, C, Basas, J, Pastor, M, Palau, M, Gomis, X, Almirante, B, Gainza, E, Hernandez, R M, Igartua, M, Gavalda, J et al. DOI: 10.1016/j.nano.2020.102259
PMID: 32574139 Journal: EMERGING INFECTIOUS DISEASES Year: 2020 Reference: Emerg Infect Dis. 2020 Sep;26(9). doi: 10.3201/eid2609.202603. Epub 2020 Jun 23. Impact factor: 6.259 Publication type: Paper in international publication Authors: Abadias, Maria Jose, Roman, Antonio, Pumarola, Tomas, Campins, Magda, Almirante, Benito, Selvi, Marta, Martin, Elisabet, Anton, Andres, Esperalba, Juliana, Borras-Bermejo, Blanca et al. DOI: 10.3201/eid2609.202603
PMID: 31549611 Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Year: 2019 Reference: Am J Trop Med Hyg. 2019 Dec;101(6):1388-1391. doi: 10.4269/ajtmh.19-0312. Impact factor: 2.315 Publication type: Paper in international publication Authors: Espasa, Mateu, Sulleiro, Elena, Pumarola, Tomas, Garcia-Perez, Jorge-Nestor, Vall, Marti, Fernandez-Huerta, Miguel, Zarzuela, Francesc, Barbera, Maria-Jesus, Arando, Maider, Esperalba, Juliana et al. DOI: 10.4269/ajtmh.19-0312
PMID: 30377891 Journal: Journal of Immigrant and Minority Health Year: 2019 Reference: J Immigr Minor Health. 2019 Oct;21(5):920-930. doi: 10.1007/s10903-018-0834-2. Impact factor: 1.582 Publication type: Paper in international publication Authors: Conway, Anna S, Esteve, Anna, Fernandez-Quevedo, Manuel, Casabona, Jordi, Falcó Ferrer, Vicenç, Curran Fàbregas, Adria et al. DOI: 10.1007/s10903-018-0834-2
PMID: 31532396 Journal: AIDS REVIEWS Year: 2019 Reference: AIDS Rev. 2019;21(3):135-142. doi: 10.24875/AIDSRev.19000088. Impact factor: 2.357 Publication type: Paper in international publication Authors: Verger, Christian, Guaraldi, Giovanni, Arends, Joop, Buhk, Thomas, Cascio, Mario, Curran, Adrian, Teofilo, Eugenio, Berk, Guido Van Den et al. DOI: 10.24875/AIDSRev.19000088
PMID: 30561555 Journal: CLINICAL INFECTIOUS DISEASES Year: 2019 Reference: Clin Infect Dis. 2019 Sep 13;69(7):1192-1197. doi: 10.1093/cid/ciy1047. Impact factor: 9.055 Publication type: Paper in international publication Authors: Ferrer, Ricard, Peghin, Maddalena, Los-Arcos, Ibai, Hirsch, Hans H, Codina, Gemma, Monforte, Victor, Bravo, Carles, Berastegui, Cristina, Jauregui, Alberto, Romero, Laura et al. DOI: 10.1093/cid/ciy1047
PMID: 30179983 Journal: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES Year: 2018 Reference: J Acquir Immune Defic Syndr. 2018 Dec 15;79(5):612-616. doi: 10.1097/QAI.0000000000001847. Impact factor: 4.116 Publication type: Paper in international publication Authors: Landolfi, S, Burgos, J, Martin-Castillo, M, Navarro, J, Ribera, E, Falco, V, Curran, A, Villar, J, Dinares, M femininec et al. DOI: 10.1097/QAI.0000000000001847
PMID: 30141396 Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Year: 2018 Reference: Am J Trop Med Hyg. 2018 Oct;99(4):1011-1017. doi: 10.4269/ajtmh.18-0343. Impact factor: 2.564 Publication type: Paper in international publication Authors: Bocanegra, Cristina, Pintar, Zeferino, Mendioroz, Jacobo, Serres, Xavier, Gallego, Sara, Nindia, Arlette, Aznar, Maria Luisa, Soriano-Arandes, Antoni, Salvador, Fernando, Gil, Eva et al. DOI: 10.4269/ajtmh.18-0343
PMID: 30085184 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2018 Reference: J Antimicrob Chemother. 2018 Nov 1;73(11):2927-2935. doi: 10.1093/jac/dky299. Impact factor: 5.217 Publication type: Paper in international publication Authors: Ribera, E, Perez-Molina, J A, Pulido, F, Di Giambenedetto, S, Coscia, C, Alejos, B, Pitch, J, Gatell, J M, De Luca, A, Arribas, J R et al. DOI: 10.1093/jac/dky299
PMID: 30073433 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2018 Reference: Eur J Clin Microbiol Infect Dis. 2018 Nov;37(11):2075-2082. doi: 10.1007/s10096-018-3341-4. Epub 2018 Aug 2. Impact factor: 2.537 Publication type: Paper in international publication Authors: Barba, Pere, Aguilar-Company, Juan, Rodriguez, Virginia, Roig, Gloria, Ferrer, Carmen, Ruiz-Camps, Isabel, Almirante, Benito, Rodriguez-Pardo, Dolors, Larrainzar-Coghen, Thais et al. DOI: 10.1007/s10096-018-3341-4
PMID: 28971876 Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Year: 2017 Reference: Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: AAC.01317-17. doi: 10.1128/AAC.01317-17. Print 2017 Dec. Impact factor: 4.302 Publication type: Paper in international publication Authors: Bosch-Nicolau, Pau, Falco, Vicenc, Vinado, Belen, Andreu, Antonia, Len, Oscar, Almirante, Benito, Pigrau, Carles et al. DOI: 10.1128/AAC.01317-17
PMID: 28945064 Journal: Revista Espanola de Quimioterapia Year: 2017 Reference: Rev Esp Quimioter. 2017 Oct;30(5):355-367. Epub 2017 Sep 25. Impact factor: 0.75 Publication type: Review in national publication Authors: Almirante, B, Garnacho-Montero, J, Maseda, E, Candel, F J, Grau, S, Guinea, J, Moreno, I, Munoz, P, Ruiz-Santana, S et al. DOI:
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PMID: 28931128 Journal: JOURNAL OF TRAVEL MEDICINE Year: 2017 Reference: J Travel Med. 2017 Sep 1;24(5). doi: 10.1093/jtm/tax035. Impact factor: 1.803 Publication type: Paper in international publication Authors: Calabuig, Eva, Benito, Agustin, Lopez-Velez, Rogelio, Torrus, Diego, Diaz-Menendez, Marta, Goikoetxea, Josune, Molina, Israel, Perez-Molina, Jose A, Lopez-Polin, Ana, Trevino, Begona et al. DOI: 10.1093/jtm/tax035
PMID: 26678668 Journal: Transplant Infectious Disease Year: 2016 Reference: Transpl Infect Dis. 2016 Feb;18(1):70-8. doi: 10.1111/tid.12492. Epub 2016 Feb 3. Impact factor: 1.459 Publication type: Paper in international publication Authors: Peghin, M, Monforte, V, Martin-Gomez, M T, Ruiz-Camps, I, Berastegui, C, Saez, B, Riera, J, Sole, J, Gavalda, J, Roman, A et al. DOI: 10.1111/tid.12492
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PMID: 25604647 Journal: MALARIA JOURNAL Year: 2015 Reference: Malar J. 2015 Jan 21;14:21. doi: 10.1186/s12936-014-0540-z. Impact factor: 3.109 Publication type: Paper in international publication Authors: Meredith, Warren, Lopez, Teresa, Moreno, Milagros, Molina, Israel, Sulleiro, Elena, Eugenio, Arlette N, Bocanegra, Cristina, Salvador, Fernando, Cossio, Yolima, Riera, Marta et al. DOI: 10.1186/s12936-014-0540-z
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The new protocol has the same efficacy as the standard one, but only a quarter of the duration, reducing dropout rates and side effects.
The initiative, carried out at the Consulate of Bolivia, has resulted in 307 new tests for the diagnosis of Chagas disease
The study shows that blocking the KLRG1 receptor helps to recover the activity of the natural killer cells of the immune system and reactivate the virus reservoir to fight infection.
