About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 35211799 Journal: PEDIATRIC NEPHROLOGY Year: 2022 Reference: Pediatr Nephrol. 2022 Feb 24. pii: 10.1007/s00467-022-05473-w. doi: 10.1007/s00467-022-05473-w. Impact factor: Publication type: Letter or abstract Authors: Abranches, M; Akman, S; Alpay, H; Ariceta, G; Atmis, B; Bael, A; Bakkaloglu, S A; Bakkaloglu, Sevcan A; Bayrakci, U S; Bhimma, R et al. DOI: 10.1007/s00467-022-05473-w
PMID: 35211308 Journal: Clinical Kidney Journal Year: 2022 Reference: Clin Kidney J. 2021 Nov 15;15(3):545-552. doi: 10.1093/ckj/sfab215. eCollection 2022 Mar. Impact factor: Publication type: Paper in international publication Authors: Abo, Anabel; Balius, Anna; Cruz, Alejandro; Fraga, Gloria; Gonzalez, Jorge; Jatem, Elias; Madrid, Alvaro; Martin, Marisa; Martinez, Cristina; Roca, Neus et al. DOI: 10.1093/ckj/sfab215
PMID: 35200058 Journal: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS Year: 2022 Reference: Int J Biol Markers. 2022 Jun;37(2):218-223. doi: 10.1177/03936155221081537. Epub 2022 Feb 24. Impact factor: Publication type: Paper in international publication Authors: Campistol, Miriam; Celma, Anna; de Torres, Ines; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Santamaria, Anna; Semidey, Maria E et al. DOI: 10.1177/03936155221081537
PMID: 33795596 Journal: TRANSPLANTATION Year: 2022 Reference: Transplantation. 2022 Mar 1;106(3):607-614. doi: 10.1097/TP.0000000000003771. Impact factor: Publication type: Paper in international publication Authors: Aufricht, Christoph; Battelino, Nina; Bjerre, Anna; Boehm, Michael; Bonthuis, Marjolein; de Jong, Huib; Edvardsson, Vidar O; Groothoff, Jaap; Harambat, Jerome; Herthelius, Maria et al. DOI: 10.1097/TP.0000000000003771
PMID: 33639975 Journal: Orphanet Journal of Rare Diseases Year: 2021 Reference: Orphanet J Rare Dis. 2021 Feb 27;16(1):104. doi: 10.1186/s13023-021-01729-0. Impact factor: Publication type: Paper in international publication Authors: Anton-Gamero, Montserrat; Ariceta, Gema; Carrasco Hidalgo-Barquero, Marta; Chocron, Sara; de la Cerda-Ojeda, Francisco; de Lucas-Collantes, Carmen; Espinosa, Laura; Fernandez-Escribano, Angustias; Fernandez-Fernandez, Marta; Fernandez-Maseda, M masculine Angeles et al. DOI: 10.1186/s13023-021-01729-0
PMID: 33623677 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Jan 17;14(2):543-549. doi: 10.1093/ckj/sfz173. eCollection 2021 Feb. Impact factor: Publication type: Paper in international publication Authors: Jatem, Elias; Martin, Maria Luisa; Martinez, Cristina; Molina, Maria; Munoz, Marina; Roca, Neus; Segarra, Alfons et al. DOI: 10.1093/ckj/sfz173
PMID: 33623672 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Aug 11;14(2):482-491. doi: 10.1093/ckj/sfaa110. eCollection 2021 Feb. Impact factor: Publication type: Review in international publication Authors: Agraz, Irene; Ariceta, Gema; Garcia-Carro, Clara; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Moreso, Francesc; Seron, Daniel; Soler, Maria Jose; Toapanta-Gaibor, Nestor; Vergara, Ander et al. DOI: 10.1093/ckj/sfaa110
PMID: 33597140 Journal: BMJ Open Year: 2021 Reference: BMJ Open. 2021 Feb 17;11(2):e043015. doi: 10.1136/bmjopen-2020-043015. Impact factor: Publication type: Paper in international publication Authors: Alper, Seth L; Ariceta, Gema; Aufricht, Christoph; Bakkaloglu, Sevcan; Cetin, Asil; Edefonti, Alberto; Eibensteiner, Fabian; Jankauskiene, Augustina; Klaus, Gunter; Paglialonga, Fabio et al. DOI: 10.1136/bmjopen-2020-043015
PMID: 30576809 Journal: GENE Year: 2019 Reference: Gene. 2019 Mar 20;689:227-234. doi: 10.1016/j.gene.2018.12.024. Epub 2018 Dec 18. Impact factor: Publication type: Paper in international publication Authors: Aguirre, Mireia; Ariceta, Gema; Claverie-Martin, Felix; Davitaia, Tinatin; Perdomo-Ramirez, Ana; Ramos-Trujillo, Elena et al. DOI: 10.1016/j.gene.2018.12.024
PMID: 30607568 Journal: PEDIATRIC NEPHROLOGY Year: 2019 Reference: Pediatr Nephrol. 2019 Jun;34(6):1077-1086. doi: 10.1007/s00467-018-4180-3. Epub 2019 Jan 4. Impact factor: Publication type: Paper in international publication Authors: Anton-Gamero, Montserrat; Ariceta, Gema; Chocron, Sara; de la Cerda Ojeda, Francisco; Fernandez-Fernandez, Marta; Fernandez-Maseda, Angeles; Ferrando-Monleon, Susana; Gil-Pena, Helena; Gonzalez-Sanchez, Susana; Hernandez-Frias, Olaya et al. DOI: 10.1007/s00467-018-4180-3
PMID: 31807296 Journal: Clinical Kidney Journal Year: 2019 Reference: Clin Kidney J. 2019 Mar 16;12(6):836-839. doi: 10.1093/ckj/sfz022. eCollection 2019 Dec. Impact factor: 2.975 Publication type: Paper in international publication Authors: Roca, Neus, Munoz, Marina, Cruz, Alejandro, Vilalta, Ramon, Lara, Enrique, Ariceta, Gema et al. DOI: 10.1093/ckj/sfz022
PMID: 31611066 Journal: KIDNEY INTERNATIONAL Year: 2019 Reference: Kidney Int. 2019 Dec;96(6):1374-1380. doi: 10.1016/j.kint.2019.06.026. Epub 2019 Aug 14. Impact factor: 8.306 Publication type: Paper in international publication Authors: Porrini, Esteban, Diaz, Juan Manuel, Moreso, Francesc, Lauzurrica, Ricardo, Ibernon, Meritxel, Torres, Irene Silva, Ruiz, Rocio Benitez, Rodriguez Rodriguez, Ana Elena, Mallen, Patricia Delgado, Bayes-Genis, Beatriz et al. DOI: 10.1016/j.kint.2019.06.026
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
