About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
Biòpsia liquida en carcinoma hepatocel·lular
Biomarcadors de carcinoma hepatocel·lular
Efectes de la suplementació del Zinc en models preclínics de carcinoma hepatocel·lular
Assaigs clínics per carcinoma hepatocel·lular
IP: Beatriz Minguez Rosique
Trombosis portal
Malalties vasculars porto-sinusoïdals
Hipertensió portal
Encefalopatia hepàtica
IP: Macarena Simon-Talero Horga
Subtipat i resistències del virus de la hepatitis C
Quasispècies del virus de la hepatitis E
Exosomes hepàtics en malalties hepàtiques i tumors hepàtics
Identificació, caracterització i variabilitat d’agents virals per seqüenciació massiva, Next Generation Sequencing (NGS)
Serveis o tecnologies rellevants
Seqüenciació Sanger i massiva (NGS)
Extracció i amplificació àcids nucleics
Filogènia molecular disseny primers
Tècniques de Biologia Molecular
Gradients per aïllament i estudi d'exosomes en plasma i femta
Citometria de Flux
Resposta immune cel·lular
Cultius
Clonació, expressió de proteïnes recombinants en cultius cel·lulars
Bioinformàtica
IP: Juan Ignacio Esteban Mur, Josep Quer Sivila
Resposta immune en pacients amb hepatitis crònica B (HBeAg negatius)
Marcadors serològics i virològics per monitoritzar la infecció crònica per VHB i VHD
Mecanismes d'interacció entre VHB i VHD
Estudis fenotípics in vitro en models de transfecció o infecció del VHB i VHD
Virus de la hepatitis E
Eliminació del virus de la hepatitis C en poblacions d' alta prevalença
Mecanismes fisiopatològics de la hepatitis autoimmune
Hepatitis immunomediadas per inhibidors de checkpoint oncològics
Serveis o tecnologies rellevants:
Estudi de les quasispècies dels virus VHB i VHD per seqüenciació massiva
IP: Maria Buti Ferret, Maria del Mar Riveiro Barciela
IP: Maria Buti Ferret Collaborators: Adriana Palom Agusti Funding agency: Gilead Sciences, Inc. Funding: Reference: GILEAD/SPEARHEAD/2023/BUTI_OPTI-HEPD Duration: 01/01/2024 - 30/06/2025
IP: Beatriz Minguez Rosique Collaborators: Agnès Soriano Varela, Concepción Gomez Gavara Funding agency: Asociación Española Contra el Cáncer Funding: 41000 Reference: RETOS245779LLOV Duration: 01/07/2024 - 30/11/2030
IP: Arnau Llauradó Gayete Collaborators: Josep Quer Sivila, Laura Costa Comellas Funding agency: Instituto de Salud Carlos III Funding: 480370 Reference: PMPER24/00018 Duration: 01/01/2025 - 31/12/2026
IP: Maria Buti Ferret Collaborators: Adriana Palom Agusti, Jordi Gómez i Prat, Hakima Ouaarab Essadek Funding agency: Gilead Sciences, S.L.U. Funding: 46416 Reference: GLD24/00062 Duration: 27/02/2025 - 27/08/2026
PhD student: Anna Feliu Prius Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela University: Universitat Autònoma de Barcelona Year: 2024
PhD student: Cesar Jimenez Hernandez Director/s: Victor Manuel Vargas Blasco University: Universitat Autònoma de Barcelona Year: 2024
PhD student: Ana Barreira Diaz, Ana Barreira Diaz Director/s: Fernando Martínez Valle, Maria del Mar Riveiro Barciela University: Year: 2024
PhD student: Maria luisa Roade Tato Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela University: Year: 2024
PhD student: Cristina Marcos Fosch Director/s: Maria Buti Ferret University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Mar Gil Soler Director/s: Maria Nieves Martell Pérez-Alcalde, Diana Hide Alferez University: Universidad Autònoma de Barcelona Year: 2023
PhD student: Aurora Barbera Belles Director/s: Maria Nieves Martell Pérez-Alcalde, Salvador Augustin Recio University: Universidad Autònoma de Barcelona Year: 2023
PhD student: Meritxell Llorens Revull Director/s: Josep Quer Sivila, Marta Bes Maijo, Celia Belen Perales Viejo University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Adriana Palom Agusti, Adriana Palom Agusti Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela University: Universitat Autònoma de Barcelona Year: 2022
PhD student: Jordi Llaneras Artigues Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela University: Universitat Autònoma de Barcelona Year: 2022
PhD student: IRENE CONEJO SOSA Director/s: Salvador Augustin Recio University: Universidad Autònoma de Barcelona Year: 2021
PhD student: Sofia Romina Piriz Ruzo Director/s: Josep Quer Sivila, Maria Buti Ferret, Francisco Rodríguez Frias University: Universidad Autònoma de Barcelona Year: 2021
PhD student: Miren Bravo Garmendia Director/s: Maria Nieves Martell Pérez-Alcalde, Joan Genescà Ferrer University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Sara Sopena Santisteve Director/s: Maria Buti Ferret, David Tabernero Caellas, David Tabernero Caellas University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Mònica Pons Delgado Director/s: Joan Genescà Ferrer, Salvador Augustin Recio University: Universidad Autònoma de Barcelona Year: 2019
PhD student: Eider Talavera Urquijo, Eider Talavera Urquijo Director/s: José Maria Balibrea del Castillo, Maria Nieves Martell Pérez-Alcalde, Salvador Augustin Recio University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Qian Chen Director/s: Josep Quer Sivila, Celia Belen Perales Viejo, Josep Gregori Font University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Teresa García Lezana Director/s: Salvador Augustin Recio, Laia Chavarria Vilarasau, Joan Genescà Ferrer University: Universidad Autònoma de Barcelona Year: 2017
PhD student: Andrea Caballero Garralda Director/s: Maria Buti Ferret, Francisco Rodríguez Frias University: Universidad Autònoma de Barcelona Year: 2016
PhD student: David Tabernero Caellas, David Tabernero Caellas Director/s: Maria Buti Ferret, Francisco Rodríguez Frias University: Universidad Autònoma de Barcelona Year: 2015
PhD student: Isabel Campos Varela Director/s: Juan Ignacio Esteban Mur, Lluis Castells Fusté, Juan Ignacio Esteban Mur University: Universidad Autònoma de Barcelona Year: 2013
PhD student: Maria Homs Riba Director/s: Maria Buti Ferret, Francisco Rodríguez Frias University: Universidad Autònoma de Barcelona Year: 2012
PhD student: Salvador Augustin Recio Director/s: Joan Genescà Ferrer University: Universidad Autònoma de Barcelona Year: 2011
PhD student: Beatriz Minguez Rosique Director/s: University: Universidad Autònoma de Barcelona Year: 2007
Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research
This tool will help avoid invasive techniques and assist in selecting candidates for clinical trials of new treatments.
The meetings served to share advances in translational research and consolidate international scientific alliances in the study of liver diseases
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
