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Molecular Medical Imaging

The Molecular Medical Imaging research group focuses its activity on deepening the molecular bases and developing new areas of research in molecular signaling pathways and the identification of new theranostic targets.

We promote the confluence of basic and clinical researchers, experts in imaging and molecular biology to provide:

  • Access to knowledge of the biokinetics and biodistribution of the molecules under study
  • The proofs of concept necessary in the research processes
  • The identification and quantification of the targets defined by the research groups of our center

In this context, the creation of a translational imaging unit constitutes a basic objective for the development of research aimed at the personalized treatment of patients.

The group is made up of medical specialists in molecular imaging, chemists and pharmacists specializing in tracer synthesis, and biomedical engineers and physicists specializing in image processing and tomography equipment. These are affiliated with different institutions, such as the Vall d'Hebron Research Institute (VHIR), the Vall d'Hebron University Hospital (HUVH) and the Institute of Diagnostic Imaging (IDI).

Team

Alvaro Jesus Valverde Moya

Alvaro Jesus Valverde Moya

Predoctoral researcher
Molecular Medical Imaging
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Amparo García Burillo

Amparo García Burillo

Molecular Medical Imaging
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Ana Maria Rodriguez Arana

Ana Maria Rodriguez Arana

Main researcher
Molecular Medical Imaging
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Andreu Antolin Redondo

Andreu Antolin Redondo

Predoctoral researcher
Molecular Medical Imaging
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Carles Lorenzo Bosquet

Carles Lorenzo Bosquet

Molecular Medical Imaging
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Carmen Sanchez Suarez

Carmen Sanchez Suarez

Molecular Medical Imaging
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Alvaro Jesus Valverde Moya

Alvaro Jesus Valverde Moya

Predoctoral researcher
Molecular Medical Imaging
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Amparo García Burillo

Amparo García Burillo

Molecular Medical Imaging
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Ana Maria Rodriguez Arana

Ana Maria Rodriguez Arana

Main researcher
Molecular Medical Imaging
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Andreu Antolin Redondo

Andreu Antolin Redondo

Predoctoral researcher
Molecular Medical Imaging
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Carles Lorenzo Bosquet

Carles Lorenzo Bosquet

Molecular Medical Imaging
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Carmen Sanchez Suarez

Carmen Sanchez Suarez

Molecular Medical Imaging
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Projects

Insulin resistance in type 2 diabetes: unraveling the pathogenic mechanism between organs

IP: José Raul Herance Camacho
Collaborators: Fiorella Dellepiane Clarke, Joan Castell Conesa, Santiago Aguade Bruix, Carina Espinet Coll, Nuria Roson Gradaille, Carolina Aparicio Gomez, Alberto Roque Pérez, Mònica Velasco Nuño, Julia Baguña Torres, Irene Hernández Hernández, Maria Nazarena Pizzi
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI20/01588
Duration: 01/01/2021 - 30/06/2025

The Vall d’Hebron Iniciative for Parkinson associated to GBA (VHIP-GBA): from biospecimen collection to translational studies and therapies.

IP: Marta Martínez Vicente
Collaborators: José Antonio Arranz Amo, Jorge Hernández Vara, Eddie Pradas Gracia, Guillem Pintos Morell, Clara Carnicer Cáceres, Carles Lorenzo Bosquet, David Moreno Martinez, Jordi Riera Heredia, Marta Montpeyó Garcia-Moreno, Daniela Samaniego Toro, Laura Castillo Ribelles
Funding agency: Instituto de Salud Carlos III
Funding: 245932.5
Reference: PI20/00728
Duration: 01/01/2021 - 30/06/2025

Role of sarcopenia in the evolution of morbidly obese patients who undergo bariatric surgery. Study of cohorts and mechanisms involved.

IP: Andreea Ciudin Mihai
Collaborators: Oscar González López, Fiorella Ximena Palmas Candia, Marina Giralt Arnaiz, Marta Comas Martínez, Rosa Burgos Peláez, Irene Hernández Hernández, Enzamaría Fidilio Meli, Efráin Santiago Cordero Vázquez, Cristina Gamez Cenzano
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI20/01086
Duration: 01/01/2021 - 31/12/2024

Characterization of the CD8 T cell response in Parkinson’s disease for the development of preventive and therapeutic strategies that halt the progression of the disease: SARS-Cov-2-induced long term-hyposmia as a possible prodromal stage

IP: Jordi Bove Badell
Collaborators: Miquel Vila Bover, Alejandro Ferré Masó, Oriol de Fabregues-Boixar Nebot, Carles Lorenzo Bosquet, Thais Cuadros Arasa, Antonio Palasi Franco, David Ramos Vicente, Mariona Marchena Herrera
Funding agency: Instituto de Salud Carlos III
Funding: 165770
Reference: PI21/01358
Duration: 01/01/2022 - 31/12/2024

Publications

Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden.

PMID: 37939322
Journal: Brain and Behavior
Year: 2023
Reference: Brain Behav. 2023 Nov 8:e3295. doi: 10.1002/brb3.3295.
Impact factor:
Publication type: Paper in international publication
Authors: Ahmed, S F; Albano, D; Alonso Losada, Maria G; Alonso Redondo, Ruben; Alvarado, Maria Cristina Iniguez; Alvarez Sauco, Maria; Avila Rivera, Maria A; Borrue, Carmen; Buongiorno, Maria Teresa; Caballol, Nuria et al.
DOI: 10.1002/brb3.3295

Vall d'Hebron Risk Score II for myocardial infarction and cardiac death.

PMID: 37935561
Journal:
Year: 2023
Reference: Open Heart. 2023 Nov;10(2):e002431. doi: 10.1136/openhrt-2023-002431.
Impact factor:
Publication type: Paper in international publication
Authors: Aguade-Bruix, Santiago; Aterido, A; Carrascosa-Carrillo, J M; Ferreira Gonzalez, Ignacio; Guillen, Y; Julia, A; Li, T; Marsal, S; Martinez, S; Romero-Farina, Guillermo et al.
DOI: 10.1136/openhrt-2023-002431

A low total metabolic tumor volume independently predicts for a longer time to first treatment in initially observed, low tumor burden follicular lymphoma.

PMID: 37942762
Journal: HEMATOLOGICAL ONCOLOGY
Year: 2023
Reference: Hematol Oncol. 2023 Nov 9. doi: 10.1002/hon.3235.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Aguade-Bruix, Santiago; Campo, Elias; Casanueva-Eliceiry, Sebastian; Correa, Juan Gonzalo; Delgado, Julio; Ferreira Gonzalez, Ignacio; Gine, Eva; Gomez-Hernando, Marta; Guinetti-Ortiz, Katia et al.
DOI: 10.1002/hon.3235

Accuracy of a sequential algorithm based on FIB-4 and ELF to identify high-risk advanced liver fibrosis at the primary care level.

PMID: 37952070
Journal: Internal and Emergency Medicine
Year: 2023
Reference: Intern Emerg Med. 2023 Nov 11. doi: 10.1007/s11739-023-03441-2.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Augustin, Salvador; Campo, Elias; Casanueva-Eliceiry, Sebastian; Ciudin, Andreea; Correa, Juan Gonzalo; Delgado, Julio; Ferrer-Costa, Roser; Gabriel-Medina, Pablo; Gine, Eva et al.
DOI: 10.1007/s11739-023-03441-2

Cancer screening in idiopathic inflammatory myopathies: Ten years experience from a single center.

PMID: 35051890
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2022
Reference: Semin Arthritis Rheum. 2022 Apr;53:151940. doi: 10.1016/j.semarthrit.2021.12.008. Epub 2021 Dec 31.
Impact factor: 5.532
Publication type: Paper in international publication
Authors: Trallero-Araguas, Ernesto, Gil-Vila, Albert, Martinez-Gomez, X, Pinal-Fernandez, Iago, Alvarado-Cardenas, M, Simo-Perdigo, M, Selva-O'Callaghan, Albert et al.
DOI: 10.1016/j.semarthrit.2021.12.008

Usefulness of the FDG PET/CT in the management of cystic echinococcosis: a pilot study.

PMID: 34954257
Journal: ACTA TROPICA
Year: 2022
Reference: Acta Trop. 2022 Mar;227:106295. doi: 10.1016/j.actatropica.2021.106295. Epub 2021 Dec 24.
Impact factor: 3.112
Publication type: Paper in international publication
Authors: Molina, Israel, Espinosa-Pereiro, Juan, Bosch-Nicolau, Pau, Simo, Marc, Salvador, Fernando, Escola-Verge, Laura, Barios, Marta, Belhassen-Garcia, Moncef, Tamayo-Alonso, Pilar, Sanchez-Montalva, Adrian et al.
DOI: 10.1016/j.actatropica.2021.106295

CT or Invasive Coronary Angiography in Stable Chest Pain.

PMID: 35240010
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2022
Reference: N Engl J Med. 2022 Apr 28;386(17):1591-1602. doi: 10.1056/NEJMoa2200963. Epub 2022 Mar 4.
Impact factor: 91.253
Publication type: Paper in international publication
Authors: Rieckmann, Nina, Maurovich-Horvat, Pal, Bosserdt, Maria, Kofoed, Klaus F, Merkely, Bela, Knudsen, Andreas D, Benedek, Imre, Orr, Clare, Xavier Valente, Filipa, Zvaigzne, Ligita et al.
DOI: 10.1056/NEJMoa2200963

The current state of knowledge on imaging informatics: a survey among Spanish radiologists.

PMID: 35235068
Journal: Insights into Imaging
Year: 2022
Reference: Insights Imaging. 2022 Mar 2;13(1):34. doi: 10.1186/s13244-022-01164-0.
Impact factor: 5.231
Publication type: Paper in international publication
Authors: Eiroa, Daniel, Antolin, Andreu, Fernandez Del Castillo Ascanio, Monica, Pantoja Ortiz, Violeta, Escobar, Manuel, Roson, Nuria et al.
DOI: 10.1186/s13244-022-01164-0

Substrate characterization of right ventricle in repaired tetralogy of Fallot using late enhancement cardiac magnetic resonance.

PMID: 34098087
Journal: HEART RHYTHM
Year: 2021
Reference: Heart Rhythm. 2021 Nov;18(11):1868-1875. doi: 10.1016/j.hrthm.2021.05.032. Epub 2021 Jun 19.
Impact factor: 6.343
Publication type: Paper in international publication
Authors: Rodriguez-Palomares, Jose, Rivas-Gandara, Nuria, Dos-Subira, Laura, Francisco-Pascual, Jaume, Rodriguez-Garcia, Julian, Pijuan-Domenech, Antonia, Benito, Begona, Valente, Filipa, Pascual-Gonzalez, Gabriel, Santos-Ortega, Alba et al.
DOI: 10.1016/j.hrthm.2021.05.032

Corticobasal syndrome: A case of discordance between the clinical findings and the imaging biomarkers.

PMID: 33875401
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2021 Apr 16. pii: S2253-654X(21)00057-3. doi: 10.1016/j.remn.2021.02.015.
Impact factor: 1.359
Publication type: Letter or abstract
Authors: Hernandez-Vara, J, Martinez-Saez, E, Lucas Del Pozo, S, Cardozo-Saavedra, A, Carrillo-Villamizar, E, Lorenzo-Bosquet, C et al.
DOI: 10.1016/j.remn.2021.02.015

Intraventricular Conundrum in a SARS-CoV-2-Positive Patient With Elevated Biomarkers of Myocardial Injury.

PMID: 33821246
Journal: JACC. Case reports
Year: 2021
Reference: JACC Case Rep. 2021 Apr;3(4):566-572. doi: 10.1016/j.jaccas.2021.01.030. Epub 2021 Mar 31.
Impact factor: 0
Publication type: Letter or abstract
Authors: Burcet, Gemma, Teixido-Tura, Gisela, Calabria, Hug Cuellar, Gonzalez, Ignacio Ferreira, Rodriguez-Palomares, Jose F, Fernandez-Galera, Ruben, Casas, Guillem, Valente, Filipa X, Servato, Maria L, Garcia-Moreno, Laura Gutierrez et al.
DOI: 10.1016/j.jaccas.2021.01.030

Active bleeding after kidney biopsy: Successful ultrasound-guided direct thrombin embolization into the cortical fistula.

PMID: 33098132
Journal: JOURNAL OF CLINICAL ULTRASOUND
Year: 2021
Reference: J Clin Ultrasound. 2021 May;49(4):390-394. doi: 10.1002/jcu.22939. Epub 2020 Oct 24.
Impact factor: 0.91
Publication type: Letter or abstract
Authors: Escudero-Fernandez, Jose Miguel, Bolufer Cardona, Monica, Perez Lafuente, Mercedes, Montealegre, Carolina, Uriarte, Iciar, Serres-Creixams, Xavier et al.
DOI: 10.1002/jcu.22939

Mosaic Bioprostheses May Mimic Infective Endocarditis by PET/CTA: Trust the Uptake Pattern to Avoid Misdiagnosis.

PMID: 31954645
Journal: JACC-Cardiovascular Imaging
Year: 2020
Reference: JACC Cardiovasc Imaging. 2020 Oct;13(10):2239-2244. doi: 10.1016/j.jcmg.2019.11.019. Epub 2020 Jan 15.
Impact factor: 12.74
Publication type: Paper in international publication
Authors: Cuellar-Calabria, Hug, Tornos, Pilar, Roque, Albert, Pizzi, Maria N, Fernandez-Hidalgo, Nuria, Gonzalez-Alujas, Maria Teresa, Rios, Remedios, Castell-Conesa, Joan, Escobar, Manuel, Ferreira-Gonzalez, Ignacio et al.
DOI: 10.1016/j.jcmg.2019.11.019

Morpho-metabolic post-surgical patterns of non-infected prosthetic heart valves by [18F]FDG PET/CTA: "normality" is a possible diagnosis.

PMID: 31539031
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2020
Reference: Eur Heart J Cardiovasc Imaging. 2020 Jan 1;21(1):24-33. doi: 10.1093/ehjci/jez222.
Impact factor: 4.841
Publication type: Paper in international publication
Authors: Fernandez-Hidalgo, Nuria, Permanyer, Eduard, Cuellar-Calabria, Hug, Romero-Farina, Guillermo, Rios, Remedios, Almirante, Benito, Castell-Conesa, Joan, Escobar, Manuel, Ferreira-Gonzalez, Ignacio, Tornos, Pilar et al.
DOI: 10.1093/ehjci/jez222

Percutaneous ultrasound guided vacuum-assisted excision of benign breast lesions: A learning curve to assess outcomes.

PMID: 30359092
Journal: BRITISH JOURNAL OF RADIOLOGY
Year: 2019
Reference: Br J Radiol. 2019 Feb;92(1094):20180626. doi: 10.1259/bjr.20180626. Epub 2018 Nov 29.
Impact factor: 1.939
Publication type: Paper in international publication
Authors: Salazar, Juan Pablo, Miranda, Ignacio, de Torres, Juan, Rus, Maria N, Espinosa-Bravo, Martin, Esgueva, Antonio, Salvador, Rafael, Rubio, Isabel T et al.
DOI: 10.1259/bjr.20180626

Utility of the (18)F-Florbetapir positron emission tomography in systemic amyloidosis.

PMID: 29706127
Journal: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
Year: 2018
Reference: Amyloid. 2018 Jun;25(2):109-114. doi: 10.1080/13506129.2018.1467313. Epub 2018 Apr 28.
Impact factor: 4.048
Publication type: Paper in international publication
Authors: Lorenzo-Bosquet, Carles, Mestre-Torres, Jaume, Solans-Laque, Roser, Fernandez-Codina, Andreu, Bujan-Rivas, Segundo, Castell-Conesa, Joan, Martinez-Valle, Fernando, Gironella, Mercedes, Cuberas-Borros, Gemma et al.
DOI: 10.1080/13506129.2018.1467313

Revascularization experience and results in ischaemic cerebrovascular disease: Moyamoya disease and carotid occlusion.

PMID: 29550248
Journal: NEUROCIRUGIA
Year: 2018
Reference: Neurocirugia (Astur). 2018 Jul - Aug;29(4):170-186. doi: 10.1016/j.neucir.2018.01.006. Epub 2018 Mar 14.
Impact factor: 0.31
Publication type: Paper in national publication
Authors: Arikan, Fuat, Rubiera, Marta, Serena, Joaquin, Rodriguez-Hernandez, Ana, Gandara, Dario, Lorenzo-Bosquet, Carles, Tomasello, Alejandro, Chocron, Ivette, Quintana-Corvalan, Maximiliano, Sahuquillo, Juan et al.
DOI: 10.1016/j.neucir.2018.01.006

Computed Tomography Aortic Valve Calcium Scoring in Patients With Aortic Stenosis.

PMID: 29555836
Journal: Circulation-Cardiovascular Imaging
Year: 2018
Reference: Circ Cardiovasc Imaging. 2018 Mar;11(3):e007146. doi: 10.1161/CIRCIMAGING.117.007146.
Impact factor: 6.221
Publication type: Paper in international publication
Authors: Evangelista, Arturo, Pawade, Tania, Clavel, Marie-Annick, Tribouilloy, Christophe, Dreyfus, Julien, Mathieu, Tiffany, Tastet, Lionel, Renard, Cedric, Gun, Mesut, Jenkins, William Steven Arthur et al.
DOI: 10.1161/CIRCIMAGING.117.007146

Interarterial Coronary Tract: Presumptive Echocardiographic Diagnosis.

PMID: 29030204
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2018
Reference: Rev Esp Cardiol (Engl Ed). 2018 Mar;71(3):205. doi: 10.1016/j.rec.2017.08.002. Epub 2017 Oct 10.
Impact factor: 5.166
Publication type: Paper in national publication
Authors: Dolader, Paola, Cuellar, Hug, Albert, Dimpna C et al.
DOI: 10.1016/j.rec.2017.08.002

Assessment of amyloid deposits by F-florbetapir positron emission tomography.

PMID: 26081942
Journal: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Year: 2015
Reference: Eur J Nucl Med Mol Imaging. 2015 Oct;42(11):1778-1779. doi: 10.1007/s00259-015-3108-4. Epub 2015 Jun 17.
Impact factor: 5.383
Publication type: Paper in international publication
Authors: Martinez-Valle, Fernando, Gironella, Mercedes, Riveiro-Barciela, Mar, Lorenzo-Bosquet, Carles et al.
DOI: 10.1007/s00259-015-3108-4

[SPECT, coronary angio-CT, invasive coronary angiography and fusion images in stable coronary disease].

PMID: 25555322
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2015
Reference: Rev Esp Med Nucl Imagen Mol. 2015 May-Jun;34(3):173-80. doi: 10.1016/j.remn.2014.11.004. Epub 2014 Dec 30.
Impact factor: 1.054
Publication type: Paper in national publication
Authors: Pizzi, M N, Aguade-Bruix, S, Roque, A, Romero-Farina, G, Garcia del Blanco, B, Castell-Conesa, J, Garcia-Dorado, D, Candell-Riera, J, Cuellar-Calabria, H et al.
DOI: 10.1016/j.remn.2014.11.004

Blog

News

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

Phase IV AI is included in the Horizon Europe programme, lasts 3 years and prioritises data security and privacy compliance.

YSOTOPE, a DeepTech start-up with the mission to improve the use of immunotherapies through medical imaging, became part of the spin-off network of VHIR and successfully closed its first investment round of €150,000 with Biozell Ventures.

Job offers

Data Analyst and Project Manager
Start date:
24/05/2023
End date:
07/06/2023
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LABORATORY TECHNICIAN position in PET imaging - Medical Molecular Imaging Research Group
Start date:
16/09/2022
End date:
30/09/2022
Document: Download
Postdoctoral position to develop radiopharmaceuticals targeting glioblastoma
Start date:
12/07/2022
End date:
31/07/2022
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