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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Projects

Estudio de la eficacia inmunosupresora de una nueva proteína de fusión dual Hybri-2 que bloquea las señales de co-estimulación a nivel de CD28/CD80-CD86 y PDL2/PD1 con el fin de inhibir la respuesta de memoria humoral y dar acceso al trasplante en pa

IP: Oriol Bestard Matamoros
Collaborators: Elena Isabel Crespo Gimeno, Maria Antonia Emilia Meneghini
Funding agency: Fundación Renal Iñigo Alvarez de Toledo
Funding: 105699.31
Reference: FRIAT/PROJECTES/2019/BESTARD
Duration: 01/04/2020 - 31/03/2024

HORUS: Casting light on HOst-cytomegaloviRUs interaction in Solid organ transplantation

IP: Oriol Bestard Matamoros
Collaborators: Elena Isabel Crespo Gimeno
Funding agency: EUROPEAN COMMISSION
Funding: 392651.25
Reference: HORUS_HE-HLTH-DISEASE21
Duration: 01/11/2022 - 31/10/2027

VALIDATE: Validation of a Trustworthy AI-based Clinical Decision Support System for Improving Patient Outcome in Acute Stroke Treatment

IP: Marta Aurora Rubiera Del Fueyo
Collaborators: Maria Victoria Sala Sanz de Madrid, Cristina Guirao Martinez, Claudia Meza Burgos, Federica Rizzo, Ester Sanchez Gavilan, David Rodriguez Luna
Funding agency: EUROPEAN COMMISSION
Funding: 567950
Reference: VALIDATE_HE-HLTH-DISEASE21
Duration: 01/05/2022 - 30/04/2026

AGORA - Algoritmo de evolución del injerto en trasplante renal

IP: Oriol Bestard Matamoros
Collaborators: Emma Pardo De los Santos, Elena Isabel Crespo Gimeno, Maria Antonia Emilia Meneghini, Franc Casanova Ferrer, Mariona Juvé Torres
Funding agency: Instituto de Salud Carlos III
Funding: 154033
Reference: AC21_2/00050
Duration: 01/01/2022 - 31/12/2025

Blog

News

The distinction from the Catalan Transplant Society will allow her to become a member of the Royal Academy of Medicine of Catalonia.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.