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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

SARS-CoV-2 infection in patients with chronic kidney disease on haemodialysis. Evolution of SARS-CoV-2 CRP.

PMID: 33632558
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia. 2021 Jul-Aug;41(4):476-478. doi: 10.1016/j.nefro.2020.12.008. Epub 2021 Jan 28.
Impact factor: 2.033
Publication type: Letter or abstract
Authors: Zuniga, Jose, Toapanta, Nestor, Ramos, Natalia, Caparros, Sonia, Leon-Roman, Juan, Azancot, Maria, Garcia-Carro, Clara, Espinel, Eugenia, Seron, Daniel, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2020.12.008

Challenges in primary focal segmental glomerulosclerosis diagnosis: from the diagnostic algorithm to novel biomarkers.

PMID: 33623672
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2020 Aug 11;14(2):482-491. doi: 10.1093/ckj/sfaa110. eCollection 2021 Feb.
Impact factor: 4.452
Publication type: Review in international publication
Authors: Toapanta-Gaibor, Nestor, Ariceta, Gema, Moreso, Francesc, Seron, Daniel, Lopez-Hellin, Joan, Soler, Maria Jose, Agraz, Irene, Garcia-Carro, Clara, Jacobs-Cacha, Conxita, Vergara, Ander et al.
DOI: 10.1093/ckj/sfaa110

Change in Estimated GFR and Risk of Allograft Failure in Patients Diagnosed With Late Active Antibody-mediated Rejection Following Kidney Transplantation.

PMID: 33617203
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Mar 1;105(3):648-659. doi: 10.1097/TP.0000000000003274.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Djamali, Arjang, Irish, William, Nickerson, Peter, Astor, Brad C, Chong, Edward, Wiebe, Chris, Moreso, Francesc, Seron, Daniel, Crespo, Marta, Gache, Larry et al.
DOI: 10.1097/TP.0000000000003274

Paternal safety of the use of Mycophenolic Acid in kidney transplant recipients. Results of the EMVARON study.

PMID: 33599030
Journal: CLINICAL TRANSPLANTATION
Year: 2021
Reference: Clin Transplant. 2021 May;35(5):e14256. doi: 10.1111/ctr.14256. Epub 2021 Feb 27.
Impact factor: 2.863
Publication type: Paper in international publication
Authors: Jimenez, C, Perez-Mir, M, Martin-Moreno, P L, Sanchez-Fructuoso, A I, Mir, M, Lopez-Lopez, I, Gonzalez-Rinne, A, Coca, A, Valero, R, Ventura Galiano, A et al.
DOI: 10.1111/ctr.14256

Blog

News

A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.

An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.

Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.