About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
IP: Oriol Bestard Matamoros Collaborators: Emma Pardo De los Santos, Elena Isabel Crespo Gimeno, Maria Antonia Emilia Meneghini Funding agency: Instituto de Salud Carlos III Funding: 154033 Reference: AC21_2/00050 Duration: 01/01/2022 - 31/12/2024
PMID: 35265335 Journal: Clinical Kidney Journal Year: 2022 Reference: Clin Kidney J. 2021 Jul 10;15(1):5-13. doi: 10.1093/ckj/sfab131. eCollection 2022 Jan. Impact factor: 4.452 Publication type: Review in international publication Authors: Montero, Nuria, Oliveras, Laia, Soler, Maria Jose, Cruzado, Josep Maria et al. DOI: 10.1093/ckj/sfab131
PMID: 35268550 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Mar 7;11(5). pii: jcm11051459. doi: 10.3390/jcm11051459. Impact factor: 4.242 Publication type: Paper in international publication Authors: Mast, Richard, Vergara, Ander, Agraz, Irene, Leon, Juan Carlos, Bolufer, Monica, Gabaldon, Maria-Alejandra, Seron, Daniel, Bestard, Oriol, Soler, Maria Jose, Garcia-Carro, Clara et al. DOI: 10.3390/jcm11051459
PMID: 34851532 Journal: CLINICAL TRANSPLANTATION Year: 2022 Reference: Clin Transplant. 2022 Mar;36(3):e14550. doi: 10.1111/ctr.14550. Epub 2021 Dec 17. Impact factor: 2.863 Publication type: Paper in international publication Authors: Andres, Amado, Rivera, Constantino Fernandez, Rodriguez, Maria Calvo, Poveda, Jose Luis, Pascual, Julio, Crespo, Marta, Gomez, Gonzalo, Pelegrin, Sheila Cabello, Paul, Javier, Lauzurica, Ricardo et al. DOI: 10.1111/ctr.14550
PMID: 33150431 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Feb 25;37(3):409-420. doi: 10.1093/ndt/gfaa219. Impact factor: 5.992 Publication type: Paper in international publication Authors: Malyszko, Jolanta, Basak, Grzegorz, Batko, Krzysztof, Capasso, Giavambatista, Drozd-Sokolowska, Joanna, Krzanowska, Katarzyna, Kulicki, Pawel, Matuszkiewicz-Rowinska, Joanna, Soler, Maria Jose Romeo, Sprangers, Ben et al. DOI: 10.1093/ndt/gfaa219
PMID: 34069888 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 May 18;10(10). pii: jcm10102174. doi: 10.3390/jcm10102174. Impact factor: 4.242 Publication type: Paper in international publication Authors: Agraz, Irene, Moreso, Francesc, Soler, Maria Jose, Seron, Daniel, Lopez-Hellin, Joan, Villena-Ortiz, Yolanda, Sellares, Joana, Vergara, Ander, Jacobs-Cacha, Conxita, Puig-Gay, Natalia et al. DOI: 10.3390/jcm10102174
PMID: 34072230 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 May 27;10(11). pii: jcm10112364. doi: 10.3390/jcm10112364. Impact factor: 4.242 Publication type: Review in international publication Authors: Delgado, Pilar, Soler, Maria Jose, Pujadas, Francesc, Maisterra, Olga, Jimenez-Balado, Joan, Ariton, Diana Maria et al. DOI: 10.3390/jcm10112364
PMID: 33340043 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Jan 1;36(1):87-94. doi: 10.1093/ndt/gfaa314. Impact factor: 5.992 Publication type: Paper in international publication Authors: Ortiz, Alberto, Cozzolino, Mario, Fliser, Danilo, Fouque, Denis, Goumenos, Dimitrios, Massy, Ziad A, Rosenkranz, Alexander R, Rychlik, Ivan, Soler, Maria Jose, Stevens, Kate et al. DOI: 10.1093/ndt/gfaa314
PMID: 33339673 Journal: NEFROLOGIA Year: 2021 Reference: Nefrologia. 2021 May-Jun;41(3):237-243. doi: 10.1016/j.nefro.2020.09.004. Epub 2020 Dec 16. Impact factor: 2.033 Publication type: Review in national publication Authors: Pascual, Julio, Rodriguez Manas, Leocadio, Perez-Saez, Maria Jose, Gutierrez-Dalmau, Alex, Moreso, Francesc et al. DOI: 10.1016/j.nefro.2020.09.004
PMID: 32076718 Journal: CLINICAL INFECTIOUS DISEASES Year: 2020 Reference: Clin Infect Dis. 2020 Dec 3;71(9):2375-2385. doi: 10.1093/cid/ciz1209. Impact factor: 8.313 Publication type: Paper in international publication Authors: Cruzado, Josep M, Jarque, Marta, Crespo, Elena, Melilli, Edoardo, Gutierrez, Alex, Moreso, Francesc, Guirado, Lluis, Revuelta, Ignacio, Montero, Nuria, Torras, Joan et al. DOI: 10.1093/cid/ciz1209
PMID: 32046355 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Feb 8;9(2). pii: jcm9020472. doi: 10.3390/jcm9020472. Impact factor: 3.303 Publication type: Review in international publication Authors: Garcia-Fernandez, Nuria, Jacobs-Cacha, Conxita, Mora-Gutierrez, Jose Maria, Vergara, Ander, Orbe, Josune, Soler, Maria Jose et al. DOI: 10.3390/jcm9020472
PMID: 31869590 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2020 Reference: J Neurol Sci. 2020 Feb 15;409:116635. doi: 10.1016/j.jns.2019.116635. Epub 2019 Dec 14. Impact factor: 3.115 Publication type: Paper in international publication Authors: Jimenez-Balado, Joan, Riba-Llena, Iolanda, Pizarro, Jesus, Palasi, Antoni, Penalba, Anna, Ramirez, Clara, Maisterra, Olga, Espinel, Eugenia, Ramos, Natalia, Pujadas, Francesc et al. DOI: 10.1016/j.jns.2019.116635
PMID: 32003834 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jan 1;35(Supplement_1):i13-i23. doi: 10.1093/ndt/gfz237. Impact factor: 4.531 Publication type: Paper in international publication Authors: Gorriz, Jose Luis, Vergara, Ander, Nunez, Julio, Jacobs-Cacha, Conxita, Martinez-Castelao, Alberto, Soler, Maria Jose, Ortiz, Alberto, Navarro-Gonzalez, Juan F et al. DOI: 10.1093/ndt/gfz237
A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.
An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.
Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.
