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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Team

Elena Isabel Crespo Gimeno

Elena Isabel Crespo Gimeno

Main researcher
Nephrology and kidney transplantation
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Irene Martinez Diaz

Irene Martinez Diaz

Predoctoral researcher
Nephrology and kidney transplantation
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Laura Donadeu Casassas

Laura Donadeu Casassas

Main researcher
Nephrology and kidney transplantation
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Mariona Juvé Torres

Mariona Juvé Torres

Research technician
Nephrology and kidney transplantation
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Elena Isabel Crespo Gimeno

Elena Isabel Crespo Gimeno

Main researcher
Nephrology and kidney transplantation
Read more
Irene Martinez Diaz

Irene Martinez Diaz

Predoctoral researcher
Nephrology and kidney transplantation
Read more
Laura Donadeu Casassas

Laura Donadeu Casassas

Main researcher
Nephrology and kidney transplantation
Read more
Mariona Juvé Torres

Mariona Juvé Torres

Research technician
Nephrology and kidney transplantation
Read more

Projects

Disección y promoción de inmunidad adaptativa específica frente al poliomavirus (BKV) para prevenir la infección viral tras el trasplante renal (proyecto BK-VAX).

IP: Oriol Bestard Matamoros
Collaborators: Disección y promoción de inmunidad adaptativa específica frente al poliomavirus (BKV) para prevenir la infección viral tras el t, Joana Sellarés Roig, Emma Pardo De los Santos, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, Narcís Saubí Roca
Funding agency: Instituto de Salud Carlos III
Funding: 174240
Reference: PI22/01019
Duration: 01/01/2023 - 31/12/2026

Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras MAP17 y D-AKAP-2 en ratones db/db y organoides renales humanos.

IP: Maria Jose Soler Romeo
Collaborators: Alejandra Gabaldon Dominguez, Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Irene Martinez Diaz, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras
Funding agency: Instituto de Salud Carlos III
Funding: 122210
Reference: PI21/01292
Duration: 01/01/2022 - 30/06/2026

HORUS: Casting light on HOst-cytomegaloviRUs interaction in Solid organ transplantation

IP: Oriol Bestard Matamoros
Collaborators: Elena Isabel Crespo Gimeno
Funding agency: EUROPEAN COMMISSION
Funding: 392651.25
Reference: HORUS_HE-HLTH-DISEASE_2021
Duration: 01/11/2022 - 31/10/2027

Blog

News

Antibody-mediated rejection remains one of the leading causes of graft loss following kidney transplantation. A VHIR study investigating a novel therapeutic strategy to address this challenge has been recognized with the Young Investigator Award 2026.

The distinction from the Catalan Transplant Society will allow her to become a member of the Royal Academy of Medicine of Catalonia.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.