About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Stroke is a medical emergency and one of the leading causes of death and disability worldwide. In this context, the Neurovascular Diseases Group was established in 2001, focusing on biomedical research into both ischemic and hemorrhagic stroke from a basic and translational perspective. Our work in this research field has covered the entire disease spectrum, from prevention and treatment to recovery. In 2017, we expanded our research interests to include vascular dementia and Alzheimer’s disease, related to the β-amyloid protein. Our ultimate goal as a research team is to help answer critical questions that will improve the clinical management of stroke and dementia, conditions with significant health impacts due to their high prevalence and associated disability. We are also committed to promoting scientific education among researchers and the society, and to fostering public engagement in these areas.
Since 2001, dozens of researchers have carried out their work in this laboratory, and as a team we have leaded translational and clinical projects through both preclinical studies with experimental models, as well as cohort studies in patients. The laboratory stands out for its extensive national and international collaborations, working closely with other research groups and the biomedical industry.
PMID: 33801197 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Mar 2;10(5). pii: jcm10050989. doi: 10.3390/jcm10050989. Impact factor: 4.242 Publication type: Paper in international publication Authors: Marazuela, Paula, Bonaterra-Pastra, Anna, Faura, Julia, Penalba, Anna, Pizarro, Jesus, Pancorbo, Olalla, Rodriguez-Luna, David, Vert, Carla, Rovira, Alex, Pujadas, Francesc et al. DOI: 10.3390/jcm10050989
PMID: 33805974 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2021 Reference: Int J Mol Sci. 2021 Mar 25;22(7). pii: ijms22073365. doi: 10.3390/ijms22073365. Impact factor: 5.924 Publication type: Review in international publication Authors: Unzeta, Mercedes, Hernandez-Guillamon, Mar, Sun, Ping, Sole, Montse et al. DOI: 10.3390/ijms22073365
PMID: 33738082 Journal: Journal of Extracellular Vesicles Year: 2021 Reference: J Extracell Vesicles. 2021 Mar;10(5):e12058. doi: 10.1002/jev2.12058. Epub 2021 Mar 12. Impact factor: 25.841 Publication type: Paper in international publication Authors: Seras-Franzoso, Joaquin, Diaz-Riascos, Zamira V, Corchero, Jose Luis, Gonzalez, Patricia, Garcia-Aranda, Natalia, Mandana, Monica, Riera, Roger, Boullosa, Ana, Mancilla, Sandra, Grayston, Alba et al. DOI: 10.1002/jev2.12058
PMID: 33710609 Journal: REVISTA DE NEUROLOGIA Year: 2021 Reference: Rev Neurol. 2021 Mar 16;72(6):195-202. doi: 10.33588/rn.7206.2020518. Impact factor: 0.87 Publication type: Paper in national publication Authors: Salas-Puig, J, Sopelana, D, Quintana, M, Seijo-Raposo, I, Abraira, L, Fonseca, E, Santamarina, E, Toledo, M et al. DOI: 10.33588/rn.7206.2020518
PMID: 32857458 Journal: EPILEPSIA Year: 2020 Reference: Epilepsia. 2020 Oct;61(10):2244-2253. doi: 10.1111/epi.16648. Epub 2020 Aug 28. Impact factor: 6.04 Publication type: Paper in international publication Authors: Terceno, Mikel, Zaragoza, Josep, Canovas, David, Gasull, Teresa, Ustrell, Xavier, Rubiera, Marta, Castellanos, Mar, Montaner, Joan, Alvarez-Sabin, Jose, Cardona, Pere et al. DOI: 10.1111/epi.16648
PMID: 32842922 Journal: STROKE Year: 2020 Reference: Stroke. 2020 Oct;51(10):3133-3137. doi: 10.1161/STROKEAHA.120.030326. Epub 2020 Aug 26. Impact factor: 7.19 Publication type: Paper in international publication Authors: Olive-Gadea, Marta, Crespo, Carlos, Granes, Cristina, Hernandez-Perez, Maria, Perez de la Ossa, Natalia, Laredo, Carlos, Urra, Xabier, Carlos Soler, Juan, Puyalto, Paloma, Cuadras, Patricia et al. DOI: 10.1161/STROKEAHA.120.030326
PMID: 32847948 Journal: NEUROLOGY Year: 2020 Reference: Neurology. 2020 Oct 27;95(17):e2331-e2342. doi: 10.1212/WNL.0000000000010614. Epub 2020 Aug 26. Impact factor: 8.77 Publication type: Paper in international publication Authors: Olive-Gadea, Marta, Meinel, Thomas Raphael, Kaesmacher, Johannes, Mosimann, Pascal John, Seiffge, David, Jung, Simon, Mordasini, Pasquale, Arnold, Marcel, Goeldlin, Martina, Hajdu, Steven D et al. DOI: 10.1212/WNL.0000000000010614
PMID: 32807790 Journal: Nature Communications Year: 2020 Reference: Nat Commun. 2020 Aug 17;11(1):4110. doi: 10.1038/s41467-020-17901-2. Impact factor: 12.121 Publication type: Paper in international publication Authors: Pitrez, Patricia R, Colell, Guillem, Vazao, Helena, Santinha, Deolinda, Harhouri, Karim, Thornton, Daniel, Navarro, Claire, Egesipe, Anne-Laure, Carvalho, Tania, Dos Santos, Rodrigo L et al. DOI: 10.1038/s41467-020-17901-2
PMID: 31077960 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2019 Reference: Seizure. 2019 Jul;69:193-197. doi: 10.1016/j.seizure.2019.04.022. Epub 2019 May 1. Impact factor: 2.765 Publication type: Paper in international publication Authors: Abraira, Laura, Toledo, Manuel, Guzman, Lorena, Sueiras, Maria, Quintana, Manuel, Fonseca, Elena, Salas-Puig, Javier, Alvarez-Sabin, Jose, Santamarina, Estevo et al. DOI: 10.1016/j.seizure.2019.04.022
PMID: 30918495 Journal: Frontiers in Neurology Year: 2019 Reference: Front Neurol. 2019 Mar 13;10:187. doi: 10.3389/fneur.2019.00187. eCollection 2019. Impact factor: 2.635 Publication type: Paper in international publication Authors: Camacho, Jessica, Moline, Teresa, Bonaterra-Pastra, Anna, Ramon Y Cajal, Santiago, Martinez-Saez, Elena, Hernandez-Guillamon, Mar et al. DOI: 10.3389/fneur.2019.00187
PMID: 30834194 Journal: Epilepsy & behavior case reports Year: 2019 Reference: Epilepsy Behav Case Rep. 2019 Feb 7;11:92-95. doi: 10.1016/j.ebcr.2019.01.008. eCollection 2019. Impact factor: 0 Publication type: Paper in international publication Authors: Santamarina, Estevo, Alpuente, Alicia, Maisterra, Olga, Sueiras, Maria, Sarria, Silvana, Guzman, Lorena, Abraira, Laura, Salas-Puig, Javier, Toledo, Manuel et al. DOI: 10.1016/j.ebcr.2019.01.008
PMID: 30803796 Journal: MEDICINA CLINICA Year: 2019 Reference: Med Clin (Barc). 2019 Jul 19;153(2):70-77. doi: 10.1016/j.medcli.2019.01.013. Epub 2019 Feb 23. Impact factor: 1.277 Publication type: Review in national publication Authors: Santamarina, Estevo, Abraira, Laura, Toledo, Manuel et al. DOI: 10.1016/j.medcli.2019.01.013
PMID: 29415332 Journal: JOURNAL OF INTERNAL MEDICINE Year: 2018 Reference: J Intern Med. 2018 May;283(5):461-475. doi: 10.1111/joim.12738. Epub 2018 Mar 5. Impact factor: 6.754 Publication type: Paper in international publication Authors: Simats, Alba, Garcia-Berrocoso, Teresa, Penalba, Anna, Giralt, Dolors, Llovera, Gemma, Jiang, Yinghua, Ramiro, Laura, Bustamante, Alejandro, Martinez-Saez, Elena, Canals, Francesc et al. DOI: 10.1111/joim.12738
PMID: 29326289 Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Year: 2018 Reference: J Neurol Neurosurg Psychiatry. 2018 Jun;89(6):651-656. doi: 10.1136/jnnp-2017-316724. Epub 2018 Jan 11. Impact factor: 7.144 Publication type: Paper in international publication Authors: Jimenez-Balado, Joan, Riba-Llena, Iolanda, Garde, Edurne, Valor, Marta, Gutierrez, Belen, Pujadas, Francesc, Delgado, Pilar et al. DOI: 10.1136/jnnp-2017-316724
PMID: 29133510 Journal: MOLECULAR & CELLULAR PROTEOMICS Year: 2018 Reference: Mol Cell Proteomics. 2018 Jan;17(1):175-189. doi: 10.1074/mcp.RA117.000419. Epub 2017 Nov 13. Impact factor: 5.232 Publication type: Paper in international publication Authors: Garcia-Berrocoso, Teresa, Llombart, Victor, Colas-Campas, Laura, Hainard, Alexandre, Licker, Virginie, Penalba, Anna, Ramiro, Laura, Simats, Alba, Martinez-Saez, Elena, Canals, Francesc et al. DOI: 10.1074/mcp.RA117.000419
PMID: 27956564 Journal: NEUROLOGY Year: 2016 Reference: Neurology. 2016 Dec 13;87(24):2533-2539. Epub 2016 Nov 9. Impact factor: 8.166 Publication type: Paper in international publication Authors: Vilar-Bergua, Andrea, Riba-Llena, Iolanda, Penalba, Anna, Jimenez-Balado, Joan, Montaner, Joan, Delgado, Pilar, Cruz, Luz Maria et al. DOI: 10.1212/WNL.0000000000003423
PMID: 27373742 Journal: ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION Year: 2016 Reference: Arch Phys Med Rehabil. 2016 Nov;97(11):1832-1840. doi: 10.1016/j.apmr.2016.06.007. Epub 2016 Jul 1. Impact factor: 3.045 Publication type: Paper in international publication Authors: Ma, Feifei, Rodriguez, Susana, Buxo, Xavi, Morancho, Anna, Riba-Llena, Iolanda, Carrera, Ana, Bustamante, Alejandro, Giralt, Dolors, Montaner, Joan, Martinez, Carmen et al. DOI: 10.1016/j.apmr.2016.06.007
PMID: 27168059 Journal: CLINICAL NEUROPSYCHOLOGIST Year: 2016 Reference: Clin Neuropsychol. 2016 Jan-Dec;30(sup1):1443-1456. Epub 2016 May 11. Impact factor: 1.556 Publication type: Paper in international publication Authors: Riba-Llena, Iolanda, Nafria, Cristina, Giralt, Dolors, Fernandez-Cortinas, Ines, Jarca, Carmen Ioana, Mundet, Xavier, Tovar, Jose Luis, Orfila, Francesc, Castane, Xavier, Alvarez-Sabin, Jose et al. DOI: 10.1080/13854046.2016.1174307
PMID: 26096669 Journal: NEUROLOGIA Year: 2016 Reference: Neurologia. 2016 May;31(4):231-238. doi: 10.1016/j.nrl.2015.05.002. Epub 2015 Jun 19. Impact factor: 1.79 Publication type: Paper in international publication Authors: Saez-Francas, N, Marti Andres, G, Ramirez, N, de Fabregues, O, Alvarez-Sabin, J, Hernandez-Vara, J, Casas, M et al. DOI: 10.1016/j.nrl.2015.05.002
For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.
The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.
The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.
