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Neurovascular Diseases

Stroke is a medical emergency and one of the leading causes of death and disability worldwide. In this context, the Neurovascular Diseases Group was established in 2001, focusing on biomedical research into both ischemic and hemorrhagic stroke from a basic and translational perspective. Our work in this research field has covered the entire disease spectrum, from prevention and treatment to recovery. In 2017, we expanded our research interests to include vascular dementia and Alzheimer’s disease, related to the β-amyloid protein. Our ultimate goal as a research team is to help answer critical questions that will improve the clinical management of stroke and dementia, conditions with significant health impacts due to their high prevalence and associated disability. We are also committed to promoting scientific education among researchers and the society, and to fostering public engagement in these areas.

Since 2001, dozens of researchers have carried out their work in this laboratory, and as a team we have leaded translational and clinical projects through both preclinical studies with experimental models, as well as cohort studies in patients. The laboratory stands out for its extensive national and international collaborations, working closely with other research groups and the biomedical industry.

Publications

Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management.

PMID: 33619704
Journal: DRUGS & AGING
Year: 2021
Reference: Drugs Aging. 2021 Apr;38(4):285-299. doi: 10.1007/s40266-021-00837-7. Epub 2021 Feb 23.
Impact factor: 3.923
Publication type: Review in international publication
Authors: Galovic, Marian, Ferreira-Atuesta, Carolina, Abraira, Laura, Dohler, Nico, Sinka, Lucia, Brigo, Francesco, Bentes, Carla, Zelano, Johan, Koepp, Matthias J et al.
DOI: 10.1007/s40266-021-00837-7

Incidence and mortality in adults with epilepsy in northern Spain.

PMID: 32969054
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2021
Reference: Acta Neurol Scand. 2021 Jan;143(1):27-33. doi: 10.1111/ane.13349. Epub 2020 Oct 13.
Impact factor: 3.209
Publication type: Paper in international publication
Authors: Quintana, Manuel, Sanchez-Lopez, Javier, Mazuela, Gonzalo, Santamarina, Estevo, Abraira, Laura, Fonseca, Elena, Seijo, Ivan, Alvarez-Sabin, Jose, Toledo, Manuel et al.
DOI: 10.1111/ane.13349

Corrigendum to 'Screening of Embolic Sources by Point-of-Care Ultrasound in the Acute Phase of Ischemic Stroke' [Ultrasound in Med. & Biol. 46 (2020) 2173-2180].

PMID: 33589352
Journal: ULTRASOUND IN MEDICINE AND BIOLOGY
Year: 2021
Reference: Ultrasound Med Biol. 2021 May;47(5):1428. doi: 10.1016/j.ultrasmedbio.2021.01.021. Epub 2021 Feb 12.
Impact factor: 2.998
Publication type: Letter or abstract
Authors: Juega, Jesus, Pagola, Jorge, Gonzalez-Alujas, Teresa, Rodriguez-Luna, David, Rubiera, Marta, Rodriguez-Villatoro, Noelia, Garcia-Tornel, Alvaro, Requena, Manuel, Deck, Matias, Sero, Laia et al.
DOI: 10.1016/j.ultrasmedbio.2021.01.021

Blood Biomarkers to Predict Long-Term Mortality after Ischemic Stroke.

PMID: 33578805
Journal: Life-Basel
Year: 2021
Reference: Life (Basel). 2021 Feb 10;11(2). pii: life11020135. doi: 10.3390/life11020135.
Impact factor: 3.817
Publication type: Paper in international publication
Authors: Ramiro, Laura, Abraira, Laura, Quintana, Manuel, Garcia-Rodriguez, Paula, Santamarina, Estevo, Alvarez-Sabin, Jose, Zaragoza, Josep, Hernandez-Perez, Maria, Ustrell, Xavier, Lara, Blanca et al.
DOI: 10.3390/life11020135

Circulating TIMP-1 is associated with hematoma volume in patients with spontaneous intracranial hemorrhage.

PMID: 32587306
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Jun 25;10(1):10329. doi: 10.1038/s41598-020-67250-9.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Navarro-Oviedo, Manuel, Munoz-Arrondo, Roberto, Zandio, Beatriz, Marta-Enguita, Juan, Bonaterra-Pastra, Anna, Rodriguez, Jose Antonio, Roncal, Carmen, Paramo, Jose A, Toledo, Estefania, Montaner, Joan et al.
DOI: 10.1038/s41598-020-67250-9

Screening of Embolic Sources by Point-of-Care Ultrasound in the Acute Phase of Ischemic Stroke.

PMID: 32532655
Journal: ULTRASOUND IN MEDICINE AND BIOLOGY
Year: 2020
Reference: Ultrasound Med Biol. 2020 Sep;46(9):2173-2180. doi: 10.1016/j.ultrasmedbio.2020.05.009. Epub 2020 Jun 10.
Impact factor: 2.514
Publication type: Paper in international publication
Authors: Juega, Jesus, Pagola, Jorge, Gonzalez-Alujas, Teresa, Rodriguez-Luna, David, Rubiera, Marta, Rodriguez-Villatoro, Noelia, Garcia-Tornel, Alvaro, Requena, Manuel, Deck, Matias, Sero, Laia et al.
DOI: 10.1016/j.ultrasmedbio.2020.05.009

Ambulatory Blood Pressure Levels in the Prediction of Progression of Cerebral Small Vessel Disease.

PMID: 32511756
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2020
Reference: J Am Geriatr Soc. 2020 Oct;68(10):2232-2239. doi: 10.1111/jgs.16568. Epub 2020 Jun 8.
Impact factor: 4.18
Publication type: Paper in international publication
Authors: Palasi, Antoni, Pujadas, Francesc, Mundet, Xavier, Vinyoles, Ernest, Delgado, Pilar, Pizarro, Jesus, Maisterra, Olga, Riba-Llena, Iolanda, Jimenez-Balado, Joan et al.
DOI: 10.1111/jgs.16568

Cardioembolic Ischemic Stroke Gene Expression Fingerprint in Blood: a Systematic Review and Verification Analysis.

PMID: 31475302
Journal: Translational Stroke Research
Year: 2020
Reference: Transl Stroke Res. 2020 Jun;11(3):326-336. doi: 10.1007/s12975-019-00730-x. Epub 2019 Sep 2.
Impact factor: 5.78
Publication type: Review in international publication
Authors: Clua-Espuny, Josep Lluis, Pedrote, Alonso, Pagola, Jorge, Juega, Jesus, Bustamante, Alejandro, Montaner, Joan, Munoz, Miguel Angel, Jickling, Glen C, Meisel, Christian, Meisel, Andreas et al.
DOI: 10.1007/s12975-019-00730-x

Cognitive Impact of Cerebral Small Vessel Disease Changes in Patients With Hypertension.

PMID: 30606062
Journal: HYPERTENSION
Year: 2019
Reference: Hypertension. 2019 Feb;73(2):342-349. doi: 10.1161/HYPERTENSIONAHA.118.12090.
Impact factor: 7.017
Publication type: Paper in international publication
Authors: Delgado, Pilar, Ventura, Oriol, Jimenez-Balado, Joan, Riba-Llena, Iolanda, Abril, Oscar, Garde, Edurne, Penalba, Anna, Ostos, Elena, Maisterra, Olga, Montaner, Joan et al.
DOI: 10.1161/HYPERTENSIONAHA.118.12090

Blog

News

For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.

The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.