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Neurovascular Diseases

Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.

Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.

Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.

Publications

Comparison of Plasma Lipoprotein Composition and Function in Cerebral Amyloid Angiopathy and Alzheimer's Disease.

PMID: 33445800
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Jan 12;9(1). pii: biomedicines9010072. doi: 10.3390/biomedicines9010072.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Vera, Rocio, Lebrato-Hernandez, Lucia, Arenillas, Juan F, Perez-Sanchez, Soledad, Montaner, Joan, Sanchez-Quesada, Jose Luis, Hernandez-Guillamon, Mar, Cardona Portela, Pere, Martinez-Zabaleta, Maite, Tur, Silvia et al.
DOI: 10.3390/biomedicines9010072

Role of Blood-Based Biomarkers in Ischemic Stroke Prognosis: A Systematic Review.

PMID: 33430636
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 Jan;52(2):543-551. doi: 10.1161/STROKEAHA.120.029232. Epub 2021 Jan 12.
Impact factor: 7.914
Publication type: Review in international publication
Authors: Montellano, Felipe A, Ungethum, Kathrin, Ramiro, Laura, Nacu, Aliona, Hellwig, Simon, Fluri, Felix, Whiteley, William N, Bustamante, Alejandro, Montaner, Joan, Heuschmann, Peter U et al.
DOI: 10.1161/STROKEAHA.120.029232

Defining a Target Population to Effectively Test a Neuroprotective Drug.

PMID: 33423513
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 Jan;52(2):505-510. doi: 10.1161/STROKEAHA.120.032025. Epub 2021 Jan 11.
Impact factor: 7.914
Publication type: Paper in international publication
Authors: Garcia-Tornel, Alvaro, Deck, Matias, Muchada, Marian, Boned, Sandra, Rodriguez, Noelia, Juega, Jesus, Rodriguez-Luna, David, Pagola, Jorge, Rubiera, Marta, Hernandez-Jimenez, Macarena et al.
DOI: 10.1161/STROKEAHA.120.032025

Nighttime hypoxia affects global cognition, memory, and executive function in community-dwelling individuals with hypertension.

PMID: 31992414
Journal: Journal of Clinical Sleep Medicine
Year: 2020
Reference: J Clin Sleep Med. 2020 Feb 15;16(2):243-250. doi: 10.5664/jcsm.8174. Epub 2020 Jan 13.
Impact factor: 3.586
Publication type: Paper in international publication
Authors: Riba-Llena, Iolanda, Alvarez-Sabin, Jose, Romero, Odile, Santamarina, Estevo, Sampol, Gabriel, Maisterra, Olga, Ferre, Alex, Montaner, Joan, Quintana, Manuel, Delgado, Pilar et al.
DOI: 10.5664/jcsm.8174

Endovascular Stroke Treatment and Risk of Intracranial Hemorrhage in Anticoagulated Patients.

PMID: 31992179
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Mar;51(3):892-898. doi: 10.1161/STROKEAHA.119.026606. Epub 2020 Jan 29.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Seiffge, David J, Meinel, Thomas R, Kniepert, Joachim U, Fischer, Urs, Auer, Elias, Frey, Sebastien, Goeldlin, Martina, Mordasini, Pasquale, Mosimann, Pascal J, Nogueira, Raul G et al.
DOI: 10.1161/STROKEAHA.119.026606

Circulating Aquaporin-4 as a biomarker of early neurological improvement in stroke patients: a pilot study.

PMID: 31672489
Journal: NEUROSCIENCE LETTERS
Year: 2020
Reference: Neurosci Lett. 2020 Jan 1;714:134580. doi: 10.1016/j.neulet.2019.134580. Epub 2019 Oct 28.
Impact factor: 2.274
Publication type: Paper in international publication
Authors: Ramiro, Laura, Simats, Alba, Penalba, Anna, Garcia-Tornel, Alvaro, Rovira, Alex, Mancha, Fernando, Bustamante, Alejandro, Montaner, Joan et al.
DOI: 10.1016/j.neulet.2019.134580

Blog

News

For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.

The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.