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Ophtalmology

The clinical and basic research activity of the Ophthalmology Research Group is dedicated to finding new treatments for blindness through the development of new therapies for macular and retinal degenerative diseases, as well as for retinal vascular diseases (diabetic retinopathy and retinal vascular occlusions). Our group consists of core researchers and clinical researchers, so there is a clear clinical translation of the ongoing research in the research group.

We have a research program for the development of new therapeutic strategies based on:

  • Cell therapies
  • Formulations of ocular solutions (LUCIA PI18 and CELLUX EuroNanoMed/AC19)
  • Biological matrices
  • Gene therapy
  • Animal models
  • Retinal cell models based on stem cell-derived organoids.

In the clinical part, the research group bases its activity on clinical trials to develop new treatments for retinal diseases as well as on the ophthalmic involvement of systemic treatments, an example is the phase II trial to test mesenchymal cells (MSV) intravitreal in non-arteritic ischemic optic neuropathy (NAION), the RECOGNISED study or the PULSAR study with aflibercept.

Team

Alfredo Pueyo Ferrer

Alfredo Pueyo Ferrer

Research technician
Ophtalmology
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Eric Kirkegaard Biosca

Eric Kirkegaard Biosca

Research technician
Ophtalmology
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Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
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Sara Martin Nalda

Sara Martin Nalda

Ophtalmology
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Laia Bisbe López

Laia Bisbe López

Ophtalmology
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Silvia Alarcón Portabella

Silvia Alarcón Portabella

Research assistant
Ophtalmology
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Alfredo Pueyo Ferrer

Alfredo Pueyo Ferrer

Research technician
Ophtalmology
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Eric Kirkegaard Biosca

Eric Kirkegaard Biosca

Research technician
Ophtalmology
Read more
Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
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Sara Martin Nalda

Sara Martin Nalda

Ophtalmology
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Laia Bisbe López

Laia Bisbe López

Ophtalmology
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Silvia Alarcón Portabella

Silvia Alarcón Portabella

Research assistant
Ophtalmology
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Research lines

Non-viral gene therapy with Pigment Epithelium-Derived Factor (PEDF) in the treatment of dry and wet forms of AMD

IP: -

Projects

RETVISION: Del diagnóstico genético molecular a las terapias avanzadas para tratar las enfermedades degenerativas de la retina.

IP: José García Arumí
Collaborators: María Antolín Mate, Anna Duarri Piqué, Claudia Garcia-Arumí Fusté, Miguel Angel Zapata Victori, Laura Natalia Distefano, Maddalen Zufiaurre Seijo
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI22/01747
Duration: 01/01/2023 - 31/12/2025

Enfermedades Inflamatorias

IP: José García Arumí
Collaborators: Anna Duarri Piqué, Ana Boixadera Espax, Miguel Angel Zapata Victori, Laura Natalia Distefano
Funding agency: Instituto de Salud Carlos III
Funding: 148776.1
Reference: RD21/0002/0052
Duration: 01/01/2022 - 31/12/2024

Phase III clinical trial of intravitreal MSV (PEI 15-007) in non-arteritic ischemic optic neuropathy (NAION)

IP: José García Arumí
Collaborators: Miguel Angel Zapata Victori
Funding agency: Instituto de Salud Carlos III
Funding: 345950
Reference: PIC18/00018
Duration: 01/01/2019 - 31/12/2024

LUCIA: Determinación de las condiciones para el uso de nanoparticulas de óxido de cerlo Antioxidantes en el tratamiento de la degeneración retiniana humana.

IP: José García Arumí
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI18/00219
Duration: 01/01/2019 - 30/06/2023

Blog

News

On January 24, a session was held to explain what these three-dimensional models are and what advantages they have, as well as to review some of their applications in research.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Dr. José García Arumi and Dr. Anna Duarri from the Ophthalmology research group at Vall Hebron Recerca lead the project.