Skip to main content

Ophtalmology

The clinical and basic research activity of the Ophthalmology Research Group is dedicated to finding new treatments for blindness through the development of new therapies for macular and retinal degenerative diseases, as well as for retinal vascular diseases (diabetic retinopathy and retinal vascular occlusions). Our group consists of core researchers and clinical researchers, so there is a clear clinical translation of the ongoing research in the research group.

We have a research program for the development of new therapeutic strategies based on:

  • Cell therapies
  • Formulations of ocular solutions (LUCIA PI18 and CELLUX EuroNanoMed/AC19)
  • Biological matrices
  • Gene therapy
  • Animal models
  • Retinal cell models based on stem cell-derived organoids.

In the clinical part, the research group bases its activity on clinical trials to develop new treatments for retinal diseases as well as on the ophthalmic involvement of systemic treatments, an example is the phase II trial to test mesenchymal cells (MSV) intravitreal in non-arteritic ischemic optic neuropathy (NAION), the RECOGNISED study or the PULSAR study with aflibercept.

Publications

Efficacy of Internal Limiting Membrane Flap Techniques with Vitrectomy for Macular Detachment Associated with an Optic Disc Pit.

PMID: 30808833
Journal: OPHTHALMOLOGICA
Year: 2019
Reference: Ophthalmologica. 2019;242(1):38-48. doi: 10.1159/000495621. Epub 2019 Mar 22.
Impact factor: 1.781
Publication type: Paper in international publication
Authors: Pastor-Idoate, Salvador, Gomez-Resa, Maria, Karam, Sarah, Copete, Sergio, Kyriakou, Danai, Garcia-Arumi Fuste, Claudia, Pastora, Natalia, Nadal, Jeroni, Garcia-Arumi, Jose et al.
DOI: 10.1159/000495621

The EX-PRESS glaucoma shunt versus nonpenetrating deep sclerectomy with Esnoper implant in combined surgery for open-angle glaucoma: a prospective randomized study.

PMID: 30714336
Journal: ACTA OPHTHALMOLOGICA
Year: 2019
Reference: Acta Ophthalmol. 2019 Nov;97(7):e952-e961. doi: 10.1111/aos.14023. Epub 2019 Feb 3.
Impact factor: 3.153
Publication type: Paper in international publication
Authors: Munoz, Marcos, Anton, Alfonso, Castany, Marta, Gil, Alfonso, Martinez, Alberto, Munoz-Negrete, Francisco J, Urcelay, Jose, Moreno-Montanes, Javier et al.
DOI: 10.1111/aos.14023

Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy. Results of the EUROCONDOR Clinical Trial.

PMID: 30389750
Journal: DIABETES
Year: 2019
Reference: Diabetes. 2019 Feb;68(2):457-463. doi: 10.2337/db18-0682. Epub 2018 Nov 2.
Impact factor: 7.199
Publication type: Paper in international publication
Authors: Simo, Rafael, Hernandez, Cristina, Porta, Massimo, Bandello, Francesco, Grauslund, Jakob, Harding, Simon P, Aldington, Stephen J, Egan, Catherine, Frydkjaer-Olsen, Ulrik, Garcia-Arumi, Jose et al.
DOI: 10.2337/db18-0682

Long-term probability of intraocular pressure elevation with the intravitreal dexamethasone implant in the real-world.

PMID: 30608950
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Jan 4;14(1):e0209997. doi: 10.1371/journal.pone.0209997. eCollection 2019.
Impact factor: 2.776
Publication type: Paper in international publication
Authors: Zarranz-Ventura, Javier, Sala-Puigdollers, Anna, Velazquez-Villoria, Daniel, Figueras-Roca, Marc, Copete, Sergio, Distefano, Laura, Boixadera, Anna, Garcia-Arumi, Jose, Adan, Alfredo et al.
DOI: 10.1371/journal.pone.0209997

Blog

News

On January 24, a session was held to explain what these three-dimensional models are and what advantages they have, as well as to review some of their applications in research.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Dr. José García Arumi and Dr. Anna Duarri from the Ophthalmology research group at Vall Hebron Recerca lead the project.