Peripheral Nervous System
Our laboratory, in the Neuromuscular Disorders Unit of the Neurology Service, has a twenty-year history of clinical care and research into amyotrophic lateral sclerosis (ALS) and other motor neurone diseases (hereditary, spastic paraplegia, post-polio syndrome, Hirayama disease, spinal muscular atrophy), myasthenia gravis, genetically determined myopathies, and peripheral neuropathies. Our main lines of research focus on the molecular mechanisms of amyotrophic lateral sclerosis and how genetic mutations in family ELA predispose or modify genetic factors. We also look for effective biomarkers in blood and in cerebrospinal fluid that allow the evaluation of new medication.
Publications
Anatomical study of first palmar intermetacarpal flap in cadavers and application for congenital first web contracture in a child with Apert's syndrome.
PMID: 37953638
Journal: MICROSURGERY
Year: 2023
Reference: Microsurgery. 2023 Nov 12. doi: 10.1002/micr.31134.
Impact factor:
Publication type: Paper in international publication
Authors: Attarian, Shahram; Beloribi-Djefaflia, Sadia; Bonello-Palot, Nathalie; de Oliveira, Ricardo Kaempf; Fatehi, Farzad; Gidaro, Teresa; Isapof, Arnaud; Leonard-Louis, Sarah; Michaud, Maud; Morales, Raul Juntas et al.
DOI: 10.1002/micr.31134
Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases.
PMID: 31645906
Journal: Oncotarget
Year: 2019
Reference: Oncotarget. 2019 Oct 8;10(56):5871-5887. doi: 10.18632/oncotarget.27232. eCollection 2019 Oct 8.
Impact factor: 0
Publication type: Paper in international publication
Authors: Alvarez-Palomo, Belen, Barrot-Feixat, Carme, Sarret, Helena, Requena, Jordi, Pau, Montserrat, Vidal-Taboada, Jose-Manuel, Oliva, Rafael, Ballesca, Josep-Lluis, Edel, Michael J, Mezquita-Pla, Jovita et al.
DOI: 10.18632/oncotarget.27232