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Pharmacokinetic Nanoparticles

The group of design and pharmacodynamics of nanoparticles at the Vall d’Hebron Research Institute focuses on the synthesis, characterization, and applications of engineered inorganic nanoparticles in the field of medicine. By mastering the inorganic core (size, structure, and shape) and understanding and controlling the linking of molecules to the nanoparticle surface, we engineer nanoparticles that can interact with biological systems in a specific way. We also put particular emphasis on safety, feasibility, scale-up, applicability, and other aspects of nanoparticle design.

Our group is led by Prof. Víctor Puntes, who holds an ICREA Research Professorship. Since a great part of our work demands highly multidisciplinary expertise, we maintain several strong collaborations with biologists, immunologists, oncologists, physicists, environmentalists, and more, from all over Europe, China and the US. The work of the group has resulted in several patents and the creation of several spin-offs such as Nanotargeting and Applied nanoparticles.

Publications

In Vitro Antibacterial Activity of Silver Nanoparticles Conjugated with Amikacin and Combined with Hyperthermia against Drug-Resistant and Biofilm-Producing Strains.

PMID: 37078875
Journal: Microbiology Spectrum
Year: 2023
Reference: Microbiol Spectr. 2023 Apr 20:e0028023. doi: 10.1128/spectrum.00280-23.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Gavalda, Joan; Gilabert, Joan; Gomis, Xavier; Gusta, Muriel F; Larrosa, Nieves; Munoz, Estela; Palau, Marta; Puntes, Victor; Texido, Robert et al.
DOI: 10.1128/spectrum.00280-23