About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of design and pharmacodynamics of nanoparticles at the Vall d’Hebron Research Institute focuses on the synthesis, characterization, and applications of engineered inorganic nanoparticles in the field of medicine. By mastering the inorganic core (size, structure, and shape) and understanding and controlling the linking of molecules to the nanoparticle surface, we engineer nanoparticles that can interact with biological systems in a specific way. We also put particular emphasis on safety, feasibility, scale-up, applicability, and other aspects of nanoparticle design.
Our group is led by Prof. Víctor Puntes, who holds an ICREA Research Professorship. Since a great part of our work demands highly multidisciplinary expertise, we maintain several strong collaborations with biologists, immunologists, oncologists, physicists, environmentalists, and more, from all over Europe, China and the US. The work of the group has resulted in several patents and the creation of several spin-offs such as Nanotargeting and Applied nanoparticles.
PMID: 37764620 Journal: Nanomaterials Year: 2023 Reference: Nanomaterials (Basel). 2023 Sep 19;13(18):2590. doi: 10.3390/nano13182590. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Patarroyo, Javier; Puntes, Victor; Puntes, Victor et al. DOI: 10.3390/nano13182590
PMID: 37789037 Journal: Nature Communications Year: 2023 Reference: Nat Commun. 2023 Oct 3;14(1):6165. doi: 10.1038/s41467-023-41976-2. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Cazorla, Claudio; Chen, Yufen; Llorca, Jordi; Oliveras, Jana; Puntes, Victor F; Puntes, Victor F; Soler, Lluis; Soler, Lluis et al. DOI: 10.1038/s41467-023-41976-2
PMID: 37078875 Journal: Microbiology Spectrum Year: 2023 Reference: Microbiol Spectr. 2023 Apr 20:e0028023. doi: 10.1128/spectrum.00280-23. Impact factor: Publication type: Paper in international publication Authors: Almirante, Benito; Gavalda, Joan; Gilabert, Joan; Gomis, Xavier; Gusta, Muriel F; Larrosa, Nieves; Munoz, Estela; Palau, Marta; Puntes, Victor; Texido, Robert et al. DOI: 10.1128/spectrum.00280-23
PMID: 35401546 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Mar 17;13:750175. doi: 10.3389/fimmu.2022.750175. eCollection 2022. Impact factor: Publication type: Paper in international publication Authors: Ernst, Lena M; Puntes, Victor et al. DOI: 10.3389/fimmu.2022.750175
PMID: 35159859 Journal: Nanomaterials Year: 2022 Reference: Nanomaterials (Basel). 2022 Feb 1;12(3). pii: nano12030511. doi: 10.3390/nano12030511. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Dubaj, Tibor; Dusinska, Maria; Gabelova, Alena; Kohl, Yvonne; Kozics, Katarina; Manova, Alena; Moriones, Oscar H; Nelson, Andrew; Puntes, Victor et al. DOI: 10.3390/nano12030511
PMID: 35159859 Journal: Nanomaterials Year: 2022 Reference: Nanomaterials (Basel). 2022 Feb 1;12(3). pii: nano12030511. doi: 10.3390/nano12030511. Impact factor: 5.076 Publication type: Paper in international publication Authors: Manova, Alena; Bastus, Neus G; Moriones, Oscar H; Kohl, Yvonne; Dusinska, Maria; Runden-Pran, Elise; Puntes, Victor; Nelson, Andrew; Gabelova, Alena; Simon, Peter et al. DOI: 10.3390/nano12030511
PMID: 35401546 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Mar 17;13:750175. doi: 10.3389/fimmu.2022.750175. eCollection 2022. Impact factor: 7.561 Publication type: Paper in international publication Authors: Ernst, Lena M, Puntes, Victor et al. DOI: 10.3389/fimmu.2022.750175
PMID: 33973797 Journal: Nanomedicine Year: 2021 Reference: Nanomedicine (Lond). 2021 Jun;16(13):1133-1151. doi: 10.2217/nnm-2021-0030. Epub 2021 May 11. Impact factor: Publication type: Review in international publication Authors: Aliabadi, Alireza; Ansari, Ali; Casals, Eudald; Derakhshankhah, Hossein; Ghorbani, Milad; Izadi, Zhila; Jafari, Samira; Jaymand, Mehdi; Moore, Alycia; Puntes, Victor et al. DOI: 10.2217/nnm-2021-0030
PMID: 33923136 Journal: Antioxidants Year: 2021 Reference: Antioxidants (Basel). 2021 Apr 24;10(5). pii: antiox10050660. doi: 10.3390/antiox10050660. Impact factor: Publication type: Review in international publication Authors: Casals, Eudald; Casals, Gregori; Fernandez-Varo, Guillermo; Jimenez, Wladimiro; Morales-Ruiz, Manuel; Perramon, Meritxell; Portoles, Irene; Puntes, Victor et al. DOI: 10.3390/antiox10050660
PMID: 33784953 Journal: Nanotoxicology Year: 2021 Reference: Nanotoxicology. 2021 May;15(4):558-576. doi: 10.1080/17435390.2021.1898690. Epub 2021 Mar 30. Impact factor: Publication type: Review in international publication Authors: Boraschi, Diana; De Luca, Anna Chiara; Italiani, Paola; Mangini, Maria; Puntes, Victor F; Verde, Alessandro et al. DOI: 10.1080/17435390.2021.1898690
PMID: 33736322 Journal: SCIENCE OF THE TOTAL ENVIRONMENT Year: 2021 Reference: Sci Total Environ. 2021 May 10;768:144792. doi: 10.1016/j.scitotenv.2020.144792. Epub 2021 Jan 27. Impact factor: Publication type: Paper in international publication Authors: Barbero, Francesco; Bastus, Neus G; Drobne, Damjana; Mayall, Craig; Puntes, Victor; Saiz-Poseu, Javier et al. DOI: 10.1016/j.scitotenv.2020.144792
PMID: 32329572 Journal: Small Year: 2020 Reference: Small. 2020 May;16(20):e1907322. doi: 10.1002/smll.201907322. Epub 2020 Apr 24. Impact factor: Publication type: Review in international publication Authors: Casals, Eudald; Casals, Gregori; Fernandez-Varo, Guillermo; Jimenez, Wladimiro; Morales-Ruiz, Manuel; Parra-Robert, Marina; Puntes, Victor; Zeng, Muling et al. DOI: 10.1002/smll.201907322
PMID: 32197356 Journal: Nanomaterials Year: 2020 Reference: Nanomaterials (Basel). 2020 Mar 18;10(3). pii: nano10030545. doi: 10.3390/nano10030545. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Dusinska, Maria; Elje, Elisabeth; Kohl, Yvonne; Mariussen, Espen; Moriones, Oscar H; Puntes, Victor; Runden-Pran, Elise et al. DOI: 10.3390/nano10030545
PMID: 31961955 Journal: HEPATOLOGY Year: 2020 Reference: Hepatology. 2020 Oct;72(4):1267-1282. doi: 10.1002/hep.31139. Impact factor: Publication type: Paper in international publication Authors: Boix, Loreto; Bruix, Jordi; Carvajal, Silvia; Casado, Pedro; Casals, Eudald; Casals, Gregori; Cutillas, Pedro R; Fernandez-Varo, Guillermo; Fuster, Josep; Garcia-Valdecasas, Juan Carlos et al. DOI: 10.1002/hep.31139
PMID: 32692793 Journal: Nanoscale Year: 2020 Reference: Nanoscale. 2020 Aug 7;12(29):15832-15844. doi: 10.1039/d0nr02379e. Epub 2020 Jul 21. Impact factor: 6.895 Publication type: Paper in international publication Authors: Vitali, Michele, Casals, Eudald, Canals, Francesc, Colome, Nuria, Puntes, Victor et al. DOI: 10.1039/d0nr02379e
PMID: 31470518 Journal: Biomolecules Year: 2019 Reference: Biomolecules. 2019 Aug 29;9(9). pii: biom9090425. doi: 10.3390/biom9090425. Impact factor: Publication type: Paper in international publication Authors: Casals, Eudald; Casals, Gregori; Fernandez-Varo, Guillermo; Jimenez, Wladimiro; Massana, Nuria; Morales-Ruiz, Manuel; Parra-Robert, Marina; Perramon, Meritxell; Puntes, Victor; Zeng, Muling et al. DOI: 10.3390/biom9090425
PMID: 31135010 Journal: Nanoscale Year: 2019 Reference: Nanoscale. 2019 Jun 6;11(22):10819-10827. doi: 10.1039/c9nr02397f. Impact factor: Publication type: Paper in international publication Authors: Hamad-Schifferli, Kimberly; Leonardo, Brianna M; Puntes, Victor; Rodriguez-Quijada, Cristina; Russo, Lorenzo; Sanchez-Purra, Maria et al. DOI: 10.1039/c9nr02397f
PMID: 31026038 Journal: ALTEX-Alternatives to Animal Experimentation Year: 2019 Reference: ALTEX. 2019;36(4):583-596. doi: 10.14573/altex.1902061. Epub 2019 Apr 26. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Fischer, Benjamin; Gentile, Luca; Hesler, Michelle; Jimeno-Romero, Alba; Kohl, Yvonne L; Moriones, Oscar H; Puntes, Victor; Tran, Thao A; Wagner, Sylvia et al. DOI: 10.14573/altex.1902061
PMID: 28376428 Journal: SCIENCE OF THE TOTAL ENVIRONMENT Year: 2017 Reference: Sci Total Environ. 2017 Oct 1;595:51-62. doi: 10.1016/j.scitotenv.2017.03.229. Epub 2017 Apr 1. Impact factor: Publication type: Review in international publication Authors: Abo Markeb, Ahmad; Alonso, Amanda; Busquets-Fite, Marti; Font, Xavier; Komilis, Dimitrios; Moral-Vico, J; Puntes, Victor; Sanchez, Antoni et al. DOI: 10.1016/j.scitotenv.2017.03.229
PMID: 28508592 Journal: CHEMISTRY-A EUROPEAN JOURNAL Year: 2017 Reference: Chemistry. 2017 Jun 27;23(36):8623-8627. doi: 10.1002/chem.201702072. Epub 2017 Jun 13. Impact factor: Publication type: Paper in international publication Authors: Guillerm, Vincent; Maspoch, Daniel; Perez-Carvajal, Javier; Puntes, Victor; Rodriguez-San-Miguel, David; Yazdi, Amirali; Zamora, Felix et al. DOI: 10.1002/chem.201702072
PMID: 29285024 Journal: Frontiers in Immunology Year: 2017 Reference: Front Immunol. 2017 Dec 22;8:1891. doi: 10.3389/fimmu.2017.01891. eCollection 2017. Impact factor: Publication type: Letter or abstract Authors: Casals, Eudald; Casals, Gregori; Gusta, Muriel F; Jimenez, Wladimiro; Piella, Jordi; Puntes, Victor et al. DOI: 10.3389/fimmu.2017.01891
PMID: 29192556 Journal: Nanotoxicology Year: 2017 Reference: Nanotoxicology. 2017 Nov - Dec;11(9-10):1157-1175. doi: 10.1080/17435390.2017.1401142. Epub 2017 Dec 1. Impact factor: Publication type: Paper in international publication Authors: Andosch, Ancuela; Boraschi, Diana; Casals, Eudald; Cobaleda, Macarena; Duschl, Albert; Himly, Martin; Horejs-Hoeck, Jutta; Italiani, Paola; Jaberi-Douraki, Majid; Li, Yang et al. DOI: 10.1080/17435390.2017.1401142
PMID: 27524251 Journal: ENVIRONMENTAL POLLUTION Year: 2016 Reference: Environ Pollut. 2016 Nov;218:870-878. doi: 10.1016/j.envpol.2016.08.016. Epub 2016 Aug 11. Impact factor: Publication type: Paper in international publication Authors: Dimmers, Wim J; Makama, Sunday; Peters, Ruud; Piella, Jordi; Puntes, Victor F; Undas, Anna; van den Brink, Nico W et al. DOI: 10.1016/j.envpol.2016.08.016
PMID: 27498830 Journal: CHEMICAL COMMUNICATIONS Year: 2016 Reference: Chem Commun (Camb). 2016 Sep 21;52(73):10960-3. doi: 10.1039/c6cc04796c. Epub 2016 Aug 8. Impact factor: Publication type: Paper in international publication Authors: Arbiol, Jordi; Bastus, Neus G; Genc, Aziz; Patarroyo, Javier; Puntes, Victor et al. DOI: 10.1039/c6cc04796c
PMID: NO PMID1 Journal: ENVIRONMENTAL SCIENCE & TECHNOLOGY Year: 2016 Reference: Environ. Sci. Technol., 2016, 50 (5), pp 2584–2594 Impact factor: Publication type: Paper in international publication Authors: David González Gálvez; Elisabet Fernandez-Rosas; Gemma Janer; Gemma Vilar; Laurent Aubouy; Socorro Vázquez-Campos; Victor Franco Puntes; Vincent Jamier et al. DOI: 10.1021/acs.est.5b05727
PMID: NO PMID2 Journal: CHEMISTRY OF MATERIALS Year: 2016 Reference: Chem. Mater., 2016, 28 (4), pp 1066–1075 Impact factor: Publication type: Paper in international publication Authors: Jordi Piella; Neus G Bastús; Victor Puntes et al. DOI: 10.1021/acs.chemmater.5b04406
