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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Francesc Xavier Molero Richard

Francesc Xavier Molero Richard

Physiology and Pathophysiology of the Digestive Tract
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Luis Gerardo Alcala Gonzalez

Luis Gerardo Alcala Gonzalez

Main researcher
Physiology and Pathophysiology of the Digestive Tract
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Nadia Vázquez Platel

Nadia Vázquez Platel

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Oscar José Hernández Cristancho

Oscar José Hernández Cristancho

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Polo Figueres, Laura

Polo Figueres, Laura

Physiology and Pathophysiology of the Digestive Tract
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Raul Velamazan Sandalinas

Raul Velamazan Sandalinas

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Francesc Xavier Molero Richard

Francesc Xavier Molero Richard

Physiology and Pathophysiology of the Digestive Tract
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Luis Gerardo Alcala Gonzalez

Luis Gerardo Alcala Gonzalez

Main researcher
Physiology and Pathophysiology of the Digestive Tract
Read more
Nadia Vázquez Platel

Nadia Vázquez Platel

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Oscar José Hernández Cristancho

Oscar José Hernández Cristancho

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Polo Figueres, Laura

Polo Figueres, Laura

Physiology and Pathophysiology of the Digestive Tract
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Raul Velamazan Sandalinas

Raul Velamazan Sandalinas

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Projects

Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR.

IP: -
Collaborators: Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y, Eva Polverino
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI22/00887
Duration: 01/01/2023 - 31/12/2025

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (DISCOvERIE)

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez, Silvia Muñoz Caller, Carmen Alonso Cotoner, Natalia Rodriguez Santas, Ana Maria Gonzalez Castro, Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (D, Marc Pigrau Pastor, Adoración Nieto Ruiz, Alejandro Henao Paez, Consuelo Cammarota , José Alegre Martin, Jesus Castro Marrero, Marta Ribases Haro, Natalia Llonga Tejedor, Amanda Rodríguez Urrutia
Funding agency: EUROPEAN COMMISSION
Funding: 1148684.84
Reference: DISCOVERIE_H2020-SC1-BHC2019
Duration: 01/01/2020 - 31/05/2025

Contribución diferencial del epitelio intestinal a la fisiopatología de la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica. Perfil clínico-biológico para el diagnóstico diferencial.

IP: -
Collaborators: Beatriz Lobo Alvarez, Merce Albert Bayo, Inés de Torres Ramirez, Natalia Rodriguez Santas, Ana Maria Gonzalez Castro, Marc Pigrau Pastor
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI19/01643
Duration: 01/01/2020 - 30/06/2024

Inflammatory Bowel Disease and Microbiome: Diagnosis and prediction of disease activity from the lab to the patients

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Natalia Borruel Sainz, Francesc Casellas Jordá, Isaac Manjon Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI20/00130
Duration: 01/01/2021 - 31/12/2024

Blog

News

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The European project DISCOvERIE, led by Vall d’Hebron, paves the way for more personalized diagnoses and new treatment strategies to improve patients’ quality of life.

15 researchers from the Rheumatology, Systemic Diseases and the Physiology and Pathophysiology of the Digestive Tract groups gave around 25 presentations.