About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.
Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.
We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function.
PMID: 37992681 Journal: Cell Reports Medicine Year: 2023 Reference: Cell Rep Med. 2023 Nov 21;4(11):101294. doi: 10.1016/j.xcrm.2023.101294. Impact factor: Publication type: Paper in international publication Authors: Macarulla, Teresa; Malagelada, Carolina; Martin Dominguez, Veronica; Santander, Cecilio; Tian, Tian V; Yanez-Bartolome, Mariana et al. DOI: 10.1016/j.xcrm.2023.101294
PMID: 38012160 Journal: Nature Communications Year: 2023 Reference: Nat Commun. 2023 Nov 27;14(1):7770. doi: 10.1038/s41467-023-43652-x. Impact factor: Publication type: Paper in international publication Authors: Alonso, Fabiola; Arpa, Berta; Aunon, Pilar; Corral-Pujol, Marta; Cosovanu, Catalina; Egia-Mendikute, Leire; Garcia, Patricia; Garcia-Carro, Clara; Gutierrez, Eduardo; Manichanh, Chaysavanh et al. DOI: 10.1038/s41467-023-43652-x
PMID: 38023553 Journal: Open Forum Infectious Diseases Year: 2023 Reference: Open Forum Infect Dis. 2023 Oct 31;10(11):ofad542. doi: 10.1093/ofid/ofad542. eCollection 2023 Nov. Impact factor: Publication type: Paper in international publication Authors: Arpa, Berta; Bernal, Enrique; Clotet, Bonaventura; Corral-Pujol, Marta; Cosovanu, Catalina; Curran, Adria; Domingo, Pere; Egia-Mendikute, Leire; Gutierrez, Felix; Imaz, Arkaitz et al. DOI: 10.1093/ofid/ofad542
PMID: 38030035 Journal: JOURNAL OF HEPATOLOGY Year: 2023 Reference: J Hepatol. 2023 Nov 27:S0168-8278(23)05285-6. doi: 10.1016/j.jhep.2023.10.043. Impact factor: Publication type: Paper in international publication Authors: Arijs, Ingrid; Borruel, Natalia; Carney, Nicholas; Casellas, Francesc; Charlafti, Ilias; Ferrante, Marc; Fierens, Liselotte; Fiorino, Gionata; Gerold, Nathalie; Gross, Evelyn et al. DOI: 10.1016/j.jhep.2023.10.043
PMID: 26848957 Journal: PLoS Neglected Tropical Diseases Year: 2016 Reference: PLoS Negl Trop Dis. 2016 Feb 5;10(2):e0004416. doi: 10.1371/journal.pntd.0004416. eCollection 2016 Feb. Impact factor: 3.948 Publication type: Paper in international publication Authors: Moris, Maria, Sanchez-Montalva, Adrian, Accarino, Anna, Ramirez, Kathleen, Azpiroz, Fernando, Ruiz-de-Leon, Antonio, Molina, Israel, Salvador, Fernando, Mego, Marianela et al. DOI: 10.1371/journal.pntd.0004416
Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.
The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.
Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.