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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Team

Mercedes Pallero Castillo

Mercedes Pallero Castillo

Pneumology
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Aljama Vizcarra, Cristina

Aljama Vizcarra, Cristina

Predoctoral researcher
Pneumology
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Carmen Folch Badiella

Carmen Folch Badiella

Research technician
Pneumology
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Clara Pons Boyero

Clara Pons Boyero

Research technician
Pneumology
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David Espejo Castellanos

David Espejo Castellanos

Predoctoral researcher
Pneumology
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De Moner Ferran, Ares

De Moner Ferran, Ares

Research technician
Pneumology
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Mercedes Pallero Castillo

Mercedes Pallero Castillo

Pneumology
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Aljama Vizcarra, Cristina

Aljama Vizcarra, Cristina

Predoctoral researcher
Pneumology
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Carmen Folch Badiella

Carmen Folch Badiella

Research technician
Pneumology
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Clara Pons Boyero

Clara Pons Boyero

Research technician
Pneumology
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David Espejo Castellanos

David Espejo Castellanos

Predoctoral researcher
Pneumology
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De Moner Ferran, Ares

De Moner Ferran, Ares

Research technician
Pneumology
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Research lines

Sleep disorders.

The research effort also focuses on the various diagnostic and therapeutic options for respiratory sleep disorders, and, recently, on the vascular repercussions of these disorders. Currently the Group is participating in several multicenter endeavours in non-invasive mechanical ventilation and in a project financed by the FIS to assess the efficacy of treatment with continuous positive air pressure (CPAP) through a nasal route to reduce arterial pressure values in patients with sleep apnoea and arterial hypertension.

IP: Gabriel Sampol Rubio

Work-related diseases, asthma and fibrosis.

The Group is considered a referral team for the diagnosis and treatment of work-related lung diseases in Catalonia, centring mainly on occupational asthma, hypersensitivity pneumonitis, and occupational disease caused by asbestos exposure. It is responsible for the creation and monitoring of the Spanish Registry of Occupational Diseases (EROL), an important task that had not been covered previously. 


The Group forms a part of the Grup Col.laboratiu per la Investigació de l’Asma per Soja a Barcelona (Collaborative Research Group for Soy Asthma in Barcelona). Moreover, it is an officially accredited center to carry out daily determinations of environmental levels of soy aeroallergens in Barcelona. For this purpose, the Group has an agreement with the Servicio de Medio Ambiente del Puerto de Barcelona (Environmental Service of the Port of Barcelona), which uses the results of these analyses to monitor the unloading of soy products in the city’s port. This daily monitoring of soy aeroallergen in the city has helped the authorities been to eliminate further asthma epidemics The Group has been given several awards for its work in the area of soy asthma, such as the Fundació Cor Vilacasas award (1993), the Science Award of the City of Barcelona (1995), and the Josep Trueta Award from the Acadèmia de Ciències Mèdiques (1995).


The team also has broad experience in the study of hypersensitivity pneumonitis, with a series of 150 patients that is one of the largest in the country, given the low prevalence of this condition. In addition, our center is considered a national referral hospital for the diagnosis and treatment of this pathology. Within the research into occupational disease due to asbestos exposure, our research laboratory is the only one in Spain that carries out determinations of asbestos bodies in the lung.

IP: Fco. Javier Muñoz Gall

Projects

MicroRNA expression profiles in asthmatic patients with different disease phenotypes exposed to pollutants.

IP: Mª Jesús Cruz Carmona
Collaborators: Maria Florencia Pilia, Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 89900
Reference: FI22/00262
Duration: 01/01/2023 - 31/12/2027

TRANS-GENE - Caracterización en Sangre Periférica de una Firma Génica de Rechazo Humoral Común en Trasplantes de Órganos Sólidos.

IP: Maria Antonia Emilia Meneghini
Collaborators: Lluis Castells Fusté, Joana Sellarés Roig, Jesús Quintero Bernabeu, Eva Maria Revilla Lopez, Marina Muñoz López, Meritxell Boada Perez, Laura Donadeu Casassas, Mercedes López González
Funding agency: Instituto de Salud Carlos III
Funding: 111320
Reference: PI22/00749
Duration: 01/01/2023 - 31/12/2025

Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR.

IP: Francesc Xavier Molero Richard
Collaborators: Laura Campderros Traver, Eva Polverino
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI22/00887
Duration: 01/01/2023 - 31/12/2025

BIOMARCADORES NO INVASIVOS DE DISFUNCIÓN CRÓNICA EN TRASPLANTE PULMONAR.

IP: Cristina Berastegui Garcia
Collaborators: Carles Bravo Masgoret, Eva Maria Revilla Lopez, Meritxell Boada Perez, Susana Gómez Olles
Funding agency: Instituto de Salud Carlos III
Funding: 117370
Reference: PI22/01103
Duration: 01/01/2023 - 31/12/2025

Publications

Benefits of a Homecare Integral Patient Support Program in Idiopathic Pulmonary Fibrosis.

PMID: 37003881
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2023
Reference: Arch Bronconeumol. 2023 Aug;59(8):526-530. doi: 10.1016/j.arbres.2023.03.008. Epub 2023 Mar 21.
Impact factor:
Publication type: Letter or abstract
Authors: Arribas, J; Badenes-Bonet, D; Balcells, E; Barril, S; Belmonte, Y; Bermudo, G; Bespin, J; Blavia, R; Boldova, A; Castillo, D et al.
DOI: 10.1016/j.arbres.2023.03.008

CONQUEST: A Quality Improvement Program for Defining and Optimizing Standards of Care for Modifiable High-Risk COPD Patients

PMID: NOPMID0097
Journal: Patient Related Outcome Measures
Year: 2023
Reference: Patient Relat Outcome Meas. 2022;13:53-68. Doi: Patient Relat Outcome Meas. 2022;13:53-68. Doi: 10.2147/PROM.S296506
Impact factor:
Publication type: Review in international publication
Authors: Alves, Luis; Carter, Victoria; Chen, Rongchang; Couper, Amy; Dransfield, Mark; Evans, Alexander; Hardjojo, Antony; Hurst, John R; Jones, David; Jones, Rupert et al.
DOI: 10.2147/PROM.S296506

A case of self-improving collodion ichthyosis associated with a rare variant of the ALOX12B gene.

PMID: 37040911
Journal: Dermatology online journal
Year: 2023
Reference: Dermatol Online J. 2023 Feb 15;29(1). doi: 10.5070/D329160214.
Impact factor:
Publication type: Paper in international publication
Authors: Amoedo, P; Cerejeira, A; Cruz, M J; Mota, A; Pacheco, J et al.
DOI: 10.5070/D329160214

Estimated Worldwide Prevalence of the PI*ZZ Alpha-1 Antitrypsin Genotype in Subjects With Chronic Obstructive Pulmonary Disease.

PMID: 37045725
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2023
Reference: Arch Bronconeumol. 2023 Jul;59(7):427-434. doi: 10.1016/j.arbres.2023.03.016. Epub 2023 Mar 30.
Impact factor:
Publication type: Paper in national publication
Authors: Blanco, Ignacio; Bueno, Patricia; Castanon, Cesar; Diego, Isidro; Miravitlles, Marc et al.
DOI: 10.1016/j.arbres.2023.03.016

Sleep increases leaks and asynchronies during home noninvasive ventilation: a polysomnographic study.

PMID: 34314351
Journal: Journal of Clinical Sleep Medicine
Year: 2022
Reference: J Clin Sleep Med. 2022 Jan 1;18(1):225-233. doi: 10.5664/jcsm.9546.
Impact factor: 4.062
Publication type: Paper in international publication
Authors: Marti, Sergi; Ferre, Alex; Sampol, Gabriel; Pallero, Mercedes; Romero, Odile; Ferrer, Jaume; Sampol, Julia et al.
DOI: 10.5664/jcsm.9546

Reconciling short-term clinical and Immunological outcomes of SARS-CoV-2 vaccination in Solid Organ Transplant recipients.

PMID: 34554648
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5.
Impact factor: 8.086
Publication type: Letter or abstract
Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al.
DOI: 10.1111/ajt.16855

Inhaled Corticosteroid Use Among COPD Patients in Primary Care in Spain.

PMID: 35115771
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2022
Reference: Int J Chron Obstruct Pulmon Dis. 2022 Jan 25;17:245-258. doi: 10.2147/COPD.S342220. eCollection 2022.
Impact factor: 3.355
Publication type: Paper in international publication
Authors: Miravitlles, Marc; Roman-Rodriguez, Miguel; Ribera, Xavier; Ritz, John; Izquierdo, Jose Luis et al.
DOI: 10.2147/COPD.S342220

A comprehensive assessment of long-term SARS-CoV-2-specific adaptive immune memory in convalescent COVID-19 Solid Organ Transplant recipients.

PMID: 35124011
Journal: KIDNEY INTERNATIONAL
Year: 2022
Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4.
Impact factor: 10.612
Publication type: Paper in international publication
Authors: Fava, Alexandre; Donadeu, Laura; Jouve, Thomas; Gonzalez-Costello, Jose; Llado, Laura; Santana, Carolina; Toapanta, Nestor; Lopez, Manuel; Pernin, Vincent; Facundo, Carme et al.
DOI: 10.1016/j.kint.2021.12.029

Can we Train the Immune System of Patients With Cystic Fibrosis?

PMID: 35699016
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):708-710. doi: 10.1016/j.arbr.2020.10.016.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Assante, Giulio, Martinez-Gallo, Monica, Traversi, Letizia, Tur-Torres, Jordi, Romero Mesones, Christian Eduardo, Chang-Macchiu, Patricia, Alvarez, Antoni, Clofent Alarcon, David, Polverino, Eva, Torres-Sierra, Sandra et al.
DOI: 10.1016/j.arbr.2020.10.016

Peribronchovascular emphysema. The Macklin effect.

PMID: 35699007
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):697. doi: 10.1016/j.arbr.2021.09.001. Epub 2021 Sep 20.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Villar, Ana, Granados, Galo, Ferreiro, Antia et al.
DOI: 10.1016/j.arbr.2021.09.001

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry.

PMID: 33540340
Journal: RESPIRATORY MEDICINE
Year: 2021
Reference: Respir Med. 2021 Mar;178:106220. doi: 10.1016/j.rmed.2020.106220. Epub 2020 Nov 12.
Impact factor: 3.415
Publication type: Paper in international publication
Authors: Ulrich, Silvia, Gomez Sanchez, Miguel-Angel, Humbert, Marc, Pittrow, David, Simonneau, Gerald, Gall, Henning, Grunig, Ekkehard, Klose, Hans, Halank, Michael, Langleben, David et al.
DOI: 10.1016/j.rmed.2020.106220

Management of drug toxicity in M. avium complex pulmonary disease - an expert panel survey.

PMID: 32910814
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2021
Reference: Clin Infect Dis. 2021 Jul 1;73(1):e256-e259. doi: 10.1093/cid/ciaa1361.
Impact factor: 8.313
Publication type: Paper in international publication
Authors: Wagner, Dirk, van Ingen, Jakko, Aliberti, Stefano, Andrejak, Claire, Chalmers, James D, Codecasa, Luigi R, Daley, Charles L, Hasegawa, Naoki, Griffith, David E, Hoefsloot, Wouter et al.
DOI: 10.1093/cid/ciaa1361

Factors that determine the loss of control when reducing therapy by steps in the treatment of moderate-severe asthma in standard clinical practice: A multicentre Spanish study.

PMID: 31350049
Journal: REVISTA CLINICA ESPANOLA
Year: 2020
Reference: Rev Clin Esp (Barc). 2020 Mar;220(2):86-93. doi: 10.1016/j.rce.2019.05.004. Epub 2019 Jul 23.
Impact factor: 1.304
Publication type: Paper in national publication
Authors: Santiago, Aparicio Espanol, Marta, Velasco Azagra, Antonio, Alvarez Fernandez Jose, Sara, Acero Sainz, Rosa, Blanco Gonzalez M, Estela, Gomez Nieves Maria, Diego, Aisa Carpio, Nuria, Angrill Selles, Cristina, Berastegui Garcia, Astrid, Crespo Lessmann et al.
DOI: 10.1016/j.rce.2019.05.004

Association between reperfusion therapy and outcomes in patients with acute pulmonary embolism and right heart thrombi.

PMID: 32430430
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2020
Reference: Eur Respir J. 2020 Nov 5;56(5). pii: 13993003.00538-2020. doi: 10.1183/13993003.00538-2020. Print 2020 Nov.
Impact factor: 12.339
Publication type: Letter whit IF
Authors: Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge-Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio et al.
DOI: 10.1183/13993003.00538-2020

A Systematically Derived Exposure Assessment Instrument for Chronic Hypersensitivity Pneumonitis.

PMID: 31958445
Journal: CHEST
Year: 2020
Reference: Chest. 2020 Jun;157(6):1506-1512. doi: 10.1016/j.chest.2019.12.018. Epub 2020 Jan 17.
Impact factor: 8.308
Publication type: Review in international publication
Authors: Barber, Christopher M, Behr, Jurgen, Bonella, Francesco, Corte, Tamera, Costabel, Ulrich, Cottin, Vincent, Crestani, Bruno, Dalphin, Jean-Charles, Flaherty, Kevin R, Goh, Nicole et al.
DOI: 10.1016/j.chest.2019.12.018

The immunomodulatory effects of diesel exhaust particles in asthma.

PMID: 33618472
Journal: ENVIRONMENTAL POLLUTION
Year: 2020
Reference: Environ Pollut. 2020 Aug;263(Pt A):114600. doi: 10.1016/j.envpol.2020.114600. Epub 2020 Apr 20.
Impact factor: 6.792
Publication type: Paper in international publication
Authors: de Homdedeu M, Cruz, Mj, Sanchez-Diez, S, I, Ojanguren, Romero-Mesones, C, J, Vanoirbeek, Velde G, Vande, X, Munoz et al.
DOI: 10.1016/j.envpol.2020.114600

Predictors of 1-year compliance with adaptive servoventilation in patients with heart failure and sleep disordered breathing: preliminary data from the ADVENT-HF trial.

PMID: 30409822
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2019
Reference: Eur Respir J. 2019 Feb 21;53(2). pii: 13993003.01626-2018. doi: 10.1183/13993003.01626-2018. Print 2019 Feb.
Impact factor: 11.807
Publication type: Letter whit IF
Authors: Ryan, C M, Redolfi, S, Parati, G, Arzt, M, Duran Cantolla, J, Kasai, T, Smith, E R, Johnstone, D, Collins, R, Joyner, C et al.
DOI: 10.1183/13993003.01626-2018

Blood eosinophils could be useful as a biomarker in COPD exacerbations.

PMID: 31573721
Journal: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
Year: 2019
Reference: Int J Clin Pract. 2019 Oct 1:e13423. doi: 10.1111/ijcp.13423.
Impact factor: 2.613
Publication type: Paper in international publication
Authors: Gonzalez-Barcala, Francisco-Javier, San-Jose, Maria-Esther, Nieto-Fontarigo, Juan-Jose, Calvo-Alvarez, Uxio, Carreira, Jose-Martin, Garcia-Sanz, Maria-Teresa, Munoz, Xavier, Perez-Lopez-Corona, M P, Gomez-Conde, M J, Casas-Fernandez, A et al.
DOI: 10.1111/ijcp.13423

Community-acquired respiratory viruses are a risk factor for chronic lung allograft dysfunction.

PMID: 30561555
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2019
Reference: Clin Infect Dis. 2019 Sep 13;69(7):1192-1197. doi: 10.1093/cid/ciy1047.
Impact factor: 9.055
Publication type: Paper in international publication
Authors: Ferrer, Ricard, Peghin, Maddalena, Los-Arcos, Ibai, Hirsch, Hans H, Codina, Gemma, Monforte, Victor, Bravo, Carles, Berastegui, Cristina, Jauregui, Alberto, Romero, Laura et al.
DOI: 10.1093/cid/ciy1047

Efficacy and safety of tobramycin inhalation powder in bronchiectasis patients with P. aeruginosa infection: Design of a dose-finding study (iBEST-1).

PMID: 31433997
Journal: PULMONARY PHARMACOLOGY & THERAPEUTICS
Year: 2019
Reference: Pulm Pharmacol Ther. 2019 Oct;58:101834. doi: 10.1016/j.pupt.2019.101834. Epub 2019 Aug 18.
Impact factor: 2.669
Publication type: Paper in international publication
Authors: Loebinger, Michael R, Polverino, Eva, Blasi, Francesco, Elborn, Stuart J, Chalmers, James D, Tiddens, Harm Awm, Goossens, Herman, Tunney, Michael, Zhou, Wenchun, Angyalosi, Gerhild et al.
DOI: 10.1016/j.pupt.2019.101834

QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.

PMID: 29880656
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Aug 16;52(2). pii: 13993003.00537-2018. doi: 10.1183/13993003.00537-2018. Print 2018 Aug.
Impact factor: 12.242
Publication type: Letter or abstract
Authors: Burman, Matthew, Guglielmetti, Lorenzo, Tiberi, Simon, Kristjansson, Mar, McLaughlin, Anne Marie, Chiappini, Elena, Confalonieri, Marco, Del Bravo, Paola, Gualano, Gina, Motta, Ilaria et al.
DOI: 10.1183/13993003.00537-2018

Study of CD27 and CCR4 Markers on Specific CD4(+) T-Cells as Immune Tools for Active and Latent Tuberculosis Management.

PMID: 30687314
Journal: Frontiers in Immunology
Year: 2018
Reference: Front Immunol. 2019 Jan 9;9:3094. doi: 10.3389/fimmu.2018.03094. eCollection 2018.
Impact factor: 5.511
Publication type: Paper in international publication
Authors: Prat, Cristina, Dominguez, Jose, Sabria, Josefina, Luque-Chacon, Lydia, Lacoma, Alicia, Gonzalez-Diaz, Yoel D, Latorre, Irene, Muriel-Moreno, Beatriz, Villar-Hernandez, Raquel, Vila, Sergi et al.
DOI: 10.3389/fimmu.2018.03094

Asbestos-Related disease in upholsterers.

PMID: 28686522
Journal: Archives of Environmental & Occupational Health
Year: 2018
Reference: Arch Environ Occup Health. 2018 May 4;73(3):186-188. doi: 10.1080/19338244.2017.1350133. Epub 2017 Jul 31.
Impact factor: 1.347
Publication type: Paper in international publication
Authors: Cruz, M J, Sampol, J, Pallero, M, Rodriguez, E, Ferrer, J et al.
DOI: 10.1080/19338244.2017.1350133

Duration of the efficacy of omalizumab after treatment discontinuation in 'real life' severe asthma.

PMID: 29079610
Journal: THORAX
Year: 2018
Reference: Thorax. 2018 Aug;73(8):782-784. doi: 10.1136/thoraxjnl-2017-210017. Epub 2017 Oct 27.
Impact factor: 9.655
Publication type: Letter or abstract
Authors: Vennera, Maria Del Carmen, Sabadell, Carlos, Picado, Cesar, Alvarez Puebla, M J, Irigaray, R, Martinez-Moragon, E, Pellicer, C, Martinez, C, Munoz, X, Canete, C et al.
DOI: 10.1136/thoraxjnl-2017-210017

Lorraine Racusen and Kim Solez Awarded the Gold Medal of the Catalan Transplant Society.

PMID: 29198652
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2240-2242. doi: 10.1016/j.transproceed.2017.09.044.
Impact factor: 0.908
Publication type: Letter or abstract
Authors: Seron, D, Roman, A et al.
DOI: 10.1016/j.transproceed.2017.09.044

Epidemiology and Risk Factors for Cancer After Lung Transplantation.

PMID: 29198662
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2285-2291. doi: 10.1016/j.transproceed.2017.09.043.
Impact factor: 0.908
Publication type: Paper in international publication
Authors: Berastegui, C, LaPorta, R, Lopez-Meseguer, M, Romero, L, Gomez-Olles, S, Riera, J, Monforte, V, Saez, B, Bravo, C, Roman, A et al.
DOI: 10.1016/j.transproceed.2017.09.043

BANFF-CATALAN TRANSPLANTATION SOCIETY JOINT SCIENTIFIC MEETING Preface Foreword

PMID: 29198651
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2239. doi: 10.1016/j.transproceed.2017.10.012.
Impact factor: 0.908
Publication type: Letter or abstract
Authors: Roman, Antonio, Solez, Kim, Mengel, Michael, Seron, Daniel et al.
DOI: 10.1016/j.transproceed.2017.10.012

Lung and heart-lung transplantation in pulmonary arterial hypertension.

PMID: 29161284
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Nov 21;12(11):e0187811. doi: 10.1371/journal.pone.0187811. eCollection 2017.
Impact factor: 2.806
Publication type: Paper in international publication
Authors: Lopez-Meseguer, Manuel, Quezada, Carlos A, Ramon, Maria A, Lazaro, Maria, Dos, Laura, Lara, Antonio, Lopez, Raquel, Blanco, Isabel, Roman, Antonio, Escribano, Pilar et al.
DOI: 10.1371/journal.pone.0187811

Primary Graft Dysfunction and Mortality Following Lung Transplantation: A Role for Proadrenomedullin Plasma Levels.

PMID: 26461449
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2016
Reference: Am J Transplant. 2016 Feb;16(2):634-9. doi: 10.1111/ajt.13478. Epub 2015 Oct 13.
Impact factor: 5.669
Publication type: Paper in international publication
Authors: Baldira, Jaume, Maldonado, Carolina, Lagunes, Leonel, Moyano, Silvia, Rull, Elisenda, Pont, Teresa, Sandiumenge, Albert, Rochera, Maria Isabel, Ribas, Montse, Ruiz, Daniel et al.
DOI: 10.1111/ajt.13478

Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations.

PMID: 27132815
Journal: Transplantation Reviews
Year: 2016
Reference: Transplant Rev (Orlando). 2016 Jul;30(3):119-43. doi: 10.1016/j.trre.2016.04.001. Epub 2016 Apr 29.
Impact factor: 3.915
Publication type: Review in national publication
Authors: Aguado, J M, Caston, J J, Almenar, L, Alonso, A, Cantisan, S, Carratala, J, Cervera, C, Cordero, E, Farinas, M C, Fernandez-Ruiz, M et al.
DOI: 10.1016/j.trre.2016.04.001

Molecular Analysis of BMPR2, TBX4, and KCNK3 and Genotype-Phenotype Correlations in Spanish Patients and Families With Idiopathic and Hereditary Pulmonary Arterial Hypertension.

PMID: 27453251
Journal: Revista espanola de cardiologia (English ed.)
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 Nov;69(11):1011-1019. doi: 10.1016/j.rec.2016.03.029. Epub 2016 Jul 21.
Impact factor: 4.596
Publication type: Paper in national publication
Authors: Navas, Paula, Tenorio, Jair, Quezada, Carlos Andres, Barrios, Elvira, Gordo, Gema, Lopez Meseguer, Manuel, Santos-Lozano, Alejandro, Palomino Doza, Julian, Lapunzina, Pablo, Escribano Subias, Pilar et al.
DOI: 10.1016/j.rec.2016.03.029

Relationships between chronic obstructive pulmonary disease and lung cancer: biological insights.

PMID: 27867578
Journal: Journal of Thoracic Disease
Year: 2016
Reference: J Thorac Dis. 2016 Oct;8(10):E1122-E1135.
Impact factor: 1.649
Publication type: Review in national publication
Authors: Barreiro, Esther, Bustamante, Victor, Curull, Victor, Gea, Joaquim, Lopez-Campos, Jose Luis, Munoz, Xavier et al.
DOI: 10.21037/jtd.2016.09.54

A founder EIF2AK4 mutation causes an aggressive form of pulmonary arterial hypertension in Iberian Gypsies.

PMID: 25512148
Journal: CLINICAL GENETICS
Year: 2015
Reference: Clin Genet. 2015 Dec;88(6):579-83. doi: 10.1111/cge.12549. Epub 2015 Jan 7.
Impact factor: 3.931
Publication type: Paper in international publication
Authors: Tenorio, J, Navas, P, Barrios, E, Fernandez, L, Nevado, J, Quezada, C A, Lopez-Meseguer, M, Arias, P, Mena, R, Lobo, J L et al.
DOI: 10.1111/cge.12549

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness.

PMID: 26167915
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 Jul 13;10(7):e0132546. doi: 10.1371/journal.pone.0132546. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Ruiz de Garibay, Gorka, Herranz, Carmen, Llorente, Alicia, Gil, Miguel, Roman, Antonio, Molina-Molina, Maria, Ussetti, Piedad, Laporta, Rosalia, Valenzuela, Claudia, Ancochea, Julio et al.
DOI: 10.1371/journal.pone.0132546

Management of pulmonary exacerbations in cystic fibrosis: still an unmet medical need in clinical practice.

PMID: 25692532
Journal: Expert Review of Medical Devices
Year: 2015
Reference: Expert Rev Respir Med. 2015 Apr;9(2):183-94. doi: 10.1586/17476348.2015.1016504. Epub 2015 Feb 18.
Impact factor: 1.683
Publication type: Review in national publication
Authors: Justicia, Jose Luis, Sole, Amparo, Quintana-Gallego, Esther, Gartner, Silvia, de Gracia, Javier, Prados, Concepcion, Maiz, Luis et al.
DOI: 10.1586/17476348.2015.1016504

Prevalence and Diagnosis of Chronic Kidney Disease in Maintenance Lung Transplant Patients: ICEBERG Study.

PMID: 26293082
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2015
Reference: Transplant Proc. 2015 Jul-Aug;47(6):1966-71. doi: 10.1016/j.transproceed.2015.04.097.
Impact factor: 0.982
Publication type: Paper in international publication
Authors: Sole, A, Zurbano, F, Borro, J M, Monforte, V, Ussetti, P, Santos, F et al.
DOI: 10.1016/j.transproceed.2015.04.097

[Immunological studies and specific bronchial challenge tests, essential techniques for the diagnosis of hypersensitivity pneumonitis.]

PMID: 24315749
Journal: MED CLIN-BARCELONA
Year: 2014
Reference: Med Clin (Barc). 2014 Oct 7;143(7):328-9. doi: 10.1016/j.medcli.2013.09.029. Epub 2013 Dec 5.
Impact factor: 1.399
Publication type: Letter whit IF
Authors: Cruz, Maria Jesus, Alvarez-Simon, Daniel, Gomez-Olles, Susana, Munoz, Xavier et al.
DOI: 10.1016/j.medcli.2013.09.029

The unresolved issue of oxygen therpay in lung fibrosis: Some clues from a Spanish cohort

PMID: 91000008
Journal: Journal of Clinical & Experimental Research
Year: 2014
Reference: Am J Exp Clin Res 2014;1(1):6-10
Impact factor:
Publication type: Letter or abstract
Authors: Moreno, A, Vicens-Zygmunt, V, Villar, A, Marín, A, Cano, E, Robles, A, Xaubet, A, Martí, S, Castillo, D, Molina, M et al.
DOI:

Specific inhalation challenge tests for occupational asthma in Europe: a survey.

PMID: 24881084
Journal: European Respiratory Review
Year: 2014
Reference: Eur Respir Rev. 2014 Jun;23(132):266-70. doi: 10.1183/09059180.00000414.
Impact factor:
Publication type: Letter or abstract
Authors: Suojalehto, Hille, Cullinan, Paul, Muñoz, X et al.
DOI: 10.1183/09059180.00000414

Work-related asthma: diagnosis and prognosis of immunological occupational asthma and work-exacerbated asthma.

PMID: 25668891
Journal: J INVEST ALLERG CLIN
Year: 2014
Reference: J Investig Allergol Clin Immunol. 2014;24(6):396-405.
Impact factor: 2.642
Publication type: Review in national publication
Authors: Munoz, X, Cruz, M J, Bustamante, V, Lopez-Campos, J L, Barreiro, E et al.
DOI:

Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial.

PMID: 24327037
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2013
Reference: JAMA. 2013 Dec 11;310(22):2407-15. doi: 10.1001/jama.2013.281250.
Impact factor: 29.978
Publication type: Paper in international publication
Authors: Montserrat, Josep Maria, Capote, Francisco, Campos-Rodriguez, Francisco, Lloberes, Patricia, Diaz de Atauri, Maria Josefa, Somoza, Maria, Masa, Juan F, Gonzalez, Monica, Sacristan, Lirios, Barbe, Ferran et al.
DOI: 10.1001/jama.2013.281250

Pulmonary vascular abnormalities in chronic obstructive pulmonary disease undergoing lung transplant.

PMID: 24263025
Journal: JOURNAL OF HEART AND LUNG TRANSPLANTATION
Year: 2013
Reference: J Heart Lung Transplant. 2013 Dec;32(12):1262-9. doi: 10.1016/j.healun.2013.09.007.
Impact factor: 5.112
Publication type: Paper in international publication
Authors: Peinado, Victor I, Gomez, Federico P, Barbera, Joan Albert, Roman, Antonio, Angels Montero, M, Ramirez, Josep, Roca, Josep, Rodriguez-Roisin, Roberto et al.
DOI: 10.1016/j.healun.2013.09.007

[Strokes and their relationship with sleep and sleep disorders.]

PMID: 21163212
Journal: NEUROLOGIA
Year: 2013
Reference: Neurologia. 2013 Mar;28(2):103-18. doi: 10.1016/j.nrl.2010.09.016. Epub 2010 Nov 19.
Impact factor: 1.322
Publication type: Review in national publication
Authors: , , , , , , et al.
DOI: 10.1016/j.nrl.2010.09.016

Sputum inflammatory profile before and after specific inhalation challenge in individuals with suspected occupational asthma.

PMID: 24236015
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Nov 13;8(11):e78304. doi: 10.1371/journal.pone.0078304.
Impact factor: 3.73
Publication type: Paper in international publication
Authors: Munoz, Xavier, Morell, Ferran, Gomez-Olles, Susana, Cruz, Maria-Jesus, Sanchez-Vidaurre, Sara et al.
DOI: 10.1371/journal.pone.0078304

Genetic-based reference values for angiotensin-converting enzyme (ACE) according to I/D polymorphism in a Spanish population sample.

PMID: 23089703
Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Year: 2012
Reference: Clin Chem Lab Med. 2012 Oct 1;50(10):1749-53. doi: 10.1515/cclm-2012-0042.
Impact factor: 2.15
Publication type: Paper in international publication
Authors: Camos, Silvia, Cruz, M Jesus, Sole, Esther, Morell, Ferran et al.
DOI: 10.1515/cclm-2012-0042

TACI mutation in Good's Syndrome: In search of a genetic basis.

PMID: 22922270
Journal: CLINICAL IMMUNOLOGY
Year: 2012
Reference: Clin Immunol. 2012 Oct;145(1):27-30. doi: 10.1016/j.clim.2012.07.014. Epub 2012 Aug 4.
Impact factor: 4.046
Publication type: Letter whit IF
Authors: Saenz-Cuesta, Matias, Martinez-Pomar, Natalia, de Gracia, Javier, Echaniz, Pilar, Villegas, Eduardo, Prada, Alvaro, Otaegui, David, Matamoros, Nuria, Cuadrado, Emilio et al.
DOI: 10.1016/j.clim.2012.07.014

Bronchial inflammation and hyperresponsiveness in well controlled asthma.

PMID: 22925318
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2012
Reference: Clin Exp Allergy. 2012 Sep;42(9):1321-8. doi: 10.1111/j.1365-2222.2012.04004.x.
Impact factor: 5.032
Publication type: Paper in international publication
Authors: Munoz, X, Sanchez-Vidaurre, S, Roca, O, Torres, F, Morell, F, Cruz, M J et al.
DOI: 10.1111/j.1365-2222.2012.04004.x

Omalizumab therapy in severe asthma: experience from the Spanish registry--some new approaches.

PMID: 22443408
Journal: JOURNAL OF ASTHMA
Year: 2012
Reference: J Asthma. 2012 May;49(4):416-22. Epub 2012 Mar 23.
Impact factor: 1.525
Publication type: Paper in international publication
Authors: Vennera, Maria Del Carmen, Perez De Llano, Luis, Bardagi, Santiago, Ausin, Pilar, Sanjuas, Carles, Gonzalez, Hector, Gullon, Jose A, Martinez-Moragon, Eva, Carretero, Jose A, Serrano, Jose et al.
DOI: 10.3109/02770903.2012.668255

Efficacy and safety of Hizentra((R)) in patients with primary immunodeficiency after a dose-equivalent switch from intravenous or subcutaneous replacement therapy.

PMID: 21705277
Journal: CLINICAL IMMUNOLOGY
Year: 2011
Reference: Clin Immunol. 2011 Oct;141(1):90-102. Epub 2011 Jun 12.
Impact factor: 3.932
Publication type: Paper in international publication
Authors: Jolles, S, Bernatowska, E, de Gracia, J, Borte, M, Cristea, V, Peter, H H, Wahn, V, Neufang-Huber, J, Zenker, O, Grimbacher, B et al.
DOI: 10.1016/j.clim.2011.06.002

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials.

PMID: 21571362
Journal: LANCET
Year: 2011
Reference: Lancet. 2011 May 21;377(9779):1760-9. Epub 2011 May 13.
Impact factor: 33.633
Publication type: Paper in international publication
Authors: Duarte, A, Glassberg, Marilyn K, Kardatzke, David, King, Talmadge E Jr, Lancaster, Lisa, Sahn, Steven A, Szwarcberg, Javier, Valeyre, Dominique, du Bois, Roland M, Agostini, C et al.
DOI: 10.1016/S0140-6736(11)60405-4

GESITRA-SEIMC/REIPI recommendations for the management of cytomegalovirus infection in solid-organ transplant patients.

PMID: 21925772
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2011
Reference: Enferm Infecc Microbiol Clin. 2011 Dec;29(10):735-58. Epub 2011 Sep 17.
Impact factor: 1.656
Publication type: Paper in national publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.eimc.2011.05.022

A retrospective 12-month study of conversion to everolimus in lung transplant recipients.

PMID: 21911148
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2011
Reference: Transplant Proc. 2011 Sep;43(7):2693-8.
Impact factor: 0.993
Publication type: Paper in international publication
Authors: Roman, A, Ussetti, P, Zurbano, F, Borro, J M, Sole, A, Carreno, M C, Santos, F et al.
DOI: 10.1016/j.transproceed.2011.06.028

[Starling-induced hypersensitivity pneumonitis: minimal but persistent antigen exposure].

PMID: 20044195
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2010
Reference: Arch Bronconeumol. 2010 Nov;46(11):607-9. Epub 2009 Dec 30.
Impact factor: 2.166
Publication type: Paper in national publication
Authors: Borderias, Luis, Morell, Ferran, Vera, Jesus, Briz, Helena, Munoz, Xavier, Cruz, Maria Jesus et al.
DOI: 10.1016/j.arbres.2009.10.009

Reported occupational respiratory diseases in three Spanish regions.

PMID: 20583130
Journal: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
Year: 2010
Reference: Am J Ind Med. 2010 Sep;53(9):922-30.
Impact factor: 1.721
Publication type: Paper in international publication
Authors: Michel De La Rosa, F J, Munoz, X, Pascal, I, Panades, R, Perez De Las Casas, M, Rodriguez-Bayarri, M J, Rubira, N, Tabar, A, Marin, B, Lopez, F et al.
DOI: 10.1002/ajim.20862

[Sputum induction in children: Technical development].

PMID: 20138598
Journal: ANALES DE PEDIATRIA
Year: 2010
Reference: An Pediatr (Barc). 2010 Mar;72(3):199-204. Epub 2010 Feb 6.
Impact factor: 0.363
Publication type: Paper in national publication
Authors: Vizmanos Lamotte, G, Moreno Galdo, A, Cruz Carmona, M J, Munoz Gall, X, Gomez Olles, S, de Mir Messa, I, Gartner, S, Martin de Vicente, C et al.
DOI: 10.1016/j.anpedi.2009.10.020

Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial.

PMID: 21106625
Journal: BRITISH MEDICAL JOURNAL
Year: 2010
Reference: BMJ. 2010 Nov 24;341:c5991. doi: 10.1136/bmj.c5991.
Impact factor: 13.66
Publication type: Paper in international publication
Authors: Mayos, Mercedes, Barbe, Ferran, Lopez-Picado, Amanda, Miranda-Serrano, Erika, Martinez-Null, Cristina, Rubio, Ramon, Alonso, Maria Luz, Cordero, Jose, Esteban, Cristobal, Jimenez, Antonio et al.
DOI: 10.1136/bmj.c5991

Lymphangioleiomyomatosis: a study of 72 patients from the Spanish registry.

PMID: 20560288
Journal: SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES
Year: 2009
Reference: Sarcoidosis Vasc Diffuse Lung Dis. 2009 Jul;26(2):85-91.
Impact factor: 1.267
Publication type: Paper in international publication
Authors: Ancochea, J, Giron, R M, Morell, F, Sueiro, A, Anton, E, Casanova, A, Xaubet, A, Roman, A, Villena, V, Montero, M C et al.
DOI:

Platelet Thromboembolism after Lung Transplantation.

PMID: 20130776
Journal: J Transplant
Year: 2009
Reference: J Transplant. 2009;2009:650703.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , , , , , et al.
DOI: 10.1155/2009/650703

An official ATS proceedings: asthma in the workplace: the Third Jack Pepys Workshop on Asthma in the Workplace: answered and unanswered questions.

PMID: 19675344
Journal: Proc Am Thorac Soc
Year: 2009
Reference: Proc Am Thorac Soc. 2009 Aug 1;6(4):339-49.
Impact factor:
Publication type: Letter or abstract
Authors: Bernstein, I L, Tarlo, Susan M, Malo, Jean-Luc, Anto, J, Bacon, S, Beach, J, Becklake, M, Bernstein, D, Mapp, C, Martin, J et al.
DOI: 10.1513/pats.200810-119ST

Health-related Quality of Life before and after a solid organ transplantation (kidney, liver, and lung) of four Catalonia hospitals.

PMID: 19715893
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2009
Reference: Transplant Proc. 2009 Jul-Aug;41(6):2265-7.
Impact factor: 1.055
Publication type: Paper in international publication
Authors: Ortega, F, Twose, J, Cofan, F, Casanovas, T, Garcia, O, Ortega, T, Deulofeu, R, Salamero, P, Roman, A, Masnou, N et al.
DOI: 10.1016/j.transproceed.2009.06.175

Thesis

Biomarcadores en linfangioleiomiomatosis

PhD student: Eva Maria Revilla Lopez, Eva Maria Revilla Lopez
Director/s: Susana Gómez Olles, Berta Saez Gimenez
University: Universitat Autònoma de Barcelona
Year: 2023

Actualización del algoritmo de diagnóstico de laboratorio del déficit de alfa-1-antitripsina: incorporación de la detección genotípica de la variante deficitaria Mmalton y utilización de muestras alternativas a la sangre total

PhD student: Irene Belmonte Mula
Director/s: Marc Miravitlles Fernández, Francisco Rodríguez Frias
University: Universidad Autònoma de Barcelona
Year: 2017

Effect of environmental pollution on asthma due to soybean

PhD student: Daniel Álvarez Simón
Director/s: Mª Jesús Cruz Carmona, Fco. Javier Muñoz Gall
University: Universidad Autònoma de Barcelona
Year: 2017

Eficacia de la fisioterapia respiratoria en pacientes con bronquiectasias

PhD student: Gerard Muñoz Castro
Director/s: Javier de Gracia Roldán
University: Universidad Autònoma de Barcelona
Year: 2017

Farmacocinética de los inhibidores de la calcineurina en el trasplante pulmonar de adultos

PhD student: Maria Alejandra Méndez Garrido
Director/s: Antonio Román Broto, Victor Monforte Torres
University: Universidad Autònoma de Barcelona
Year: 2015

Blog

News

Vall d'Hebron participated in the study in which more than half of the patients who received treatment with bacteriophages experienced significant improvements

La recerca és fonamental per contrarestar els efectes de la pol·lució, que segons l’AEMPS, va ser la causa de més de 300.000 morts prematures a la UE el 2020.

Pulmonary hypertension is a risk factor for patients who need surgery and, therefore, defining strategies for its management is important to allow a favorable clinical evolution.

Job offers

Nurse-Pulmonology research group.
Start date:
06/03/2023
End date:
20/03/2023
Document: Download
Post-doctoral clinical researcher - Pneumology.
Start date:
09/02/2023
End date:
23/02/2023
Document: Download
Data Manager to work in the Asthma and Pulmonary fibrosis program-Pneumology Group.
Start date:
18/01/2023
End date:
01/02/2023
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EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.