About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.
The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.
Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.
The research effort also focuses on the various diagnostic and therapeutic options for respiratory sleep disorders, and, recently, on the vascular repercussions of these disorders. Currently the Group is participating in several multicenter endeavours in non-invasive mechanical ventilation and in a project financed by the FIS to assess the efficacy of treatment with continuous positive air pressure (CPAP) through a nasal route to reduce arterial pressure values in patients with sleep apnoea and arterial hypertension.
IP: Gabriel Sampol Rubio
The Group is considered a referral team for the diagnosis and treatment of work-related lung diseases in Catalonia, centring mainly on occupational asthma, hypersensitivity pneumonitis, and occupational disease caused by asbestos exposure. It is responsible for the creation and monitoring of the Spanish Registry of Occupational Diseases (EROL), an important task that had not been covered previously.
The Group forms a part of the Grup Col.laboratiu per la Investigació de l’Asma per Soja a Barcelona (Collaborative Research Group for Soy Asthma in Barcelona). Moreover, it is an officially accredited center to carry out daily determinations of environmental levels of soy aeroallergens in Barcelona. For this purpose, the Group has an agreement with the Servicio de Medio Ambiente del Puerto de Barcelona (Environmental Service of the Port of Barcelona), which uses the results of these analyses to monitor the unloading of soy products in the city’s port. This daily monitoring of soy aeroallergen in the city has helped the authorities been to eliminate further asthma epidemics The Group has been given several awards for its work in the area of soy asthma, such as the Fundació Cor Vilacasas award (1993), the Science Award of the City of Barcelona (1995), and the Josep Trueta Award from the Acadèmia de Ciències Mèdiques (1995).
The team also has broad experience in the study of hypersensitivity pneumonitis, with a series of 150 patients that is one of the largest in the country, given the low prevalence of this condition. In addition, our center is considered a national referral hospital for the diagnosis and treatment of this pathology. Within the research into occupational disease due to asbestos exposure, our research laboratory is the only one in Spain that carries out determinations of asbestos bodies in the lung.
IP: Fco. Javier Muñoz Gall
IP: Mª Jesús Cruz Carmona Collaborators: Maria Florencia Pilia, Judit Álvarez González Funding agency: Instituto de Salud Carlos III Funding: 89900 Reference: FI22/00262 Duration: 01/01/2023 - 31/12/2027
IP: Maria Antonia Emilia Meneghini Collaborators: Lluis Castells Fusté, Joana Sellarés Roig, Jesús Quintero Bernabeu, Eva Maria Revilla Lopez, Marina Muñoz López, Meritxell Boada Perez, Laura Donadeu Casassas Funding agency: Instituto de Salud Carlos III Funding: 111320 Reference: PI22/00749 Duration: 01/01/2023 - 31/12/2025
IP: - Collaborators: Laura Campderros Traver, Eva Polverino Funding agency: Instituto de Salud Carlos III Funding: 147620 Reference: PI22/00887 Duration: 01/01/2023 - 31/12/2025
IP: Cristina Berastegui Garcia Collaborators: Carles Bravo Masgoret, Eva Maria Revilla Lopez, Meritxell Boada Perez, Susana Gómez Olles Funding agency: Instituto de Salud Carlos III Funding: 117370 Reference: PI22/01103 Duration: 01/01/2023 - 31/12/2025
PMID: 37003881 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2023 Reference: Arch Bronconeumol. 2023 Aug;59(8):526-530. doi: 10.1016/j.arbres.2023.03.008. Epub 2023 Mar 21. Impact factor: Publication type: Letter or abstract Authors: Arribas, J; Badenes-Bonet, D; Balcells, E; Barril, S; Belmonte, Y; Bermudo, G; Bespin, J; Blavia, R; Boldova, A; Castillo, D et al. DOI: 10.1016/j.arbres.2023.03.008
PMID: NOPMID0097 Journal: Patient Related Outcome Measures Year: 2023 Reference: Patient Relat Outcome Meas. 2022;13:53-68. Doi: Patient Relat Outcome Meas. 2022;13:53-68. Doi: 10.2147/PROM.S296506 Impact factor: Publication type: Review in international publication Authors: Alves, Luis; Carter, Victoria; Chen, Rongchang; Couper, Amy; Dransfield, Mark; Evans, Alexander; Hardjojo, Antony; Hurst, John R; Jones, David; Jones, Rupert et al. DOI: 10.2147/PROM.S296506
PMID: 37040911 Journal: Dermatology online journal Year: 2023 Reference: Dermatol Online J. 2023 Feb 15;29(1). doi: 10.5070/D329160214. Impact factor: Publication type: Paper in international publication Authors: Amoedo, P; Cerejeira, A; Cruz, M J; Mota, A; Pacheco, J et al. DOI: 10.5070/D329160214
PMID: 37045725 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2023 Reference: Arch Bronconeumol. 2023 Jul;59(7):427-434. doi: 10.1016/j.arbres.2023.03.016. Epub 2023 Mar 30. Impact factor: Publication type: Paper in national publication Authors: Blanco, Ignacio; Bueno, Patricia; Castanon, Cesar; Diego, Isidro; Miravitlles, Marc et al. DOI: 10.1016/j.arbres.2023.03.016
PMID: 34314351 Journal: Journal of Clinical Sleep Medicine Year: 2022 Reference: J Clin Sleep Med. 2022 Jan 1;18(1):225-233. doi: 10.5664/jcsm.9546. Impact factor: 4.062 Publication type: Paper in international publication Authors: Marti, Sergi; Ferre, Alex; Sampol, Gabriel; Pallero, Mercedes; Romero, Odile; Ferrer, Jaume; Sampol, Julia et al. DOI: 10.5664/jcsm.9546
PMID: 34554648 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2022 Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5. Impact factor: 8.086 Publication type: Letter or abstract Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al. DOI: 10.1111/ajt.16855
PMID: 35115771 Journal: International Journal of Chronic Obstructive Pulmonary Disease Year: 2022 Reference: Int J Chron Obstruct Pulmon Dis. 2022 Jan 25;17:245-258. doi: 10.2147/COPD.S342220. eCollection 2022. Impact factor: 3.355 Publication type: Paper in international publication Authors: Miravitlles, Marc; Roman-Rodriguez, Miguel; Ribera, Xavier; Ritz, John; Izquierdo, Jose Luis et al. DOI: 10.2147/COPD.S342220
PMID: 35124011 Journal: KIDNEY INTERNATIONAL Year: 2022 Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4. Impact factor: 10.612 Publication type: Paper in international publication Authors: Fava, Alexandre; Donadeu, Laura; Jouve, Thomas; Gonzalez-Costello, Jose; Llado, Laura; Santana, Carolina; Toapanta, Nestor; Lopez, Manuel; Pernin, Vincent; Facundo, Carme et al. DOI: 10.1016/j.kint.2021.12.029
PMID: 35699016 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 Nov;57(11):708-710. doi: 10.1016/j.arbr.2020.10.016. Impact factor: 4.872 Publication type: Letter or abstract Authors: Assante, Giulio, Martinez-Gallo, Monica, Traversi, Letizia, Tur-Torres, Jordi, Romero Mesones, Christian Eduardo, Chang-Macchiu, Patricia, Alvarez, Antoni, Clofent Alarcon, David, Polverino, Eva, Torres-Sierra, Sandra et al. DOI: 10.1016/j.arbr.2020.10.016
PMID: 35699007 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 Nov;57(11):697. doi: 10.1016/j.arbr.2021.09.001. Epub 2021 Sep 20. Impact factor: 4.872 Publication type: Paper in international publication Authors: Villar, Ana, Granados, Galo, Ferreiro, Antia et al. DOI: 10.1016/j.arbr.2021.09.001
PMID: 33540340 Journal: RESPIRATORY MEDICINE Year: 2021 Reference: Respir Med. 2021 Mar;178:106220. doi: 10.1016/j.rmed.2020.106220. Epub 2020 Nov 12. Impact factor: 3.415 Publication type: Paper in international publication Authors: Ulrich, Silvia, Gomez Sanchez, Miguel-Angel, Humbert, Marc, Pittrow, David, Simonneau, Gerald, Gall, Henning, Grunig, Ekkehard, Klose, Hans, Halank, Michael, Langleben, David et al. DOI: 10.1016/j.rmed.2020.106220
PMID: 32910814 Journal: CLINICAL INFECTIOUS DISEASES Year: 2021 Reference: Clin Infect Dis. 2021 Jul 1;73(1):e256-e259. doi: 10.1093/cid/ciaa1361. Impact factor: 8.313 Publication type: Paper in international publication Authors: Wagner, Dirk, van Ingen, Jakko, Aliberti, Stefano, Andrejak, Claire, Chalmers, James D, Codecasa, Luigi R, Daley, Charles L, Hasegawa, Naoki, Griffith, David E, Hoefsloot, Wouter et al. DOI: 10.1093/cid/ciaa1361
PMID: 31350049 Journal: REVISTA CLINICA ESPANOLA Year: 2020 Reference: Rev Clin Esp (Barc). 2020 Mar;220(2):86-93. doi: 10.1016/j.rce.2019.05.004. Epub 2019 Jul 23. Impact factor: 1.304 Publication type: Paper in national publication Authors: Santiago, Aparicio Espanol, Marta, Velasco Azagra, Antonio, Alvarez Fernandez Jose, Sara, Acero Sainz, Rosa, Blanco Gonzalez M, Estela, Gomez Nieves Maria, Diego, Aisa Carpio, Nuria, Angrill Selles, Cristina, Berastegui Garcia, Astrid, Crespo Lessmann et al. DOI: 10.1016/j.rce.2019.05.004
PMID: 32430430 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2020 Reference: Eur Respir J. 2020 Nov 5;56(5). pii: 13993003.00538-2020. doi: 10.1183/13993003.00538-2020. Print 2020 Nov. Impact factor: 12.339 Publication type: Letter whit IF Authors: Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge-Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio et al. DOI: 10.1183/13993003.00538-2020
PMID: 31958445 Journal: CHEST Year: 2020 Reference: Chest. 2020 Jun;157(6):1506-1512. doi: 10.1016/j.chest.2019.12.018. Epub 2020 Jan 17. Impact factor: 8.308 Publication type: Review in international publication Authors: Barber, Christopher M, Behr, Jurgen, Bonella, Francesco, Corte, Tamera, Costabel, Ulrich, Cottin, Vincent, Crestani, Bruno, Dalphin, Jean-Charles, Flaherty, Kevin R, Goh, Nicole et al. DOI: 10.1016/j.chest.2019.12.018
PMID: 33618472 Journal: ENVIRONMENTAL POLLUTION Year: 2020 Reference: Environ Pollut. 2020 Aug;263(Pt A):114600. doi: 10.1016/j.envpol.2020.114600. Epub 2020 Apr 20. Impact factor: 6.792 Publication type: Paper in international publication Authors: de Homdedeu M, Cruz, Mj, Sanchez-Diez, S, I, Ojanguren, Romero-Mesones, C, J, Vanoirbeek, Velde G, Vande, X, Munoz et al. DOI: 10.1016/j.envpol.2020.114600
PMID: 30409822 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2019 Reference: Eur Respir J. 2019 Feb 21;53(2). pii: 13993003.01626-2018. doi: 10.1183/13993003.01626-2018. Print 2019 Feb. Impact factor: 11.807 Publication type: Letter whit IF Authors: Ryan, C M, Redolfi, S, Parati, G, Arzt, M, Duran Cantolla, J, Kasai, T, Smith, E R, Johnstone, D, Collins, R, Joyner, C et al. DOI: 10.1183/13993003.01626-2018
PMID: 31573721 Journal: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE Year: 2019 Reference: Int J Clin Pract. 2019 Oct 1:e13423. doi: 10.1111/ijcp.13423. Impact factor: 2.613 Publication type: Paper in international publication Authors: Gonzalez-Barcala, Francisco-Javier, San-Jose, Maria-Esther, Nieto-Fontarigo, Juan-Jose, Calvo-Alvarez, Uxio, Carreira, Jose-Martin, Garcia-Sanz, Maria-Teresa, Munoz, Xavier, Perez-Lopez-Corona, M P, Gomez-Conde, M J, Casas-Fernandez, A et al. DOI: 10.1111/ijcp.13423
PMID: 30561555 Journal: CLINICAL INFECTIOUS DISEASES Year: 2019 Reference: Clin Infect Dis. 2019 Sep 13;69(7):1192-1197. doi: 10.1093/cid/ciy1047. Impact factor: 9.055 Publication type: Paper in international publication Authors: Ferrer, Ricard, Peghin, Maddalena, Los-Arcos, Ibai, Hirsch, Hans H, Codina, Gemma, Monforte, Victor, Bravo, Carles, Berastegui, Cristina, Jauregui, Alberto, Romero, Laura et al. DOI: 10.1093/cid/ciy1047
PMID: 31433997 Journal: PULMONARY PHARMACOLOGY & THERAPEUTICS Year: 2019 Reference: Pulm Pharmacol Ther. 2019 Oct;58:101834. doi: 10.1016/j.pupt.2019.101834. Epub 2019 Aug 18. Impact factor: 2.669 Publication type: Paper in international publication Authors: Loebinger, Michael R, Polverino, Eva, Blasi, Francesco, Elborn, Stuart J, Chalmers, James D, Tiddens, Harm Awm, Goossens, Herman, Tunney, Michael, Zhou, Wenchun, Angyalosi, Gerhild et al. DOI: 10.1016/j.pupt.2019.101834
PMID: 29880656 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2018 Reference: Eur Respir J. 2018 Aug 16;52(2). pii: 13993003.00537-2018. doi: 10.1183/13993003.00537-2018. Print 2018 Aug. Impact factor: 12.242 Publication type: Letter or abstract Authors: Burman, Matthew, Guglielmetti, Lorenzo, Tiberi, Simon, Kristjansson, Mar, McLaughlin, Anne Marie, Chiappini, Elena, Confalonieri, Marco, Del Bravo, Paola, Gualano, Gina, Motta, Ilaria et al. DOI: 10.1183/13993003.00537-2018
PMID: 30687314 Journal: Frontiers in Immunology Year: 2018 Reference: Front Immunol. 2019 Jan 9;9:3094. doi: 10.3389/fimmu.2018.03094. eCollection 2018. Impact factor: 5.511 Publication type: Paper in international publication Authors: Prat, Cristina, Dominguez, Jose, Sabria, Josefina, Luque-Chacon, Lydia, Lacoma, Alicia, Gonzalez-Diaz, Yoel D, Latorre, Irene, Muriel-Moreno, Beatriz, Villar-Hernandez, Raquel, Vila, Sergi et al. DOI: 10.3389/fimmu.2018.03094
PMID: 29079610 Journal: THORAX Year: 2018 Reference: Thorax. 2018 Aug;73(8):782-784. doi: 10.1136/thoraxjnl-2017-210017. Epub 2017 Oct 27. Impact factor: 9.655 Publication type: Letter or abstract Authors: Vennera, Maria Del Carmen, Sabadell, Carlos, Picado, Cesar, Alvarez Puebla, M J, Irigaray, R, Martinez-Moragon, E, Pellicer, C, Martinez, C, Munoz, X, Canete, C et al. DOI: 10.1136/thoraxjnl-2017-210017
PMID: 28686522 Journal: Archives of Environmental & Occupational Health Year: 2018 Reference: Arch Environ Occup Health. 2018 May 4;73(3):186-188. doi: 10.1080/19338244.2017.1350133. Epub 2017 Jul 31. Impact factor: 1.347 Publication type: Paper in international publication Authors: Cruz, M J, Sampol, J, Pallero, M, Rodriguez, E, Ferrer, J et al. DOI: 10.1080/19338244.2017.1350133
PMID: 29198652 Journal: TRANSPLANTATION PROCEEDINGS Year: 2017 Reference: Transplant Proc. 2017 Dec;49(10):2240-2242. doi: 10.1016/j.transproceed.2017.09.044. Impact factor: 0.908 Publication type: Letter or abstract Authors: Seron, D, Roman, A et al. DOI: 10.1016/j.transproceed.2017.09.044
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PMID: 27132815 Journal: Transplantation Reviews Year: 2016 Reference: Transplant Rev (Orlando). 2016 Jul;30(3):119-43. doi: 10.1016/j.trre.2016.04.001. Epub 2016 Apr 29. Impact factor: 3.915 Publication type: Review in national publication Authors: Aguado, J M, Caston, J J, Almenar, L, Alonso, A, Cantisan, S, Carratala, J, Cervera, C, Cordero, E, Farinas, M C, Fernandez-Ruiz, M et al. DOI: 10.1016/j.trre.2016.04.001
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PMID: 21163212 Journal: NEUROLOGIA Year: 2013 Reference: Neurologia. 2013 Mar;28(2):103-18. doi: 10.1016/j.nrl.2010.09.016. Epub 2010 Nov 19. Impact factor: 1.322 Publication type: Review in national publication Authors: , , , , , , et al. DOI: 10.1016/j.nrl.2010.09.016
PMID: 24236015 Journal: PLoS One Year: 2013 Reference: PLoS One. 2013 Nov 13;8(11):e78304. doi: 10.1371/journal.pone.0078304. Impact factor: 3.73 Publication type: Paper in international publication Authors: Munoz, Xavier, Morell, Ferran, Gomez-Olles, Susana, Cruz, Maria-Jesus, Sanchez-Vidaurre, Sara et al. DOI: 10.1371/journal.pone.0078304
PMID: 23089703 Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE Year: 2012 Reference: Clin Chem Lab Med. 2012 Oct 1;50(10):1749-53. doi: 10.1515/cclm-2012-0042. Impact factor: 2.15 Publication type: Paper in international publication Authors: Camos, Silvia, Cruz, M Jesus, Sole, Esther, Morell, Ferran et al. DOI: 10.1515/cclm-2012-0042
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PMID: 21705277 Journal: CLINICAL IMMUNOLOGY Year: 2011 Reference: Clin Immunol. 2011 Oct;141(1):90-102. Epub 2011 Jun 12. Impact factor: 3.932 Publication type: Paper in international publication Authors: Jolles, S, Bernatowska, E, de Gracia, J, Borte, M, Cristea, V, Peter, H H, Wahn, V, Neufang-Huber, J, Zenker, O, Grimbacher, B et al. DOI: 10.1016/j.clim.2011.06.002
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PhD student: Eva Maria Revilla Lopez, Eva Maria Revilla Lopez Director/s: Susana Gómez Olles, Berta Saez Gimenez University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Irene Belmonte Mula Director/s: Marc Miravitlles Fernández, Francisco Rodríguez Frias University: Universidad Autònoma de Barcelona Year: 2017
PhD student: Daniel Álvarez Simón Director/s: Mª Jesús Cruz Carmona, Fco. Javier Muñoz Gall University: Universidad Autònoma de Barcelona Year: 2017
PhD student: Gerard Muñoz Castro Director/s: Javier de Gracia Roldán University: Universidad Autònoma de Barcelona Year: 2017
PhD student: Maria Antonia Ramon Belmonte, Maria Antonia Ramon Belmonte Director/s: Jaume Ferrer Sancho University: Universidad Autònoma de Barcelona Year: 2015
This recognition highlights both his career and the level of respiratory research in Spain.
The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.
Dr. Miravitlles’ career was recognized during the 57th edition of the SEPAR National Congress held in Valencia.
EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.
EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.
