About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.
The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.
Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.
PMID: 34673289 Journal: Journal of Allergy and Clinical Immunology-In Practice Year: 2022 Reference: J Allergy Clin Immunol Pract. 2022 Mar;10(3):863-866.e1. doi: 10.1016/j.jaip.2021.10.013. Epub 2021 Oct 18. Impact factor: 8.861 Publication type: Paper in international publication Authors: Baptista-Serna, Leyre, Rodrigo-Munoz, Jose Manuel, Minguez, Pablo, Valverde-Monge, Marcela, Arismendi, Ebymar, Barroso, Blanca, Barranco, Pilar, Bobolea, Irina, Canas, Jose Antonio, Cardaba, Blanca et al. DOI: 10.1016/j.jaip.2021.10.013
PMID: 34582842 Journal: CHEST Year: 2022 Reference: Chest. 2022 Mar;161(3):647-650. doi: 10.1016/j.chest.2021.09.016. Epub 2021 Sep 25. Impact factor: 9.41 Publication type: Letter whit IF Authors: Alvarez, Antonio, Andreu, Jordi, Arjona, Marta, Berastegui, Cristina, Barrecheguren, Miriam, Cardoso, Jose, Cruz, Ma Jesus, De Souza, Ma Luiza, Espejo, David, Granados, Galo et al. DOI: 10.1016/j.chest.2021.09.016
PMID: 33875282 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2022 Reference: Arch Bronconeumol. 2022 Jan;58(1):52-68. doi: 10.1016/j.arbres.2021.03.017. Epub 2021 Mar 24. Impact factor: 4.872 Publication type: Paper in national publication Authors: Zabala Urionaguena, Nerea, Mediano, Olga, Gonzalez Mangado, Nicolas, Montserrat, Josep M, Alonso-Alvarez, M Luz, Almendros, Isaac, Alonso-Fernandez, Alberto, Barbe, Ferran, Borsini, Eduardo, Monasterio, Carmen et al. DOI: 10.1016/j.arbres.2021.03.017
PMID: 33849721 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2022 Reference: Arch Bronconeumol. 2022 Jan;58(1):11-21. doi: 10.1016/j.arbres.2021.03.009. Epub 2021 Mar 19. Impact factor: 4.872 Publication type: Paper in national publication Authors: Miravitlles, Marc, Rolon, Annie Navarro, Wang, Xuejie, Tapia, Alicia Marin, Rubio, Myriam Calle, Asensio, Maria Jesus Linares, Orbis, Iria Perez, Olondris, Pilar Martinez, Sanz, Ascension Hernando, Gafas, Alicia de Pablos et al. DOI: 10.1016/j.arbres.2021.03.009
PMID: 33771385 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol (Engl Ed). 2021 Mar 4. pii: S0300-2896(21)00073-9. doi: 10.1016/j.arbres.2021.02.011. Impact factor: 4.872 Publication type: Paper in national publication Authors: Rouzet, Adeline, Morell, Ferran, Reboux, Gabriel, Villar, Ana, Millon, Laurence, Cruz, Maria Jesus et al. DOI: 10.1016/j.arbres.2021.02.011
PMID: 33753747 Journal: npj Primary Care Respiratory Medicine Year: 2021 Reference: NPJ Prim Care Respir Med. 2021 Mar 22;31(1):16. doi: 10.1038/s41533-021-00227-x. Impact factor: 2.871 Publication type: Paper in international publication Authors: Monteagudo, Monica, Barrecheguren, Miriam, Solntseva, Iryna, Dhalwani, Nafeesa, Booth, Alison, Nunez, Alexa, Lambrelli, Dimitra, Miravitlles, Marc et al. DOI: 10.1038/s41533-021-00227-x
PMID: 32253119 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 Mar;57(3):186-194. doi: 10.1016/j.arbres.2020.02.010. Epub 2020 Apr 3. Impact factor: 4.872 Publication type: Paper in national publication Authors: Baz-Redon, Noelia, Fernandez-Cancio, Monica, Moreno-Galdo, Antonio, Camats-Tarruella, Nuria, Tizzano, Eduardo, Amaro-Rodriguez, Rosanel, Rovira-Amigo, Sandra, Paramonov, Ida, Castillo-Corullon, Silvia, Cols Roig, Maria et al. DOI: 10.1016/j.arbres.2020.02.010
PMID: 33004238 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 Mar;57(3):205-213. doi: 10.1016/j.arbres.2020.07.032. Epub 2020 Sep 29. Impact factor: 4.872 Publication type: Paper in national publication Authors: Monteagudo, Monica, Nunez, Alexa, Solntseva, Iryna, Dhalwani, Nafeesa, Booth, Alison, Barrecheguren, Miriam, Lambrelli, Dimitra, Miravitlles, Marc et al. DOI: 10.1016/j.arbres.2020.07.032
PMID: 32279702 Journal: Journal of Clinical Sleep Medicine Year: 2020 Reference: J Clin Sleep Med. 2020 Sep 15;16(9):1579-1589. doi: 10.5664/jcsm.8492. Impact factor: 3.586 Publication type: Paper in international publication Authors: Lloberes, Patricia, Mayos, Merce, Bayo, Joan, Aoiz, Jose Ignacio, Santiveri, Carme, Penacoba, Patricia, Llauger, M Antonia, Fortuna, Ana M, Flor, Xavier, Sampol, Gabriel et al. DOI: 10.5664/jcsm.8492
PMID: 31506210 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Apr;56(4):204-205. doi: 10.1016/j.arbres.2019.07.003. Epub 2019 Sep 7. Impact factor: 4.957 Publication type: Editorial in national publication Authors: Munoz, Xavier, Romero-Mesones, Christian, Cruz, Maria Jesus et al. DOI: 10.1016/j.arbres.2019.07.003
PMID: 31757527 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Apr;56(4):258-259. doi: 10.1016/j.arbres.2019.08.017. Epub 2019 Nov 19. Impact factor: 4.957 Publication type: Paper in national publication Authors: Garmendia, Onintza, Alonso-Alvarez, M feminine Luz, Perez, Noelia, Marti, Sergi, Montserrat, Josep M, Gonzalez, Monica, Farre, Ramon et al. DOI: 10.1016/j.arbres.2019.08.017
PMID: 31506211 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Apr;56(4):254-256. doi: 10.1016/j.arbres.2019.07.013. Epub 2019 Sep 8. Impact factor: 4.957 Publication type: Paper in national publication Authors: Morell, Ferran, Ojanguren, Inigo, Villar, Ana, Ramon, Maria Antonia, Munoz, Xavier, Cruz, Maria Jesus et al. DOI: 10.1016/j.arbres.2019.07.013
PMID: 30616837 Journal: Acta otorrinolaringologica espanola Year: 2019 Reference: Acta Otorrinolaringol Esp. 2019 Nov - Dec;70(6):364-372. doi: 10.1016/j.otorri.2018.06.008. Epub 2019 Jan 5. Impact factor: 0 Publication type: Paper in national publication Authors: Esteller, Eduard, Carrasco, Marina, Diaz-Herrera, Miguel Angel, Sampol, Gabriel, Juvanteny, Joan, Sieira, Ramon, Farre, Alex, Vilaseca, Isabel, Vila, Javier et al. DOI: 10.1016/j.otorri.2018.06.008
PMID: 30604577 Journal: JOURNAL OF SLEEP RESEARCH Year: 2019 Reference: J Sleep Res. 2019 Oct;28(5):e12805. doi: 10.1111/jsr.12805. Epub 2019 Jan 2. Impact factor: 3.432 Publication type: Paper in international publication Authors: Lloberes, Patricia, Campos-Rodriguez, Francisco, Navarro-Soriano, Cristina, Reyes-Nunez, Nuria, Torres, Gerard, Caballero-Eraso, Candela, Masa, Juan F, Gonzalez, Monica, Manas, Eva, de la Pena, Monica et al. DOI: 10.1111/jsr.12805
PMID: 30316648 Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY Year: 2019 Reference: Int J Cardiol. 2019 Jan 15;275:158-164. doi: 10.1016/j.ijcard.2018.10.012. Epub 2018 Oct 5. Impact factor: 3.471 Publication type: Paper in international publication Authors: Del Pozo, Roberto, Blanco, Isabel, Hernandez-Gonzalez, Ignacio, Lopez-Meseguer, Manuel, Lopez-Reyes, Raquel, Lazaro-Salvador, Maria, Elias-Hernandez, Teresa, Alvarez-Vega, Pablo, Perez-Penate, Gregorio Miguel, Martinez-Menaca, Amaya et al. DOI: 10.1016/j.ijcard.2018.10.012
PMID: 30586799 Journal: SCIENCE OF THE TOTAL ENVIRONMENT Year: 2019 Reference: Sci Total Environ. 2019 Feb 20;652:1129-1138. doi: 10.1016/j.scitotenv.2018.10.188. Epub 2018 Oct 15. Impact factor: 5.589 Publication type: Paper in international publication Authors: Munoz, X, Barreiro, E, Bustamante, V, Lopez-Campos, J L, Gonzalez-Barcala, F J, Cruz, M J et al. DOI: 10.1016/j.scitotenv.2018.10.188
PMID: 29531958 Journal: ERJ open research Year: 2018 Reference: ERJ Open Res. 2018 Mar 6;4(1). pii: 00139-2017. doi: 10.1183/23120541.00139-2017. eCollection 2018 Jan. Impact factor: 0 Publication type: Paper in international publication Authors: de la Rosa Carrillo, David, Athanazio, Rodrigo, Giron Moreno, Rosa Maria, Maiz Carro, Luis, Olveira, Casilda, de Gracia, Javier, Vendrell, Montserrat, Prados Sanchez, Concepcion, Gramblicka, Georgina, Corso Pereira, Monica et al. DOI: 10.1183/23120541.00139-2017
PMID: 28631309 Journal: JOURNAL OF SLEEP RESEARCH Year: 2018 Reference: J Sleep Res. 2018 Apr;27(2):232-239. doi: 10.1111/jsr.12571. Epub 2017 Jun 20. Impact factor: 3.433 Publication type: Paper in international publication Authors: Montaner, Joan, Alvarez-Sabin, Jose, Romero, Odile, Delgado, Pilar, Quintana, Manuel, Santamarina, Estevo, Ferre, Alex, Maisterra, Olga, Riba-Llena, Iolanda, Sampol, Gabriel et al. DOI: 10.1111/jsr.12571
PMID: 29505280 Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Year: 2018 Reference: Am J Respir Crit Care Med. 2018 Jun 15;197(12):1648. doi: 10.1164/rccm.201802-0314LE. Impact factor: 15.239 Publication type: Letter or abstract Authors: Vasakova, Martina, Morell, Ferran, Raghu, Ganesh et al. DOI: 10.1164/rccm.201802-0314LE
PMID: 29122336 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2018 Reference: Arch Bronconeumol. 2018 Mar;54(3):121-122. doi: 10.1016/j.arbres.2017.08.008. Epub 2017 Nov 6. Impact factor: 2.633 Publication type: Paper in national publication Authors: Cruz, Maria Jesus, Romero-Mesones, Christian, Munoz, Xavier et al. DOI: 10.1016/j.arbres.2017.08.008
PMID: 28301586 Journal: PLoS One Year: 2017 Reference: PLoS One. 2017 Mar 16;12(3):e0174092. doi: 10.1371/journal.pone.0174092. eCollection 2017. Impact factor: 2.806 Publication type: Paper in international publication Authors: Sole, Joan, Canela, Merce, Gamez, Josep, Salvado, Maria, Deu, Maria, Romero, Laura, Roman, Antonio, Sacanell, Judith, Laborda, Cesar, Rochera, Isabel et al. DOI: 10.1371/journal.pone.0174092
PMID: 28294487 Journal: Transplant Infectious Disease Year: 2017 Reference: Transpl Infect Dis. 2017 Jun;19(3). doi: 10.1111/tid.12694. Epub 2017 May 9. Impact factor: 1.719 Publication type: Paper in international publication Authors: Cifrian, J M, Pastor, A, Roman, Antonio, Ussetti, Piedad, Redel-Montero, Javier, Borro, J M, Sole, A, Monforte, Victor, Sintes, Helena, Lopez-Gallo, C et al. DOI: 10.1111/tid.12694
PMID: 28270447 Journal: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Year: 2017 Reference: Occup Environ Med. 2017 Aug;74(8):586-591. doi: 10.1136/oemed-2016-103806. Epub 2017 Mar 7. Impact factor: 3.912 Publication type: Paper in international publication Authors: Hu, Chunshao, Cruz, Maria-Jesus, Ojanguren, Inigo, de Homdedeu, Miquel, Gonzalez-Barcala, Francisco-Javier, Munoz, Xavier et al. DOI: 10.1136/oemed-2016-103806
PMID: 28245723 Journal: ACTA CLINICA BELGICA Year: 2017 Reference: Acta Clin Belg. 2017 Dec;72(6):379-384. doi: 10.1080/17843286.2017.1295524. Epub 2017 Mar 1. Impact factor: 0.622 Publication type: Paper in international publication Authors: Gonzalez-Barcala, Francisco-Javier, Calvo-Alvarez, Uxio, Salgado-Castro, Francisco-Javier, Facal, David, Garcia-Sanz, Maria-Teresa, Munoz, Xavier, Garcia-Couceiro, Nuria, Paz-Neira, Olalla, San-Jose, Esther, Valdes-Cuadrado, Luis et al. DOI: 10.1080/17843286.2017.1295524
PMID: 24638776 Journal: CHEST Year: 2014 Reference: Chest. 2014 Mar 1;145(3 Suppl):631A. doi: 10.1378/chest.1799525. Impact factor: 7.132 Publication type: Paper in international publication Authors: Riera, Jordi, Caralt, Berta, Augustin, Salvador, Masclans, Joan Ramon, Canela, Merce, Roman, Antonio, Rello, Jordi et al. DOI: 10.1378/chest.1799525
PMID: 24582312 Journal: J ALLERGY CLIN IMMUN Year: 2014 Reference: J Allergy Clin Immunol. 2014 Jul;134(1):116-26. doi: 10.1016/j.jaci.2013.12.1077. Epub 2014 Feb 28. Impact factor: 11.248 Publication type: Paper in international publication Authors: Thon, Vojtech, Borte, Michael, Borte, Stephan, Kumararatne, Dinakantha, Feighery, Conleth, Longhurst, Hilary, Helbert, Matthew, Szaflarska, Anna, Sediva, Anna, Belohradsky, Bernd H et al. DOI: 10.1016/j.jaci.2013.12.1077
PMID: 24603815 Journal: EUR RESPIR J Year: 2014 Reference: Eur Respir J. 2014 Jun;43(6):1573-87. doi: 10.1183/09031936.00180313. Epub 2014 Mar 6. Impact factor: 7.125 Publication type: Paper in international publication Authors: Cullinan, Paul, Walusiak-Skorupa, Jolanta, Suuronen, Katri, Sigsgaard, Torben, Sastre, Joaquin, Suojalehto, Hille, Aasen, Tor B, Baur, Xaver, Burge, P Sherwood, de Blay, Frederic et al. DOI: 10.1183/09031936.00180313
PMID: 24533134 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Feb 12;9(2):e88676. doi: 10.1371/journal.pone.0088676. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Morell, Ferran, Gomez-Olles, Susana, Villalbi, Joan R, Munoz, Xavier, Cruz, Maria-Jesus, Alvarez-Simon, Daniel, Untoria, Maria-Dolores et al. DOI: 10.1371/journal.pone.0088676
PMID: 22440140 Journal: MEDICINA CLINICA Year: 2013 Reference: Med Clin (Barc). 2013 Feb 16;140(4):152-6. doi: 10.1016/j.medcli.2012.01.023. Epub 2012 Mar 21. Impact factor: 1.399 Publication type: Paper in national publication Authors: , , , , , et al. DOI: 10.1016/j.medcli.2012.01.023
Vall d'Hebron participated in the study in which more than half of the patients who received treatment with bacteriophages experienced significant improvements
La recerca és fonamental per contrarestar els efectes de la pol·lució, que segons l’AEMPS, va ser la causa de més de 300.000 morts prematures a la UE el 2020.
Pulmonary hypertension is a risk factor for patients who need surgery and, therefore, defining strategies for its management is important to allow a favorable clinical evolution.
EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.
EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.
