About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.
The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.
Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.
PMID: 38026127 Journal: Year: 2023 Reference: Front Allergy. 2023 Nov 9;4:1296894. doi: 10.3389/falgy.2023.1296894. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Aceituno-Lopez, Maria Angeles; Alobid, Isam; Camprodon-Gomez, Maria; Del-Toro-Riera, Mireia; Espinosa, Miriam; Gomez de la Fuente, Enrique; Lara-Fernandez, Roser; Luca de Tena, Africa; Marti-Beltran, Sergi; Moreno-Galdo, Antonio et al. DOI: 10.3389/falgy.2023.1296894
PMID: 38033506 Journal: EClinicalMedicine Year: 2023 Reference: EClinicalMedicine. 2023 Nov 15;65:102307. doi: 10.1016/j.eclinm.2023.102307. eCollection 2023 Nov. Impact factor: Publication type: Paper in international publication Authors: Abdelrahman Soliman, Dina Sameh; Al-Shemari, Salem; Alcoceba, Miguel; Alobid, Isam; Angelopoulou, Maria; Antic, Darko; Aurran-Schleinitz, Therese; Bacchiarri, Francesca; Bellido, Mar; Biderman, Bella et al. DOI: 10.1016/j.eclinm.2023.102307
PMID: 38056890 Journal: European Respiratory Review Year: 2023 Reference: Eur Respir Rev. 2023 Dec 6;32(170):230170. doi: 10.1183/16000617.0170-2023. Print 2023 Dec 31. Impact factor: Publication type: Paper in international publication Authors: Anzueto, Antonio; Barrecheguren, Miriam; Miravitlles, Marc et al. DOI: 10.1183/16000617.0170-2023
PMID: 35312607 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2022 Reference: Arch Bronconeumol. 2022 Mar;58(3):228-236. doi: 10.1016/j.arbres.2021.05.019. Epub 2021 Jun 4. Impact factor: 4.872 Publication type: Paper in national publication Authors: Benitez, Ivan D, Sanchez-Quiroga, Maria A, Gomez de Terreros, Francisco J, Corral, Jaime, Romero, Auxiliadora, Caballero-Eraso, Candela, Ordax-Carbajo, Estrella, Troncoso, Maria F, Gonzalez, Monica, Lopez-Martin, Soledad et al. DOI: 10.1016/j.arbres.2021.05.019
PMID: 34331263 Journal: INFECTION Year: 2022 Reference: Infection. 2022 Apr;50(2):371-380. doi: 10.1007/s15010-021-01662-1. Epub 2021 Jul 30. Impact factor: 3.553 Publication type: Paper in international publication Authors: Kirkegaard, Cristina, Falco-Roget, Anna, Sanchez-Montalva, Adrian, Valls, Angel, Clofent, David, Campos-Varela, Isabel, Garcia-Garcia, Sonia, Leguizamo, Lina Maria, Sellares-Nadal, Julia, Eremiev, Simeon et al. DOI: 10.1007/s15010-021-01662-1
PMID: 35312537 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2022 Reference: Arch Bronconeumol. 2022 Jan 12. pii: S0300-2896(22)00013-8. doi: 10.1016/j.arbres.2021.12.015. Impact factor: 4.872 Publication type: Paper in national publication Authors: Gonzalez, Jessica, Carmona, Paola, Gracia-Lavedan, Esther, Benitez, Ivan D, Anton, Antonio, Balana, Anna, Diaz, Sonia Belda, Bernadich, Oscar, Cordoba, Ana, Embid, Cristina et al. DOI: 10.1016/j.arbres.2021.12.015
PMID: 35273167 Journal: npj Primary Care Respiratory Medicine Year: 2022 Reference: NPJ Prim Care Respir Med. 2022 Mar 10;32(1):11. doi: 10.1038/s41533-022-00270-2. Impact factor: 2.871 Publication type: Paper in international publication Authors: Barrecheguren, Miriam, Monteagudo, Monica, Miravitlles, Marc, Flor, Xavier, Nunez, Alexa, Osorio, Jeisson, Munoz, Xavier, Ojanguren, Inigo et al. DOI: 10.1038/s41533-022-00270-2
PMID: 32654945 Journal: REVISTA ESPANOLA DE CARDIOLOGIA Year: 2021 Reference: Rev Esp Cardiol (Engl Ed). 2021 May;74(5):384-392. doi: 10.1016/j.rec.2020.06.006. Epub 2020 Jul 9. Impact factor: 4.753 Publication type: Paper in national publication Authors: Martinez-Santos, Paula, Velazquez-Martin, Maria Teresa, Barbera, Joan Albert, Fernandez Perez, Cristina, Lopez-Meseguer, Manuel, Martinez-Menaca, Amaya, Lara-Padron, Antonio, Domingo-Morera, Juan Antonio, Blanco, Isabel, Escribano-Subias, Pilar et al. DOI: 10.1016/j.rec.2020.06.006
PMID: 33900052 Journal: Clinical and Translational Allergy Year: 2021 Reference: Clin Transl Allergy. 2021 Mar;11(1):e12001. doi: 10.1002/clt2.12001. Impact factor: 5.871 Publication type: Paper in international publication Authors: Sastre, Joaquin, Pozo, Victora Del, Valverde, Marcela, Valero, Antonio, Sastre, Beatriz, Rial, Manuel J, Alvarez-Puebla, Maria J, Arismendi, Ebymar, Caballero, Maria L, Canas, Jose A et al. DOI: 10.1002/clt2.12001
PMID: 32616302 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 May;57(5):317-318. doi: 10.1016/j.arbres.2020.05.031. Epub 2020 Jun 29. Impact factor: 4.872 Publication type: Editorial in national publication Authors: Clofent, David, Culebras, Mario, Loor, Karina, Cruz, M Jesus et al. DOI: 10.1016/j.arbres.2020.05.031
PMID: 33859049 Journal: THORAX Year: 2021 Reference: Thorax. 2021 Nov;76(11):1108-1116. doi: 10.1136/thoraxjnl-2020-215613. Epub 2021 Apr 15. Impact factor: 9.25 Publication type: Review in international publication Authors: Lebret, Marius, Leotard, Antoine, Pepin, Jean Louis, Windisch, Wolfram, Ekkernkamp, Emelie, Pallero, Mercedes, Sanchez-Quiroga, M-Angeles, Hart, Nicholas, Kelly, Julia L, Patout, Maxime et al. DOI: 10.1136/thoraxjnl-2020-215613
PMID: 31387460 Journal: PERFUSION-UK Year: 2020 Reference: Perfusion. 2020 Apr;35(3):267-270. doi: 10.1177/0267659119864813. Epub 2019 Aug 7. Impact factor: 1.234 Publication type: Paper in international publication Authors: Argudo, Eduard, Riera, Jordi, Luque, Sonia, Los-Arcos, Ibai, Lopez-Meseguer, Manuel, Sandiumenge, Alberto, Nuvials, Xavier, Grau, Santiago, Ferrer, Ricard et al. DOI: 10.1177/0267659119864813
PMID: 31128847 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Apr;56(4):252. doi: 10.1016/j.arbres.2019.03.030. Epub 2019 May 23. Impact factor: 4.957 Publication type: Paper in national publication Authors: Felipe Montiel, Almudena, Loor Reyes, Karina, Culebras Amigo, Mario et al. DOI: 10.1016/j.arbres.2019.03.030
PMID: 31128848 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2020 Reference: Arch Bronconeumol. 2020 Mar;56(3):139-140. doi: 10.1016/j.arbres.2019.04.008. Epub 2019 May 22. Impact factor: 4.957 Publication type: Editorial in national publication Authors: de Souza-Galvao, Maria Luiza, Jimenez-Fuentes, Maria Angeles et al. DOI: 10.1016/j.arbres.2019.04.008
PMID: 32280207 Journal: International Journal of Chronic Obstructive Pulmonary Disease Year: 2020 Reference: Int J Chron Obstruct Pulmon Dis. 2020 Mar 31;15:681-690. doi: 10.2147/COPD.S240720. eCollection 2020. Impact factor: 2.772 Publication type: Paper in international publication Authors: Nunez, Alexa, Marras, Viviana, Harlander, Matevz, Mekov, Evgeni, Esquinas, Cristina, Turel, Matjaz, Lestan, David, Petkov, Rosen, Yanev, Nikolay, Pirina, Pietro et al. DOI: 10.2147/COPD.S240720
PMID: 30676482 Journal: JOURNAL OF HYPERTENSION Year: 2019 Reference: J Hypertens. 2019 Jun;37(6):1269-1275. doi: 10.1097/HJH.0000000000002053. Impact factor: 4.209 Publication type: Paper in international publication Authors: Navarro-Soriano, Cristina, Martinez-Garcia, Miguel-Angel, Torres, Gerard, Barbe, Ferran, Caballero-Eraso, Candela, Lloberes, Patricia, Diaz Cambriles, Trinidad, Somoza, Maria, Masa, Juan F, Gonzalez, Monica et al. DOI: 10.1097/HJH.0000000000002053
PMID: 30621833 Journal: Journal of Clinical Sleep Medicine Year: 2019 Reference: J Clin Sleep Med. 2019 Jan 15;15(1):89-99. doi: 10.5664/jcsm.7578. Impact factor: 3.456 Publication type: Paper in international publication Authors: Ferre, Alex, Poca, Maria A, de la Calzada, Maria Dolore, Moncho, Dulce, Urbizu, Aintzane, Romero, Odile, Sampol, Gabriel, Sahuquillo, Juan et al. DOI: 10.5664/jcsm.7578
PMID: 30649011 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2019 Reference: Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):105-110. doi: 10.1097/ACI.0000000000000511. Impact factor: 3.014 Publication type: Paper in international publication Authors: Cruz, Maria-Jesus, Morell, Ferran, Ojanguren, Inigo et al. DOI: 10.1097/ACI.0000000000000511
PMID: 30641195 Journal: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY Year: 2019 Reference: Ann Allergy Asthma Immunol. 2019 Apr;122(4):424-425.e1. doi: 10.1016/j.anai.2019.01.007. Epub 2019 Jan 12. Impact factor: 3.56 Publication type: Paper in international publication Authors: Solana, E, Cruz, M J, Romero-Mesones, C, Munoz, X et al. DOI: 10.1016/j.anai.2019.01.007
PMID: 29566971 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2018 Reference: Archivos de Bronconeumología. 2018 Jul;54(7):378-85. doi: 10.1016/j.arbres.2017.12.012. Impact factor: 2.633 Publication type: Paper in national publication Authors: Quirce, Santiago, Ramos, David, Rial, Manuel, Romero-Mesones, Christian, Salgado, Francisco Javier, San-Jose, Maria Esther, Sanchez-Diez, Silvia, Sastre, Beatriz, Sastre, Joaquin, Soto, Lorena et al. DOI: 10.1016/j.arbres.2017.12.012
PMID: 29548801 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2018 Reference: Arch Bronconeumol. 2018 Sep;54(9):484-486. doi: 10.1016/j.arbres.2018.01.015. Epub 2018 Mar 13. Impact factor: 2.633 Publication type: Paper in national publication Authors: Jimenez-Fuentes, Maria Angeles, Mila Auge, Celia, Solsona Peiro, Jordi, de Souza-Galvao, Maria Luiza et al. DOI: 10.1016/j.arbres.2018.01.015
PMID: 29555449 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2018 Reference: Arch Bronconeumol. 2018 Sep;54(9):445-446. doi: 10.1016/j.arbres.2018.02.005. Epub 2018 Mar 16. Impact factor: 2.633 Publication type: Editorial in national publication Authors: Morell, Ferran, Ojanguren, Inigo, Cruz, Maria Jesus et al. DOI: 10.1016/j.arbres.2018.02.005
PMID: 29534846 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2018 Reference: Arch Bronconeumol. 2018 Jun;54(6):313-319. doi: 10.1016/j.arbres.2018.01.013. Epub 2018 Mar 10. Impact factor: 2.633 Publication type: Paper in national publication Authors: Jauregui, Alberto, Deu, Maria, Romero, Laura, Roman, Antonio, Moreno, Antonio, Armengol, Manuel, Sole, Juan et al. DOI: 10.1016/j.arbres.2018.01.013
PMID: 28453783 Journal: SLEEP Year: 2017 Reference: Sleep. 2017 Jun 1;40(6). pii: 3766874. doi: 10.1093/sleep/zsx069. Impact factor: 4.923 Publication type: Paper in international publication Authors: Ferre, Alex, Poca, Maria A, de la Calzada, Maria D, Moncho, Dulce, Romero, Odile, Sampol, Gabriel, Sahuquillo, Juan et al. DOI: 10.1093/sleep/zsx069
PMID: 28449046 Journal: Interactive cardiovascular and thoracic surgery Year: 2017 Reference: Interact Cardiovasc Thorac Surg. 2017 Aug 1;25(2):292-296. doi: 10.1093/icvts/ivx073. Impact factor: 0 Publication type: Paper in international publication Authors: Baldira, Jaume, Lagunes, Leonel, Augustin, Salvador, Roman, Antonio, Due, Maria, Rello, Jordi, Levine, Deborah J, Martinez, Maria, Mazo, Cristopher, Maldonado, Carolina et al. DOI: 10.1093/icvts/ivx073
PMID: 28439933 Journal: ALLERGY Year: 2017 Reference: Allergy. 2017 Nov;72(11):1720-1727. doi: 10.1111/all.13190. Epub 2017 Jul 20. Impact factor: 7.361 Publication type: Paper in international publication Authors: Vanoirbeek, J, Olle-Monge, M, Cruz, M J, Gomez-Olles, S, Ojanguren, I, Munoz, X et al. DOI: 10.1111/all.13190
PMID: 28393532 Journal: Chronic Respiratory Disease Year: 2017 Reference: Chron Respir Dis. 2017 Nov;14(4):360-369. doi: 10.1177/1479972317702139. Epub 2017 Apr 10. Impact factor: 1.818 Publication type: Paper in international publication Authors: Rajas, Olga, Soriano, Joan B, Martinez-Moragon, Eva, Polverino, Eva, Borderias, Luis, Vazquez, Liliana, Giron, Rosa Ma, de Gracia Roldan, Javier, Olveira, Casilda, Vendrell, Montserrat et al. DOI: 10.1177/1479972317702139
PMID: 24708188 Journal: CLIN TRANSPLANT Year: 2014 Reference: Clin Transplant. 2014 Jun;28(6):743-8. doi: 10.1111/ctr.12371. Epub 2014 May 14. Impact factor: 1.486 Publication type: Paper in international publication Authors: Pou, Leonor, Roman, Antonio, Bravo, Carlos, Lopez-Meseguer, Manuel, Berastegui, Cristina, Monforte, Victor, Mendez, Alejandra et al. DOI: 10.1111/ctr.12371
PMID: 23932566 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Apr 22;142(8):348-54. doi: 10.1016/j.medcli.2013.01.051. Epub 2013 Aug 7. Impact factor: 1.252 Publication type: Paper in national publication Authors: Morell, Ferran, Ojanguren, Inigo, Cordovilla, Rosa, Urrutia, Isabel, Aguero, Ramon, Guerra, Javier, Genover, Teresa, Ramon, Maria Antonia et al. DOI: 10.1016/j.medcli.2013.01.051
PMID: 24638776 Journal: CHEST Year: 2014 Reference: Chest. 2014 Mar 1;145(3 Suppl):631A. doi: 10.1378/chest.1799525. Impact factor: 7.132 Publication type: Paper in international publication Authors: Riera, Jordi, Caralt, Berta, Augustin, Salvador, Masclans, Joan Ramon, Canela, Merce, Roman, Antonio, Rello, Jordi et al. DOI: 10.1378/chest.1799525
PMID: 24638713 Journal: CHEST Year: 2014 Reference: Chest. 2014 Mar 1;145(3 Suppl):563A. doi: 10.1378/chest.1823743. Impact factor: 7.132 Publication type: Paper in international publication Authors: Acuna, Mauricio, Riera, Jordi, Rello, Jordi, Roman, Antonio et al. DOI: 10.1378/chest.1823743
PMID: 23332731 Journal: JOURNAL OF HEART AND LUNG TRANSPLANTATION Year: 2013 Reference: J Heart Lung Transplant. 2013 Mar;32(3):313-9. doi: 10.1016/j.healun.2012.11.013. Epub 2013 Jan 16. Impact factor: 5.112 Publication type: Paper in international publication Authors: Sole, Amparo, Monforte, Victor, Lopez-Sanchez, Almudena, Zurbano, Felipe, Ussetti, Piedad, de Pablos, Alicia, Bravo, Carles, Roman, Antonio, Cifrian, Jose, Casals, Cristina et al. DOI: 10.1016/j.healun.2012.11.013
PMID: 22458533 Journal: Influenza and Other Respiratory Viruses Year: 2013 Reference: Influenza Other Respir Viruses. 2013 Mar;7(2):177-83. doi: 10.1111/j.1750-2659.2012.00361.x. Epub 2012 Mar 27. Impact factor: 1.471 Publication type: Paper in international publication Authors: , , , , , , , Bravo Masgoret, Carles, , et al. DOI: 10.1111/j.1750-2659.2012.00361.x
PMID: 22939738 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2013 Reference: Arch Bronconeumol. 2013 Feb;49(2):70-8. doi: 10.1016/j.arbres.2012.06.001. Epub 2012 Aug 28. Impact factor: 1.372 Publication type: Paper in national publication Authors: Salvatierra, Angel, Coll, Elisabeth, Santos, Francisco, Ussetti, Pietat, Canela, Mercedes, Borro, Jose Maria, De La Torre, Mercedes, Varela, Andres, Zurbano, Felipe, Mons, Roberto et al. DOI: 10.1016/j.arbres.2012.06.001
PMID: 23276646 Journal: Transplantation Reviews Year: 2013 Reference: Transplant Rev (Orlando). 2013 Jan;27(1):9-16. doi: 10.1016/j.trre.2012.11.001. Epub 2012 Dec 28. Impact factor: 2.675 Publication type: Review in international publication Authors: Laporta, R, Monforte, V, Roman, A, la Torre, M de, Ussetti, P, Zurbano, F, Cifrian, J M, Borro, J M, Santos, F, de Pablo, A et al. DOI: 10.1016/j.trre.2012.11.001
Vall d'Hebron participated in the study in which more than half of the patients who received treatment with bacteriophages experienced significant improvements
La recerca és fonamental per contrarestar els efectes de la pol·lució, que segons l’AEMPS, va ser la causa de més de 300.000 morts prematures a la UE el 2020.
Pulmonary hypertension is a risk factor for patients who need surgery and, therefore, defining strategies for its management is important to allow a favorable clinical evolution.
EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.
EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.
