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Psychiatry, Mental Health and Addictions

The Psychiatry, Mental Health and Addictions Research Group at the Vall d'Hebron Research Institute is a multidisciplinary team that over the past 13 years has focused its scientific activity on the research (both nationally and internationally) of clinical, therapeutic and etiopathogenic aspects of:

  • Neurodevelopmental Disorders (especially Attention-Deficit / Hyperactivity Disorder, Autism and Fetal Alcohol Syndrome).
  • Personality Disorders (especially Borderline Personality Disorder).
  • Addictive behaviours (especially Dual Pathology and Smoking).
  • Transcultural Psychiatry.
  • Interconsultation and Liaison Psychiatry.
  • Resistant Major Depressive Disorder.
  • Perinatal psychiatry.
  • Child sexual abuse and maltreatment.

At international level, it participates and/or coordinates several European projects of great repercussion in the area of mental health. At national level, it is part of the CIBERSAM (Centre for Biomedical Research in Mental Health Network) together with other leading groups, conducting research of excellence.

Team

Oscar Soto Angona

Oscar Soto Angona

Predoctoral researcher
Psychiatry, Mental Health and Addictions
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Raquel Vidal Estrada

Raquel Vidal Estrada

Senior researcher
Psychiatry, Mental Health and Addictions
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Andrea Salvat San Agustin

Andrea Salvat San Agustin

Predoctoral researcher
Psychiatry, Mental Health and Addictions
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Gemma Nieva Rifa

Gemma Nieva Rifa

Research technician
Psychiatry, Mental Health and Addictions
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Julia Vendrell Serres

Julia Vendrell Serres

Research assistant
Psychiatry, Mental Health and Addictions
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Maria Pilar Meler Amella

Maria Pilar Meler Amella

Research technician
Psychiatry, Mental Health and Addictions
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Oscar Soto Angona

Oscar Soto Angona

Predoctoral researcher
Psychiatry, Mental Health and Addictions
Read more
Raquel Vidal Estrada

Raquel Vidal Estrada

Senior researcher
Psychiatry, Mental Health and Addictions
Read more
Andrea Salvat San Agustin

Andrea Salvat San Agustin

Predoctoral researcher
Psychiatry, Mental Health and Addictions
Read more
Gemma Nieva Rifa

Gemma Nieva Rifa

Research technician
Psychiatry, Mental Health and Addictions
Read more
Julia Vendrell Serres

Julia Vendrell Serres

Research assistant
Psychiatry, Mental Health and Addictions
Read more
Maria Pilar Meler Amella

Maria Pilar Meler Amella

Research technician
Psychiatry, Mental Health and Addictions
Read more

Projects

Desarrollo de programas telemáticos de intervención psicológica para el tratamiento de los trastornos funcionales digestivos.l

IP: Jorge Serra Pueyo
Collaborators: Ariadna Aguilar Cayuelas, Anna Beneria González, Claudia Barber Caselles
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI22/00618
Duration: 01/01/2023 - 31/12/2025

ESTUDIO DE SEGUIMIENTO DEL TRASTORNO LIMITE DE PERSONALIDAD: REEVALUACION CLINICA Y DE NEUROIMAGEN A LOS 6 AÑOS DEL DIAGNÓSTICO EN LA ADOLESCENCIA

IP: Marc Ferrer Vinardell
Collaborators: Natalia Calvo Piñero, Gemma Nieva Rifa, Gemma Español Martín, Alexandre Rue Jimenez, Mar Baz Montero, Gara Arteaga Henriquez
Funding agency: Instituto de Salud Carlos III
Funding: 62920
Reference: PI22/01131
Duration: 01/01/2023 - 31/12/2025

Modelos predictivos basados en datos genéticos, transcriptómicos y de micro ARN para el estudio del TDAH: un enfoque multiómico.

IP: Maria Soler Artigas
Collaborators: Montserrat Corrales De la Cruz, José Antonio Ramos Quiroga, Christian Fadeuilhe Grau, Natalia Llonga Tejedor
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI22/00464
Duration: 01/01/2023 - 31/12/2025

Beques Sara Borrell

IP: Marta Ribases Haro
Collaborators: Silvia Amoretti Guadall
Funding agency: Instituto de Salud Carlos III
Funding: 80598
Reference: CD20/00177
Duration: 11/01/2021 - 10/01/2024

Publications

Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia: Post-hoc analysis of StopPRE trial.

PMID: 37555464
Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Year: 2023
Reference: BJOG. 2023 Aug 9. doi: 10.1111/1471-0528.17631.
Impact factor:
Publication type: Paper in international publication
Authors: Alsius, Merce; Bonacina, Erika; Caamina, Sara; Carreras, Elena; Castillo-Ribelles, Laura; de Mingo, Laura; Diaz, Sonia; Garcia, Esperanza; Garcia-Manau, Pablo; Lopez, Monica et al.
DOI: 10.1111/1471-0528.17631

Identifying risk factors for predominant negative symptoms from early stages in schizophrenia: A longitudinal and sex-specific study in first-episode schizophrenia patients.

PMID: 37716849
Journal: Revista de Psiquiatria y Salud Mental
Year: 2023
Reference: Rev Psiquiatr Salud Ment. 2023 Feb 1:S1888-9891(23)00005-8. doi: 10.1016/j.rpsm.2023.01.004.
Impact factor:
Publication type: Paper in national publication
Authors: Amoretti, Silvia; Bernardo, Miguel; Berrocoso, Esther; Bioque, Miquel; Corripio, Iluminada; Cuesta, Manuel J; Garcia-Portilla, Maria Paz; Garcia-Rizo, Clemente; Gonzalez-Pinto, Ana; Ibanez, Angela et al.
DOI: 10.1016/j.rpsm.2023.01.004

Attention-deficit/hyperactivity disorder is associated with increased risk of cardiovascular diseases: A systematic review and meta-analysis.

PMID: 37720588
Journal: JCPP advances
Year: 2023
Reference: JCPP Adv. 2023 Apr 5;3(3):e12158. doi: 10.1002/jcv2.12158. eCollection 2023 Sep.
Impact factor:
Publication type: Paper in international publication
Authors: Brikell, Isabell; Chang, Zheng; Cortese, Samuele; Du Rietz, Ebba; Garcia-Argibay, Miguel; Larsson, Henrik; Li, Lin; Ramos-Quiroga, J Antoni; Ramos-Quiroga, J Antoni; Ribases, Marta et al.
DOI: 10.1002/jcv2.12158

Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals.

PMID: 37731936
Journal: EClinicalMedicine
Year: 2023
Reference: EClinicalMedicine. 2023 Sep 8;64:102199. doi: 10.1016/j.eclinm.2023.102199. eCollection 2023 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Addington, Jean Margaret; Amoretti, Silvia; Andreassen, Ole Andreas; Argote, Mathilde; Asmal, Laila; Baudin, Gregoire; Bechdolf, Andreas; Brambilla, Paolo; Brunelin, Jerome; Cookey, Jacob et al.
DOI: 10.1016/j.eclinm.2023.102199

Cariprazine Use in Combination With a Mood Stabilizer in First Episode Mania.

PMID: 35633804
Journal: Frontiers in Psychiatry
Year: 2022
Reference: Front Psychiatry. 2022 May 11;13:828088. doi: 10.3389/fpsyt.2022.828088. eCollection 2022.
Impact factor: 4.157
Publication type: Paper in international publication
Authors: Palacios-Garran, Roberto, Del Agua, Enrique, Arteaga-Henriquez, Gara, Llorca-Bofi, Vicent et al.
DOI: 10.3389/fpsyt.2022.828088

Shaped before birth: Obstetric complications identify a more severe clinical phenotype among patients presenting a first affective or non-affective episode of psychosis.

PMID: 35609362
Journal: JOURNAL OF PSYCHIATRIC RESEARCH
Year: 2022
Reference: J Psychiatr Res. 2022 Jul;151:461-468. doi: 10.1016/j.jpsychires.2022.05.005. Epub 2022 May 17.
Impact factor: 4.791
Publication type: Paper in international publication
Authors: Sague-Vilavella, Maria, Vieta, Eduard, Verdolini, Norma, Garcia-Rizo, Clemente, Bernardo, Miguel, Pacchiarotti, Isabella, Mezquida, Gisela, Williams, Evelyn, Serra-Navarro, Maria, Forte, Maria Florencia et al.
DOI: 10.1016/j.jpsychires.2022.05.005

Emotional intelligence: a comparison between patients after first episode mania and those suffering from chronic bipolar disorder type I.

PMID: 35574736
Journal: PSYCHOLOGICAL MEDICINE
Year: 2022
Reference: Psychol Med. 2022 Jan 7:1-12. doi: 10.1017/S0033291721005122.
Impact factor: 7.723
Publication type: Paper in international publication
Authors: Salagre, Estela, Benabarre, Antoni, Salgado-Pineda, Pilar, Montoro Salvatierra, Irene, Saiz, Pilar A, Garcia-Portilla, Maria Paz, Sanchez-Gistau, Vanessa, Pomarol-Clotet, Edith, Ramos-Quiroga, Josep Antoni, Pacchiarotti, Isabella et al.
DOI: 10.1017/S0033291721005122

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials.

PMID: 34907394
Journal: MOLECULAR PSYCHIATRY
Year: 2022
Reference: Mol Psychiatry. 2022 Mar;27(3):1286-1299. doi: 10.1038/s41380-021-01381-x. Epub 2021 Dec 15.
Impact factor: 15.992
Publication type: Review in international publication
Authors: Schatzberg, Alan F, Bauer, Michael, Baune, Bernhard T, Blier, Pierre, Cleare, Anthony J, Cowen, Philip J, Dinan, Timothy G, Fagiolini, Andrea, Ferrier, I Nicol, Hegerl, Ulrich et al.
DOI: 10.1038/s41380-021-01381-x

Functioning assessment short test (FAST): validity and reliability in adults with Autism Spectrum Disorder.

PMID: 34187406
Journal: BMC Psychiatry
Year: 2021
Reference: BMC Psychiatry. 2021 Jun 29;21(1):321. doi: 10.1186/s12888-021-03330-y.
Impact factor: 3.63
Publication type: Paper in international publication
Authors: Bonnin, C Mar, Quiroga, Josep Antoni Ramos, Vieta, Eduard, Martin, Gemma Espanol, Lugo-Marin, Jorge, Gisbert-Gustemps, Laura, Ramos, Imanol Setien et al.
DOI: 10.1186/s12888-021-03330-y

Insomnia Disorder in Adult Attention-Deficit/Hyperactivity Disorder Patients: Clinical, Comorbidity, and Treatment Correlates.

PMID: 34122179
Journal: Frontiers in Psychiatry
Year: 2021
Reference: Front Psychiatry. 2021 May 26;12:663889. doi: 10.3389/fpsyt.2021.663889. eCollection 2021.
Impact factor: 4.157
Publication type: Paper in international publication
Authors: Palma-Alvarez, Raul F, Fadeuilhe, Christian, Daigre, Constanza, Richarte, Vanesa, Grau-Lopez, Lara, Ramos-Quiroga, Josep A, Corrales, Montse et al.
DOI: 10.3389/fpsyt.2021.663889

Strengths and Difficulties Questionnaire: Psychometric Properties and Normative Data for Spanish 5- to 17-Year-Olds.

PMID: 32449368
Journal: ASSESSMENT
Year: 2021
Reference: Assessment. 2021 Jul;28(5):1445-1458. doi: 10.1177/1073191120918929. Epub 2020 May 25.
Impact factor: 4.667
Publication type: Paper in international publication
Authors: Espanol-Martin, Gemma, Pagerols, Mireia, Prat, Raquel, Rivas, Cristina, Sixto, Laura, Valero, Sergi, Artigas, Maria Soler, Ribases, Marta, Ramos-Quiroga, Josep A, Casas, Miquel et al.
DOI: 10.1177/1073191120918929

End of Life Intervention Program During COVID-19 in Vall d'Hebron University Hospital.

PMID: 34040548
Journal: Frontiers in Psychiatry
Year: 2021
Reference: Front Psychiatry. 2021 May 3;12:608973. doi: 10.3389/fpsyt.2021.608973. eCollection 2021.
Impact factor: 4.157
Publication type: Paper in international publication
Authors: Montes, Maria Jose, Rios, Giuliana, Bosch, Rosa, Citoler, Barbara, Closa, Helena, Corrales, Montserrat, Daigre, Constanza, Delgado, Mercedes, Dip, Maria Emilia, Estelrich, Neus et al.
DOI: 10.3389/fpsyt.2021.608973

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.

PMID: 31506971
Journal: ALLERGY
Year: 2020
Reference: Allergy. 2020 Feb;75(2):370-380. doi: 10.1111/all.14016. Epub 2019 Sep 10.
Impact factor: 8.706
Publication type: Paper in international publication
Authors: Chung, Kian Fan, Barta, Imre, Hohlfeld, Jens, Greulich, Timm, van den Berge, Maarten, Hiemstra, Pieter S, Timens, Wim, Hinks, Timothy, Wenzel, Sally, Siddiqui, Salman et al.
DOI: 10.1111/all.14016

[Evaluation of a motivational intervention of physical activity program in the treatment of obesity and overweight].

PMID: 31405823
Journal: Hipertension y riesgo vascular
Year: 2020
Reference: Hipertens Riesgo Vasc. 2020 Jan - Mar;37(1):11-16. doi: 10.1016/j.hipert.2019.05.003. Epub 2019 Aug 9.
Impact factor: 0
Publication type: Paper in national publication
Authors: Lopez Tarraga, P J, Madrona-Marcos, F, Panisello-Royo, J, Carbayo-Herencia, J A, Rosich, N, Tarraga-Marcos, L, Castell, E, Alins, J et al.
DOI: 10.1016/j.hipert.2019.05.003

[Motivational intervention for obesity in Primary Care using a physical activity program].

PMID: 32054284
Journal: Nutricion Hospitalaria
Year: 2020
Reference: Nutr Hosp. 2020 Apr 16;37(2):275-284. doi: 10.20960/nh.02601.
Impact factor: 0.888
Publication type: Paper in national publication
Authors: Madrona Marcos, Fatima M feminine, Panisello Royo, Josefa M feminine, Carbayo Herencia, Julio A, Alins, Josep, Tarraga Marcos, Loreto, Castell Panisello, Eudald, Tarraga Lopez, Pedro J et al.
DOI: 10.20960/nh.02601

Treating impulsivity with probiotics in adults (PROBIA): study protocol of a multicenter, double-blind, randomized, placebo-controlled trial.

PMID: 32046750
Journal: Trials
Year: 2020
Reference: Trials. 2020 Feb 11;21(1):161. doi: 10.1186/s13063-019-4040-x.
Impact factor: 1.883
Publication type: Paper in international publication
Authors: Arteaga-Henriquez, Gara, Rosales-Ortiz, Silvia Karina, Arias-Vasquez, Alejandro, Bitter, Istvan, Ginsberg, Ylva, Ibanez-Jimenez, Pol, Kilencz, Tunde, Lavebratt, Catharina, Matura, Silke, Reif, Andreas et al.
DOI: 10.1186/s13063-019-4040-x

Genome-wide analysis of emotional lability in adult attention deficit hyperactivity disorder (ADHD).

PMID: 31085060
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
Year: 2019
Reference: Eur Neuropsychopharmacol. 2019 Jun;29(6):795-802. doi: 10.1016/j.euroneuro.2019.04.004. Epub 2019 May 10.
Impact factor: 4.468
Publication type: Paper in international publication
Authors: Gisbert, Laura, Vilar, Laura, Rovira, Paula, Sanchez-Mora, Cristina, Pagerols, Mireia, Garcia-Martinez, Iris, Richarte, Vanesa, Corrales, Montserrat, Casas, Miguel, Ramos-Quiroga, Josep Antoni et al.
DOI: 10.1016/j.euroneuro.2019.04.004

Cocaine relapse and health-related quality of life: a 23 weeks study.

PMID: 31017271
Journal: ACTAS ESPANOLAS DE PSIQUIATRIA
Year: 2019
Reference: Actas Esp Psiquiatr. 2019 Mar;47(2):37-44. Epub 2019 Mar 1.
Impact factor: 1.479
Publication type: Paper in international publication
Authors: Grau-Lopez, Lara, Roncero, Carlos, Palma-Alvarez, Raul F, Diaz-Moran, Sira, Alvarez, Ana I, Casas, Miguel, Daigre, Constanza, Ros-Cucurull, Elena, Rodriguez-Cintas, Laia et al.
DOI:

Effect of a program of physical activity motivated by lipid parameters of patients with obesity and/or overweight.

PMID: 30971374
Journal: Clinica e investigacion en arteriosclerosis : publ
Year: 2019
Reference: Clin Investig Arterioscler. 2019 Nov - Dec;31(6):245-250. doi: 10.1016/j.arteri.2019.02.002. Epub 2019 Apr 7.
Impact factor: 0
Publication type: Paper in national publication
Authors: Tarraga Lopez, Pedro J, Madrona Marcos, Fatima, Panisello Royo, Josefa M, Tarraga Marcos, M Loreto, Rosich, Nuria, Carbayo Herencia, Julio A, Alins, Josep, Castell, Eudald et al.
DOI: 10.1016/j.arteri.2019.02.002

Epigenetic signature for attention-deficit/hyperactivity disorder: identification of miR-26b-5p, miR-185-5p, and miR-191-5p as potential biomarkers in peripheral blood mononuclear cells.

PMID: 30568281
Journal: NEUROPSYCHOPHARMACOLOGY
Year: 2019
Reference: Neuropsychopharmacology. 2019 Apr;44(5):890-897. doi: 10.1038/s41386-018-0297-0. Epub 2018 Dec 19.
Impact factor: 7.16
Publication type: Paper in international publication
Authors: Franke, Barbara, Arias-Vasquez, Alejandro, Casas, Miguel, Ramos-Quiroga, Josep-Antoni, Ribases, Marta, de la Cruz, Xavier, Padilla, Natalia, Corrales, Montse, Sanchez-Mora, Cristina, Artigas, Maria Soler et al.
DOI: 10.1038/s41386-018-0297-0

Bright light therapy versus physical exercise to prevent co-morbid depression and obesity in adolescents and young adults with attention-deficit / hyperactivity disorder: study protocol for a randomized controlled trial.

PMID: 29482662
Journal: Trials
Year: 2018
Reference: Trials. 2018 Feb 26;19(1):140. doi: 10.1186/s13063-017-2426-1.
Impact factor: 2.067
Publication type: Paper in international publication
Authors: Mayer, Jutta S, Hees, Katharina, Medda, Juliane, Grimm, Oliver, Asherson, Philip, Bellina, Mariano, Colla, Michael, Ibanez, Pol, Koch, Elena, Martinez-Nicolas, Antonio et al.
DOI: 10.1186/s13063-017-2426-1

Anxiety and Depression in Drug-Dependent Patients with Cluster C Personality Disorders.

PMID: 29472875
Journal: Frontiers in Psychiatry
Year: 2018
Reference: Front Psychiatry. 2018 Feb 8;9:19. doi: 10.3389/fpsyt.2018.00019. eCollection 2018.
Impact factor: 2.857
Publication type: Paper in international publication
Authors: Roncero, Carlos, de Miguel, Adelia, Fumero, Ascension, Abad, Alfonso C, Martin, Rita, Bethencourt, Juan Manuel, Grau-Lopez, Lara, Rodriguez-Cintas, Laia, Daigre, Constanza et al.
DOI: 10.3389/fpsyt.2018.00019

Integrative genomic analysis of methylphenidate response in attention-deficit/hyperactivity disorder.

PMID: 29382897
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Jan 30;8(1):1881. doi: 10.1038/s41598-018-20194-7.
Impact factor: 4.122
Publication type: Paper in international publication
Authors: Garcia-Martinez, Iris, Calvo-Sanchez, Eva, Corrales, Montse, da Silva, Bruna Santos, Mota, Nina Roth, Victor, Marcelo Moraes, Rohde, Luis Augusto, Grevet, Eugenio Horacio, Bau, Claiton Henrique Dotto, Cormand, Bru et al.
DOI: 10.1038/s41598-018-20194-7

Harm reduction program use, psychopathology and medical severity in patients with methadone maintenance treatment.

PMID: 29353292
Journal: Adicciones
Year: 2018
Reference: Adicciones. 2018 Jan 15;30(3):197-207. doi: 10.20882/adicciones.897.
Impact factor: 2.021
Publication type: Paper in national publication
Authors: Martinez-Luna, Nieves Gudelia, Rodriguez-Cintas, Laia, Esojo, Abderraman, Palma-Alvarez, Raul Felipe, Robles-Martinez, Maria, Grau-Lopez, Lara, Perea, Marta, Roncero, Carlos et al.
DOI: 10.20882/adicciones.897

Health related quality of life in renal transplantation: 2 years of longitudinal follow-up.

PMID: 28427723
Journal: MEDICINA CLINICA
Year: 2017
Reference: Med Clin (Barc). 2017 Aug 10;149(3):114-118. doi: 10.1016/j.medcli.2017.02.032. Epub 2017 Apr 17.
Impact factor: 1.125
Publication type: Paper in national publication
Authors: Seron, Daniel, Costa-Requena, Gema, Cantarell, M Carmen, Moreso, Francesc, Parramon, Gemma et al.
DOI: 10.1016/j.medcli.2017.02.032

Association Between Vitamin D Status and Schizophrenia: A First Psychotic Episode Study.

PMID: 28406840
Journal: JOURNAL OF NERVOUS AND MENTAL DISEASE
Year: 2017
Reference: J Nerv Ment Dis. 2017 May;205(5):409-412. doi: 10.1097/NMD.0000000000000670.
Impact factor: 1.86
Publication type: Paper in international publication
Authors: Salavert, Jose, Grados, Dolors, Ramiro, Nuria, Carrion, Maria Isabel, Fadeuilhe, Christian, Palma, Felipe, Lopez, Laura, Erra, Alba, Ramirez, Nicolas et al.
DOI: 10.1097/NMD.0000000000000670

HIV And HCV infection among opiate-dependent patients and methadone doses: the PROTEUS study.

PMID: 28393548
Journal: AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
Year: 2017
Reference: AIDS Care. 2017 Dec;29(12):1551-1556. doi: 10.1080/09540121.2017.1313384. Epub 2017 Apr 9.
Impact factor: 1.824
Publication type: Paper in international publication
Authors: Roncero, Carlos, Fuster, Daniel, Palma-Alvarez, Raul Felipe, Rodriguez-Cintas, Laia, Martinez-Luna, Nieves, Alvarez, F Javier et al.
DOI: 10.1080/09540121.2017.1313384

Peripheral levels of BDNF and opiate-use disorder: literature review and update.

PMID: 28306543
Journal: REVIEWS IN THE NEUROSCIENCES
Year: 2017
Reference: Rev Neurosci. 2017 Jul 26;28(5):499-508. doi: 10.1515/revneuro-2016-0078.
Impact factor: 2.546
Publication type: Review in international publication
Authors: Palma-Alvarez, Raul Felipe, Ros-Cucurull, Elena, Amaro-Hosey, Kristopher, Rodriguez-Cintas, Laia, Grau-Lopez, Lara, Corominas-Roso, Margarida, Sanchez-Mora, Cristina, Roncero, Carlos et al.
DOI: 10.1515/revneuro-2016-0078

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News

The new drug improves core symptoms of depression in just three days

This new method improves and streamlines drug development processes

Complemented with the analysis of genetic variants, the work led by Vall d'Hebron establishes the basis for using gene expression as a potential biomarker of risk of developing the disorder.

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