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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Radiologic MS disease activity during natalizumab treatment interruption: findings from RESTORE.

PMID: 25381458
Journal: J NEUROL
Year: 2015
Reference: J Neurol. 2015 Feb;262(2):326-36. doi: 10.1007/s00415-014-7558-6. Epub 2014 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Campagnolo, Denise; Cree, Bruce A C; De Seze, Jerome; Duda, Petra; Fox, Robert J; Gold, Ralf; Hartung, Hans-Peter; Jeffery, Douglas; Kappos, Ludwig; Kaufman, Michael et al.
DOI: 10.1007/s00415-014-7558-6

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study.

PMID: 25877855
Journal: LANCET ONCOLOGY
Year: 2015
Reference: Lancet Oncol. 2015 May;16(5):499-508. doi: 10.1016/S1470-2045(15)70127-0. Epub 2015 Apr 12.
Impact factor: 24.69
Publication type: Paper in international publication
Authors: Laplaige, Philippe, Tabernero, Josep, Yoshino, Takayuki, Cohn, Allen Lee, Obermannova, Radka, Bodoky, Gyorgy, Garcia-Carbonero, Rocio, Ciuleanu, Tudor-Eliade, Portnoy, David C, Van Cutsem, Eric et al.
DOI: 10.1016/S1470-2045(15)70127-0

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study.

PMID: 25877855
Journal: LANCET ONCOL
Year: 2015
Reference: Lancet Oncol. 2015 May;16(5):499-508. doi: 10.1016/S1470-2045(15)70127-0. Epub 2015 Apr 12.
Impact factor:
Publication type: Paper in international publication
Authors: Achille, Emmanuel; Acs, Peter; Ahn, Joong Bae; Al-batran, Salah-eddin; Anderson, Thomas; Andrews, Willard; Atkinson, Victoria; Awasthi, Sanjay; Ayers, John; Azad, Niolfer et al.
DOI: 10.1016/S1470-2045(15)70127-0

Randomized trial of TAS-102 for refractory metastatic colorectal cancer.

PMID: 25970050
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2015
Reference: N Engl J Med. 2015 May 14;372(20):1909-19. doi: 10.1056/NEJMoa1414325.
Impact factor: 55.873
Publication type: Paper in international publication
Authors: Tabernero, Josep, Mayer, Robert J, Van Cutsem, Eric, Falcone, Alfredo, Yoshino, Takayuki, Garcia-Carbonero, Rocio, Mizunuma, Nobuyuki, Yamazaki, Kentaro, Shimada, Yasuhiro, Scheithauer, Werner et al.
DOI: 10.1056/NEJMoa1414325

Randomized trial of TAS-102 for refractory metastatic colorectal cancer.

PMID: 25970050
Journal: NEW ENGL J MED
Year: 2015
Reference: N Engl J Med. 2015 May 14;372(20):1909-19. doi: 10.1056/NEJMoa1414325.
Impact factor:
Publication type: Paper in international publication
Authors: Adenis, Antoine; Andre, Thierry; Baba, Hideo; Baron, Ari D; Benavides, Manuel; Benedetti, Fabio; Bertolini, Alessandro; Bird, Brian; Block, Andreas; Borg, Christophe et al.
DOI: 10.1056/NEJMoa1414325

Rapid resolution of brain ischemic hypoxia after cerebral revascularization in moyamoya disease.

PMID: 25584958
Journal: NEUROSURGERY
Year: 2015
Reference: Neurosurgery. 2015 Mar;76(3):302-12; discussion 312. doi: 10.1227/NEU.0000000000000609.
Impact factor: 3.62
Publication type: Paper in international publication
Authors: Noguer, Montserrat, Arikan, Fuat, Vilalta, Jordi, Torne, Ramon, Sahuquillo, Juan, Lorenzo-Bosquet, Carles et al.
DOI: 10.1227/NEU.0000000000000609

Rapid resolution of brain ischemic hypoxia after cerebral revascularization in moyamoya disease.

PMID: 25584958
Journal: NEUROSURGERY
Year: 2015
Reference: Neurosurgery. 2015 Mar;76(3):302-12; discussion 312. doi: 10.1227/NEU.0000000000000609.
Impact factor:
Publication type: Paper in international publication
Authors: Arikan, Fuat; Lorenzo-Bosquet, Carles; Noguer, Montserrat; Sahuquillo, Juan; Torne, Ramon; Vilalta, Jordi et al.
DOI: 10.1227/NEU.0000000000000609

Rates of faecal colonization by carbapenemase-producing Enterobacteriaceae among patients admitted to ICUs in Spain.

PMID: 26163400
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2015
Reference: J Antimicrob Chemother. 2015 Oct;70(10):2916-8. doi: 10.1093/jac/dkv187. Epub 2015 Jul 9.
Impact factor: 5.313
Publication type: Paper in international publication
Authors: Diaz-Lamas, Ana Maria, Fernandez-Martinez, Marta, Fontanals, Dionisia, Gonzalez-Lopez, Juan Jose, Lopez-Contreras, Joaquin, Martinez-Martinez, Luis, Mora-Rillo, Marta, Munoz, Maria, Navarro, Ferran, Oliver, Antonio et al.
DOI: 10.1093/jac/dkv187

Rates of faecal colonization by carbapenemase-producing Enterobacteriaceae among patients admitted to ICUs in Spain.

PMID: 26163400
Journal: J ANTIMICROB CHEMOTH
Year: 2015
Reference: J Antimicrob Chemother. 2015 Oct;70(10):2916-8. doi: 10.1093/jac/dkv187. Epub 2015 Jul 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alcaraz, Rosa; Aracil, Belen; Bou, German; Conejo, Carmen; Diaz-Lamas, Ana Maria; Fernandez-Martinez, Marta; Fontanals, Dionisia; Gonzalez-Lopez, Juan Jose; Lopez-Contreras, Joaquin; Martinez-Martinez, Luis et al.
DOI: 10.1093/jac/dkv187

Rationale and design of the Cyclosporine to ImpRove Clinical oUtcome in ST-elevation myocardial infarction patients (the CIRCUS trial).

PMID: 26027612
Journal: AMERICAN HEART JOURNAL
Year: 2015
Reference: Am Heart J. 2015 Jun;169(6):758-766.e6. doi: 10.1016/j.ahj.2015.02.020. Epub 2015 Mar 13.
Impact factor: 4.463
Publication type: Clinical Trials
Authors: Aupetit, Jean-Francois, Jouve, Bernard, Motreff, Pascal, Tron, Christophe, Labeque, Jean-Noel, Steg, Pierre G, Cottin, Yves, Range, Gregoire, Clerc, Jerome, Coussement, Patrick et al.
DOI: 10.1016/j.ahj.2015.02.020

Rationale and design of the Cyclosporine to ImpRove Clinical oUtcome in ST-elevation myocardial infarction patients (the CIRCUS trial).

PMID: 26027612
Journal: AM HEART J
Year: 2015
Reference: Am Heart J. 2015 Jun;169(6):758-766.e6. doi: 10.1016/j.ahj.2015.02.020. Epub 2015 Mar 13.
Impact factor:
Publication type: Clinical Trials
Authors: Angoulvant, Denis; Aupetit, Jean-Francois; Barragan, Paul; Beard, Thierry; Belle, Loic; Blanchard, Didier; Bonnefoy-Cudraz, Eric; Boussaha, Inesse; Cayla, Guillaume; Claeys, Marc et al.
DOI: 10.1016/j.ahj.2015.02.020

Rationale and design of the RIBS IV randomised clinical trial (drug-eluting balloons versus everolimus-eluting stents for patients with drug-eluting stent restenosis).

PMID: 25244700
Journal: EuroIntervention
Year: 2015
Reference: EuroIntervention. 2015 Jul;11(3):336-42. doi: 10.4244/EIJY14M09_07.
Impact factor: 3.758
Publication type: Paper in international publication
Authors: Alfonso, Fernando, Perez-Vizcayno, Maria Jose, Cardenas, Alberto, Garcia Del Blanco, Bruno, Garcia-Touchard, Arturo, Lopez-Minguez, Jose Ramon, Rivero, Fernando, Masotti, Monica, Cequier, Angel, Moris, Cesar et al.
DOI: 10.4244/EIJY14M09_07

Rationale and design of the RIBS IV randomised clinical trial (drug-eluting balloons versus everolimus-eluting stents for patients with drug-eluting stent restenosis).

PMID: 25244700
Journal: EUROINTERVENTION
Year: 2015
Reference: EuroIntervention. 2015 Jul;11(3):336-42. doi: 10.4244/EIJY14M09_07.
Impact factor:
Publication type: Paper in international publication
Authors: Alfonso, Fernando; Cardenas, Alberto; Cequier, Angel; Escaned, Javier; Fernandez, Cristina; Fernandez-Ortiz, Antonio; Garcia Del Blanco, Bruno; Garcia-Touchard, Arturo; Gonzalo, Nieves; Jimenez-Quevedo, Pilar et al.
DOI: 10.4244/EIJY14M09_07

Rationale, design and objectives of ARegPKD, a European ARPKD registry study.

PMID: 25886171
Journal: BMC Nephrology
Year: 2015
Reference: BMC Nephrol. 2015 Feb 18;16:22. doi: 10.1186/s12882-015-0002-z.
Impact factor: 1.69
Publication type: Paper in international publication
Authors: Duzova, Ali, Goebel, Heike, Haffner, Dieter, Hero, Barbara, Hoppe, Bernd, Illig, Thomas, Jankauskiene, Augustina, Klopp, Norman, Konig, Jens, Litwin, Mieczyslaw et al.
DOI: 10.1186/s12882-015-0002-z

Rationale, design and objectives of ARegPKD, a European ARPKD registry study.

PMID: 25886171
Journal: BMC NEPHROL
Year: 2015
Reference: BMC Nephrol. 2015 Feb 18;16:22. doi: 10.1186/s12882-015-0002-z.
Impact factor:
Publication type: Paper in international publication
Authors: Anarat, A; Ardissino, G; Ariceta, Gema; Baskin, E; Beck, B; Benz, K; Benzing, T; Bergmann, Carsten; Beringer, O; Bernhardt, W et al.
DOI: 10.1186/s12882-015-0002-z

Real-time assessment of (1)(3)C metabolism reveals an early lactate increase in the brain of rats with acute liver failure.

PMID: 25303736
Journal: NMR IN BIOMEDICINE
Year: 2015
Reference: NMR Biomed. 2015 Jan;28(1):17-23. doi: 10.1002/nbm.3226. Epub 2014 Oct 10.
Impact factor: 3.044
Publication type: Paper in international publication
Authors: Chavarria, Laia, Romero-Gimenez, Jordi, Monteagudo, Eva, Lope-Piedrafita, Silvia, Cordoba, Juan et al.
DOI: 10.1002/nbm.3226

Real-time assessment of (1)(3)C metabolism reveals an early lactate increase in the brain of rats with acute liver failure.

PMID: 25303736
Journal: NMR BIOMED
Year: 2015
Reference: NMR Biomed. 2015 Jan;28(1):17-23. doi: 10.1002/nbm.3226. Epub 2014 Oct 10.
Impact factor:
Publication type: Paper in international publication
Authors: Chavarria, Laia; Cordoba, Juan; Lope-Piedrafita, Silvia; Monteagudo, Eva; Romero-Gimenez, Jordi et al.
DOI: 10.1002/nbm.3226

Recent advances in the treatment of melanoma with BRAF and MEK inhibitors.

PMID: 26488003
Journal: Annals of translational medicine
Year: 2015
Reference: Ann Transl Med. 2015 Sep;3(15):207. doi: 10.3978/j.issn.2305-5839.2015.05.13.
Impact factor: 0
Publication type: Review in international publication
Authors: Munoz-Couselo, Eva, Garcia, Jesus Soberino, Perez-Garcia, Jose Manuel, Cebrian, Vanesa Ortega, Castan, Javier Cortes et al.
DOI: 10.3978/j.issn.2305-5839.2015.05.13

Recent advances in the treatment of melanoma with BRAF and MEK inhibitors.

PMID: 26488003
Journal: Annals of translational medicine
Year: 2015
Reference: Ann Transl Med. 2015 Sep;3(15):207. doi: 10.3978/j.issn.2305-5839.2015.05.13.
Impact factor:
Publication type: Review in international publication
Authors: Castan, Javier Cortes; Cebrian, Vanesa Ortega; Garcia, Jesus Soberino; Munoz-Couselo, Eva; Perez-Garcia, Jose Manuel et al.
DOI: 10.3978/j.issn.2305-5839.2015.05.13

Recognizing the place of trials with treatment of physician's choice as the control arm.

PMID: 25732168
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2015
Reference: J Clin Oncol. 2015 Apr 10;33(11):1300-1. doi: 10.1200/JCO.2014.59.3228. Epub 2015 Mar 2.
Impact factor: 18.428
Publication type: Letter whit IF
Authors: Twelves, Chris, Jove, Maria, Cortes, Javier et al.
DOI: 10.1200/JCO.2014.59.3228

Recognizing the place of trials with treatment of physician's choice as the control arm.

PMID: 25732168
Journal: J CLIN ONCOL
Year: 2015
Reference: J Clin Oncol. 2015 Apr 10;33(11):1300-1. doi: 10.1200/JCO.2014.59.3228. Epub 2015 Mar 2.
Impact factor:
Publication type: Letter whit IF
Authors: Cortes, Javier; Jove, Maria; Twelves, Chris et al.
DOI: 10.1200/JCO.2014.59.3228

Recomendaciones para el uso clínico del microarray genómico en diagnóstico prenatal

PMID: 0003nopmid
Journal: Prog Obstet Ginecol
Year: 2015
Reference: Progresos de Obstetricia y Ginecología, 2015-12-01, Volumen 58, Número 10, Páginas 470-473
Impact factor: 0
Publication type: Paper in national publication
Authors: Plaja Rustein, Alberto, Campo Casanelles, Miguel del, Casals, Elena, Figueras, Francesc, Chica, Rosana de la, Armengol, Lluis, Cirigliano , Vincenzo, Borrell, Antoni et al.
DOI: 10.1016/j.pog.2015.05.003

Recomendaciones para el uso clínico del microarray genómico en diagnóstico prenatal

PMID: 0003nopmid
Journal: Prog Obstet Ginecol
Year: 2015
Reference: Progresos de Obstetricia y Ginecología, 2015-12-01, Volumen 58, Número 10, Páginas 470-473
Impact factor:
Publication type: Paper in national publication
Authors: Armengol, Lluis; Borrell, Antoni; Campo Casanelles, Miguel del; Casals, Elena; Chica, Rosana de la; Cirigliano , Vincenzo; Figueras, Francesc; Plaja Rustein, Alberto et al.
DOI: 10.1016/j.pog.2015.05.003

[Recommendations for bacillus Calmette-Guerin vaccination in children with latent tuberculosis infection].

PMID: 26169597
Journal: ANALES DE PEDIATRIA
Year: 2015
Reference: An Pediatr (Barc). 2015 Oct;83(4):291-2. doi: 10.1016/j.anpedi.2015.06.003. Epub 2015 Jul 11.
Impact factor: 0.833
Publication type: Paper in national publication
Authors: Guarch Ibanez, B, Bruguera Riera, A, Gonzalez Antelo, A, Rodrigo Pendas, J A et al.
DOI: 10.1016/j.anpedi.2015.06.003