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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Effectiveness and Safety of COPD Maintenance Therapy with Tiotropium/Olodaterol versus LABA/ICS in a US Claims Database.

PMID: 33721209
Journal: ADVANCES IN THERAPY
Year: 2021
Reference: Adv Ther. 2021 May;38(5):2249-2270. doi: 10.1007/s12325-021-01646-5. Epub 2021 Mar 15.
Impact factor: 3.847
Publication type: Paper in international publication
Authors: Quint, Jennifer K, Montonen, Jukka, Esposito, Daina B, He, Xintong, Koerner, Leslie, Wallace, Laura, de la Hoz, Alberto, Miravitlles, Marc et al.
DOI: 10.1007/s12325-021-01646-5

Effectiveness of a Telephone-Based Motivational Intervention for Smoking Cessation in Patients With Crohn Disease: A Randomized, Open-Label, Controlled Clinical Trial.

PMID: 34269705
Journal: Gastroenterology Nursing
Year: 2021
Reference: Gastroenterol Nurs. 2021 Nov-Dec 01;44(6):418-425. doi: 10.1097/SGA.0000000000000572.
Impact factor: 0.978
Publication type: Paper in international publication
Authors: Robles Alonso, Virginia, Navarro Correal, Ester, Casellas Jorda, Francesc, Borruel Sainz, Natalia, Sanchez Garcia, Josep Maria, Vila Morte, Genoveva, Fuentelsaz Gallego, Carmen, Ibarz Casas, Arantxa, Herrera de Guise, Claudia et al.
DOI: 10.1097/SGA.0000000000000572

Effectiveness of tianeptine in patients with major depressive disorder and substance use disorder.

PMID: 34195969
Journal: ACTAS ESPANOLAS DE PSIQUIATRIA
Year: 2021
Reference: Actas Esp Psiquiatr. 2021 Jul;49(4):135-144. Epub 2021 Jul 1.
Impact factor: 1.196
Publication type: Paper in international publication
Authors: Roncero, Carlos, Martinez-Raga, Jose, Grau-Lopez, Lara, Vega, Pablo, Basurte, Ignacio, Arias, Francisco, Szerman, Nestor, Algorta, Jaime et al.
DOI:

Effects of Albumin on Survival after a Hepatic Encephalopathy Episode: Randomized Double-Blind Trial and Meta-Analysis.

PMID: 34768404
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Oct 23;10(21). pii: jcm10214885. doi: 10.3390/jcm10214885.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Ventura-Cots, Meritxell, Simon-Talero, Macarena, Poca, Maria, Ariza, Xavier, Masnou, Helena, Sanchez, Jordi, Llop, Elba, Canete, Nuria, Martin-Llahi, Marta, Amador, Alberto et al.
DOI: 10.3390/jcm10214885

Effects of COVID -19 pandemic and lockdown on people with multiple system atrophy participating in a therapeutic education program.

PMID: 33873000
Journal: PARKINSONISM & RELATED DISORDERS
Year: 2021
Reference: Parkinsonism Relat Disord. 2021 May;86:78-80. doi: 10.1016/j.parkreldis.2021.03.021. Epub 2021 Mar 29.
Impact factor: 4.891
Publication type: Letter whit IF
Authors: Ludena, Emma, Camara, Ana, Compta, Yaroslau, Perez-Soriano, Alexandra, Montagut, Nuria, Baixauli, Montserrat, Maragall, Laura, Fernandez, Noemi, Villote, Susana, Ahuir, Maribel et al.
DOI: 10.1016/j.parkreldis.2021.03.021

Effects of COVID-19 lockdown on a bariatric surgery waiting list cohort and its influence in surgical risk perception.

PMID: 33244718
Journal: LANGENBECKS ARCHIVES OF SURGERY
Year: 2021
Reference: Langenbecks Arch Surg. 2021 Mar;406(2):393-400. doi: 10.1007/s00423-020-02040-5. Epub 2020 Nov 26.
Impact factor: 3.445
Publication type: Paper in international publication
Authors: Armengol, Manel, Beisani, Marc, Vilallonga, Ramon, Petrola, Carlos, Acosta, Asuncion, Casimiro Perez, Jose Antonio, Garcia Ruiz de Gordejuela, Amador, Fernandez Quesada, Carlos, Gonzalez, Oscar, Cirera de Tudela, Arturo et al.
DOI: 10.1007/s00423-020-02040-5

Effects of COVID-19 Lockdown on Tumour Burden of Melanoma and Cutaneous Squamous Cell Carcinoma.

PMID: 34396424
Journal: ACTA DERMATO-VENEREOLOGICA
Year: 2021
Reference: Acta Derm Venereol. 2021 Aug 25;101(8):adv00525. doi: 10.2340/00015555-3890.
Impact factor: 4.437
Publication type: Paper in international publication
Authors: Tejera-Vaquerizo, Antonio, Paradela, Sabela, Toll, Agusti, Santos-Juanes, Jorge, Jaka, Ane, Taberner, Rosa, Rodenas-Herranz, Teresa, Garcia-Donoso, Carmen, Puig, Susana, Nagore, Eduardo et al.
DOI: 10.2340/00015555-3890

Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data.

PMID: 32980344
Journal: GASTROENTEROLOGY
Year: 2021
Reference: Gastroenterology. 2021 Jan;160(1):193-205.e10. doi: 10.1053/j.gastro.2020.09.026. Epub 2020 Sep 24.
Impact factor: 22.682
Publication type: Paper in international publication
Authors: Ren, Weixin, Bureau, Christophe, Abraldes, Juan G, Nevens, Frederik, Caca, Karel, Laleman, Wim, Appenrodt, Beate, Luca, Angelo, Vinel, Jean Pierre, Mossner, Joachim et al.
DOI: 10.1053/j.gastro.2020.09.026

Effects of HCV Eradication on Bone mineral density in HIV/HCV Coinfected Patients.

PMID: 32930720
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2021
Reference: Clin Infect Dis. 2021 Oct 5;73(7):e2026-e2033. doi: 10.1093/cid/ciaa1396.
Impact factor: 9.079
Publication type: Paper in international publication
Authors: Carrero, Ana, Berenguer, Juan, Hontanon, Victor, Guardiola, Josep M, Navarro, Jordi, von Wichmann, Miguel A, Tellez, Maria J, Quereda, Carmen, Santos, Ignacio, Sanz, Jose et al.
DOI: 10.1093/cid/ciaa1396

Effects of the Topical Administration of Semaglutide on Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes.

PMID: 34440130
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Jul 31;9(8). pii: biomedicines9080926. doi: 10.3390/biomedicines9080926.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Simo, Rafael, Bogdanov, Patricia, Ramos, Hugo, Huerta, Jordi, Simo-Servat, Olga, Hernandez, Cristina et al.
DOI: 10.3390/biomedicines9080926

Efficacy and safety of abobotulinumtoxinA for upper limb spasticity in children with cerebral palsy: a randomized repeat-treatment study.

PMID: 33206382
Journal: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
Year: 2021
Reference: Dev Med Child Neurol. 2021 May;63(5):592-600. doi: 10.1111/dmcn.14733. Epub 2020 Nov 18.
Impact factor: 5.449
Publication type: Paper in international publication
Authors: Delgado, Mauricio R, Tilton, Ann, Carranza-Del Rio, Jorge, Dursun, Nigar, Bonikowski, Marcin, Aydin, Resa, Maciag-Tymecka, Iwona, Oleszek, Joyce, Dabrowski, Edward, Grandoulier, Anne-Sophie et al.
DOI: 10.1111/dmcn.14733

Efficacy and safety of arimoclomol in Niemann-Pick disease type C: Results from a double-blind, randomized, placebo-controlled, multinational phase 2/3 trial of a novel treatment.

PMID: 34418116
Journal: JOURNAL OF INHERITED METABOLIC DISEASE
Year: 2021
Reference: J Inherit Metab Dis. 2021 Nov;44(6):1463-1480. doi: 10.1002/jimd.12428. Epub 2021 Sep 7.
Impact factor: 4.982
Publication type: Paper in international publication
Authors: Mengel, Eugen, Patterson, Marc C, Da Riol, Rosalia M, Del Toro, Mireia, Deodato, Federica, Gautschi, Matthias, Grunewald, Stephanie, Gronborg, Sabine, Harmatz, Paul, Heron, Benedicte et al.
DOI: 10.1002/jimd.12428

Efficacy and Safety of Atezolizumab Plus Bevacizumab Following Disease Progression on Atezolizumab or Sunitinib Monotherapy in Patients with Metastatic Renal Cell Carcinoma in IMmotion150: A Randomized Phase 2 Clinical Trial.

PMID: 33678522
Journal: EUROPEAN UROLOGY
Year: 2021
Reference: Eur Urol. 2021 May;79(5):665-673. doi: 10.1016/j.eururo.2021.01.003. Epub 2021 Mar 5.
Impact factor: 20.096
Publication type: Paper in international publication
Authors: McDermott, David F, Escudier, Bernard, Motzer, Robert J, Rini, Brian I, Fong, Lawrence, Joseph, Richard W, Pal, Sumanta K, Sznol, Mario, Hainsworth, John, Stadler, Walter M et al.
DOI: 10.1016/j.eururo.2021.01.003

Efficacy and Safety of Cabazitaxel Versus Abiraterone or Enzalutamide in Older Patients with Metastatic Castration-resistant Prostate Cancer in the CARD Study.

PMID: 34274136
Journal: EUROPEAN UROLOGY
Year: 2021
Reference: Eur Urol. 2021 Oct;80(4):497-506. doi: 10.1016/j.eururo.2021.06.021. Epub 2021 Jul 15.
Impact factor: 20.096
Publication type: Paper in international publication
Authors: Ozatilgan, Ayse, Sternberg, Cora N, Castellano, Daniel, de Bono, Johann, Fizazi, Karim, Tombal, Bertrand, Wulfing, Christian, Kramer, Gero, Eymard, Jean-Christophe, Bamias, Aristotelis et al.
DOI: 10.1016/j.eururo.2021.06.021

Efficacy and Safety of Colchicine in Post-acute Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

PMID: 34169101
Journal: Frontiers in Cardiovascular Medicine
Year: 2021
Reference: Front Cardiovasc Med. 2021 Jun 8;8:676771. doi: 10.3389/fcvm.2021.676771. eCollection 2021.
Impact factor: 6.05
Publication type: Review in international publication
Authors: Diaz-Arocutipa, Carlos, Benites-Meza, Jerry K, Chambergo-Michilot, Diego, Barboza, Joshuan J, Pasupuleti, Vinay, Bueno, Hector, Sambola, Antonia, Hernandez, Adrian V et al.
DOI: 10.3389/fcvm.2021.676771

Efficacy and safety of early target-controlled plasma volume replacement with a balanced gelatine solution versus a balanced electrolyte solution in patients with severe sepsis/septic shock: study protocol, design, and rationale of a prospective, randomized, controlled, double-blind, multicentric, international clinical trial : GENIUS-Gelatine use in ICU and sepsis.

PMID: 34078421
Journal: Trials
Year: 2021
Reference: Trials. 2021 Jun 2;22(1):376. doi: 10.1186/s13063-021-05311-8.
Impact factor: 2.279
Publication type: Paper in international publication
Authors: Zacharowski, Kai, Ichai, Carole, Asehnoune, Karim, Cerny, Vladimir, Dembinski, Rolf, Ferrer Roca, Ricard, Fries, Dietmar, Molnar, Zsolt, Rosenberger, Peter, Sanchez-Sanchez, Manuel et al.
DOI: 10.1186/s13063-021-05311-8

Efficacy and safety of high-dose lanreotide autogel in patients with progressive pancreatic or midgut neuroendocrine tumours: CLARINET FORTE phase 2 study results.

PMID: 34597974
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2021
Reference: Eur J Cancer. 2021 Nov;157:403-414. doi: 10.1016/j.ejca.2021.06.056. Epub 2021 Sep 28.
Impact factor: 9.162
Publication type: Paper in international publication
Authors: Pavel, Marianne, Cwikla, Jaroslaw B, Borbath, Ivan, Shah, Tahir, Pape, Ulrich F, Capdevila, Jaume, Panzuto, Francesco, Truong Thanh, Xuan-Mai, Houchard, Aude, Ruszniewski, Philippe et al.
DOI: 10.1016/j.ejca.2021.06.056

Efficacy and safety of lurbinectedin and doxorubicin in relapsed small cell lung cancer. Results from an expansion cohort of a phase I study.

PMID: 33704620
Journal: INVESTIGATIONAL NEW DRUGS
Year: 2021
Reference: Invest New Drugs. 2021 Oct;39(5):1275-1283. doi: 10.1007/s10637-020-01025-x. Epub 2021 Mar 11.
Impact factor: 3.85
Publication type: Paper in international publication
Authors: Olmedo, Maria Eugenia, Forster, Martin, Moreno, Victor, Lopez-Criado, Maria Pilar, Brana, Irene, Flynn, Michael, Doger, Bernard, de Miguel, Maria, Lopez-Vilarino, Jose Antonio, Nunez, Rafael et al.
DOI: 10.1007/s10637-020-01025-x

Efficacy and safety of once-daily single-inhaler triple therapy in patients with inadequately controlled asthma: the CAPTAIN trial.

PMID: 34295395
Journal: Breathe (Sheffield, England)
Year: 2021
Reference: Breathe (Sheff). 2021 Mar;17(1):200279. doi: 10.1183/20734735.0279-2020.
Impact factor: 0
Publication type: Letter or abstract
Authors: Pilia, Maria Florencia, Ojanguren, Inigo et al.
DOI: 10.1183/20734735.0279-2020

Efficacy and safety of opioid therapy guided by pharmacogenetics: a systematic review.

PMID: 34013775
Journal: PHARMACOGENOMICS
Year: 2021
Reference: Pharmacogenomics. 2021 Jun;22(9):573-586. doi: 10.2217/pgs-2021-0021. Epub 2021 May 20.
Impact factor: 2.533
Publication type: Review in international publication
Authors: Rodriguez Cairoli, Federico, Appiani, Francisco, Sambade, Juan Manuel, Comande, Daniel, Camacho Arteaga, Lina, Ciapponi, Agustin et al.
DOI: 10.2217/pgs-2021-0021

Efficacy and Safety of PCSK9 Inhibitors in Hypercholesterolemia Associated With Refractory Nephrotic Syndrome.

PMID: 33426389
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Jatem, Elias, Lima, Joan, Montoro, Bruno, Torres-Bondia, Francisco, Segarra, Alfons et al.
DOI: 10.1016/j.ekir.2020.09.046

Efficacy and safety of pembrolizumab in patients with advanced mesothelioma in the open-label, single-arm, phase 2 KEYNOTE-158 study.

PMID: 33836153
Journal: Lancet Respiratory Medicine
Year: 2021
Reference: Lancet Respir Med. 2021 Jun;9(6):613-621. doi: 10.1016/S2213-2600(20)30515-4. Epub 2021 Apr 6.
Impact factor: 30.7
Publication type: Paper in international publication
Authors: Yap, Timothy A, Nakagawa, Kazuhiko, Fujimoto, Nobukazu, Kuribayashi, Kozo, Guren, Tormod Kyrre, Shapira-Frommer, Ronnie, Gao, Bo, Kao, Steven, Matos, Ignacio, Planchard, David et al.
DOI: 10.1016/S2213-2600(20)30515-4

Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS).

PMID: 34030643
Journal: BMC CANCER
Year: 2021
Reference: BMC Cancer. 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z.
Impact factor: 4.43
Publication type: Paper in international publication
Authors: Grivas, P, Loriot, Y, Morales-Barrera, R, Teo, M Y, Zakharia, Y, Feyerabend, S, Vogelzang, N J, Grande, E, Adra, N, Alva, A et al.
DOI: 10.1186/s12885-021-08085-z

Efficacy and safety of switching to dolutegravir plus lamivudine versus continuing triple antiretroviral therapy in virologically suppressed adults with HIV at 48 weeks (DOLAM): a randomised non-inferiority trial.

PMID: 34358497
Journal: Lancet HIV
Year: 2021
Reference: Lancet HIV. 2021 Aug;8(8):e463-e473. doi: 10.1016/S2352-3018(21)00100-4.
Impact factor: 12.767
Publication type: Paper in international publication
Authors: Rojas, Jhon, de Lazzari, Elisa, Negredo, Eugenia, Domingo, Pere, Tiraboschi, Juan, Ribera, Esteve, Abdulghani, Nadia, Podzamczer, Daniel, Gutierrez, Maria M, Paredes, Roger et al.
DOI: 10.1016/S2352-3018(21)00100-4

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