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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Fetal heart rate monitoring during fetoscopic repair of open spinal neural tube defects: a single-centre observational cohort study.

PMID: 34175576
Journal: INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
Year: 2021
Reference: Int J Obstet Anesth. 2021 Nov;48:103195. doi: 10.1016/j.ijoa.2021.103195. Epub 2021 Jun 8.
Impact factor: 2.603
Publication type: Paper in international publication
Authors: Maiz, N, Pascual, M, Perera, R, Arevalo, S, Gine, C, Molino, J A, Lopez, M, Carreras, E, Manrique, S, Suarez, E et al.
DOI: 10.1016/j.ijoa.2021.103195

Fever without source as the first manifestation of SARS-CoV-2 infection in infants less than 90 days old.

PMID: 33606120
Journal: EUROPEAN JOURNAL OF PEDIATRICS
Year: 2021
Reference: Eur J Pediatr. 2021 Jul;180(7):2099-2106. doi: 10.1007/s00431-021-03973-9. Epub 2021 Feb 19.
Impact factor: 3.183
Publication type: Paper in international publication
Authors: Tagarro, Alfredo, Delgado, Rafael, Blazquez-Gamero, Daniel, Epalza, Cristina, Cadenas, Jose Antonio Alonso, Gero, Lourdes Calleja, Calvo, Cristina, Rodriguez-Molino, Paula, Mendez, Maria, Santos, Maria Del Mar et al.
DOI: 10.1007/s00431-021-03973-9

Final results of the double-blind placebo-controlled randomized phase 2 LOTUS trial of first-line ipatasertib plus paclitaxel for inoperable locally advanced/metastatic triple-negative breast cancer.

PMID: 34264439
Journal: BREAST CANCER RESEARCH AND TREATMENT
Year: 2021
Reference: Breast Cancer Res Treat. 2021 Sep;189(2):377-386. doi: 10.1007/s10549-021-06143-5. Epub 2021 Jul 15.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Valero, V, Vidal, G, Figlin, R, Allison, M A K, Chan, D, Cobleigh, M, Hansen, V, Iannotti, N, Lawler, W, Salkini, M et al.
DOI: 10.1007/s10549-021-06143-5

Finding the bubble: atypical and unusual extrapulmonary air in the chest.

PMID: 34246426
Journal: Radiologia
Year: 2021
Reference: Radiologia (Engl Ed). 2021 Jul-Aug;63(4):358-369. doi: 10.1016/j.rxeng.2021.02.005.
Impact factor: 0
Publication type: Letter or abstract
Authors: Varona Porres, D, Persiva, O, Sanchez, A L, Cabanzo, L, Pallisa, E, Andreu, J et al.
DOI: 10.1016/j.rxeng.2021.02.005

First documented outbreak of arthritis caused by Kingella kingae in a Spanish childcare center.

PMID: 33413991
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2021 Jan 4. pii: S0213-005X(20)30407-9. doi: 10.1016/j.eimc.2020.11.006.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Guarch-Ibanez, Borja, Cabacas, Alicia, Gonzalez-Lopez, Juan Jose, Garcia-Gonzalez, Maria Del Mar, Mora, Carme, Villalobos, Pilar et al.
DOI: 10.1016/j.eimc.2020.11.006

First Nationwide Molecular Screening Program in Spain for Patients With Advanced Breast Cancer: Results From the AGATA SOLTI-1301 Study.

PMID: 34804931
Journal: Frontiers in Oncology
Year: 2021
Reference: Front Oncol. 2021 Nov 4;11:744112. doi: 10.3389/fonc.2021.744112. eCollection 2021.
Impact factor: 6.244
Publication type: Paper in international publication
Authors: Burgues, Octavio, Pernas, Sonia, Villagrasa, Patricia, Vivancos, Ana, Scaltriti, Maurizio, Rodon, Jordi, Pare, Laia, Duenas, Marta, Vidal, Maria, Cejalvo, Juan Miguel et al.
DOI: 10.3389/fonc.2021.744112

First-In-Human Phase I Study of a Next-Generation, Oral, TGFbeta Receptor 1 Inhibitor, LY3200882, in Patients with Advanced Cancer.

PMID: 34548321
Journal: CLINICAL CANCER RESEARCH
Year: 2021
Reference: Clin Cancer Res. 2021 Dec 15;27(24):6666-6676. doi: 10.1158/1078-0432.CCR-21-1504. Epub 2021 Sep 21.
Impact factor: 12.531
Publication type: Paper in international publication
Authors: Simonelli, Matteo, Cosman, Rasha, van der Westhuizen, Andre, Atkinson, Victoria, Carpentier, Antoine F, Lohr, Mario, Redman, Rebecca, Mason, Warren, Cervantes, Andres, Le Rhun, Emilie et al.
DOI: 10.1158/1078-0432.CCR-21-1504

First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors.

PMID: 33301375
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2021
Reference: J Clin Oncol. 2021 Jan 10;39(2):145-154. doi: 10.1200/JCO.20.00596. Epub 2020 Dec 10.
Impact factor: 44.544
Publication type: Paper in international publication
Authors: Stumpp, Michael T, Harstrick, Andreas, Azaro, Analia, Fischer, Stefanie, Omlin, Aurelius, Leupin, Nicolas, Dawson, Keith M, Fiedler, Ulrike, Zitt, Christof, Baird, Richard D et al.
DOI: 10.1200/JCO.20.00596

First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas.

PMID: 34389618
Journal: Journal for ImmunoTherapy of Cancer
Year: 2021
Reference: J Immunother Cancer. 2021 Aug;9(8). pii: jitc-2021-002863. doi: 10.1136/jitc-2021-002863.
Impact factor: 13.751
Publication type: Paper in international publication
Authors: Piha-Paul, Sarina A, Geva, Ravit, Tan, Tira J, Lim, Darren Wt, Hierro, Cinta, Doi, Toshikiko, Rahma, Osama, Lesokhin, Alexander, Luke, Jason John, Otero, Javier et al.
DOI: 10.1136/jitc-2021-002863

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial.

PMID: 33476593
Journal: LANCET ONCOLOGY
Year: 2021
Reference: Lancet Oncol. 2021 Feb;22(2):198-211. doi: 10.1016/S1470-2045(20)30641-0. Epub 2021 Jan 18.
Impact factor: 41.316
Publication type: Paper in international publication
Authors: Oukessou, Abderrahim, Yan, Jinchun, Reck, Martin, Agrawal, Shruti, Meadows-Shropshire, Stephanie, Carbone, David P, John, Thomas, Paz-Ares, Luis, Ciuleanu, Tudor-Eliade, Cobo, Manuel et al.
DOI: 10.1016/S1470-2045(20)30641-0

First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update.

PMID: 34607285
Journal: ESMO Open
Year: 2021
Reference: ESMO Open. 2021 Oct;6(5):100273. doi: 10.1016/j.esmoop.2021.100273. Epub 2021 Oct 1.
Impact factor: 6.54
Publication type: Paper in international publication
Authors: Tran, P, John, T, Zhang, X, Marimuthu, S, Memaj, A, Carbone, D P, Reck, M, Ciuleanu, T-E, Cobo, M, Schenker, M et al.
DOI: 10.1016/j.esmoop.2021.100273

Fit-for-Discharge Criteria after Esophagectomy: An International Expert Delphi Consensus.

PMID: 32960264
Journal: DISEASES OF THE ESOPHAGUS
Year: 2021
Reference: Dis Esophagus. 2021 Jun 14;34(6). pii: 5909885. doi: 10.1093/dote/doaa101.
Impact factor: 3.429
Publication type: Paper in international publication
Authors: van Veer, H, Low, D E, Luyer, M, Markar, S R, Monig, S P, Moorthy, K, Morse, C R, Muller-Stich, B P, Nafteux, P, Nieponice, A et al.
DOI: 10.1093/dote/doaa101

Five-Year Outcomes From the Randomized, Phase III Trials CheckMate 017 and 057: Nivolumab Versus Docetaxel in Previously Treated Non-Small-Cell Lung Cancer.

PMID: 33449799
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2021
Reference: J Clin Oncol. 2021 Mar 1;39(7):723-733. doi: 10.1200/JCO.20.01605. Epub 2021 Jan 15.
Impact factor: 44.544
Publication type: Paper in international publication
Authors: Burgio, Marco Angelo, Borghaei, Hossein, Gettinger, Scott, Vokes, Everett E, Chow, Laura Q M, Marimuthu, Sathiya, Arrieta, Oscar, Frontera, Osvaldo Aren, Chiari, Rita, Butts, Charles et al.
DOI: 10.1200/JCO.20.01605

Five-year prognosis after TIA or minor ischemic stroke in Asian and non-Asian countries.

PMID: 33046613
Journal: NEUROLOGY
Year: 2021
Reference: Neurology. 2021 Jan 5;96(1):e54-e66. doi: 10.1212/WNL.0000000000010995. Epub 2020 Oct 12.
Impact factor: 9.91
Publication type: Paper in international publication
Authors: Caplan, Louis R, Hoshino, Takao, Uchiyama, Shinichiro, Wong, Lawrence K S, Kitagawa, Kazuo, Charles, Hugo, Labreuche, Julien, Lavallee, Philippa C, Albers, Gregory W, Hennerici, Michael G et al.
DOI: 10.1212/WNL.0000000000010995

Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study.

PMID: 34302787
Journal: LANCET NEUROLOGY
Year: 2021
Reference: Lancet Neurol. 2021 Aug;20(8):627-638. doi: 10.1016/S1474-4422(21)00162-9.
Impact factor: 44.182
Publication type: Paper in international publication
Authors: Frisvold, Shirin, Wiegers, Eveline Janine Anna, Lingsma, Hester Floor, Huijben, Jilske Antonia, Cooper, David James, Citerio, Giuseppe, Furmanov, Alex, Verheyden, Jan, Misset, Benoit, Ledoux, Didier et al.
DOI: 10.1016/S1474-4422(21)00162-9

Fluorescence-based bowel anastomosis perfusion evaluation: results from the IHU-IRCAD-EAES EURO-FIGS registry.

PMID: 33492508
Journal: SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
Year: 2021
Reference: Surg Endosc. 2021 Dec;35(12):7142-7153. doi: 10.1007/s00464-020-08234-8. Epub 2021 Jan 25.
Impact factor: 4.584
Publication type: Paper in international publication
Authors: de Manzini, Nicolo, Spota, Andrea, Al-Taher, Mahdi, Felli, Eric, Morales Conde, Salvador, Dal Dosso, Ivano, Moretto, Gianluigi, Spinoglio, Giuseppe, Baiocchi, Gianluca, Vilallonga, Ramon et al.
DOI: 10.1007/s00464-020-08234-8

Focal and segmental glomerulosclerosis associated with COVID-19 infection.

PMID: 33888348
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 Apr 19. pii: S0211-6995(21)00058-8. doi: 10.1016/j.nefro.2021.03.002.
Impact factor: 2.033
Publication type: Letter or abstract
Authors: LeonRoman, Juan, Vergara, Ander, Agraz, Irene, Garcia-Carro, Clara, Bermejo, Sheila, Gabaldon, Alejandra, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2021.03.002

Focal and segmental glomerulosclerosis associated with COVID-19 infection.

PMID: 33888348
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 Apr 19;41(6):706-8. doi: 10.1016/j.nefro.2021.03.002.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Agraz, Irene; Bermejo, Sheila; Gabaldon, Alejandra; Garcia-Carro, Clara; LeonRoman, Juan; Soler, Maria Jose; Vergara, Ander et al.
DOI: 10.1016/j.nefro.2021.03.002

Follicular Thyroid Carcinoma Metastases on Round Ligament of Liver.

PMID: 33512955
Journal: CLINICAL NUCLEAR MEDICINE
Year: 2021
Reference: Clin Nucl Med. 2021 Apr 1;46(4):326-328. doi: 10.1097/RLU.0000000000003526.
Impact factor: 7.794
Publication type: Letter or abstract
Authors: Monturiol-Duran, Jaime Alejando, Iglesias-Felip, Carmela, Villasboas-Rosciolesi, Diego, Castell-Conesa, Joan, Garcia-Burillo, Amparo et al.
DOI: 10.1097/RLU.0000000000003526

Food groups associated with immune-mediated inflammatory diseases: a Mendelian randomization and disease severity study.

PMID: 33893449
Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION
Year: 2021
Reference: Eur J Clin Nutr. 2021 Sep;75(9):1368-1382. doi: 10.1038/s41430-021-00913-6. Epub 2021 Apr 23.
Impact factor: 4.016
Publication type: Paper in international publication
Authors: Domenech, Eugeni, Julia, Antonio, Martinez-Mateu, Sergio H, Blanco, Francisco, Gratacos, Jordi, Blanco, Ricardo, Taboada, Victor Martinez, Fernandez, Emilia, Unamuno, Pablo, Gonzalez, Isidoro et al.
DOI: 10.1038/s41430-021-00913-6

Food-dependent NSAID-induced hypersensitivity reactions (FDNIH): unraveling the clinical features and risk factors.

PMID: 33289951
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 May;76(5):1480-1492. doi: 10.1111/all.14689. Epub 2020 Dec 22.
Impact factor: 13.146
Publication type: Paper in international publication
Authors: Sanchez-Lopez, Jaime, Araujo, Giovanna, Cardona, Victoria, Garcia-Moral, Alba, Casas-Saucedo, Rocio, Guilarte, Mar, Jose Torres, Maria, Dona, Inmaculada, Picado, Cesar, Pascal, Mariona et al.
DOI: 10.1111/all.14689

Food-induced anaphylaxis morbidity: emergency department and hospitalizations data support preventive strategies.

PMID: 34142390
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2021
Reference: Pediatr Allergy Immunol. 2021 Nov;32(8):1730-1742. doi: 10.1111/pai.13578. Epub 2021 Jul 21.
Impact factor: 6.377
Publication type: Paper in international publication
Authors: Tanno, Luciana Kase, Clark, Evangeline, Mamodaly, Myriam, Cardona, Victoria, Ebisawa, Motohiro, Asontegui, Ignacio, Sanchez-Borges, Mario, Santos, Alexandra F, Fiocchi, Alessandro, Worm, Margitta et al.
DOI: 10.1111/pai.13578

Formation and evolution of the nanoparticle environmental corona: The case of Au and humic acid.

PMID: 33736322
Journal: SCIENCE OF THE TOTAL ENVIRONMENT
Year: 2021
Reference: Sci Total Environ. 2021 May 10;768:144792. doi: 10.1016/j.scitotenv.2020.144792. Epub 2021 Jan 27.
Impact factor: 7.963
Publication type: Paper in international publication
Authors: Barbero, Francesco, Mayall, Craig, Drobne, Damjana, Saiz-Poseu, Javier, Bastus, Neus G, Puntes, Victor et al.
DOI: 10.1016/j.scitotenv.2020.144792

Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase-Associated Neurodegeneration.

PMID: 33200489
Journal: MOVEMENT DISORDERS
Year: 2021
Reference: Mov Disord. 2021 Jun;36(6):1342-1352. doi: 10.1002/mds.28392. Epub 2020 Nov 16.
Impact factor: 10.338
Publication type: Paper in international publication
Authors: Klopstock, Thomas, Videnovic, Aleksandar, Bischoff, Almut Turid, Bonnet, Cecilia, Cif, Laura, Greblikas, Feriandas, Burns, Colleen, Comella, Cynthia, Correa-Vela, Marta, Escolar, Maria L et al.
DOI: 10.1002/mds.28392