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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Identification of Recent Tuberculosis Exposure Using QuantiFERON-TB Gold Plus, a Multicenter Study.

PMID: 34756079
Journal: Microbiology Spectrum
Year: 2021
Reference: Microbiol Spectr. 2021 Dec 22;9(3):e0097221. doi: 10.1128/Spectrum.00972-21. Epub 2021 Nov 10.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Balcells, Maria Elvira, Gazel, Deniz, Montiel, Natalia, Vicente, Diego, Goic-Barisic, Ivana, Schon, Thomas, Paues, Jakob, Marekovic, Ivana, Cacho-Calvo, Juana, Barac, Aleksandra et al.
DOI: 10.1128/Spectrum.00972-21

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis.

PMID: 34322119
Journal: Frontiers in Immunology
Year: 2021
Reference: Front Immunol. 2021 Jul 12;12:685139. doi: 10.3389/fimmu.2021.685139. eCollection 2021.
Impact factor: 7.561
Publication type: Paper in international publication
Authors: Picon, Carmen, Tejeda-Velarde, Amalia, Fernandez-Velasco, Jose Ignacio, Comabella, Manuel, Alvarez-Lafuente, Roberto, Quintana, Ester, Sainz de la Maza, Susana, Monreal, Enric, Villarrubia, Noelia, Alvarez-Cermeno, Jose Carlos et al.
DOI: 10.3389/fimmu.2021.685139

Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis.

PMID: 33892786
Journal: Clinical Epigenetics
Year: 2021
Reference: Clin Epigenetics. 2021 Apr 23;13(1):88. doi: 10.1186/s13148-021-01070-0.
Impact factor: 6.551
Publication type: Paper in international publication
Authors: Bazzocco, Sarah, Dopeso, Higinio, Martinez-Barriocanal, Agueda, Anguita, Estefania, Nieto, Rocio, Li, Jing, Garcia-Vidal, Elia, Maggio, Valentina, Rodrigues, Paulo, de Marcondes, Priscila Guimaraes et al.
DOI: 10.1186/s13148-021-01070-0

Identifying and preventing burnout in young oncologists, an overwhelming challenge in the COVID-19 era: a study of the Spanish Society of Medical Oncology (SEOM).

PMID: 34325108
Journal: ESMO Open
Year: 2021
Reference: ESMO Open. 2021 Aug;6(4):100215. doi: 10.1016/j.esmoop.2021.100215. Epub 2021 Jul 26.
Impact factor: 6.54
Publication type: Paper in international publication
Authors: Remon, J, Rogado, J, Sanchez, D A, Sanchez-Canovas, M, Sanz-Garcia, E, Sesma, A, Tarazona, N, Cotes, A, Gonzalez, E, Bosch-Barrera, J et al.
DOI: 10.1016/j.esmoop.2021.100215

Identifying comorbidities and lifestyle factors contributing to the cognitive profile of early Parkinson's disease.

PMID: 34879838
Journal: BMC Neurology
Year: 2021
Reference: BMC Neurol. 2021 Dec 8;21(1):477. doi: 10.1186/s12883-021-02485-1.
Impact factor: 2.474
Publication type: Paper in international publication
Authors: Martinez-Horta, Saul, Bejr-Kasem, Helena, Horta-Barba, Andrea, Pascual-Sedano, Berta, Santos-Garcia, Diego, de Deus-Fonticoba, Teresa, Jesus, Silvia, Aguilar, Miquel, Planellas, Lluis, Garcia-Caldentey, Juan et al.
DOI: 10.1186/s12883-021-02485-1

Identifying key unmet needs and value drivers in the treatment of focal-onset seizures (FOS) in patients with drug-resistant epilepsy (DRE) in Spain through Multi-Criteria Decision Analysis (MCDA).

PMID: 34371462
Journal: EPILEPSY & BEHAVIOR
Year: 2021
Reference: Epilepsy Behav. 2021 Sep;122:108222. doi: 10.1016/j.yebeh.2021.108222. Epub 2021 Aug 6.
Impact factor: 2.937
Publication type: Paper in international publication
Authors: Villanueva, Vicente, Carreno, Mar, Gil-Nagel, Antonio, Serrano-Castro, Pedro Jesus, Serratosa, Jose Maria, Toledo, Manuel, Alvarez-Baron, Elena, Gil, Alicia, Subias-Labazuy, Silvia et al.
DOI: 10.1016/j.yebeh.2021.108222

Identifying mindfulness and acceptance as mediators between negative affect, functional disability and emotional distress in patients with fibromyalgia.

PMID: 34796836
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2021
Reference: Clin Exp Rheumatol. 2021 Nov 18. pii: 17661.
Impact factor: 4.473
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Alegre-Martin, Jose, Calvo, Natalia, Maurel, Sara, Saez-Francas, Naia et al.
DOI:

IgG4-Related Disease, A Single-Center Experience.

PMID: 30585995
Journal: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
Year: 2021
Reference: J Clin Rheumatol. 2021 Dec 1;27(8S):S590-S591. doi: 10.1097/RHU.0000000000000970.
Impact factor: 3.517
Publication type: Letter whit IF
Authors: Fernandez-Codina, Andreu, Haig, Sarah, Pope, Janet E, Barra, Lillian et al.
DOI: 10.1097/RHU.0000000000000970

Imaging and Biomarkers in Acute Aortic Syndromes: Diagnostic and Prognostic Implications.

PMID: 32958324
Journal: CURRENT PROBLEMS IN CARDIOLOGY
Year: 2021
Reference: Curr Probl Cardiol. 2021 Mar;46(3):100654. doi: 10.1016/j.cpcardiol.2020.100654. Epub 2020 Jul 22.
Impact factor: 5.2
Publication type: Review in international publication
Authors: Bossone, Eduardo, Czerny, Martin, Lerakis, Stamatios, Rodriguez-Palomares, Jose, Kukar, Nina, Ranieri, Brigida, Russo, Valentina, Punzo, Bruna, Cocchia, Rosangela, Cademartiri, Filippo et al.
DOI: 10.1016/j.cpcardiol.2020.100654

IMbrave 151: a randomized phase II trial of atezolizumab combined with bevacizumab and chemotherapy in patients with advanced biliary tract cancer.

PMID: 34377158
Journal: Therapeutic Advances in Medical Oncology
Year: 2021
Reference: Ther Adv Med Oncol. 2021 Jul 31;13:17588359211036544. doi: 10.1177/17588359211036544. eCollection 2021.
Impact factor: 8.168
Publication type: Paper in international publication
Authors: Hack, Stephen P, Verret, Wendy, Mulla, Sohail, Liu, Bo, Wang, Yulei, Macarulla, Teresa, Ren, Zhenggang, El-Khoueiry, Anthony B, Zhu, Andrew X et al.
DOI: 10.1177/17588359211036544

Immune analysis of lymph nodes in relation to the presence or absence of tumor infiltrating lymphocytes in triple-negative breast cancer.

PMID: 33743482
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2021
Reference: Eur J Cancer. 2021 May;148:134-145. doi: 10.1016/j.ejca.2021.01.037. Epub 2021 Mar 17.
Impact factor: 9.162
Publication type: Paper in international publication
Authors: Munoz-Couselo, Eva, Perez-Garcia, Jose, Marti, Merce, Blanco-Heredia, Juan, Anjos, Carla Dos, Vazquez, Miguel, De Mattos-Arruda, Leticia, Cortes, Javier, Curigliano, Giuseppe, Schmid, Peter et al.
DOI: 10.1016/j.ejca.2021.01.037

Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment.

PMID: 33686071
Journal: Nature Communications
Year: 2021
Reference: Nat Commun. 2021 Mar 8;12(1):1503. doi: 10.1038/s41467-021-21789-x.
Impact factor: 14.919
Publication type: Paper in international publication
Authors: Pedrosa, Leire, Iurlaro, Raffaella, Martinez-Ricarte, Francisco, Escudero, Laura, Cordero, Esteban, Cicuendez, Marta, Ruiz, Sara, Parra, Genis, Nuciforo, Paolo, Gonzalez, Josep et al.
DOI: 10.1038/s41467-021-21789-x

Immune microenvironment characterisation and dynamics during anti-HER2-based neoadjuvant treatment in HER2-positive breast cancer.

PMID: 33742063
Journal: npj Precision Oncology
Year: 2021
Reference: NPJ Precis Oncol. 2021 Mar 19;5(1):23. doi: 10.1038/s41698-021-00163-6.
Impact factor: 8.254
Publication type: Paper in international publication
Authors: Martinez, E, Villagrasa, P, Prat, A, Nuciforo, P, Alarcon, J, Manso, L, Morales, S, Griguolo, G, Serna, G, Pascual, T et al.
DOI: 10.1038/s41698-021-00163-6

Immunogenetic characterization of clonal plasma cells in systemic light-chain amyloidosis.

PMID: 32203144
Journal: LEUKEMIA
Year: 2021
Reference: Leukemia. 2021 Jan;35(1):245-249. doi: 10.1038/s41375-020-0800-6. Epub 2020 Mar 19.
Impact factor: 11.528
Publication type: Letter whit IF
Authors: Lasa, Marta, Onecha, Esther, Lecumberri, Ramon, Prosper, Felipe, Ocio, Enrique M, Gonzalez, Maria Esther, Garcia de Coca, Alfonso, De La Rubia, Javier, Gironella, Mercedes, Palomera, Luis et al.
DOI: 10.1038/s41375-020-0800-6

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial.

PMID: 34181880
Journal: LANCET
Year: 2021
Reference: Lancet. 2021 Jul 10;398(10295):121-130. doi: 10.1016/S0140-6736(21)01420-3. Epub 2021 Jun 25.
Impact factor: 79.323
Publication type: Paper in international publication
Authors: Temprano, Mikel, Borobia, Alberto M, Carcas, Antonio J, Perez-Olmeda, Mayte, Castano, Luis, Bertran, Maria Jesus, Garcia-Perez, Javier, Campins, Magdalena, Portoles, Antonio, Gonzalez-Perez, Maria et al.
DOI: 10.1016/S0140-6736(21)01420-3

Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer.

PMID: 33858677
Journal: GYNECOLOGIC ONCOLOGY
Year: 2021
Reference: Gynecol Oncol. 2021 Jun;161(3):787-794. doi: 10.1016/j.ygyno.2021.03.031. Epub 2021 Apr 12.
Impact factor: 5.482
Publication type: Paper in international publication
Authors: Matias-Guiu, X, Amant, F, Snijders, M P L M, Kusters-Vandevelde, H V N, Reijnen, C, Pijnenborg, J M A, van der Wurff, A A, Hausnerova, J, Weinberger, V, Vrede, S W et al.
DOI: 10.1016/j.ygyno.2021.03.031

Immunological and genetic kinetics from diagnosis to clinical progression in chronic lymphocytic leukemia.

PMID: 34016160
Journal: Biomarker Research
Year: 2021
Reference: Biomark Res. 2021 May 20;9(1):37. doi: 10.1186/s40364-021-00290-z.
Impact factor: 6.148
Publication type: Paper in international publication
Authors: Franco-Jarava, Clara, Jimenez, Isabel, Tazon-Vega, Barbara, Abrisqueta, Pau, Nieto, Juan C, Bobillo, Sabela, Palacio-Garcia, Carles, Carabia, Julia, Valdes-Mas, Rafael, Munuera, Magdalena et al.
DOI: 10.1186/s40364-021-00290-z

Immunomodulatory Effects Associated with Cladribine Treatment.

PMID: 34943995
Journal: Cells
Year: 2021
Reference: Cells. 2021 Dec 10;10(12). pii: cells10123488. doi: 10.3390/cells10123488.
Impact factor: 6.6
Publication type: Paper in international publication
Authors: Fissolo, Nicolas, Calvo-Barreiro, Laura, Eixarch, Herena, Boschert, Ursula, Espejo, Carmen, Montalban, Xavier, Comabella, Manuel et al.
DOI: 10.3390/cells10123488

Immunosenescence in multiple sclerosis: The identification of new therapeutic targets.

PMID: 34237417
Journal: AUTOIMMUNITY REVIEWS
Year: 2021
Reference: Autoimmun Rev. 2021 Sep;20(9):102893. doi: 10.1016/j.autrev.2021.102893. Epub 2021 Jul 5.
Impact factor: 9.754
Publication type: Review in international publication
Authors: Dema, Maria, Eixarch, Herena, Villar, Luisa M, Montalban, Xavier, Espejo, Carmen et al.
DOI: 10.1016/j.autrev.2021.102893

Immunosuppressive drugs modes of action.

PMID: 34874841
Journal: Best Practice & Research Clinical Gastroenterology
Year: 2021
Reference: Best Pract Res Clin Gastroenterol. 2021 Oct-Dec;54-55:101757. doi: 10.1016/j.bpg.2021.101757. Epub 2021 Jun 16.
Impact factor: 3.043
Publication type: Review in international publication
Authors: Meneghini, Maria, Bestard, Oriol, Grinyo, Josep Maria et al.
DOI: 10.1016/j.bpg.2021.101757

Immunotherapy, cancer and PET.

PMID: 33674234
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2021 Mar-Apr;40(2):123-135. doi: 10.1016/j.remn.2021.02.001. Epub 2021 Mar 2.
Impact factor: 1.359
Publication type: Review in national publication
Authors: Simo-Perdigo, M, Vercher-Conejero, J L, Viteri, S, Garcia-Velloso, M J et al.
DOI: 10.1016/j.remn.2021.02.001

Immunotherapy-induced isolated ACTH deficiency in cancer therapy.

PMID: 34609950
Journal: ENDOCRINE-RELATED CANCER
Year: 2021
Reference: Endocr Relat Cancer. 2021 Oct 27;28(12):783-792. doi: 10.1530/ERC-21-0228.
Impact factor: 5.678
Publication type: Paper in international publication
Authors: Iglesias, Pedro, Peiro, Inmaculada, Biagetti, Betina, Paja Fano, Miguel, Cobo, Diana Ariadel, Garcia Gomez, Carlos, Mateu-Salat, Manuel, Genua, Idoia, Majem, Margarita, Riudavets, Mariona et al.
DOI: 10.1530/ERC-21-0228

Impact of baseline patient characteristics on dupilumab efficacy in type 2 asthma.

PMID: 34326187
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2021
Reference: Eur Respir J. 2021 Oct 7;58(4). pii: 13993003.04605-2020. doi: 10.1183/13993003.04605-2020. Print 2021 Oct.
Impact factor: 16.671
Publication type: Letter or abstract
Authors: Busse, William W, Paggiaro, Pierluigi, Munoz, Xavier, Casale, Thomas B, Castro, Mario, Canonica, G Walter, Douglass, Jo A, Tohda, Yuji, Daizadeh, Nadia, Ortiz, Benjamin et al.
DOI: 10.1183/13993003.04605-2020

Impact of Chemical Composition on the Nanostructure and Biological Activity of alpha-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment.

PMID: 33583172
Journal: ACS Applied Materials & Interfaces
Year: 2021
Reference: ACS Appl Mater Interfaces. 2021 Feb 24;13(7):7825-7838. doi: 10.1021/acsami.0c16871. Epub 2021 Feb 14.
Impact factor: 9.229
Publication type: Paper in international publication
Authors: Danino, Dganit, Pedersen, Jan Skov, Gonzalez-Mira, Elisabet, Abasolo, Ibane, Ventosa, Nora, Cordoba, Alba, Royo, Miriam, Sala, Santi, Veciana, Jaume, Tomsen-Melero, Judit et al.
DOI: 10.1021/acsami.0c16871

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