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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Efficacy and safety of lurbinectedin and doxorubicin in relapsed small cell lung cancer. Results from an expansion cohort of a phase I study.

PMID: 33704620
Journal: INVESTIGATIONAL NEW DRUGS
Year: 2021
Reference: Invest New Drugs. 2021 Oct;39(5):1275-1283. doi: 10.1007/s10637-020-01025-x. Epub 2021 Mar 11.
Impact factor:
Publication type: Paper in international publication
Authors: Brana, Irene; Calvo, Emiliano; Cullell-Young, Martin; de Miguel, Maria; Doger, Bernard; Flynn, Michael; Forster, Martin; Kahatt, Carmen; Lopez-Criado, Maria Pilar; Lopez-Vilarino, Jose Antonio et al.
DOI: 10.1007/s10637-020-01025-x

Efficacy and safety of once-daily single-inhaler triple therapy in patients with inadequately controlled asthma: the CAPTAIN trial.

PMID: 34295395
Journal: Breathe (Sheffield, England)
Year: 2021
Reference: Breathe (Sheff). 2021 Mar;17(1):200279. doi: 10.1183/20734735.0279-2020.
Impact factor: 0
Publication type: Letter or abstract
Authors: Pilia, Maria Florencia, Ojanguren, Inigo et al.
DOI: 10.1183/20734735.0279-2020

Efficacy and safety of once-daily single-inhaler triple therapy in patients with inadequately controlled asthma: the CAPTAIN trial.

PMID: 34295395
Journal: Breathe (Sheffield, England)
Year: 2021
Reference: Breathe (Sheff). 2021 Mar;17(1):200279. doi: 10.1183/20734735.0279-2020.
Impact factor:
Publication type: Letter or abstract
Authors: Ojanguren, Inigo; Pilia, Maria Florencia et al.
DOI: 10.1183/20734735.0279-2020

Efficacy and safety of opioid therapy guided by pharmacogenetics: a systematic review.

PMID: 34013775
Journal: PHARMACOGENOMICS
Year: 2021
Reference: Pharmacogenomics. 2021 Jun;22(9):573-586. doi: 10.2217/pgs-2021-0021. Epub 2021 May 20.
Impact factor: 2.533
Publication type: Review in international publication
Authors: Rodriguez Cairoli, Federico, Appiani, Francisco, Sambade, Juan Manuel, Comande, Daniel, Camacho Arteaga, Lina, Ciapponi, Agustin et al.
DOI: 10.2217/pgs-2021-0021

Efficacy and safety of opioid therapy guided by pharmacogenetics: a systematic review.

PMID: 34013775
Journal: PHARMACOGENOMICS
Year: 2021
Reference: Pharmacogenomics. 2021 Jun;22(9):573-586. doi: 10.2217/pgs-2021-0021. Epub 2021 May 20.
Impact factor:
Publication type: Review in international publication
Authors: Appiani, Francisco; Camacho Arteaga, Lina; Camacho Arteaga, Lina; Ciapponi, Agustin; Comande, Daniel; Rodriguez Cairoli, Federico; Sambade, Juan Manuel et al.
DOI: 10.2217/pgs-2021-0021

Efficacy and Safety of PCSK9 Inhibitors in Hypercholesterolemia Associated With Refractory Nephrotic Syndrome.

PMID: 33426389
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Jatem, Elias, Lima, Joan, Montoro, Bruno, Torres-Bondia, Francisco, Segarra, Alfons et al.
DOI: 10.1016/j.ekir.2020.09.046

Efficacy and Safety of PCSK9 Inhibitors in Hypercholesterolemia Associated With Refractory Nephrotic Syndrome.

PMID: 33426389
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Jatem, Elias; Lima, Joan; Montoro, Bruno; Segarra, Alfons; Torres-Bondia, Francisco et al.
DOI: 10.1016/j.ekir.2020.09.046

Efficacy and safety of pembrolizumab in patients with advanced mesothelioma in the open-label, single-arm, phase 2 KEYNOTE-158 study.

PMID: 33836153
Journal: Lancet Respiratory Medicine
Year: 2021
Reference: Lancet Respir Med. 2021 Jun;9(6):613-621. doi: 10.1016/S2213-2600(20)30515-4. Epub 2021 Apr 6.
Impact factor: 30.7
Publication type: Paper in international publication
Authors: Yap, Timothy A, Nakagawa, Kazuhiko, Fujimoto, Nobukazu, Kuribayashi, Kozo, Guren, Tormod Kyrre, Shapira-Frommer, Ronnie, Gao, Bo, Kao, Steven, Matos, Ignacio, Planchard, David et al.
DOI: 10.1016/S2213-2600(20)30515-4

Efficacy and safety of pembrolizumab in patients with advanced mesothelioma in the open-label, single-arm, phase 2 KEYNOTE-158 study.

PMID: 33836153
Journal: Lancet Respiratory Medicine
Year: 2021
Reference: Lancet Respir Med. 2021 Jun;9(6):613-621. doi: 10.1016/S2213-2600(20)30515-4. Epub 2021 Apr 6.
Impact factor:
Publication type: Paper in international publication
Authors: Calabro, Luana; Chatterjee, Arkendu; Fujimoto, Nobukazu; Gao, Bo; Guren, Tormod Kyrre; Jin, Fan; Kao, Steven; Kindler, Hedy L; Kuribayashi, Kozo; Matos, Ignacio et al.
DOI: 10.1016/S2213-2600(20)30515-4

Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS).

PMID: 34030643
Journal: BMC CANCER
Year: 2021
Reference: BMC Cancer. 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z.
Impact factor: 4.43
Publication type: Paper in international publication
Authors: Grivas, P, Loriot, Y, Morales-Barrera, R, Teo, M Y, Zakharia, Y, Feyerabend, S, Vogelzang, N J, Grande, E, Adra, N, Alva, A et al.
DOI: 10.1186/s12885-021-08085-z

Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS).

PMID: 34030643
Journal: BMC CANCER
Year: 2021
Reference: BMC Cancer. 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z.
Impact factor:
Publication type: Paper in international publication
Authors: Adra, N; Alva, A; Chowdhury, S; Dusek, R L; Feyerabend, S; Grande, E; Grivas, P; Gupta, S; Josephs, D H; Loehr, A et al.
DOI: 10.1186/s12885-021-08085-z

Efficacy and safety of switching to dolutegravir plus lamivudine versus continuing triple antiretroviral therapy in virologically suppressed adults with HIV at 48 weeks (DOLAM): a randomised non-inferiority trial.

PMID: 34358497
Journal: Lancet HIV
Year: 2021
Reference: Lancet HIV. 2021 Aug;8(8):e463-e473. doi: 10.1016/S2352-3018(21)00100-4.
Impact factor: 12.767
Publication type: Paper in international publication
Authors: Rojas, Jhon, de Lazzari, Elisa, Negredo, Eugenia, Domingo, Pere, Tiraboschi, Juan, Ribera, Esteve, Abdulghani, Nadia, Podzamczer, Daniel, Gutierrez, Maria M, Paredes, Roger et al.
DOI: 10.1016/S2352-3018(21)00100-4

Efficacy and safety of switching to dolutegravir plus lamivudine versus continuing triple antiretroviral therapy in virologically suppressed adults with HIV at 48 weeks (DOLAM): a randomised non-inferiority trial.

PMID: 34358497
Journal: Lancet HIV
Year: 2021
Reference: Lancet HIV. 2021 Aug;8(8):e463-e473. doi: 10.1016/S2352-3018(21)00100-4.
Impact factor:
Publication type: Paper in international publication
Authors: Abdulghani, Nadia; Blanco, Jose L; Clotet, Bonaventura; de Lazzari, Elisa; Domingo, Pere; Gatell, Jose M; Gutierrez, Maria M; Martinez, Esteban; Mateo, Maria G; Negredo, Eugenia et al.
DOI: 10.1016/S2352-3018(21)00100-4

Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke: An Exploratory Analysis of the THALES Randomized Clinical Trial.

PMID: 34244703
Journal: JAMA Neurology
Year: 2021
Reference: JAMA Neurol. 2021 Sep 1;78(9):1091-1098. doi: 10.1001/jamaneurol.2021.2440.
Impact factor: 18.302
Publication type: Paper in international publication
Authors: Hu, Bo, Gomez Schneider, Maia, Pigretti, Santiago, Lipovestky, Fernando, Zurru, Maria C, Davis, Stephen, Wong, Andrew, Wijeratne, Tissa, Sabet, Arman, Lee, Andrew et al.
DOI: 10.1001/jamaneurol.2021.2440

Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke: An Exploratory Analysis of the THALES Randomized Clinical Trial.

PMID: 34244703
Journal: JAMA Neurology
Year: 2021
Reference: JAMA Neurol. 2021 Sep 1;78(9):1091-1098. doi: 10.1001/jamaneurol.2021.2440.
Impact factor:
Publication type: Paper in international publication
Authors: Adami, Alessandro; Adrasetty, Gopal R; Agnelli, Giancarlo; Ahmed, Niaz; Akhmadeeva, Leila; Aksentiev, Sergei; Al-Senani, Fahmi; Alamowitch, Sonia; Alghamdi, Saeed; Alhussein, Fawaz et al.
DOI: 10.1001/jamaneurol.2021.2440

Efficacy and safety of TOBI Podhaler(R) in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study.

PMID: 32855225
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2021
Reference: Eur Respir J. 2021 Jan 5;57(1). pii: 13993003.01451-2020. doi: 10.1183/13993003.01451-2020. Print 2021 Jan.
Impact factor: 16.671
Publication type: Paper in international publication
Authors: Loebinger, Michael R, Polverino, Eva, Chalmers, James D, Tiddens, Harm A W M, Goossens, Herman, Tunney, Michael, Ringhausen, Felix C, Hill, Adam T, Pathan, Rashidkhan, Angyalosi, Gerhild et al.
DOI: 10.1183/13993003.01451-2020

Efficacy and safety of TOBI Podhaler(R) in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study.

PMID: 32855225
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2021
Reference: Eur Respir J. 2021 Jan 5;57(1). pii: 13993003.01451-2020. doi: 10.1183/13993003.01451-2020. Print 2021 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Angyalosi, Gerhild; Blasi, Francesco; Chalmers, James D; Elborn, Stuart J; Goossens, Herman; Haworth, Charles S; Hill, Adam T; Loebinger, Michael R; Pathan, Rashidkhan; Polverino, Eva et al.
DOI: 10.1183/13993003.01451-2020

Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery.

PMID: 34857831
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Dec 2;11(1):23358. doi: 10.1038/s41598-021-02694-1.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Kagiava, A, Richter, J, Tryfonos, C, Leal-Julia, M, Sargiannidou, I, Christodoulou, C, Bosch, A, Kleopa, K A et al.
DOI: 10.1038/s41598-021-02694-1

Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery.

PMID: 34857831
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Dec 2;11(1):23358. doi: 10.1038/s41598-021-02694-1.
Impact factor:
Publication type: Paper in international publication
Authors: Bosch, A; Christodoulou, C; Kagiava, A; Kleopa, K A; Leal-Julia, M; Richter, J; Sargiannidou, I; Tryfonos, C et al.
DOI: 10.1038/s41598-021-02694-1

Efficacy of chemotherapy for malignant pleural mesothelioma according to histology in a real-world cohort.

PMID: 34725384
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Nov 1;11(1):21357. doi: 10.1038/s41598-021-00831-4.
Impact factor:
Publication type: Paper in international publication
Authors: Amat, Ramon; Assaf, Juan-David; Callejo, Ana; Carbonell, Caterina; Cedres, Susana; Dienstmann, Rodrigo; Felip, Enriqueta; Frigola, Joan; Iranzo, Patricia; Marmolejo, David et al.
DOI: 10.1038/s41598-021-00831-4

Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.

PMID: 33480963
Journal: JAMA Oncology
Year: 2021
Reference: JAMA Oncol. 2021 Apr 1;7(4):573-584. doi: 10.1001/jamaoncol.2020.7932.
Impact factor: 31.777
Publication type: Paper in international publication
Authors: Im, Seock-Ah, Rugo, Hope S, Gradishar, William J, Rock, Edwin P, Hong, Shengyan, Koenig, Scott, Curigliano, Giuseppe, Musolino, Antonino, Pegram, Mark D, Wright, Gail S et al.
DOI: 10.1001/jamaoncol.2020.7932

Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.

PMID: 33480963
Journal: JAMA Oncology
Year: 2021
Reference: JAMA Oncol. 2021 Apr 1;7(4):573-584. doi: 10.1001/jamaoncol.2020.7932.
Impact factor:
Publication type: Paper in international publication
Authors: Bonvini, Ezio; Brown-Glaberman, Ursa; Cardoso, Fatima; Cortes, Javier; Curigliano, Giuseppe; de Boer, Maaike; De Laurentiis, Michelino; Edlich, Sutton; Escriva-de-Romani, Santiago; Fasching, Peter A et al.
DOI: 10.1001/jamaoncol.2020.7932

Efficacy of naloxegol on symptoms and quality of life related to opioid-induced constipation in patients with cancer: a 3-month follow-up analysis.

PMID: 32376758
Journal: BMJ Supportive & Palliative Care
Year: 2021
Reference: BMJ Support Palliat Care. 2021 Mar;11(1):25-31. doi: 10.1136/bmjspcare-2020-002249. Epub 2020 May 6.
Impact factor: 3.568
Publication type: Paper in international publication
Authors: Garcia Navalon, Francisco, Cobo Dols, Manuel, Beato Zambrano, Carmen, Cabezon Gutierrez, Luis, Chicas Sett, Rodolfo, Blancas Lopez-Barajas, Maria Isabel, Togores Torres, Pilar, Delgado Mingorance, Ignacio, Giraldo Marin, Alexandra, Libran Oriol, Anna et al.
DOI: 10.1136/bmjspcare-2020-002249

Efficacy of naloxegol on symptoms and quality of life related to opioid-induced constipation in patients with cancer: a 3-month follow-up analysis.

PMID: 32376758
Journal: BMJ Supportive & Palliative Care
Year: 2021
Reference: BMJ Support Palliat Care. 2021 Mar;11(1):25-31. doi: 10.1136/bmjspcare-2020-002249. Epub 2020 May 6.
Impact factor:
Publication type: Paper in international publication
Authors: Beato Zambrano, Carmen; Blancas Lopez-Barajas, Maria Isabel; Cabezon Gutierrez, Luis; Chicas Sett, Rodolfo; Cobo Dols, Manuel; Delgado Mingorance, Ignacio; Firvida Perez, Jose Luis; Garcia Navalon, Francisco; Giraldo Marin, Alexandra; Higuera Gomez, Oliver et al.
DOI: 10.1136/bmjspcare-2020-002249