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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Trends in endpoint selection and result interpretation in advanced non-small cell lung cancer clinical trials published between 2000 and 2012: A retrospective cohort study.

PMID: 30868737
Journal: Thoracic Cancer
Year: 2019
Reference: Thorac Cancer. 2019 Apr;10(4):904-908. doi: 10.1111/1759-7714.13024. Epub 2019 Mar 13.
Impact factor: 2.524
Publication type: Paper in international publication
Authors: Calleja-Hernandez, Miguel Angel, Balbino, Jaime Espin, Cabeza-Barrera, Jose, Exposito-Hernandez, Jose, Fernandez-Lopez, Cristina et al.
DOI: 10.1111/1759-7714.13024

Trends in healthcare resource use and expenditure before and after ischaemic stroke. A population-based study.

PMID: 30902459
Journal: Neurologia (Barcelona, Spain)
Year: 2019
Reference: Neurologia (Engl Ed). 2019 Mar 19. pii: S0213-4853(19)30005-2. doi: 10.1016/j.nrl.2018.11.002.
Impact factor: 0
Publication type: Paper in national publication
Authors: Ribera, A, Vela, E, Garcia-Altes, A, Cleries, M, Abilleira, S et al.
DOI: 10.1016/j.nrl.2018.11.002

Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry.

PMID: 31218003
Journal: Open heart
Year: 2019
Reference: Open Heart. 2019 May 21;6(1):e001008. doi: 10.1136/openhrt-2019-001008. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Frank, Derk, Kennon, Simon, Bonaros, Nikolaos, Romano, Mauro, Lefevre, Thierry, Di Mario, Carlo, Stefano, Pierluigi, Ribichini, Flavio Luciano, Himbert, Dominique, Urena-Alcazar, Marina et al.
DOI: 10.1136/openhrt-2019-001008

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.

PMID: 31028084
Journal: EMBO JOURNAL
Year: 2019
Reference: EMBO J. 2019 Jun 3;38(11). pii: embj.2018100299. doi: 10.15252/embj.2018100299. Epub 2019 Apr 26.
Impact factor: 11.227
Publication type: Paper in international publication
Authors: Guo, Manman, Hartlova, Anetta, Gierlinski, Marek, Prescott, Alan, Castellvi, Josep, Losa, Javier Hernandez, Petersen, Sine K, Wenzel, Ulf A, Dill, Brian D, Emmerich, Christoph H et al.
DOI: 10.15252/embj.2018100299

Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression.

PMID: 31842958
Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Year: 2019
Reference: J Exp Clin Cancer Res. 2019 Dec 16;38(1):492. doi: 10.1186/s13046-019-1497-0.
Impact factor: 5.646
Publication type: Paper in international publication
Authors: Troiani, T, Morgillo, F, Napolitano, S, Matrone, N, Muddassir, A L, Martini, G, Sorokin, A, De Falco, V, Giunta, E F, Ciardiello, D et al.
DOI: 10.1186/s13046-019-1497-0

Triple-drug chemotherapy regimens in combination with an anti-EGFR agent in metastatic colorectal cancer - prospects from phase II clinical trials.

PMID: 30905200
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS
Year: 2019
Reference: Expert Opin Investig Drugs. 2019 May;28(5):463-471. doi: 10.1080/13543784.2019.1599860. Epub 2019 Apr 20.
Impact factor: 4.031
Publication type: Paper in international publication
Authors: Matos, Ignacio, Noguerido, Alba, Ros, Javier, Mulet, Nuria, Argiles, Guillem, Elez, Elena, Tabernero, Josep et al.
DOI: 10.1080/13543784.2019.1599860

Tuberculosis incidence among infected contacts detected through contact tracing of smear-positive patients.

PMID: 30986227
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Apr 15;14(4):e0215322. doi: 10.1371/journal.pone.0215322. eCollection 2019.
Impact factor: 2.776
Publication type: Paper in international publication
Authors: Martin-Sanchez, Mario, Brugueras, Silvia, de Andres, Anna, Simon, Pere, Gorrindo, Pilar, Ros, Miriam, Masdeu, Eva, Millet, Joan-Pau, Cayla, Joan A, Orcau, Angels et al.
DOI: 10.1371/journal.pone.0215322

Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients.

PMID: 31614664
Journal: Cancers
Year: 2019
Reference: Cancers (Basel). 2019 Oct 11;11(10). pii: cancers11101540. doi: 10.3390/cancers11101540.
Impact factor: 6.162
Publication type: Paper in international publication
Authors: Martinez-Balibrea, Eva, Ruiz de Porras, Vicenc, Bystrup, Sara, Musulen, Eva, Palomero, Luis, Alonso, Maria Henar, Nieto, Rocio, Arango, Diego, Moreno, Victor, Queralt, Cristina et al.
DOI: 10.3390/cancers11101540

Tumor thrombosis in right inferior pulmonary vein due to chondrosarcoma metastasis and systemic embolism.

PMID: 30871821
Journal: MEDICINA CLINICA
Year: 2019
Reference: Med Clin (Barc). 2019 Sep 27;153(6):e29. doi: 10.1016/j.medcli.2019.01.024. Epub 2019 Mar 11.
Impact factor: 1.277
Publication type: Paper in national publication
Authors: Persiva, Oscar, Pallisa, Esther, Sanchez, Ana Lucia, Varona Porres, Diego et al.
DOI: 10.1016/j.medcli.2019.01.024

Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy.

PMID: 29788230
Journal: JNCI-Journal of the National Cancer Institute
Year: 2019
Reference: J Natl Cancer Inst. 2019 Jan 1;111(1):69-77. doi: 10.1093/jnci/djy076.
Impact factor: 10.211
Publication type: Paper in international publication
Authors: Ignatiadis, Michail, Van den Eynden, Gert, Roberto, Salgado, Fornili, Marco, Bareche, Yacine, Desmedt, Christine, Rothe, Francoise, Maetens, Marion, Venet, David, Holgado, Esther et al.
DOI: 10.1093/jnci/djy076

Tumour Treating Fields in combination with pemetrexed and cisplatin or carboplatin as first-line treatment for unresectable malignant pleural mesothelioma (STELLAR): a multicentre, single-arm phase 2 trial.

PMID: 31628016
Journal: LANCET ONCOLOGY
Year: 2019
Reference: Lancet Oncol. 2019 Dec;20(12):1702-1709. doi: 10.1016/S1470-2045(19)30532-7. Epub 2019 Oct 15.
Impact factor: 35.386
Publication type: Paper in international publication
Authors: Ceresoli, Giovanni L, Aerts, Joachim G, Dziadziuszko, Rafal, Ramlau, Rodryg, Cedres, Susana, Mencoboni, Manlio, Planchard, David, Chella, Antonio, Crino, Lucio, Krzakowski, Maciej et al.
DOI: 10.1016/S1470-2045(19)30532-7

Tweets of the month.

PMID: 31747066
Journal: BRITISH JOURNAL OF SURGERY
Year: 2019
Reference: Br J Surg. 2019 Dec;106(13):1856-1857. doi: 10.1002/bjs.11439.
Impact factor: 5.586
Publication type: Letter or abstract
Authors: Pellino, G et al.
DOI: 10.1002/bjs.11439

Twenty four years of oral and maxillofacial surgery malpractice claims in Spain: patient safety lessons to learn.

PMID: 31037563
Journal: Oral and maxillofacial surgery
Year: 2019
Reference: Oral Maxillofac Surg. 2019 Jun;23(2):187-192. doi: 10.1007/s10006-019-00756-3. Epub 2019 Apr 29.
Impact factor: 0
Publication type: Paper in international publication
Authors: Bordonaba-Leiva, Sergio, Gomez-Duran, Esperanza L, Balibrea, Jose M, Benet-Trave, Josep, Martin-Fumado, Carles, Bescos Atin, Coro, Mareque-Bueno, Javier, Arimany-Manso, Josep et al.
DOI: 10.1007/s10006-019-00756-3

Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.

PMID: 30234793
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2019
Reference: Pediatr Infect Dis J. 2019 Jan;38(1):16-21. doi: 10.1097/INF.0000000000002188.
Impact factor: 2.317
Publication type: Paper in international publication
Authors: Valli, Maria Beatrice, Rainetova, Petra, Midgley, Sofie, Fischer, Thea Kolsen, Simonlatser, Grethel, Savolainen-Kopra, Carita, Lina, Bruno, Schuffenecker, Isabelle, Kossorotoff, Manoelle, Antona, Denise et al.
DOI: 10.1097/INF.0000000000002188

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases.

PMID: 31645906
Journal: Oncotarget
Year: 2019
Reference: Oncotarget. 2019 Oct 8;10(56):5871-5887. doi: 10.18632/oncotarget.27232. eCollection 2019 Oct 8.
Impact factor: 0
Publication type: Paper in international publication
Authors: Alvarez-Palomo, Belen, Barrot-Feixat, Carme, Sarret, Helena, Requena, Jordi, Pau, Montserrat, Vidal-Taboada, Jose-Manuel, Oliva, Rafael, Ballesca, Josep-Lluis, Edel, Michael J, Mezquita-Pla, Jovita et al.
DOI: 10.18632/oncotarget.27232

Type IIIB Endoleak 19 Years After Thoracic Endovascular Aneurysm Repair.

PMID: 30172664
Journal: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
Year: 2019
Reference: Eur J Vasc Endovasc Surg. 2019 Jan;57(1):101. doi: 10.1016/j.ejvs.2018.07.039. Epub 2018 Aug 29.
Impact factor: 3.642
Publication type: Paper in international publication
Authors: Sala, Daniel G, Valenzuela, Valentin F et al.
DOI: 10.1016/j.ejvs.2018.07.039

Ultra-selection of metastatic colorectal cancer patients using Next Generation Sequencing to improve clinical efficacy of anti-EGFR therapy.

PMID: 30689692
Journal: ANNALS OF ONCOLOGY
Year: 2019
Reference: Ann Oncol. 2019 Mar 1;30(3):439-446. doi: 10.1093/annonc/mdz005.
Impact factor: 14.196
Publication type: Paper in international publication
Authors: Santos Vivas, C, Garcia-Alfonso, P, Carrato, A, Cano, M T, Garcia-Carbonero, R, Elez, E, Losa, F, Massuti, B, Valladares-Ayerbes, M, Vieitez, J M et al.
DOI: 10.1093/annonc/mdz005

Uncommon burn complication: skin nocardiosis.

PMID: 32431579
Journal: Annals of burns and fire disasters
Year: 2019
Reference: Ann Burns Fire Disasters. 2019 Dec 31;32(4):289-293.
Impact factor: 0
Publication type: Paper in international publication
Authors: Cases-Perera, O, Aguilera-Saez, J, Monte, A, Rivas-Nicolls, D, Andres-Collado, A, Lopez-Masramon, B M, Serracanta, J et al.
DOI:

Uncomplicated type A intramural hematoma: surgery or conservative approach?-surgery.

PMID: 31667153
Journal: Annals of Cardiothoracic Surgery
Year: 2019
Reference: Ann Cardiothorac Surg. 2019 Sep;8(5):556-557. doi: 10.21037/acs.2019.07.04.
Impact factor: 2.895
Publication type: Editorail in international publication
Authors: Maldonado, Giuliana, Moral, Sergio, Rodriguez-Palomares, Jose, Evangelista, Arturo et al.
DOI: 10.21037/acs.2019.07.04

Underdosing of Surfactant for Preterm Babies with Respiratory Distress Syndrome in Clinical Practice: A Retrospective Cohort Study.

PMID: 30414597
Journal: AMERICAN JOURNAL OF PERINATOLOGY
Year: 2019
Reference: Am J Perinatol. 2019 Jul;36(9):943-948. doi: 10.1055/s-0038-1675645. Epub 2018 Nov 10.
Impact factor: 1.581
Publication type: Paper in international publication
Authors: Baquedano, Irene, Sanchez, Ana, Ferreira, Erika, Fernandez, Patricia, Gonzalez, Rosa, Elorza, M Dolores, Serrano, Itziar, Fernandez, Cristina, Arruza, Luis, Rite, Segundo et al.
DOI: 10.1055/s-0038-1675645

Understanding the relation between Zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual participant data meta-analysis of longitudinal studies of pregnant women and their infants and children.

PMID: 31217315
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 Jun 18;9(6):e026092. doi: 10.1136/bmjopen-2018-026092.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Lan, Zhiyi, Sousa, Patricia, Soriano-Arandes, Antoni, Soria-Segarra, Carmen, Sanchez Clemente, Nuria, Rosenberger, Kerstin Daniela, Reveiz, Ludovic, Prata-Barbosa, Arnaldo, Pomar, Leo, Pela Rosado, Luiza Emylce et al.
DOI: 10.1136/bmjopen-2018-026092

Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain.

PMID: 31253111
Journal: BMC PUBLIC HEALTH
Year: 2019
Reference: BMC Public Health. 2019 Jun 28;19(1):840. doi: 10.1186/s12889-019-7225-z.
Impact factor: 2.567
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Faro, Monica, Zaragoza, Maria Cleofe, Aliste, Luisa, de Sevilla, Tomas Fernandez, Alegre, Jose et al.
DOI: 10.1186/s12889-019-7225-z

Unexpected Relevant Role of Gene Mosaicism in Primary Immunodeficiency Diseases.

PMID: 30273710
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2019
Reference: J Allergy Clin Immunol. 2019 Jan;143(1):359-368. doi: 10.1016/j.jaci.2018.09.009. Epub 2018 Sep 29.
Impact factor: 14.11
Publication type: Paper in international publication
Authors: Balderrama-Rodriguez, Angelica, Ramos, Eduardo, Modesto, Consuelo, Mesa-Del-Castillo, Pablo, Ortego-Centeno, Norberto, Clemente, Daniel, Souto, Alejandro, Palmou, Natalia, Remesal, Agustin, Leslie, Kieron S et al.
DOI: 10.1016/j.jaci.2018.09.009

Unilateral vs. Bilateral Lower Extremity Motor Deficit Following Complex Adult Spinal Deformity Surgery: Is there a Difference in Recovery Up to 2 Year F/U?

PMID: 30118851
Journal: Spine Journal
Year: 2019
Reference: Spine J. 2019 Mar;19(3):395-402. doi: 10.1016/j.spinee.2018.08.003. Epub 2018 Aug 14.
Impact factor: 3.196
Publication type: Paper in international publication
Authors: Tuchman, Alexander, Lenke, Lawrence G, Cerpa, Meghan, Fehlings, Michael G, Lewis, Stephen J, Shaffrey, Christopher I, Cheung, Kenneth M C, Carreon, Leah Yacat, Dekutoski, Mark B, Schwab, Frank J et al.
DOI: 10.1016/j.spinee.2018.08.003

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