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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

8-year survival in chronic hepatitis B patients under long-term entecavir or tenofovir therapy is similar to the general population.

PMID: 29427727
Journal: JOURNAL OF HEPATOLOGY
Year: 2018
Reference: J Hepatol. 2018 Jun;68(6):1129-1136. doi: 10.1016/j.jhep.2018.01.031. Epub 2018 Feb 8.
Impact factor: 14.911
Publication type: Paper in international publication
Authors: Papatheodoridis, George V, Sypsa, Vana, Dalekos, George, Yurdaydin, Cihan, Van Boemmel, Florian, Buti, Maria, Goulis, John, Luis Calleja, Jose, Chi, Heng, Manolakopoulos, Spilios et al.
DOI: 10.1016/j.jhep.2018.01.031

96weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection.

PMID: 29756595
Journal: JOURNAL OF HEPATOLOGY
Year: 2018
Reference: J Hepatol. 2018 Apr;68(4):672-681. doi: 10.1016/j.jhep.2017.11.039. Epub 2018 Jan 17.
Impact factor: 14.911
Publication type: Paper in international publication
Authors: Agarwal, Kosh, Brunetto, Maurizia, Seto, Wai Kay, Lim, Young-Suk, Fung, Scott, Marcellin, Patrick, Ahn, Sang Hoon, Izumi, Namiki, Chuang, Wan-Long, Bae, Ho et al.
DOI: 10.1016/j.jhep.2017.11.039

A case of respiratory toxigenic diphtheria: contact tracing results and considerations following a 30-year disease-free interval, Catalonia, Spain, 2015.

PMID: 29616610
Journal: Eurosurveillance
Year: 2018
Reference: Euro Surveill. 2018 Mar;23(13). doi: 10.2807/1560-7917.ES.2018.23.13.17-00183.
Impact factor: 7.127
Publication type: Paper in international publication
Authors: Pumarola, Tomas, Follia, Nuria, Jane, Mireia, Vidal, Maria Jose, Camps, Neus, Campins, Magda, Martinez, Ana, Balcells, Joan, Martin-Gomez, Maria Teresa, Bassets, Gloria et al.
DOI: 10.2807/1560-7917.ES.2018.23.13.17-00183

A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse.

PMID: 29912942
Journal: PLoS Genetics
Year: 2018
Reference: PLoS Genet. 2018 Jun 18;14(6):e1007432. doi: 10.1371/journal.pgen.1007432. eCollection 2018 Jun.
Impact factor: 5.54
Publication type: Paper in international publication
Authors: Ros, Oriol, Barrecheguren, Pablo Jose, Cotrufo, Tiziana, Schaettin, Martina, Rosello-Busquets, Cristina, Vilchez-Acosta, Alba, Hernaiz-Llorens, Marc, Martinez-Marmol, Ramon, Stoeckli, Esther T, Araujo, Sofia J et al.
DOI: 10.1371/journal.pgen.1007432

A critical appraisal of the quality of low back pain practice guidelines using the AGREE II tool and comparison with previous evaluations: a EuroAIM initiative.

PMID: 30220040
Journal: EUROPEAN SPINE JOURNAL
Year: 2018
Reference: Eur Spine J. 2018 Nov;27(11):2781-2790. doi: 10.1007/s00586-018-5763-1. Epub 2018 Sep 15.
Impact factor: 2.634
Publication type: Review in international publication
Authors: Doniselli, Fabio Martino, Zanardo, Moreno, Manfre, Luigi, Papini, Giacomo Davide Edoardo, Rovira, Alex, Sardanelli, Francesco, Sconfienza, Luca Maria, Arana, Estanislao et al.
DOI: 10.1007/s00586-018-5763-1

A European, Observational Study of Endocrine Therapy Administration in Patients With an Initial Diagnosis of Hormone Receptor-Positive Advanced Breast Cancer.

PMID: 29275865
Journal: Clinical Breast Cancer
Year: 2018
Reference: Clin Breast Cancer. 2018 Aug;18(4):e613-e619. doi: 10.1016/j.clbc.2017.11.019. Epub 2017 Nov 29.
Impact factor: 2.703
Publication type: Paper in international publication
Authors: Bastiaannet, Esther, Charman, Jackie, Johannesen, Tom Borge, Schrodi, Simone, Siesling, Sabine, van Eycken, Liesbet, Walsh, Paul M, Audisio, Riccardo A, Boelens, Petra G, Rubio, Isabel T et al.
DOI: 10.1016/j.clbc.2017.11.019

A Five-year Prospective Multi-center Evaluation of Influenza Infection in Transplant Recipients.

PMID: 29635437
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2018
Reference: Clin Infect Dis. 2018 Oct 15;67(9):1322-1329. doi: 10.1093/cid/ciy294.
Impact factor: 9.117
Publication type: Paper in international publication
Authors: Montejo, Miguel, Lopez-Medrano, Francisco, Farinas, Maria Carmen, Gavalda, Joan, Moreno, Asuncion, Levi, Marilyn, Fortun, Jesus, Torre-Cisneros, Julian, Englund, Janet A, Natori, Yoichiro et al.
DOI: 10.1093/cid/ciy294

A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).

PMID: 30137196
Journal: ANNALS OF ONCOLOGY
Year: 2018
Reference: Ann Oncol. 2018 Sep 1;29(9):1895-1902. doi: 10.1093/annonc/mdy263.
Impact factor: 13.926
Publication type: Paper in international publication
Authors: Mateo, J, Chakravarty, D, Dienstmann, R, Jezdic, S, Gonzalez-Perez, A, Lopez-Bigas, N, Ng, C K Y, Bedard, P L, Tortora, G, Douillard, J-Y et al.
DOI: 10.1093/annonc/mdy263

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.

PMID: 29325848
Journal: BIOLOGICAL PSYCHIATRY
Year: 2018
Reference: Biol Psychiatry. 2018 Jun 15;83(12):1044-1053. doi: 10.1016/j.biopsych.2017.11.026. Epub 2017 Dec 2.
Impact factor: 11.982
Publication type: Paper in international publication
Authors: Hervas, Amaia, Mors, Ole, Nordentoft, Merete, Hougaard, David M, Bybjerg-Grauholm, Jonas, Wray, Naomi R, Franke, Barbara, Faraone, Stephen V, O'Donovan, Michael C, Thapar, Anita et al.
DOI: 10.1016/j.biopsych.2017.11.026

A homozygous loss-of-function mutation in PDE2A associated to early-onset hereditary chorea.

PMID: 29392776
Journal: MOVEMENT DISORDERS
Year: 2018
Reference: Mov Disord. 2018 Mar;33(3):482-488. doi: 10.1002/mds.27286. Epub 2018 Feb 2.
Impact factor: 8.324
Publication type: Paper in international publication
Authors: Bettencourt, Conceicao, Mencacci, Niccolo E, Klein, Christine, Kelly, Michy P, Davies, Ceri H, Kimura, Haruhide, Macaya, Alfons, Houlden, Henry, Vandrovcova, Jana, Efthymiou, Stephanie et al.
DOI: 10.1002/mds.27286

A kidney-disease gene panel allows a comprehensive genetic diagnosis of cystic and glomerular inherited kidney diseases.

PMID: 29801666
Journal: KIDNEY INTERNATIONAL
Year: 2018
Reference: Kidney Int. 2018 Aug;94(2):363-371. doi: 10.1016/j.kint.2018.02.027. Epub 2018 May 22.
Impact factor: 8.429
Publication type: Paper in international publication
Authors: Bullich, Gemma, Domingo-Gallego, Andrea, Vargas, Ivan, Ruiz, Patricia, Lorente-Grandoso, Laura, Furlano, Monica, Fraga, Gloria, Madrid, Alvaro, Ariceta, Gema, Borregan, Mar et al.
DOI: 10.1016/j.kint.2018.02.027

A Kinematic Sensor and Algorithm to Detect Motor Fluctuations in Parkinson Disease: Validation Study Under Real Conditions of Use.

PMID: 29695377
Journal: JMIR rehabilitation and assistive technologies
Year: 2018
Reference: JMIR Rehabil Assist Technol. 2018 Apr 25;5(1):e8. doi: 10.2196/rehab.8335.
Impact factor: 0
Publication type: Paper in international publication
Authors: Rodriguez-Molinero, Alejandro, Sama, Albert, de Mingo, Eva, Rodriguez-Martin, Daniel, Hernandez-Vara, Jorge, Bayes, Angels, Moral, Alfons, Alvarez, Ramiro, Perez-Martinez, David A, Catala, Andreu et al.
DOI: 10.2196/rehab.8335

A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor beta agonists toward tumor burden.

PMID: 29164964
Journal: LEUKEMIA & LYMPHOMA
Year: 2018
Reference: Leuk Lymphoma. 2018 Jul;59(7):1726-1729. doi: 10.1080/10428194.2017.1399313. Epub 2017 Nov 22.
Impact factor: 2.644
Publication type: Letter whit IF
Authors: Body, Simon, Esteve-Arenys, Anna, Recasens-Zorzo, Clara, Troussard, Xavier, Roue, Gael, Sola, Brigitte et al.
DOI: 10.1080/10428194.2017.1399313

A new approach to obtain pure and active proteins from Lactococcus lactis protein aggregates.

PMID: 30224788
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Sep 17;8(1):13917. doi: 10.1038/s41598-018-32213-8.
Impact factor: 4.122
Publication type: Paper in international publication
Authors: Gifre-Renom, L, Cano-Garrido, O, Fabregas, F, Roca-Pinilla, R, Seras-Franzoso, J, Ferrer-Miralles, N, Villaverde, A, Bach, A, Devant, M, Aris, A et al.
DOI: 10.1038/s41598-018-32213-8

A novel EPM2A mutation yields a slow progression form of Lafora disease.

PMID: 30041081
Journal: EPILEPSY RESEARCH
Year: 2018
Reference: Epilepsy Res. 2018 Sep;145:169-177. doi: 10.1016/j.eplepsyres.2018.07.003. Epub 2018 Jul 21.
Impact factor: 2.491
Publication type: Paper in international publication
Authors: Garcia-Gimeno, Maria Adelaida, Rodilla-Ramirez, Pilar Natalia, Viana, Rosa, Salas-Puig, Xavier, Brewer, M Kathryn, Gentry, Matthew S, Sanz, Pascual et al.
DOI: 10.1016/j.eplepsyres.2018.07.003

A Novel Heterozygous Intronic Mutation in the FBN1 Gene Contributes to FBN1 RNA Missplicing Events in the Marfan Syndrome.

PMID: 30003093
Journal: Biomed Research International
Year: 2018
Reference: Biomed Res Int. 2018 May 29;2018:3536495. doi: 10.1155/2018/3536495. eCollection 2018.
Impact factor: 2.583
Publication type: Paper in international publication
Authors: Torrado, Mario, Maneiro, Emilia, Trujillo-Quintero, Juan Pablo, Evangelista, Arturo, Mikhailov, Alexander T, Monserrat, Lorenzo et al.
DOI: 10.1155/2018/3536495

A novel marker for identifying and studying the membranes, barriers, and compartments surrounding peripheral nerves microscopically.

PMID: 30113091
Journal: CLINICAL ANATOMY
Year: 2018
Reference: Clin Anat. 2018 Oct;31(7):1050-1057. doi: 10.1002/ca.23253. Epub 2018 Oct 26.
Impact factor: 1.908
Publication type: Paper in international publication
Authors: Reina, Miguel A, Boezaart, Andre P, Sala-Blanch, Xavier, Monzo, Enrique, Shane Tubbs, R, Server, Anna, Bigeleisen, Paul et al.
DOI: 10.1002/ca.23253

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations.

PMID: 29666300
Journal: CLINICAL CANCER RESEARCH
Year: 2018
Reference: Clin Cancer Res. 2018 Aug 1;24(15):3717-3728. doi: 10.1158/1078-0432.CCR-17-3509. Epub 2018 Apr 17.
Impact factor: 10.199
Publication type: Paper in international publication
Authors: Tamborero, David, Rubio-Perez, Carlota, Muinos, Ferran, Sabarinathan, Radhakrishnan, Piulats, Josep Maria, Muntasell, Aura, Dienstmann, Rodrigo, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel et al.
DOI: 10.1158/1078-0432.CCR-17-3509

A Phase 2 multicenter study of the anti-CD19 antibody drug conjugate coltuximab ravtansine (SAR3419) in patients with relapsed or refractory diffuse large B-cell lymphoma previously treated with rituximab-based immunotherapy.

PMID: 29748443
Journal: HAEMATOLOGICA
Year: 2018
Reference: Haematologica. 2018 Aug;103(8):1351-1358. doi: 10.3324/haematol.2017.168401. Epub 2018 May 10.
Impact factor: 9.09
Publication type: Paper in international publication
Authors: Verhoef, Gregor, Dyer, Martin Js, Yehuda, Dina Ben, Patti, Caterina, Canales, Miguel, Lopez, Andres, Awan, Farrukh T, Montgomery, Paul G, Janikova, Andrea, Barbui, Anna M et al.
DOI: 10.3324/haematol.2017.168401

A Phase Ib, open-label, dose-finding study of alpelisib in combination with paclitaxel in patients with advanced solid tumors.

PMID: 30167089
Journal: Oncotarget
Year: 2018
Reference: Oncotarget. 2018 Aug 3;9(60):31709-31718. doi: 10.18632/oncotarget.25854. eCollection 2018 Aug 3.
Impact factor: 0
Publication type: Clinical Trials
Authors: Han, Yu, Rodon, Jordi, Curigliano, Giuseppe, Delord, Jean-Pierre, Harb, Wael, Azaro, Analia, Sellami, Dalila, Beck, Thaddeus, Donnet, Valerie, Wilke, Celine et al.
DOI: 10.18632/oncotarget.25854

A phase II Study Evaluating Combined Neoadjuvant Cetuximab and Chemotherapy Followed by Chemoradiotherapy and Concomitant Cetuximab in Locoregional Oesophageal Cancer Patients.

PMID: 29128908
Journal: Targeted Oncology
Year: 2018
Reference: Target Oncol. 2018 Feb;13(1):69-78. doi: 10.1007/s11523-017-0536-z.
Impact factor: 3.877
Publication type: Paper in international publication
Authors: Alsina, Maria, Rivera, Fernando, Ramos, Francisco Javier, Galan, Maica, Lopez, Rafael, Garcia-Alfonso, Pilar, Ales-Martinez, Jose Enrique, Queralt, Bernardo, Anton, Antonio, Carrato, Alfredo et al.
DOI: 10.1007/s11523-017-0536-z

A phase I-II study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia.

PMID: 29392425
Journal: ANNALS OF HEMATOLOGY
Year: 2018
Reference: Ann Hematol. 2018 May;97(5):763-772. doi: 10.1007/s00277-018-3229-5. Epub 2018 Feb 2.
Impact factor: 2.845
Publication type: Paper in international publication
Authors: Cordon, Lourdes, Martinez-Cuadron, David, Boluda, Blanca, Martinez, Pilar, Bergua, Juan, Rodriguez-Veiga, Rebeca, Esteve, Jordi, Vives, Susana, Serrano, Josefina, Vidriales, Belen et al.
DOI: 10.1007/s00277-018-3229-5

A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer and Systemic Inflammation.

PMID: 29681434
Journal: Clinical Lung Cancer
Year: 2018
Reference: Clin Lung Cancer. 2018 Sep;19(5):e567-e574. doi: 10.1016/j.cllc.2018.03.016. Epub 2018 Mar 23.
Impact factor: 4.204
Publication type: Paper in international publication
Authors: Waqar, Saiama N, Martinez-Marti, Alex, Ponce, Santiago, Zhen, Huiling, Kennealey, Gerard, Erickson-Viitanen, Susan, Schaefer, Eric, Sanborn, Rachel E, Giaccone, Giuseppe et al.
DOI: 10.1016/j.cllc.2018.03.016

A pragmatic approach for mortality prediction after surgery in infective endocarditis: Optimizing and refining EuroSCORE.

PMID: 29408350
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2018
Reference: Clin Microbiol Infect. 2018 Oct;24(10):1102.e7-1102.e15. doi: 10.1016/j.cmi.2018.01.019. Epub 2018 Mar 3.
Impact factor: 5.394
Publication type: Paper in international publication
Authors: Aznar, Maria L, de Alarcon, Aristides, Garcia-Cabrera, Emilio, Galvez-Acebal, Juan, Sanchez-Espin, Gemma, Reguera-Iglesias, Jose M, De La Torre-Lima, Javier, Lomas, Jose M, Hidalgo-Tenorio, Carmen, Vallejo, Nuria et al.
DOI: 10.1016/j.cmi.2018.01.019

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