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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Health-related quality of life in patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer treated with first-line pembrolizumab versus chemotherapy (KEYNOTE-177): an open-label, randomised, phase 3 trial.

PMID: 33812497
Journal: LANCET ONCOLOGY
Year: 2021
Reference: Lancet Oncol. 2021 May;22(5):665-677. doi: 10.1016/S1470-2045(21)00064-4. Epub 2021 Apr 1.
Impact factor:
Publication type: Paper in international publication
Authors: Amonkar, Mayur; Andre, Thierry; De La Fouchardiere, Christelle; Diaz, Luis A Jr; Elez, Elena; Farooqui, Mohammed; Garcia-Carbonero, Rocio; Jensen, Benny Vittrup; Jensen, Lars Henrik; Kim, Tae Won et al.
DOI: 10.1016/S1470-2045(21)00064-4

Heart Disease in Eosinophilic Granulomatosis with Polyangiitis (EGPA) Patients: a screening approach proposal.

PMID: 33493294
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Oct 2;60(10):4538-4547. doi: 10.1093/rheumatology/keab027.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Garcia-Vives, Eloi, Rodriguez-Palomares, J F, Harty, Len, Solans-Laque, Roser, Jayne, David et al.
DOI: 10.1093/rheumatology/keab027

Heart Disease in Eosinophilic Granulomatosis with Polyangiitis (EGPA) Patients: a screening approach proposal.

PMID: 33493294
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Oct 2;60(10):4538-4547. doi: 10.1093/rheumatology/keab027.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Vives, Eloi; Harty, Len; Jayne, David; Rodriguez-Palomares, J F; Solans-Laque, Roser et al.
DOI: 10.1093/rheumatology/keab027

Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A Case Report.

PMID: 34140949
Journal: Frontiers in Immunology
Year: 2021
Reference: Front Immunol. 2021 Jun 1;12:665824. doi: 10.3389/fimmu.2021.665824. eCollection 2021.
Impact factor: 7.561
Publication type: Letter or abstract
Authors: Ruiz-Rodriguez, Juan Carlos, Chiscano-Camon, Luis, Palmada, Clara, Ruiz-Sanmartin, Adolf, Garcia-de-Acilu, Marina, Plata-Menchaca, Erika, Perurena-Prieto, Janire, Hernandez-Gonzalez, Manuel, Perez-Carrasco, Marcos, Soler-Palacin, Pere et al.
DOI: 10.3389/fimmu.2021.665824

Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A Case Report.

PMID: 34140949
Journal: Frontiers in Immunology
Year: 2021
Reference: Front Immunol. 2021 Jun 1;12:665824. doi: 10.3389/fimmu.2021.665824. eCollection 2021.
Impact factor:
Publication type: Letter or abstract
Authors: Chiscano-Camon, Luis; Ferrer, Ricard; Garcia-de-Acilu, Marina; Hernandez-Gonzalez, Manuel; Palmada, Clara; Perez-Carrasco, Marcos; Perurena-Prieto, Janire; Plata-Menchaca, Erika; Ruiz-Rodriguez, Juan Carlos; Ruiz-Sanmartin, Adolf et al.
DOI: 10.3389/fimmu.2021.665824

Hemodynamic support in septic shock.

PMID: 33652455
Journal: Current Opinion in Anesthesiology
Year: 2021
Reference: Curr Opin Anaesthesiol. 2021 Apr 1;34(2):99-106. doi: 10.1097/ACO.0000000000000959.
Impact factor: 2.706
Publication type: Review in international publication
Authors: Garcia-de-Acilu, Marina, Mesquida, Jaume, Gruartmoner, Guillem, Ferrer, Ricard et al.
DOI: 10.1097/ACO.0000000000000959

Hemodynamic support in septic shock.

PMID: 33652455
Journal: Current Opinion in Anesthesiology
Year: 2021
Reference: Curr Opin Anaesthesiol. 2021 Apr 1;34(2):99-106. doi: 10.1097/ACO.0000000000000959.
Impact factor:
Publication type: Review in international publication
Authors: Ferrer, Ricard; Garcia-de-Acilu, Marina; Gruartmoner, Guillem; Mesquida, Jaume et al.
DOI: 10.1097/ACO.0000000000000959

Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria.

PMID: 33912759
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2021 Feb 3;6(4):1088-1098. doi: 10.1016/j.ekir.2021.01.029. eCollection 2021 Apr.
Impact factor:
Publication type: Paper in international publication
Authors: Ariceta, Gema; Barrios, Kelly; Brown, Bob D; Hoppe, Bernd; Langman, Craig B; Rosskamp, Ralf et al.
DOI: 10.1016/j.ekir.2021.01.029

Hepatic sinusoidal obstruction syndrome associated with nivolumab: an uncommon adverse event related to immune checkpoint inhibitors.

PMID: 33723557
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2021
Reference: J Gastrointestin Liver Dis. 2021 Mar 13;30(1):171-172. doi: 10.15403/jgld-3207.
Impact factor: 2.008
Publication type: Letter whit IF
Authors: Riveiro-Barciela, Mar, Gonzalez-Sans, Didac, Marmolejo, David, Salcedo, Maria-Teresa, Munoz-Couselo, Eva et al.
DOI: 10.15403/jgld-3207

Hepatic sinusoidal obstruction syndrome associated with nivolumab: an uncommon adverse event related to immune checkpoint inhibitors.

PMID: 33723557
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2021
Reference: J Gastrointestin Liver Dis. 2021 Mar 13;30(1):171-172. doi: 10.15403/jgld-3207.
Impact factor:
Publication type: Letter whit IF
Authors: Gonzalez-Sans, Didac; Marmolejo, David; Munoz-Couselo, Eva; Riveiro-Barciela, Mar; Salcedo, Maria-Teresa et al.
DOI: 10.15403/jgld-3207

HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway.

PMID: 34795269
Journal: Nature Communications
Year: 2021
Reference: Nat Commun. 2021 Nov 18;12(1):6667. doi: 10.1038/s41467-021-27093-y.
Impact factor:
Publication type: Paper in international publication
Authors: Arribas, Joaquin; Chandarlapaty, Sarat; de Stanchina, Elisa; Ferraro, Emanuela; Kulick, Amanda; Lahuerta, Enrique J Arenas; Li, Qing; Morales, Cristina Bernado; Razavi, Pedram; Reis-Filho, Jorge et al.
DOI: 10.1038/s41467-021-27093-y

Hereditary angioedema due to C1 inhibitor deficiency: real-world experience from the Icatibant Outcome Survey in Spain.

PMID: 34965883
Journal: Allergy Asthma and Clinical Immunology
Year: 2021
Reference: Allergy Asthma Clin Immunol. 2021 Dec 29;17(1):137. doi: 10.1186/s13223-021-00641-3.
Impact factor: 3.406
Publication type: Paper in international publication
Authors: Guilarte, Mar, Sala-Cunill, Anna, Baeza, Maria Luisa, Cabanas, Rosario, Hernandez, Maria Dolores, Ibanez, Ethel, de Larramendi, Carlos Hernando, Lleonart, Ramon, Lobera, Teofilo, Marques, Luis et al.
DOI: 10.1186/s13223-021-00641-3

Hereditary angioedema due to C1 inhibitor deficiency: real-world experience from the Icatibant Outcome Survey in Spain.

PMID: 34965883
Journal: Allergy Asthma and Clinical Immunology
Year: 2021
Reference: Allergy Asthma Clin Immunol. 2021 Dec 29;17(1):137. doi: 10.1186/s13223-021-00641-3.
Impact factor:
Publication type: Paper in international publication
Authors: Andresen, Irmgard; Baeza, Maria Luisa; Botha, Jaco; Caballero, Teresa; Cabanas, Rosario; de Larramendi, Carlos Hernando; de San Pedro, Blanca Saenz; Guilarte, Mar; Hernandez, Maria Dolores; Ibanez, Ethel et al.
DOI: 10.1186/s13223-021-00641-3

Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue.

PMID: 34312290
Journal: MOLECULAR CANCER RESEARCH
Year: 2021
Reference: Mol Cancer Res. 2021 Nov;19(11):1840-1853. doi: 10.1158/1541-7786.MCR-21-0220. Epub 2021 Jul 26.
Impact factor: 5.852
Publication type: Paper in international publication
Authors: Blommaert, Eline, Herranz, Carmen, Roman, Antonio, Saez, Berta, Ancochea, Julio, Valenzuela, Claudia, Ussetti, Piedad, Laporta, Rosalia, Rodriguez-Portal, Jose A, van Moorsel, Coline H M et al.
DOI: 10.1158/1541-7786.MCR-21-0220

Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue.

PMID: 34312290
Journal: MOLECULAR CANCER RESEARCH
Year: 2021
Reference: Mol Cancer Res. 2021 Nov;19(11):1840-1853. doi: 10.1158/1541-7786.MCR-21-0220. Epub 2021 Jul 26.
Impact factor:
Publication type: Paper in international publication
Authors: Ancochea, Julio; Baiges, Alexandra; Blommaert, Eline; Casanova, Alvaro; Diaz-Lucena, Daniela; Espin, Roderic; Herranz, Carmen; Laporta, Rosalia; Llorens, Franc; Mateo, Francesca et al.
DOI: 10.1158/1541-7786.MCR-21-0220

Heterogeneity is a common ground in familial hypomagnesemia with hypercalciuria and nephrocalcinosis caused by CLDN19 gene mutations.

PMID: 33929692
Journal: JOURNAL OF NEPHROLOGY
Year: 2021
Reference: J Nephrol. 2021 Dec;34(6):2053-2062. doi: 10.1007/s40620-021-01054-6. Epub 2021 Apr 30.
Impact factor:
Publication type: Paper in international publication
Authors: Ariceta, Gema; Burballa, Carla; Claverie-Martin, Felix; Meseguer, Anna; Vall-Palomar, Monica et al.
DOI: 10.1007/s40620-021-01054-6

Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms.

PMID: 33880889
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2021
Reference: Clin Exp Allergy. 2021 Aug;51(8):1033-1045. doi: 10.1111/cea.13884. Epub 2021 May 11.
Impact factor: 5.018
Publication type: Paper in international publication
Authors: Bousquet, Jean, Schroder-Bernhardi, Detlef, Bachert, Claus, Costa, Elisio M, Czarlewski, Wienczyslawa, Devillier, Philippe, Fonseca, Joao, Klimek, Ludger, Kuna, Piotr, Lourenco, Olga et al.
DOI: 10.1111/cea.13884

Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms.

PMID: 33880889
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2021
Reference: Clin Exp Allergy. 2021 Aug;51(8):1033-1045. doi: 10.1111/cea.13884. Epub 2021 May 11.
Impact factor:
Publication type: Paper in international publication
Authors: Bachert, Claus; Bousquet, Jean; Canonica, Giorgio W; Cardona, Victoria; Costa, Elisio M; Czarlewski, Wienczyslawa; Devillier, Philippe; Fonseca, Joao; Klimek, Ludger; Kuna, Piotr et al.
DOI: 10.1111/cea.13884

High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib.

PMID: 33414483
Journal: LEUKEMIA
Year: 2021
Reference: Leukemia. 2021 Feb;35(2):485-493. doi: 10.1038/s41375-020-01107-y. Epub 2021 Jan 7.
Impact factor: 11.528
Publication type: Paper in international publication
Authors: Barbui, Tiziano, Vannucchi, Alessandro Maria, Alvarez-Larran, Alberto, Iurlo, Alessandra, Masciulli, Arianna, Carobbio, Alessandra, Ghirardi, Arianna, Ferrari, Alberto, Rossi, Giuseppe, Elli, Elena et al.
DOI: 10.1038/s41375-020-01107-y

High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib.

PMID: 33414483
Journal: LEUKEMIA
Year: 2021
Reference: Leukemia. 2021 Feb;35(2):485-493. doi: 10.1038/s41375-020-01107-y. Epub 2021 Jan 7.
Impact factor:
Publication type: Paper in international publication
Authors: Abadia, Emma Lopez; Alvarez-Larran, Alberto; Andrade-Campos, Marcio Miguel; Angona, Anna; Barbui, Tiziano; Bellini, Marta; Bellosillo, Beatriz; Benajiba, Lina; Benevolo, Giulia; Betti, Silvia et al.
DOI: 10.1038/s41375-020-01107-y

High Mutational Heterogeneity, and New Mutations in the Human Coagulation Factor V Gene. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies.

PMID: 34575869
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Sep 8;22(18). pii: ijms22189705. doi: 10.3390/ijms22189705.
Impact factor: 5.924
Publication type: Paper in international publication
Authors: Bernal, Sara, Pelaez, Irene, Alias, Laura, Baena, Manel, De Pablo-Moreno, Juan A, Serrano, Luis J, Camero, M Dolores, Tizzano, Eduardo F, Berrueco, Ruben, Liras, Antonio et al.
DOI: 10.3390/ijms22189705

High Mutational Heterogeneity, and New Mutations in the Human Coagulation Factor V Gene. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies.

PMID: 34575869
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Sep 8;22(18). pii: ijms22189705. doi: 10.3390/ijms22189705.
Impact factor:
Publication type: Paper in international publication
Authors: Alias, Laura; Baena, Manel; Bernal, Sara; Berrueco, Ruben; Camero, M Dolores; De Pablo-Moreno, Juan A; Liras, Antonio; Pelaez, Irene; Serrano, Luis J; Tizzano, Eduardo F et al.
DOI: 10.3390/ijms22189705

High rate of infections during ICU admission of patients with severe SARS-CoV-2 pneumonia: a matter of time?

PMID: 33285217
Journal: JOURNAL OF INFECTION
Year: 2021
Reference: J Infect. 2021 May;82(5):186-230. doi: 10.1016/j.jinf.2020.12.001. Epub 2020 Dec 5.
Impact factor:
Publication type: Letter or abstract
Authors: Barrasa, Helena; Canut-Blasco, Andres; Fernandez-Torres, Marina; Martin, Alejandro; Maynar, Javier; Quinonero, Amaia Aguirre-; Rello, Jordi et al.
DOI: 10.1016/j.jinf.2020.12.001

Higher agreement in endovascular treatment decision-making than in parametric quantifications among automated CT perfusion software packages in acute ischemic stroke.

PMID: 34334443
Journal: Journal of X-Ray Science and Technology
Year: 2021
Reference: J Xray Sci Technol. 2021;29(5):823-834. doi: 10.3233/XST-210898.
Impact factor: 1.535
Publication type: Paper in international publication
Authors: Perez-Pelegri, Manuel, Biarnes, Carles, Thio-Henestrosa, Santiago, Remollo, Sebastia, Gimeno, Alfredo, Cuba, Victor, Teceno, Mikel, Serena, Joaquin, Pedraza, Salvador, Ruiz-Constantino, Juan Sebastian et al.
DOI: 10.3233/XST-210898