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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

ALSUntangled No. 35: Hyperbaric Oxygen Therapy.

PMID: 27089115
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2016
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2016 Oct - Nov;17(7-8):622-624. doi: 10.3109/21678421.2016.1172818. Epub 2016 Apr 18.
Impact factor: 2.677
Publication type: Review in international publication
Authors: Gamez, Josep et al.
DOI: 10.3109/21678421.2016.1172818

Alteration of the serum microbiome composition in cirrhotic patients with ascites.

PMID: 27112233
Journal: Scientific Reports
Year: 2016
Reference: Sci Rep. 2016 Apr 26;6:25001. doi: 10.1038/srep25001.
Impact factor: 5.228
Publication type: Paper in international publication
Authors: Gely, Cristina, Santiago, Alba, Pozuelo, Marta, Poca, Maria, Roman, Eva, Campos, David, Sarrabayrouse, Guillaume, Vidal, Silvia, Alvarado-Tapias, Edilmar, Guarner, Francisco et al.
DOI: 10.1038/srep25001

Altered Underlying Renal Tubular Function in Patients With Chronic Hepatitis B Receiving Nucleos(t)ide Analogs in a Real-World Setting: The MENTE Study.

PMID: 27332746
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2016
Reference: J Clin Gastroenterol. 2016 Oct;50(9):779-89. doi: 10.1097/MCG.0000000000000569.
Impact factor: 3.163
Publication type: Paper in international publication
Authors: Rodriguez-Novoa, Sonia, Garcia-Samaniego, Javier, Prieto, Martin, Calleja, Jose L, Pascasio, Juan M, Delgado Blanco, Manuel, Crespo, Javier, Buti, Maria, Bonet Vidal, Maria L, Arenas Ruiz Tapiador, Juan et al.
DOI: 10.1097/MCG.0000000000000569

AME evidence series 001-The Society for Translational Medicine: clinical practice guidelines for diagnosis and early identification of sepsis in the hospital.

PMID: 27747021
Journal: Journal of Thoracic Disease
Year: 2016
Reference: J Thorac Dis. 2016 Sep;8(9):2654-2665.
Impact factor: 1.649
Publication type: Review in international publication
Authors: Yu, Yuetian, Jung, Christian, Robba, Chiara, Taccone, Fabio Silvio, Caironi, Pietro, Grimaldi, David, Hofer, Stefan, Dimopoulos, George, Leone, Marc, Hong, Sang-Bum et al.
DOI: 10.21037/jtd.2016.08.03

An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules.

PMID: 26361993
Journal: JOURNAL OF CLINICAL EPIDEMIOLOGY
Year: 2016
Reference: J Clin Epidemiol. 2016 Jan;69:152-60. doi: 10.1016/j.jclinepi.2015.05.023. Epub 2015 Jun 4.
Impact factor: 4.703
Publication type: Review in national publication
Authors: Neumann, Ignacio, Carrasco-Labra, Alonso, Faulhaber, Markus, Mulla, Sohail, Mertz, Dominik, Akl, Elie A, Bassler, Dirk, Busse, Jason W, Ferreira-Gonzalez, Ignacio, Lamontagne, Francois et al.
DOI: 10.1016/j.jclinepi.2015.05.023

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

PMID: 27959928
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Dec 13;11(12):e0166902. doi: 10.1371/journal.pone.0166902. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Martin, Veronica, Perales, Celia, Fernandez-Algar, Maria, Dos Santos, Helena G, Garrido, Patricia, Pernas, Maria, Parro, Victor, Moreno, Miguel, Garcia-Perez, Javier, Alcami, Jose et al.
DOI: 10.1371/journal.pone.0166902

An exploratory study comparing psychological profiles and its congruence with clinical performance among patients with functional or motility digestive disorders.

PMID: 25921480
Journal: Journal of health psychology
Year: 2016
Reference: J Health Psychol. 2016 Nov;21(11):2590-2599. doi: 10.1177/1359105315581069. Epub 2016 Jul 9.
Impact factor:
Publication type: Letter or abstract
Authors: Azpiroz, Fernando, Parramon, Gemma, Santamarina-Perez, Pilar, Accarino, Anna, Rodriguez-Urrutia, Amanda, Eiroa-Orosa, Francisco Jose et al.
DOI: 10.1177/1359105315581069

An innovative and collaborative partnership between patients with rare disease and industry-supported registries: the Global aHUS Registry.

PMID: 27871301
Journal: Orphanet Journal of Rare Diseases
Year: 2016
Reference: Orphanet J Rare Dis. 2016 Nov 21;11(1):154.
Impact factor: 3.29
Publication type: Review in national publication
Authors: Gasteyger, Christoph, Licht, Christoph, Ariceta, Gema, Beck, Joran, Walle, Johan Vande, Woodward, Len, Johnson, Sally et al.
DOI: 10.1186/s13023-016-0537-5

An international consensus approach to the management of atypical hemolytic uremic syndrome in children.

PMID: 25859752
Journal: PEDIATRIC NEPHROLOGY
Year: 2016
Reference: Pediatr Nephrol. 2016 Jan;31(1):15-39. doi: 10.1007/s00467-015-3076-8. Epub 2015 Apr 11.
Impact factor: 2.338
Publication type: Review in international publication
Authors: Fakhouri, Fadi, Ariceta, Gema, Besbas, Nesrin, Bitzan, Martin, Bjerre, Anna, Coppo, Rosanna, Emma, Francesco, Johnson, Sally, Karpman, Diana, Landau, Daniel et al.
DOI: 10.1007/s00467-015-3076-8

An Open-Label Trial of 12-Week Simeprevir plus Peginterferon/Ribavirin (PR) in Treatment-Naive Patients with Hepatitis C Virus (HCV) Genotype 1 (GT1).

PMID: 27428331
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jul 18;11(7):e0158526. doi: 10.1371/journal.pone.0158526. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Buggisch, Peter, Ryan, Robert, Lenz, Oliver, Scott, Jane, Van Dooren, Gino, Lonjon-Domanec, Isabelle, Schlag, Michael, Buti, Maria, Craxi, Antonio, Foster, Graham R et al.
DOI: 10.1371/journal.pone.0158526

An uncommon first manifestation of multiple sclerosis: Tako-Tsubo cardiomyopathy.

PMID: 26993120
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 May;22(6):842-6. doi: 10.1177/1352458516638557. Epub 2016 Mar 18.
Impact factor: 4.671
Publication type: Paper in international publication
Authors: Midaglia, Luciana, Juega Marino, Jesus M, Sastre-Garriga, Jaume, Rovira, Alex, Vidal-Jordana, Angela, Lopez-Perez, Maria A, Marzo-Sola, Maria E, Librada Escribano, Fausto, Montalban, Xavier et al.
DOI: 10.1177/1352458516638557

Analysis of cerebrovascular mortality trends in Spain from 1980 to 2011.

PMID: 25524042
Journal: NEUROLOGIA
Year: 2016
Reference: Neurologia. 2016 Jul-Aug;31(6):370-8. doi: 10.1016/j.nrl.2014.09.002. Epub 2014 Dec 15.
Impact factor: 1.289
Publication type: Paper in national publication
Authors: Cayuela, A, Escudero-Martinez, I, Rodriguez-Dominguez, S, Gonzalez, A, Moniche, F, Jimenez, M D, Montaner, J, Cayuela, L et al.
DOI: 10.1016/j.nrl.2014.09.002

Analysis of expression of PTEN/PI3K pathway and programmed cell death ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM).

PMID: 27133741
Journal: LUNG CANCER
Year: 2016
Reference: Lung Cancer. 2016 Jun;96:1-6. doi: 10.1016/j.lungcan.2016.03.001. Epub 2016 Mar 10.
Impact factor: 3.767
Publication type: Paper in international publication
Authors: Cedres, S, Ponce-Aix, S, Pardo-Aranda, N, Navarro-Mendivil, A, Martinez-Marti, A, Zugazagoitia, J, Sansano, I, Montoro, M A, Enguita, A, Felip, E et al.
DOI: 10.1016/j.lungcan.2016.03.001

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

PMID: 27194806
Journal: G3-Genes Genomes Genetics
Year: 2016
Reference: G3 (Bethesda). 2016 Jul 7;6(7):2073-9. doi: 10.1534/g3.116.030841.
Impact factor: 2.91
Publication type: Paper in international publication
Authors: Akkad, Denis A, Aktas, Orhan, Blaschke, Paul, Buttmann, Mathias, Chan, Andrew, Epplen, Joerg T, Gerdes, Lisa-Ann, Kroner, Antje, Kubisch, Christian, Kumpfel, Tania et al.
DOI: 10.1534/g3.116.030841

Analysis of the reliability of surgeons' ability to differentiate between idiopathic and degenerative spinal deformity in adults radiologically. What descriptive parameters help them decide?

PMID: 26769036
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Aug;25(8):2401-7. doi: 10.1007/s00586-015-4366-3. Epub 2016 Jan 14.
Impact factor: 2.132
Publication type: Paper in international publication
Authors: Guler, Umit Ozgur, Yuksel, Selcen, Yakici, Sule, Domingo-Sabat, Montserrat, Pellise, Ferran, Perez-Grueso, Francisco J S, Obeid, Ibrahim, Kleinstuck, Frank, Acaroglu, Emre, Alanay, Ahmet et al.
DOI: 10.1007/s00586-015-4366-3

ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION: A Natural History Study From the Pan American Collaborative Retina Study Group.

PMID: 26966868
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2016
Reference: Retina. 2016 Oct;36(10):1913-8. doi: 10.1097/IAE.0000000000001015.
Impact factor:
Publication type: Paper in international publication
Authors: Alezzandrini, Arturo; Arevalo, J Fernando; Avila, Marcos; Badal, Josep; Berrocal, Maria H; Chhablani, Jay; Collado, Alberto; Dalma-Weishauz, Jose; Figueroa, Marta; Fromow-Guerra, Jans et al.
DOI: 10.1097/IAE.0000000000001015

Angiogenic Factors and Doppler Evaluation in Normally Growing Fetuses at Routine Third-Trimester Scan: Prediction of Subsequent Low Birth Weight.

PMID: 26421431
Journal: FETAL DIAGNOSIS AND THERAPY
Year: 2016
Reference: Fetal Diagn Ther. 2016;40(1):13-20. doi: 10.1159/000440650. Epub 2015 Oct 1.
Impact factor: 2.939
Publication type: Paper in international publication
Authors: Triunfo, Stefania, Parra-Saavedra, Miguel, Rodriguez-Sureda, Victor, Crovetto, Francesca, Dominguez, Carmen, Gratacos, Eduard, Figueras, Francesc et al.
DOI: 10.1159/000440650

Angiogenic Gene Expression in Down Syndrome Fetal Hearts.

PMID: 26513650
Journal: FETAL DIAGNOSIS AND THERAPY
Year: 2016
Reference: Fetal Diagn Ther. 2016;40(1):21-7. doi: 10.1159/000441356. Epub 2015 Oct 30.
Impact factor: 2.7
Publication type: Paper in international publication
Authors: Sanchez, Olga, Dominguez, Carmen, Ruiz, Aina, Ribera, Irene, Alijotas, Jaume, Cabero, Lluis, Carreras, Elena, Llurba, Elisa et al.
DOI: 10.1159/000441356

Answer to the Letter to the Editor of L. P. Ardigo et al. concerning "Validity and reliability of photographic measures to evaluate waistline asymmetry in idiopathic scoliosis" by Matamalas A, Bago J, D Agata E, Pellise F (2016) Eur Spine J; 2016 Mar 14 [Epub ahead of print].

PMID: 27421280
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Sep;25(9):3019-20. doi: 10.1007/s00586-016-4689-8.
Impact factor: 2.132
Publication type: Letter or abstract
Authors: Adrover, Antonia Matamalas et al.
DOI: 10.1007/s00586-016-4689-8

Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke.

PMID: 27301579
Journal: GLIA
Year: 2016
Reference: Glia. 2016 Sep;64(9):1492-507. doi: 10.1002/glia.23017. Epub 2016 Jun 15.
Impact factor: 5.997
Publication type: Paper in international publication
Authors: Lemarchant, Sighild, Dunghana, Hiramani, Pomeshchik, Yuriy, Leinonen, Henri, Kolosowska, Natalia, Korhonen, Paula, Kanninen, Katja M, Garcia-Berrocoso, Teresa, Montaner, Joan, Malm, Tarja et al.
DOI: 10.1002/glia.23017

Anti-MDA5 dermatomyositis and progressive interstitial pneumonia.

PMID: 25784769
Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Year: 2016
Reference: QJM. 2016 Jan;109(1):49-50. doi: 10.1093/qjmed/hcv068. Epub 2015 Mar 16.
Impact factor: 2.495
Publication type: Paper in international publication
Authors: Silveira, M G, Selva-O'Callaghan, A, Ramos-Terrades, N, Arredondo-Agudelo, K V, Labrador-Horrillo, M, Bravo-Masgoret, C et al.
DOI: 10.1093/qjmed/hcv068

Antiplatelet therapy versus observation in low-risk essential thrombocythemia with CALR mutation.

PMID: 27175028
Journal: HAEMATOLOGICA
Year: 2016
Reference: Haematologica. 2016 Aug;101(8):926-31. doi: 10.3324/haematol.2016.146654. Epub 2016 May 12.
Impact factor: 6.671
Publication type: Paper in international publication
Authors: Gomez-Casares, Maria Teresa, Paoli, Chiara, Drexler, Beatrice, Zweegman, Sonja, McMullin, Mary F, Samuelsson, Jan, Harrison, Claire, Cervantes, Francisco, Vannucchi, Alessandro M, Besses, Carlos et al.
DOI: 10.3324/haematol.2016.146654

Antistaphylococcal beta-Lactams versus Vancomycin for Treatment of Infective Endocarditis Due to Methicillin-Susceptible Coagulase-Negative Staphylococci: a Prospective Cohort Study from the International Collaboration on Endocarditis.

PMID: 27527083
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2016
Reference: Antimicrob Agents Chemother. 2016 Sep 23;60(10):6341-9. doi: 10.1128/AAC.01531-16. Print 2016 Oct.
Impact factor: 4.415
Publication type: Paper in international publication
Authors: Carugati, M, Petti, C A, Arnold, C, Miro, J M, Pericas, J M, Garcia de la Maria, C, Kanafani, Z, Durante-Mangoni, E, Baddley, J, Wray, D et al.
DOI: 10.1128/AAC.01531-16

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.

PMID: 27428438
Journal: EBioMedicine
Year: 2016
Reference: EBioMedicine. 2016 Jun;8:291-301. doi: 10.1016/j.ebiom.2016.05.006. Epub 2016 May 8.
Impact factor: 0
Publication type: Paper in international publication
Authors: Dhar, Neeraj, Signorino-Gelo, Francois, McKinney, John D, Garcia-Bustos, Jose Francisco, Lavandera, Jose Luis, Sacchettini, James C, Jimenez, M Soledad, Martin-Casabona, Nuria, Castro-Pichel, Julia, Mendoza-Losana, Alfonso et al.
DOI: 10.1016/j.ebiom.2016.05.006