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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

AAV-mediated expression of secreted and transmembrane alphaKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice.

PMID: 35274439
Journal: AGING CELL
Year: 2022
Reference: Aging Cell. 2022 Apr;21(4):e13581. doi: 10.1111/acel.13581. Epub 2022 Mar 10.
Impact factor: 9.304
Publication type: Paper in international publication
Authors: Bosch, A, Pallas, M, Chillon, Miguel, Abraham, C R, Espinosa-Parrilla, J F, Roig-Soriano, J, Grinan-Ferre, C et al.
DOI: 10.1111/acel.13581

Abdominal normothermic regional perfusion in controlled DCD liver transplantation: outcomes and risk factors for graft loss.

PMID: 34856070
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Apr;22(4):1169-1181. doi: 10.1111/ajt.16899. Epub 2021 Dec 21.
Impact factor: 8.086
Publication type: Paper in international publication
Authors: Barrera, Manuel, Villegas Herrera, Maria Trinidad, Villar Del Moral, Jesus, Gonzalez-Abos, Carolina, Vidal, Barbara, Lopez-Dominguez, Josefina, Llado, Laura, Roldan, Jose, Justo, Iago, Jimenez, Carlos et al.
DOI: 10.1111/ajt.16899

Abdominal versus perineal approach for external rectal prolapse: systematic review with meta-analysis.

PMID: 35390136
Journal: BJS Open
Year: 2022
Reference: BJS Open. 2022 Mar 8;6(2). pii: 6564775. doi: 10.1093/bjsopen/zrac018.
Impact factor: 3.396
Publication type: Review in international publication
Authors: Pellino, Gianluca, Fuschillo, Giacomo, Simillis, Costantinos, Selvaggi, Lucio, Signoriello, Giuseppe, Vinci, Danilo, Kontovounisios, Christos, Selvaggi, Francesco, Sciaudone, Guido et al.
DOI: 10.1093/bjsopen/zrac018

Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 x 2 factorial design.

PMID: 35405085
Journal: LANCET
Year: 2022
Reference: Lancet. 2022 Apr 30;399(10336):1695-1707. doi: 10.1016/S0140-6736(22)00367-1. Epub 2022 Apr 8.
Impact factor: 79.323
Publication type: Paper in international publication
Authors: Schlurmann, Friederike, Flechon, Aude, Tombal, Bertrand, Supiot, Stephane, Berthold, Dominik, Ronchin, Philippe, Kacso, Gabriel, Gravis, Gwenaelle, Calabro, Fabio, Berdah, Jean-Francois et al.
DOI: 10.1016/S0140-6736(22)00367-1

Accelerated Surgery Versus Standard Care in Hip Fracture (HIP ATTACK-1): A Kidney Substudy of a Randomized Clinical Trial.

PMID: 35346742
Journal: AMERICAN JOURNAL OF KIDNEY DISEASES
Year: 2022
Reference: Am J Kidney Dis. 2022 Mar 26. pii: S0272-6386(22)00551-0. doi: 10.1053/j.ajkd.2022.01.431.
Impact factor: 8.86
Publication type: Letter whit IF
Authors: Nur, Aamer Nabi, Wood, Gavin C A, Feibel, Robert J, McMahon, John Stephen, Biccard, Bruce M, Ortalda, Alessandro, Szczeklik, Wojciech, Wang, Chew Yin, Tomas-Hernandez, Jordi, Vincent, Jessica et al.
DOI: 10.1053/j.ajkd.2022.01.431

Acceptability and participation predictors for a pragmatic randomized controlled trial to test a smoking cessation intervention after discharge from mental health wards.

PMID: 35278807
Journal: DRUG AND ALCOHOL DEPENDENCE
Year: 2022
Reference: Drug Alcohol Depend. 2022 May 1;234:109390. doi: 10.1016/j.drugalcdep.2022.109390. Epub 2022 Mar 3.
Impact factor: 4.492
Publication type: Paper in international publication
Authors: Martinez, Cristina, Feliu, Ariadna, Torres, Nuria, Nieva, Gemma, Pinet, Cristina, Raich, Antonia, Mondon, Silvia, Barrio, Pablo, Andreu, Magali, Hernandez-Ribas, Rosa et al.
DOI: 10.1016/j.drugalcdep.2022.109390

Access to early-phase clinical trials for children with relapsed and refractory neuroblastoma: A multicentre international study.

PMID: 35029330
Journal: PEDIATRIC BLOOD & CANCER
Year: 2022
Reference: Pediatr Blood Cancer. 2022 Aug;69(8):e29551. doi: 10.1002/pbc.29551. Epub 2022 Jan 14.
Impact factor: 3.167
Publication type: Paper in international publication
Authors: Cortes, Marta, Carceller, Fernando, Rubio-San-Simon, Alba, Vaidya, Sucheta J, Bautista, Francisco, Moreno, Lucas et al.
DOI: 10.1002/pbc.29551

Activity and resistance of a brain-permeable paradox breaker BRAF inhibitor in melanoma brain metastasis.

PMID: 35584009
Journal: CANCER RESEARCH
Year: 2022
Reference: Cancer Res. 2022 May 18. pii: 699020. doi: 10.1158/0008-5472.CAN-21-4152.
Impact factor: 12.701
Publication type: Paper in international publication
Authors: Ferres-Pijoan, Abel, Bonfill-Teixidor, Ester, Iurlaro, Raffaella, Handl, Cornelia, Wichmann, Jurgen, Arias, Alexandra, Cuartas, Isabel, Emmenegger, Jasmin, Romagnani, Andrea, Mangano, Luca et al.
DOI: 10.1158/0008-5472.CAN-21-4152

Acute heart failure. The quintessential cardiac emergency.

PMID: 34483064
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2022
Reference: Rev Esp Cardiol. 2022 Jan;75(1):9-11. doi: 10.1016/j.rec.2021.06.017. Epub 2021 Sep 3.
Impact factor: 4.753
Publication type: Editorial in national publication
Authors: Pena-Gil, Carlos; Gonzalez-Salvado, Violeta; Figueras-Bellot, Jaume et al.
DOI: 10.1016/j.rec.2021.06.017

Acute hepatitis a in international Travelers: A GeoSentinel analysis, 2008-2020.

PMID: 35134210
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2022
Reference: J Travel Med. 2022 Mar 21;29(2). pii: 6520887. doi: 10.1093/jtm/taac013.
Impact factor: 8.49
Publication type: Paper in international publication
Authors: Balogun, Oluwafemi; Brown, Ashley; Angelo DO, Kristina M; Hochberg, Natasha S; Barnett, Elizabeth D; Nicolini, Laura Ambra; Asgeirsson, Hilmir; Grobusch, Martin P; Leder, Karin; Salvador, Fernando et al.
DOI: 10.1093/jtm/taac013

Acute kidney injury as a risk factor for mortality in oncological patients receiving check-point inhibitors.

PMID: 33547795
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Apr 25;37(5):887-894. doi: 10.1093/ndt/gfab034.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Garcia-Carro, Clara, Bolufer, Monica, Bury, Roxana, Cataneda, Zaira, Munoz, Eva, Felip, Enriqueta, Lorente, David, Josep Carreras, Maria, Gabaldon, Alejandra, Seron, Daniel et al.
DOI: 10.1093/ndt/gfab034

ADAGIO: a phase IIb international study of the Wee1 inhibitor adavosertib in women with recurrent or persistent uterine serous carcinoma.

PMID: 34716177
Journal: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Year: 2022
Reference: Int J Gynecol Cancer. 2022 Jan;32(1):89-92. doi: 10.1136/ijgc-2021-003144. Epub 2021 Oct 29.
Impact factor: 3.437
Publication type: Paper in international publication
Authors: Liu, Joyce; Oza, Amit M; Colombo, Nicoletta; Oaknin, Ana et al.
DOI: 10.1136/ijgc-2021-003144

Adaptive immune signature in HER2-positive breast cancer in NCCTG (Alliance) N9831 and NeoALTTO trials.

PMID: 35610260
Journal: npj Breast Cancer
Year: 2022
Reference: NPJ Breast Cancer. 2022 May 24;8(1):68. doi: 10.1038/s41523-022-00430-0.
Impact factor: 6.923
Publication type: Paper in international publication
Authors: Norton, Nadine, Chumsri, Saranya, Li, Zhuo, Serie, Daniel J, Brauer, Heather Ann, Warren, Sarah, Danaher, Patrick, Colon-Otero, Gerardo, Partridge, Ann H, Carey, Lisa A et al.
DOI: 10.1038/s41523-022-00430-0

Added value of patient-reported outcome measures (PROMs) after an acute stroke and early predictors of 90 days PROMs.

PMID: 35695977
Journal: Journal of patient-reported outcomes
Year: 2022
Reference: J Patient Rep Outcomes. 2022 Jun 13;6(1):66. doi: 10.1186/s41687-022-00472-9.
Impact factor: 0
Publication type: Paper in international publication
Authors: Montiel, Estefania, Baladas, Maria, Lallanas, Sofia, Aurin, Eva, Watson, Carolina, Gutierrez, Maria, Cossio, Yolima, Ribo, Marc, Molina, Carlos A, Rubiera, Marta et al.
DOI: 10.1186/s41687-022-00472-9

Addition of Immune Checkpoint Inhibitors to Chemotherapy vs Chemotherapy Alone as First-Line Treatment in Extensive-Stage Small-Cell Lung Carcinoma: A Systematic Review and Meta-Analysis.

PMID: 35032007
Journal: Oncology and therapy
Year: 2022
Reference: Oncol Ther. 2022 Jun;10(1):167-184. doi: 10.1007/s40487-021-00182-0. Epub 2022 Jan 15.
Impact factor: 0
Publication type: Review in international publication
Authors: Isla, Dolores, Crama, Leonardo, Mosquera, Joaquin, Arriola, Edurne, Gonzalez-Cao, Maria, Domine, Manuel, De Castro, Javier, Cobo, Manuel, Bernabe, Reyes, Navarro, Alejandro et al.
DOI: 10.1007/s40487-021-00182-0

Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial.

PMID: 35144989
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2022
Reference: Eur Respir J. 2022 Mar 10;59(3). pii: 13993003.03036-2021. doi: 10.1183/13993003.03036-2021. Print 2022 Mar.
Impact factor: 16.671
Publication type: Letter whit IF
Authors: Agusti, Alvar; Munoz, Xavier; Romero-Mesones, Christian; Sibila, Oriol; Lopez-Giraldo, Alejandra; Moral, Vicente Plaza; Curto, Elena; Echazarreta, Andres L; Marquez, Silvana E; Pascual-Guardia, Sergi et al.
DOI: 10.1183/13993003.03036-2021

Adherence improvement in patients with ulcerative colitis: a multidisciplinary consensus document.

PMID: 34254522
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2022
Reference: Rev Esp Enferm Dig. 2022 Mar;114(3):156-165. doi: 10.17235/reed.2021.8130/2021.
Impact factor: 2.086
Publication type: Paper in national publication
Authors: Bella Castillo, Pablo, Barreiro-de Acosta, Manuel, Gomez, Susana, Fortes, Pilar, Camacho, Laura, Casellas, Francesc, Gonzalez-Lama, Yago, Ginard Vicens, Daniel, Garcia-Lopez, Santiago, Munoz, Fernando et al.
DOI: 10.17235/reed.2021.8130/2021

Adipose tissue-specific ablation of PGC-1beta impairs thermogenesis in brown fat.

PMID: 35466996
Journal: Disease Models & Mechanisms
Year: 2022
Reference: Dis Model Mech. 2022 Apr 1;15(4). pii: 275113. doi: 10.1242/dmm.049223. Epub 2022 Apr 25.
Impact factor: 5.758
Publication type: Paper in international publication
Authors: Funda, Jiri, Villena, Josep A, Bardova, Kristina, Adamcova, Katerina, Irodenko, Illaria, Flachs, Pavel, Jedlickova, Ivana, Haasova, Eliska, Rossmeisl, Martin, Kopecky, Jan et al.
DOI: 10.1242/dmm.049223

Adjacent segment syndrome after failed back surgery: biomechanics, diagnosis, and treatment.

PMID: 34709016
Journal: Minerva Anestesiologica
Year: 2022
Reference: Minerva Anestesiol. 2022 Apr;88(4):282-292. doi: 10.23736/S0375-9393.21.15939-5. Epub 2021 Oct 28.
Impact factor: 3.051
Publication type: Paper in international publication
Authors: Rubio-Haro, Ruben, De Andres-Serrano, Carmen, Noriega Gonzalez, David C, Bordes-Garcia, Clara, DE Andres, Jose et al.
DOI: 10.23736/S0375-9393.21.15939-5

Adjuvant therapy in early-stage cervical cancer after radical hysterectomy: are we overtreating our patients? A meta-analysis.

PMID: 35441353
Journal: Clinical & Translational Oncology
Year: 2022
Reference: Clin Transl Oncol. 2022 Aug;24(8):1605-1614. doi: 10.1007/s12094-022-02808-9. Epub 2022 Apr 19.
Impact factor: 3.405
Publication type: Review in international publication
Authors: Gomez-Hidalgo, Natalia R, Acosta, Ursula, Rodriguez, Tomas Gomez, Mico, Soraya, Verges, Ramona, Conesa, Vicente Bebia, Bradbury, Melissa, Perez-Hoyos, Santiago, Perez-Benavente, Asuncion, Gil-Moreno, Antonio et al.
DOI: 10.1007/s12094-022-02808-9

Adolescents and young adults with rhabdomyosarcoma treated in the European paediatric Soft tissue sarcoma Study Group (EpSSG) protocols: a cohort study.

PMID: 35690071
Journal: Lancet Child & Adolescent Health
Year: 2022
Reference: Lancet Child Adolesc Health. 2022 Aug;6(8):545-554. doi: 10.1016/S2352-4642(22)00121-3. Epub 2022 Jun 9.
Impact factor: 11.288
Publication type: Paper in international publication
Authors: Defachelles, Anne-Sophie, Coppadoro, Beatrice, Bisogno, Gianni, Merks, Johannes H M, Devalck, Christine, Mandeville, Henry C, Alaggio, Rita, Ferrari, Andrea, Chisholm, Julia C, Jenney, Meriel et al.
DOI: 10.1016/S2352-4642(22)00121-3

Advanced Glycations End Products in the Skin as Biomarkers of Cardiovascular Risk in Type 2 Diabetes.

PMID: 35682915
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2022
Reference: Int J Mol Sci. 2022 Jun 2;23(11). pii: ijms23116234. doi: 10.3390/ijms23116234.
Impact factor: 5.924
Publication type: Review in international publication
Authors: Planas, Alejandra, Simo-Servat, Olga, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.3390/ijms23116234

Advances and Pitfalls of Specialized Pain Care through Public and Private Health Care Providers in Catalonia and the Balearic Islands: A Physician's Survey.

PMID: 35637851
Journal: Pain Research & Management
Year: 2022
Reference: Pain Res Manag. 2022 May 21;2022:4077139. doi: 10.1155/2022/4077139. eCollection 2022.
Impact factor: 3.037
Publication type: Paper in international publication
Authors: Medel, Javier, Serrano, Ancor, Batet, Carme, Lorente, Lluis, Bella, Susana, Ferrandiz, Marta, Monerris, Maria-Del-Mar, Boada, Sergi, Villoria, Jesus, Ribera, Maria-Victoria et al.
DOI: 10.1155/2022/4077139

Advances in the systemic treatment of therapeutic approaches in biliary tract cancer.

PMID: 35696747
Journal: ESMO Open
Year: 2022
Reference: ESMO Open. 2022 Jun;7(3):100503. doi: 10.1016/j.esmoop.2022.100503. Epub 2022 Jun 10.
Impact factor: 6.54
Publication type: Review in international publication
Authors: Mirallas, O, Lopez-Valbuena, D , Garcia-Illescas, D, Fabregat-Franco, C, Verdaguer, H, Tabernero, J, Macarulla, T et al.
DOI: 10.1016/j.esmoop.2022.100503